Minerva gastroenterology最新文献

{"title":"Gastro-esophageal reflux, laryngo-pharyngeal reflux symptoms, and dysphonia in the Italian population of the area of Milan: results of an internet survey.","authors":"Francesco Mozzanica, Carlo Robotti, Federico Ambrogi, Giulia Bertino, Marco Benazzo, Fabio Pace, Antonio Schindler","doi":"10.23736/S2724-5985.23.03380-6","DOIUrl":"10.23736/S2724-5985.23.03380-6","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"472-474"},"PeriodicalIF":3.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9242755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cystic tumor ablation with different concentrations of lauromacrogol solution in an animal model.","authors":"Fei Gao, Huikai Li, Xiuxue Feng, Chen DU, Ke Han, Ningli Chai, Enqiang Linghu","doi":"10.23736/S2724-5985.23.03486-1","DOIUrl":"10.23736/S2724-5985.23.03486-1","url":null,"abstract":"<p><strong>Background: </strong>Lauromacrogol, as a sclerosing agent, can induce aseptic inflammation and fibrous tissue proliferation to achieve sclerotherapy. Lauromacrogol is widely used not only for vascular sclerotherapy but also for the treatment of different cystic tumors. To evaluate the efficacy and safety of cystic tumor ablation with different concentrations of lauromacrogol solution in a rat endometriosis model, and explore the advantages and disadvantages of this model in simulating pancreatic cystic neoplasm.</p><p><strong>Methods: </strong>An endometriotic cyst model was established in 50 mature female Sprague-Dawley rats. After 4 weeks, successfully modeled cysts were randomly divided into four groups: group A, in which cyst were injected with normal saline; and groups B to D, in which cyst were injected with 1%, 2%, and 3% lauromacrogol solution, respectively. The rats were then fed for 4 more weeks. The abdominal cavity was opened to observe the morphology of the cyst and the degree of damage to surrounding organs. If the ablation procedure failed, the whole cyst was collected; if the ablation procedure was successful, residual scar tissue was collected. The ratio of ablated epithelial cells to the epithelial layer and the intactness of the lamina propria were observed by low- and high-power microscopy.</p><p><strong>Results: </strong>After ablation, the cysts in normal saline group showed a maintained hemispherical structure, whereas those in three different concentrations of lauromacrogol solution groups showed a flat scar. The effective rate of each group was statistically different. Pairwise comparison of corrected significance levels using the Bonferroni method showed statistically a significant difference between normal saline group and 1% lauromacrogol solution group, 2% lauromacrogol solution group and 3% lauromacrogol solution group.</p><p><strong>Conclusions: </strong>According to the morphology and pathology of rat endometriotic cysts after ablation, it can be preliminarily concluded that ablation with 1%, 2%, or 3% lauromacrogol solution is an effective and safe therapeutic option. Rat endometriotic cyst model can simulate pancreatic cystic neoplasms to a certain extent.</p>","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"422-429"},"PeriodicalIF":3.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10161754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of comprehensive evaluation methods in quality control of nursing care in gastrointestinal endoscopy operating rooms.","authors":"Yibing Hu, Haoliang Yu, Xiaoli Jin, Tingting Zhu","doi":"10.23736/S2724-5985.23.03522-2","DOIUrl":"10.23736/S2724-5985.23.03522-2","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"474-475"},"PeriodicalIF":3.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9927788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eye involvement in patient with gastric reflux: an intriguing contingency.","authors":"Valerio Damiani, Giorgio Ciprandi","doi":"10.23736/S2724-5985.23.03509-X","DOIUrl":"10.23736/S2724-5985.23.03509-X","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"470-472"},"PeriodicalIF":3.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9929923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prebiotics targeting gut-liver axis to treat non-alcoholic fatty liver disease.","authors":"Gabriele Castelnuovo, Nuria Perez-Diaz-Del-Campo, Marta Guariglia, Irene Poggiolini, Angelo Armandi, Chiara Rosso, Gian P Caviglia, Elisabetta Bugianesi","doi":"10.23736/S2724-5985.23.03361-2","DOIUrl":"10.23736/S2724-5985.23.03361-2","url":null,"abstract":"<p><p>Non-alcoholic steatohepatitis (NASH) is a high-prevalence, rapidly growing form of non-alcoholic fatty liver disease (NAFLD), which is closely linked to obesity and metabolic disorders. Gut microbiota has been increasingly recognized as a key factor in the onset of NAFLD in recent years. The liver can be strongly influenced by changes in the gut microbiota through the portal vein, giving the gut-liver axis a very important role in understanding the pathophysiology of liver diseases. A healthy intestinal barrier is characterized by selective permeability to nutrients, metabolites, water and bacterial products and its impairment may be a predisposing or aggravating condition for the progression of NAFLD. In most cases, NAFLD patients follow a Western diet pattern, which is closely linked to obesity and associated metabolic diseases, promoting inflammation, structural and behavioral changes in the gut microbiota. In fact, factors such as age, gender, genetic or environmental factors may induce a dysbiotic microbiota that promotes epithelial barrier dysfunction and increased intestinal permeability, favoring the progression of NAFLD. In this context, new dietary approaches, such as prebiotics, are emerging to prevent disease and maintain health. In this review, we reported the role of the gut-liver axis in the pathogenesis of NAFLD and investigated the potential therapeutic effect of prebiotics on the enhancement of intestinal barrier dysfunction, hepatic steatosis and, consequently, the progression of NAFLD.</p>","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"446-453"},"PeriodicalIF":3.