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Molecular Therapy最新文献

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TNFAIP8L2 as a dual regulator of mTORC1 signaling: Implications for therapy in presbycusis. TNFAIP8L2作为mTORC1信号的双重调节因子：对老年性痴呆的治疗意义。
IF 12.4 1区 医学
Molecular Therapy Pub Date : 2025-06-24 DOI: 10.1016/j.ymthe.2025.06.008
Yanfei Wang,Xinmiao Fan,Liheng Li,Qing Yin Zheng
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引用次数: 0
Improved SARS-CoV-2 vaccine based on intranasally administered replicon RNA. 基于鼻内给药复制子RNA的改进SARS-CoV-2疫苗
IF 12.4 1区 医学
Molecular Therapy Pub Date : 2025-06-24 DOI: 10.1016/j.ymthe.2025.06.016
Kenneth Lundstrom
{"title":"Improved SARS-CoV-2 vaccine based on intranasally administered replicon RNA.","authors":"Kenneth Lundstrom","doi":"10.1016/j.ymthe.2025.06.016","DOIUrl":"https://doi.org/10.1016/j.ymthe.2025.06.016","url":null,"abstract":"","PeriodicalId":19020,"journal":{"name":"Molecular Therapy","volume":"21 1","pages":""},"PeriodicalIF":12.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extrachromosomal DNA maintenance and DNA damage response: A bidirectional axis in cancer progression and therapy. 染色体外DNA维持和DNA损伤反应：癌症进展和治疗的双向轴。
IF 12.4 1区 医学
Molecular Therapy Pub Date : 2025-06-24 DOI: 10.1016/j.ymthe.2025.06.013
Yang Meng,Zijun Feng,Junhong Han
{"title":"Extrachromosomal DNA maintenance and DNA damage response: A bidirectional axis in cancer progression and therapy.","authors":"Yang Meng,Zijun Feng,Junhong Han","doi":"10.1016/j.ymthe.2025.06.013","DOIUrl":"https://doi.org/10.1016/j.ymthe.2025.06.013","url":null,"abstract":"","PeriodicalId":19020,"journal":{"name":"Molecular Therapy","volume":"235 1","pages":""},"PeriodicalIF":12.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Harnessing engineered NK cells for refractory CD30+ lymphoma. 利用工程NK细胞治疗难治性CD30+淋巴瘤。
IF 12.4 1区 医学
Molecular Therapy Pub Date : 2025-06-24 DOI: 10.1016/j.ymthe.2025.06.001
Yago Nieto,Katayoun Rezvani
{"title":"Harnessing engineered NK cells for refractory CD30+ lymphoma.","authors":"Yago Nieto,Katayoun Rezvani","doi":"10.1016/j.ymthe.2025.06.001","DOIUrl":"https://doi.org/10.1016/j.ymthe.2025.06.001","url":null,"abstract":"","PeriodicalId":19020,"journal":{"name":"Molecular Therapy","volume":"17 1","pages":""},"PeriodicalIF":12.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Double trouble: Non-relapse mortality with bispecific antibodies in lymphoma and myeloma. 双重困扰：淋巴瘤和骨髓瘤双特异性抗体的非复发死亡率。
IF 12.4 1区 医学
Molecular Therapy Pub Date : 2025-06-24 DOI: 10.1016/j.ymthe.2025.06.014
Rahul Banerjee,Samuel Yamshon
{"title":"Double trouble: Non-relapse mortality with bispecific antibodies in lymphoma and myeloma.","authors":"Rahul Banerjee,Samuel Yamshon","doi":"10.1016/j.ymthe.2025.06.014","DOIUrl":"https://doi.org/10.1016/j.ymthe.2025.06.014","url":null,"abstract":"","PeriodicalId":19020,"journal":{"name":"Molecular Therapy","volume":"55 1","pages":""},"PeriodicalIF":12.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond the bench: Revitalizing ataluren development for rare genetic disorders 超越替补席：重振罕见遗传疾病的人才发展
