The Clinical Respiratory Journal最新文献

{"title":"The relationship between absolute counts of lymphocyte subsets and clinical features in patients with pulmonary tuberculosis","authors":"Hui-ru An, X. Bai, Jian-qin Liang, Tao Wang, Zhong-Yuan Wang, Y. Xue, Yinping Liu, Lan Wang, Xueling Wu","doi":"10.1111/crj.13490","DOIUrl":"https://doi.org/10.1111/crj.13490","url":null,"abstract":"The aim of the present study is to investigate the clinical value and characteristics of peripheral blood lymphocyte subsets in patients with pulmonary tuberculosis (PTB) using flow cytometry.","PeriodicalId":187910,"journal":{"name":"The Clinical Respiratory Journal","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"118010232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative intervention with long‐acting bronchodilators for the reduction of postoperative pulmonary complications in untreated patients with obstructive lung disease","authors":"Yu Mikami, T. Jo, H. Matsuzaki, Taro Ishimori, Minako Saito, Y. Sakamoto, Y. Yamauchi, D. Takai, Y. Yatomi, T. Nagase","doi":"10.1111/crj.13105","DOIUrl":"https://doi.org/10.1111/crj.13105","url":null,"abstract":"Obstructive lung disease (OLD) is a risk factor for postoperative pulmonary complications (PPC) and is incidentally discovered during preoperative evaluation. The key treatments for OLD are inhaled long‐acting bronchodilators (LAB). However, the advantage of preoperative bronchodilator treatment for patients with OLD remains unclear. The aim of this study is to elucidate the effect of preoperative LAB treatment in patients with untreated OLD on postoperative outcomes.","PeriodicalId":187910,"journal":{"name":"The Clinical Respiratory Journal","volume":"17 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117562029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular identification and distribution of non‐tuberculous mycobacteria isolated from clinical specimens by PCR‐sequencing method in West of Iran","authors":"Mahsa Dastranj, A. Farahani, Abdolrazagh Hashemi Shahraki, S. Atashi, P. Mohajeri","doi":"10.1111/crj.12617","DOIUrl":"https://doi.org/10.1111/crj.12617","url":null,"abstract":"Infections by non‐tuberculous mycobacteria (NTM) has rapidly increased in recent years, due to high infection rates related to the populations at risk like immunocompromised individuals, patients predisposed by prior pulmonary. The aim of this study was to investigate the presence of NTM in clinical samples and genetic diversity using 16S rRNA and rpoB sequence analysis.","PeriodicalId":187910,"journal":{"name":"The Clinical Respiratory Journal","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120506281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is the electrocardiogram still useful in detecting right ventricular abnormalities in patients with pulmonary hypertension when compared to echocardiography?","authors":"Alfredo Lamela Domenech, A. López-Candales","doi":"10.1111/crj.12607","DOIUrl":"https://doi.org/10.1111/crj.12607","url":null,"abstract":"In pulmonary hypertension (PH), unopposed increases in pulmonary vascular resistance will trigger right ventricular (RV) structural and functional remodeling changes that could result in RV failure, the main cause of death in patients with PH. While transthoracic echocardiography (TTE) is a widely recognized noninvasive imaging tool in the evaluation of RV abnormalities in PH; the electrocardiogram (ECG) though still obtained as part of initial PH workup suffers from limitations in sensitivity (55%) and specificity (70%). However, recent cardiac magnetic resonance data suggests that ECGs might still be useful to detect changes in RV load. Consequently, we queried our database and found a heterogeneous group of 85 patients with PH who had both ECG and TTE to determine whether any of the common ECG abnormalities known to occur in PH such as resting tachycardia, changes in the amplitude of R and S waves in precordial lead V1, and frontal axis deviation 110 degrees was useful in identifying any significant RV structural or functional abnormalities by echocardiography. The University of Cincinnati IRB approved this study. All TTE examinations were performed according to published guidelines and measurements were compared using two-tailed unpaired t-test assuming unequal variances. ECGs were read by two independent readers (Inter-rater agreement: Kappa static5 0.86 and 95% confidence interval) blinded to TTE results. P-values of less than .05 were considered to be statistically significant. All statistics were calculated in MedCalc Software bvba Version 14.12.0 (Belgium). In the population studied, patients with sinus tachycardia had significantly higher pulmonary artery systolic pressures. In the case of right axis deviation, not only patients were younger but also had higher pulmonary artery systolic pressures with worse RV systolic function. Finally, no RV echocardiographic abnormalities were abnormal with an rsR’ pattern in lead V1. The results of this small comparative study once again fail to show any significant correlation between ECG and RV abnormalities when assessed by TTE. However, before we completely discredit the utility of ECGs to assess PH patients it is important to highlight data from recent studies in both rats and humans showing that even a mild increase in RV pressure load is associated with substantial changes in myocardial electrical properties, detectable in a standard ECG recording when three-dimensional echocardiography or cardiac magnetic resonance imaging are used. Furthermore, some ECG abnormalities are known to occur more commonly in specific subgroups of PH patients. More specifically, right bundle branch block is an independent predictor of mortality in patients with systemic sclerosis while conduction abnormalities not only are common in patients with chronic obstructive pulmonary disease, but also these ECG abnormalities