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9077527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-related quality of life in patients with primary biliary cholangitis: a cross-sectional study from a single centre in Denmark.","authors":"Patricia A Skat-Rørdam, Johanna Eliasson, Mette Skalshøi Kjær, Palle Bekker Jeppesen, Henriette Ytting","doi":"10.23736/S2724-5985.23.03206-0","DOIUrl":"10.23736/S2724-5985.23.03206-0","url":null,"abstract":"<p><strong>Background: </strong>The impact of primary biliary cholangitis (PBC) on health-related quality of life (HRQOL) is poorly understood. The aim of this study was to compare HRQOL in Danish patients with PBC to the general population and to assess associations to clinical and laboratory data.</p><p><strong>Methods: </strong>We conducted a single-centre, cross-sectional questionnaire study in patients with PBC using the SF-36 and EQ-5D-5L. Clinical and paraclinical data were obtained from patients' healthcare records. SF-36 scores were compared to an age- and gender-matched Danish general population. A general linear model was used to explore which variables were associated with main SF-36 scores.</p><p><strong>Results: </strong>Sixty-nine patients with PBC were included. Compared to the Danish general population, patients with PBC had a significantly lower HRQOL in the domains bodily pain, general health, vitality, social functioning, mental health and mental component summary score. No clinical characteristics (gender, age at inclusion, concurrent autoimmune hepatitis, pruritus or cirrhosis) or biochemical markers were significantly associated with main SF-36 scores (physical and mental component summary).</p><p><strong>Conclusions: </strong>The study is the first to report on HRQOL in a well-characterized PBC patient population from Denmark. Danish patients with PBC had a significantly impaired HRQOL compared to the general population with the greatest impairment in mental aspects. Reductions in HRQOL were independent of clinical characteristics and biochemical markers why HRQOL should be considered as an independent outcome.</p>","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"281-290"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9639131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serrated polyps <10 mm cannot reliably be characterized by i-Scan without magnification at routine colonoscopy.","authors":"Sabrina Gg Testoni, Chiara Notaristefano, Giuliano F Bonura, Maria Napolitano, Dario Esposito, Edi Viale, Lorella Fanti, Francesco Azzolini, Giulia M Cavestro, PierAlberto Testoni","doi":"10.23736/S2724-5985.23.03420-4","DOIUrl":"10.23736/S2724-5985.23.03420-4","url":null,"abstract":"<p><strong>Background: </strong>Colorectal lesions (CRLs) <10 mm found at colonoscopy tend towards \"diagnose-and-leave\" or \"resect-and-discard\" strategies based on real-time Kudo glandular pit-pattern's assessment using i-Scan. However, i-Scan has not yet been validated for Kudo's classification. We aimed to assess whether, in routine colonoscopy, i-Scan without magnification and optical enhancement (M-OE) reliably differentiates hyperplastic polyps (HPs) from other serrated lesions (SLs) and conventional adenomas (CAs), and, among SLs, HPs from sessile serrated lesions (SSLs) and traditional or unknown serrated adenomas (TSAs, USAs), in Kudo type II CRLs<10 mm, according to ASGE Preservation and Incorporation of Valuable endoscopic Innovations (PIVI) recommended negative predictive value (NPV) threshold for adenomas.</p><p><strong>Methods: </strong>Prospectively recorded CRLs over 12 months, classified according to Kudo pit-pattern using i-Scan, were retrospectively compared with histology.</p><p><strong>Results: </strong>Overall, 898 ≤5-mm and 704 6- to 9-mm CRLs were included. Type II pit-pattern was found in 76.6% and 38.7% of HPs and SSLs-TSAs/CAs (P<0.000001), and in 84.1% and 26.6% of SLs and CAs (P<0.000001). Among SLs, it was found in 81.9% and 86.6% of HPs and SSLs-TSAs. In CRLs≤5 mm, HPs were prevalent over other SLs (P=0.00001); in CRLs 6-9 mm, CAs were prevalent (P<0.000001). About 77% of SLs in right colon were SSLs-TSAs; 82% in left colon were HPs. PIVI ≥90% NPV threshold for adenomas was reached for CRLs 6-9mm (92.1%), nearly achieved for CRLs≤5 mm (88.2%), and not reached for SLs independently on the size.</p><p><strong>Conclusions: </strong>A strategy of \"diagnose-and-leave\" or \"resect-and-discard\" cannot be recommended for SLs<10 mm with Kudo type II pit-pattern using i-Scan, especially in right colon, if M-OE unavailable.</p>","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"306-314"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9699628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of prognostic factors and model establishment of long-term postoperative effect in children with hepatoblastoma.","authors":"Junjie Lin, Yuanqi Wang, Shiming Shi, Wenzong Gao, Juntao Xie, Juncheng Liu, Hong Jiang, Li Zhou","doi":"10.23736/S2724-5985.23.03462-9","DOIUrl":"10.23736/S2724-5985.23.03462-9","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"378-381"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9639134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of comprehensive nursing intervention on the psychological status and quality of life of patients with severe acute myeloid leukemia.","authors":"Mengtian Zong, Wei Chen","doi":"10.23736/S2724-5985.23.03417-4","DOIUrl":"10.23736/S2724-5985.23.03417-4","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"374-376"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9439009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brunner's gland hamartoma misdiagnosed as a case of duodenal malignancy.","authors":"Zhe Wang, Xiaoming Zhu, Zhenying Yue, Jun Lu, Guozheng Pan, Faping You","doi":"10.23736/S2724-5985.23.03524-6","DOIUrl":"10.23736/S2724-5985.23.03524-6","url":null,"abstract":"","PeriodicalId":18653,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"386-387"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10610492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}