Mycotoxins最新文献_第5页

Changes in the concentration of mycotoxins in forage rice and pathogenicity of the causal fungus. 饲料水稻真菌毒素浓度的变化及致病真菌的致病性。

Mycotoxins Pub Date : 2015-01-31 DOI: 10.2520/MYCO.65.45

R. Uegaki

引用次数: 0

Recent progress in research and control of Fusarium head blight in wheat in Hokkaido 北海道小麦赤霉病研究与防治进展

Mycotoxins Pub Date : 2015-01-31 DOI: 10.2520/MYCO.65.31

J. Souma

引用次数: 0

Production of reactive oxygen species in Aspergillus nidulans through the function of His-Asp phosphorelay signal transduction system 通过His-Asp磷接力信号转导系统的功能在细粒曲霉体内产生活性氧

Mycotoxins Pub Date : 2015-01-31 DOI: 10.2520/MYCO.65.49

K. Kanamaru, Saki Hayashi, Kensuke Kojima, Tetsuo Kobayashi

引用次数: 1

Historical review of researches on yellow rice and mycotoxigenic fungi adherent to rice in Japan 日本黄稻及稻附真菌毒素真菌研究历史回顾

Mycotoxins Pub Date : 2015-01-31 DOI: 10.2520/MYCO.65.19

M. Kushiro

引用次数: 21

Toxicity of trichothecene mycotoxin nivalenol in human leukemia cell line HL60 毛霉烯真菌毒素雪瓦仑醇对人白血病HL60细胞的毒性研究

Mycotoxins Pub Date : 2015-01-31 DOI: 10.2520/MYCO.65.11

H. Nagashima

{"title":"Toxicity of trichothecene mycotoxin nivalenol in human leukemia cell line HL60","authors":"H. Nagashima","doi":"10.2520/MYCO.65.11","DOIUrl":"https://doi.org/10.2520/MYCO.65.11","url":null,"abstract":"The toxicity of nivalenol (NIV) to the human promyelocyte-derived cell line HL60 is reviewed. NIV cytotoxicity was examined after 24 h treatment, and the inhibitor studies were performed. Cells treated with 3 μg/mL or higher NIV were damaged, and more than half of the cells appeared dead. Regarding cell proliferation, the value of 50 % inhibitory concentration of NIV was 0.16 μg/mL. Apparent DNA ladders were observed, showing that NIV induces apoptosis. Concentrations of NIV-caused morphologic damage are in accordance with DNA fragmentation, indicating that marked NIVcaused morphologic change is due to apoptosis. NIV increased interleukin-8 (IL-8/CXCL8) secretion. Conversely, NIV decreased the secretions of other cytokines monocyte chemotactic protein-1 (MCP-1/CCL2), macrophage inflammatory protein-1α (MIP-1α/CCL3), MIP-1β/CCL4, and regulated upon activation, normal T cell expressed and presumably secreted (RANTES/CCL5) concentration-dependently. That intracellular calcium ion chelator BAPTAAM mitigated the cytotoxicity of NIV indicates that this effect is dependent on intracellular calcium ion. The results of an intracellular calcium ion modulator ryanodine receptor (RyR)1-specific inhibitor dantrolene treatment indicates that RyR1 contributes to NIV-induced toxicity. Stress-activated mitogen-activated protein kinases (SAPKs), c-Jun N-terminal kinases (JNKs) and p38s, occupy the crucial positions in NIV-associated retardation of cell proliferation and IL-8 secretion. Transcription factor nuclear factor-κB (NFκB) inhibitors reduced NIV’s effects, indicating that NF-κB is an important factor for exerting NIV toxicity. Regarding cell proliferation, no protective effect of geldanamycin, a molecular chaperone heat shock protein 90 (Hsp90)-specific inhibitor, was observed. Alternatively, Hsp90 appears to play a role in NIV-associated changes in cytokine secretions.","PeriodicalId":19069,"journal":{"name":"Mycotoxins","volume":"61 1","pages":"11-17"},"PeriodicalIF":0.0,"publicationDate":"2015-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84577524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Risk assessment report - Aflatoxin M 1 in milk and aflatoxin B 1 in feeds 风险评估报告-牛奶中的黄曲霉毒素m1和饲料中的黄曲霉毒素b1

Mycotoxins Pub Date : 2015-01-31 DOI: 10.2520/MYCO.65.27

Makoto Oozone

引用次数: 1

Life cycle and infection route of rice false smut fungus in paddy field 稻田稻曲菌的生命周期及侵染途径

Mycotoxins Pub Date : 2015-01-31 DOI: 10.2520/MYCO.65.39

E. Tanaka

引用次数: 1

マイコトキシンとファイトトキシン : 似て非なるもの,あるいは全く同じもの毒素和毒素:似是而非或完全相同的东西

Mycotoxins Pub Date : 2015-01-31 DOI: 10.2520/MYCO.65.57

Motoichiro Kodama, Yasunori Akagi, Kazumi Takao, Takashi Tsuge

引用次数: 1

Mycotoxin contamination of Vietnamese coffee beans caused by Aspergillus sections Nigri and Circumdati 黑曲霉和圆曲霉引起的越南咖啡豆霉菌毒素污染

Mycotoxins Pub Date : 2015-01-31 DOI: 10.2520/MYCO.65.1

R. Hashimoto, H. Nakagawa, Y. Onji, Katsuyoshi Asano, K. Yokoyama, Haruo Takahashi

{"title":"Mycotoxin contamination of Vietnamese coffee beans caused by Aspergillus sections Nigri and Circumdati","authors":"R. Hashimoto, H. Nakagawa, Y. Onji, Katsuyoshi Asano, K. Yokoyama, Haruo Takahashi","doi":"10.2520/MYCO.65.1","DOIUrl":"https://doi.org/10.2520/MYCO.65.1","url":null,"abstract":"Sixteen samples of Vietnamese coffee beans were examined for the presence of mycotoxigenic fungi that produce ochratoxins and fumonisins. Species of the strains isolated from the beans were tentatively identified by morphology as Aspergillus niger species complex (isolation frequencies of the beans: 56.6%), Aspergillus carbonarius (3.3%), and Aspergillus species in section Circumdati (2.9%). The strains randomly selected from the species were correctly identified by sequencing of the β-tubulin and/or mitochondrial cytochrome b gene. All of the strains of A. carbonarius and Aspergillus westerdijkiae, identified in section Circumdati, produced ochratoxin A (OTA). On the other hand, only one out of the 41 strains of A. niger produced a detectable level of OTA. Therefore, A. carbonarius and A. westerdijkiae, rather than A. niger, are likely to be the main sources of OTA contamination in the beans. With regard to A. niger, 37 out of the 41 strains produced fumonsin B2 (FB2). LC-MS/MS analysis of the 16 bean samples showed that 3 samples were contaminated with OTA and/or FB2; one Arabica sample with OTA (2.3 μg/kg), another with FB2 (55 μg/kg), and one Robusta sample with both OTA (6.3 μg/kg) and FB2 (49 μg/kg). These results demonstrate that Vietnamese coffee beans are commonly infected with OTAand FB2-producing fungi and occasionally co-contaminated with these mycotoxins.","PeriodicalId":19069,"journal":{"name":"Mycotoxins","volume":"15 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2015-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74723098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

菌類，主にカビ，と付き合って40年和菌类，主要是霉菌，相处了40年

Mycotoxins Pub Date : 2014-07-31 DOI: 10.2520/MYCO.64.183

賢一河合

引用次数: 0