IF 12.4 1区 医学
Molecular Therapy Pub Date : 2025-06-21 DOI: 10.1016/j.ymthe.2025.06.002
Valentino Bezzerri, Marco Cipolli
{"title":"Beyond the bench: Revitalizing ataluren development for rare genetic disorders","authors":"Valentino Bezzerri, Marco Cipolli","doi":"10.1016/j.ymthe.2025.06.002","DOIUrl":"https://doi.org/10.1016/j.ymthe.2025.06.002","url":null,"abstract":"","PeriodicalId":19020,"journal":{"name":"Molecular Therapy","volume":"70 1","pages":""},"PeriodicalIF":12.4,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel AAV-based GJB2 gene therapy restores hearing function 新的基于aav的GJB2基因治疗恢复听力功能
IF 12.4 1区 医学
Molecular Therapy Pub Date : 2025-06-21 DOI: 10.1016/j.ymthe.2025.06.006
Lukas D. Landegger
{"title":"Novel AAV-based GJB2 gene therapy restores hearing function","authors":"Lukas D. Landegger","doi":"10.1016/j.ymthe.2025.06.006","DOIUrl":"https://doi.org/10.1016/j.ymthe.2025.06.006","url":null,"abstract":"","PeriodicalId":19020,"journal":{"name":"Molecular Therapy","volume":"45 1","pages":""},"PeriodicalIF":12.4,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeting EBV gp42 for nasopharyngeal carcinoma prevention 靶向EBV gp42预防鼻咽癌
IF 12.4 1区 医学
Molecular Therapy Pub Date : 2025-06-21 DOI: 10.1016/j.ymthe.2025.06.005
Cong Sun, Le-Le Zhang, Mu-Sheng Zeng
{"title":"Targeting EBV gp42 for nasopharyngeal carcinoma prevention","authors":"Cong Sun, Le-Le Zhang, Mu-Sheng Zeng","doi":"10.1016/j.ymthe.2025.06.005","DOIUrl":"https://doi.org/10.1016/j.ymthe.2025.06.005","url":null,"abstract":"","PeriodicalId":19020,"journal":{"name":"Molecular Therapy","volume":"32 1","pages":""},"PeriodicalIF":12.4,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Harnessing B19-directed CAR T cells for AAV vector administration in seropositive patients: The importance of the niche 利用b19导向的CAR - T细胞在血清阳性患者中进行AAV载体管理：生态位的重要性
IF 12.4 1区 医学
Molecular Therapy Pub Date : 2025-06-21 DOI: 10.1016/j.ymthe.2025.06.007
Hanadi Saliba, David Alexandre Gross, Giuseppe Ronzitti
{"title":"Harnessing B19-directed CAR T cells for AAV vector administration in seropositive patients: The importance of the niche","authors":"Hanadi Saliba, David Alexandre Gross, Giuseppe Ronzitti","doi":"10.1016/j.ymthe.2025.06.007","DOIUrl":"https://doi.org/10.1016/j.ymthe.2025.06.007","url":null,"abstract":"","PeriodicalId":19020,"journal":{"name":"Molecular Therapy","volume":"47 1","pages":""},"PeriodicalIF":12.4,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bispecific receptor decoys: A new player to a crowded field 双特异性受体诱饵：一个进入拥挤区域的新玩家
IF 12.4 1区 医学
Molecular Therapy Pub Date : 2025-06-21 DOI: 10.1016/j.ymthe.2025.06.015
Glenn Yiu
{"title":"Bispecific receptor decoys: A new player to a crowded field","authors":"Glenn Yiu","doi":"10.1016/j.ymthe.2025.06.015","DOIUrl":"https://doi.org/10.1016/j.ymthe.2025.06.015","url":null,"abstract":"","PeriodicalId":19020,"journal":{"name":"Molecular Therapy","volume":"3 1","pages":""},"PeriodicalIF":12.4,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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