increase with disease severity. In conclusion, the jury is still regarding the potential value for","PeriodicalId":187910,"journal":{"name":"The Clinical Respiratory Journal","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"118805043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When the bronchoalveolar lavage makes the diagnosis of interstitial pneumonia","authors":"M. Mlika, Meriem Triki, H. Kwas, E. Braham, H. Ghédira, F. Mezni","doi":"10.1111/crj.12464","DOIUrl":"https://doi.org/10.1111/crj.12464","url":null,"abstract":"A 30-year-old non-smoker woman without a particular past medical history consulted for dyspnoea and non-productive cough. Chest CT scan revealed mediastinal and hilar adenopathies associated with bilateral ground glass opacities with thickened interlobular septa. Bronchoalveolar lavage was performed (Fig. 1). The fluid was opaque with a milky turbid gross appearance. On microscopic examination, finely granular amorphous material was apparent in the background along with numerous lymphocytes and fragmented macrophages. Zhiel stain was performed but was negative. The diagnosis of pulmonary alveolar proteinosis (PAP) was suspected but the association of mediastinal adenomegalies was not concordant with the diagnosis. Surgical biopsy of the lung and the mediastinal lymph nodes was performed. Histological examination revealed granulomatous inflammation with caseous necrosis in the lymph nodes and an amorphous PAS positif lipoprotein material filling the alveolar spaces in the lung (Fig. 2). The final diagnosis of associated PAP with tuberculosis infection was established. The patient was put on anti-tuberculosis drugs and presented an improvement of her general state.","PeriodicalId":187910,"journal":{"name":"The Clinical Respiratory Journal","volume":"30 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120164418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interventional therapy in sarcoidosis‐associated pulmonary arterial stenosis and pulmonary hypertension","authors":"Lingli Liu, Jian Xu, Yuhai Zhang, Liying Fang, Yaqin Chai, Meng-jie Niu, Shengqing Li","doi":"10.1111/crj.12435","DOIUrl":"https://doi.org/10.1111/crj.12435","url":null,"abstract":"Pulmonary sarcoidosis is often complicated by pulmonary hypertension, a complication that is associated with increased disability and mortality. To this point, however, little progress has been made in the treatment of sarcoidosis associated with pulmonary hypertension (SAPH).","PeriodicalId":187910,"journal":{"name":"The Clinical Respiratory Journal","volume":"129 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"119715532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long time enzyme replacement therapy stabilizes obstructive lung disease and alters peripheral immune cell subsets in Fabry patients","authors":"B. Odler, Á. Cseh, T. Constantin, G. Fekete, G. Losonczy, L. Tamási, K. Benke, B. Szilveszter, V. Müller","doi":"10.1111/crj.12446","DOIUrl":"https://doi.org/10.1111/crj.12446","url":null,"abstract":"Fabry disease is an X‐linked lysosomal storage disorder, causing accumulation of globotriaosylceramid in different organs. Glycolipids are activators of different immune cell subsets the resulting inflammation is responsible for organ damage. Pulmonary involvement leads to airway inflammation; however, data on severity, as well as the effect of enzyme replacement therapy on lung function parameters and changes in peripheral immune cell subsets on lung involvement are sparse.","PeriodicalId":187910,"journal":{"name":"The Clinical Respiratory Journal","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"119361214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atopy: a risk factor of refractory mycoplasma pneumoniae pneumonia?","authors":"Y. Bao, Jing Li, Ye Tian, Q. Liu, Jun Bao","doi":"10.1111/crj.12439","DOIUrl":"https://doi.org/10.1111/crj.12439","url":null,"abstract":"To investigate the relationship of pathogen DNA copies with clinic and laboratory features among children with Mycoplasma pneumoniae (MP) pneumonia.","PeriodicalId":187910,"journal":{"name":"The Clinical Respiratory Journal","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"118219130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arm strength training improves activities of daily living and occupational performance in patients with COPD","authors":"E. Calik-Kutukcu, H. Arikan, M. Sağlam, N. Vardar-Yagli, C. Oksuz, D. Inal-Ince, S. Savcı, T. Duger, L. Coplu","doi":"10.1111/crj.12422","DOIUrl":"https://doi.org/10.1111/crj.12422","url":null,"abstract":"Arm strength training may improve functional performance for patients with chronic obstructive pulmonary disease (COPD). This trial investigated the effects of arm strength training on arm exercise capacity, activities of daily living (ADL) and occupational performance in patients with COPD.","PeriodicalId":187910,"journal":{"name":"The Clinical Respiratory Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"119351625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory markers and circulating extracellular matrix proteins in patients with chronic obstructive pulmonary disease and left ventricular diastolic dysfunction","authors":"M. López‐Sánchez, M. Muñoz-Esquerre, Daniel Huertas, A. Montes, M. Molina-Molina, F. Manresa, J. Dorca, S. Santos","doi":"10.1111/crj.12428","DOIUrl":"https://doi.org/10.1111/crj.12428","url":null,"abstract":"Left ventricular diastolic dysfunction (LVDD) is a frequent condition in chronic obstructive pulmonary disease (COPD). Tenascin‐C (Tn‐C) and matrix metalloproteinase‐9 (MMP‐9) are extracellular matrix proteins associated with myocardial fibrosis and wall remodeling because of inflammation.","PeriodicalId":187910,"journal":{"name":"The Clinical Respiratory Journal","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"119068399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}