Molecular Therapy: the Journal of the American Society of Gene Therapy最新文献

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Short-Term Local Expression of a PD-L1 Blocking Antibody from a Self-Replicating RNA Vector Induces Potent Antitumor Responses. 从自我复制的RNA载体短期局部表达PD-L1阻断抗体诱导有效的抗肿瘤反应。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2019-11-01 DOI: 10.1016/j.ymthe.2019.09.016
María Cristina Ballesteros-Briones, E. Martišová, E. Casales, Noelia Silva-Pilipich, M. Buñuales, Javier Galindo, U. Mancheño, M. Gorraiz, J. Lasarte, G. Kochan, D. Escors, A. R. Sánchez-Paulete, I. Melero, J. Prieto, R. Hernández-Alcoceba, S. Hervás-Stubbs, C. Smerdou
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引用次数: 22
Endocytic Profiling of Cancer Cell Models Reveals Critical Factors Influencing LNP-Mediated mRNA Delivery and Protein Expression. 癌细胞模型的内吞分析揭示了影响lnp介导的mRNA传递和蛋白质表达的关键因素。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2019-11-01 DOI: 10.1016/j.ymthe.2019.07.018
E. Sayers, S. Peel, Anna Schantz, Richard M. England, Maya Beano, Stephanie M. Bates, Arpan S. Desai, S. Puri, M. Ashford, A. Jones
{"title":"Endocytic Profiling of Cancer Cell Models Reveals Critical Factors Influencing LNP-Mediated mRNA Delivery and Protein Expression.","authors":"E. Sayers, S. Peel, Anna Schantz, Richard M. England, Maya Beano, Stephanie M. Bates, Arpan S. Desai, S. Puri, M. Ashford, A. Jones","doi":"10.1016/j.ymthe.2019.07.018","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.07.018","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73343946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 52
Micro-utrophin Therapy for Duchenne Muscular Dystrophy. 杜氏肌营养不良的微营养疗法。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2019-10-22 DOI: 10.1016/j.ymthe.2019.10.011
D. Duan
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引用次数: 9
Liver Gene Therapy: Reliable and Durable? 肝脏基因治疗:可靠和持久?
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2019-10-17 DOI: 10.1016/j.ymthe.2019.10.005
R. Herzog, G. Pierce
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引用次数: 21
Immunomodulatory Drugs Encoded by Oncolytic Viruses: Is the Whole Greater Than the Sum? 溶瘤病毒编码的免疫调节药物:整体大于总和吗?
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2019-10-02 DOI: 10.1016/j.ymthe.2019.09.022
D. Zamarin
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引用次数: 0
miR-135b Delivered by Gastric Tumor Exosomes Inhibits FOXO1 Expression in Endothelial Cells and Promotes Angiogenesis. 胃肿瘤外泌体传递的miR-135b抑制内皮细胞中FOXO1的表达并促进血管生成。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2019-10-01 DOI: 10.1016/j.ymthe.2019.06.018
M. Bai, Jialu Li, Haiou Yang, Haiyang Zhang, Zhengyang Zhou, T. Deng, Kegan Zhu, Tao Ning, Q. Fan, G. Ying, Y. Ba
{"title":"miR-135b Delivered by Gastric Tumor Exosomes Inhibits FOXO1 Expression in Endothelial Cells and Promotes Angiogenesis.","authors":"M. Bai, Jialu Li, Haiou Yang, Haiyang Zhang, Zhengyang Zhou, T. Deng, Kegan Zhu, Tao Ning, Q. Fan, G. Ying, Y. Ba","doi":"10.1016/j.ymthe.2019.06.018","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.06.018","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"80 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73037620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 71
Neuromuscular Gene Therapy: Catching the Wave of Positive Early Studies Is Expected to Crest in Product Approvals. 神经肌肉基因疗法:赶上早期积极研究的浪潮,预计产品批准将达到顶峰。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2019-10-01 DOI: 10.1016/j.ymthe.2019.09.011
B. Byrne
{"title":"Neuromuscular Gene Therapy: Catching the Wave of Positive Early Studies Is Expected to Crest in Product Approvals.","authors":"B. Byrne","doi":"10.1016/j.ymthe.2019.09.011","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.09.011","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75530150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Blocking CD30 on T Cells by a Dual Specific CAR for CD30 and Colon Cancer Antigens Improves the CAR T Cell Response against CD30- Tumors. 利用CD30和结肠癌抗原双特异性CAR阻断T细胞上的CD30可提高CAR - T细胞对CD30-肿瘤的反应
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2019-10-01 DOI: 10.1016/J.YMTHE.2019.06.007
A. Hombach, G. Rappl, H. Abken
{"title":"Blocking CD30 on T Cells by a Dual Specific CAR for CD30 and Colon Cancer Antigens Improves the CAR T Cell Response against CD30- Tumors.","authors":"A. Hombach, G. Rappl, H. Abken","doi":"10.1016/J.YMTHE.2019.06.007","DOIUrl":"https://doi.org/10.1016/J.YMTHE.2019.06.007","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81709151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Epigenetically Upregulated MicroRNA-602 Is Involved in a Negative Feedback Loop with FOXK2 in Esophageal Squamous Cell Carcinoma. 表观遗传上调的MicroRNA-602参与食管鳞状细胞癌中FOXK2的负反馈回路
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2019-10-01 DOI: 10.1016/j.ymthe.2019.07.006
Mei-yue Liu, Jia-rui Yu, Dan Wang, Y. Niu, Si-yuan Chen, Peng Gao, Zhao Yang, Huan Wang, Jie Zhang, Chao Zhang, Yue Zhao, Wanning Hu, G. Sun
{"title":"Epigenetically Upregulated MicroRNA-602 Is Involved in a Negative Feedback Loop with FOXK2 in Esophageal Squamous Cell Carcinoma.","authors":"Mei-yue Liu, Jia-rui Yu, Dan Wang, Y. Niu, Si-yuan Chen, Peng Gao, Zhao Yang, Huan Wang, Jie Zhang, Chao Zhang, Yue Zhao, Wanning Hu, G. Sun","doi":"10.1016/j.ymthe.2019.07.006","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.07.006","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79870641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
A Mitochondrial VDAC1-Based Peptide Greatly Suppresses Steatosis and NASH-Associated Pathologies in a Mouse Model. 在小鼠模型中,基于线粒体vdac1的肽极大地抑制脂肪变性和nash相关病理。
Molecular Therapy: the Journal of the American Society of Gene Therapy Pub Date : 2019-10-01 DOI: 10.1016/j.ymthe.2019.06.017
Srinivas Pittala, Y. Krelin, Y. Kuperman, V. Shoshan-Barmatz
{"title":"A Mitochondrial VDAC1-Based Peptide Greatly Suppresses Steatosis and NASH-Associated Pathologies in a Mouse Model.","authors":"Srinivas Pittala, Y. Krelin, Y. Kuperman, V. Shoshan-Barmatz","doi":"10.1016/j.ymthe.2019.06.017","DOIUrl":"https://doi.org/10.1016/j.ymthe.2019.06.017","url":null,"abstract":"","PeriodicalId":19039,"journal":{"name":"Molecular Therapy: the Journal of the American Society of Gene Therapy","volume":"140 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77741457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
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