Medicinski pregled最新文献_第2页

[Hemilaryngectomy].

Medicinski pregled Pub Date : 2020-02-07 DOI: 10.32388/1rldyh

D. Balenović, V. Odavic

引用次数: 2

[Sudden cardiac death]. [心脏性猝死]。

Medicinski pregled Pub Date : 2020-02-07 DOI: 10.32388/y2mapl

V. Topalov, B. Radišić, D. Kovacević

引用次数: 1

Genetic analysis of multiple primary cancers: A case report 多发原发肿瘤的遗传分析1例

Medicinski pregled Pub Date : 2020-01-01 DOI: 10.2298/mpns2006170j

M. Jevrić, E. Filipović, A. Krivokuca

{"title":"Genetic analysis of multiple primary cancers: A case report","authors":"M. Jevrić, E. Filipović, A. Krivokuca","doi":"10.2298/mpns2006170j","DOIUrl":"https://doi.org/10.2298/mpns2006170j","url":null,"abstract":"Introduction. The occurrence of more than one primary cancer in the same patient is not very common. Multiple cancer prevalence is about 7.9% and the percentage is lower as the number of multiple primary cancers is higher. The incidence of four or more primary cancers in one patient is very rare and its prevalence is around 0.07%. Case Report. We report a rare case of a female with four histopathologically confirmed primary malignant neoplasms. The first tumor was endometrial carcinoma diagnosed at the age of 52. Three additional metachronous tumors were diagnosed as follows: left breast cancer, melanoma, and contralateral breast cancer. Extensive genetic testing was performed and 19 genes were sequenced using the next generation sequencing (BRCA1, BRCA2, ATM, BRIP1, CDH1, CHEK2, MSH2, MLH1, MSH6, PMS2, EPCAM, NBN, NF1, PALB2, PTEN, RAD51C, RAD51D, STK11 and TP53). Even with the existing indicators of genetic etiology, this case showed no pathogenic mutations in any of these genes. This indicates the existence of other underlying mechanisms such as hormonal factors, previous treatment of the primary and subsequent tumors, environmental factors, gene-gene and gene-environment interactions, as well as immunosuppression that could increase the risk for the second and subsequent malignancies. Conclusion. Detailed information on the biology of multiple primary tumors is important for both clinicians and cancer patients during medical management following primary treatment. In addition, genetic information is very important because it has future implications for both patients and their family members.","PeriodicalId":18511,"journal":{"name":"Medicinski pregled","volume":"53 1","pages":"170-174"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75187893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The outcomes of triplet pregnancies 三胞胎妊娠的结果

Medicinski pregled Pub Date : 2020-01-01 DOI: 10.2298/mpns2006153k

A. Krsman, Branislava Baturan, D. Petrovic, D. Ilić, B. Gutic, D. Panic

{"title":"The outcomes of triplet pregnancies","authors":"A. Krsman, Branislava Baturan, D. Petrovic, D. Ilić, B. Gutic, D. Panic","doi":"10.2298/mpns2006153k","DOIUrl":"https://doi.org/10.2298/mpns2006153k","url":null,"abstract":"Introduction. Extensive use of assisted reproduction has resulted in an increased incidence of triplet pregnancies, which are associated with higher risk of complications in mothers and newborns. Material and Methods. A retrospective study reviewed a total of 85 triplet pregnancies delivered at the Department of Obstetrics and Gynecology, Clinical Center of Vojvodina, Novi Sad, from January 1, 2010 to December 31, 2017. Results. The average maternal age was 32 years and the average body mass index was 30.56 kg/m2. The average gestational age at birth was 32 weeks. One patient (1.18%) had vaginal delivery, while 84 (98.82%) pregnancies were completed by cesarean section. The average blood loss was 1294 ml and there was one postpartum hysterectomy. The most common maternal pregnancy-induced complications were sideropenic anemia (70.58%), hypertensive syndrome (40%) and obstetric cholestasis (35.29%). Preterm premature rupture of membranes was observed in 17 (20%) patients. Prophylactic cerclage was performed in 57 patients (67.05%) and 12 patients (14.11%) received tocolytic therapy. The average birth weight of the first newborn was 1838 g, 1755 g of the second, and 1695 g of the third. Body weight ? 1500 g was observed in 61 newborns (24.01%). The mean Apgar score in the first minute was 7, while in the fifth minute it was 8. Respiratory distress syndrome was found in 64 newborns (25.19%). Conclusion. Monitoring and treatment of triplet pregnancies remains a complex task for obstetricians due to the increased incidence of prematurity and perinatal morbidity.","PeriodicalId":18511,"journal":{"name":"Medicinski pregled","volume":"200 1","pages":"153-157"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80120146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare case of adrenal cavernous hemangioma 肾上腺海绵状血管瘤1例

Medicinski pregled Pub Date : 2020-01-01 DOI: 10.2298/mpns2004101v

Ivo Vujicik

{"title":"A rare case of adrenal cavernous hemangioma","authors":"Ivo Vujicik","doi":"10.2298/mpns2004101v","DOIUrl":"https://doi.org/10.2298/mpns2004101v","url":null,"abstract":"Introduction. Adrenal cavernous hemangiomas are extremely rare non-functioning benign tumors. The majority of adrenal cavernous hemangiomas are diagnosed incidentally after surgery by histopathological examination. Case Report. We report a clinical case of a 57-year-old woman with adrenal cavernous hemangioma. On admission, the patient?s adrenal-related hormones were in the reference range, so adrenal endocrine dysfunction was ruled out. The computed tomography scan revealed a well-circumscribed, round, heterogeneous right adrenal mass (32.3 x 55.4 mm). Iodinated contrast enhanced abdominal computed tomography showed a slight inhomogeneity. In this case, preoperative radiologic findings and absence of signs of local invasion indicated laparoscopic adrenalectomy. The patient underwent right transperitoneal adrenalectomy. Microscopic evaluation showed a sinusoidal dilatation and fibrotic septa, so postoperative diagnosis of adrenal cavernous hemangioma was made. Conclusion. In summary, we reported a case of an incidentally discovered non-functioning adrenal cavernous hemangioma treated by laparoscopic surgery. The diagnosis of adrenal cavernous hemangioma may be challenging, and it is commonly made after surgery, since it is frequently confirmed by histopathological examination.","PeriodicalId":18511,"journal":{"name":"Medicinski pregled","volume":"28 1","pages":"101-103"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81447092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of rotator cuff tears 肩袖撕裂的治疗

Medicinski pregled Pub Date : 2020-01-01 DOI: 10.2298/mpns2004077n

S. Ninkovic

引用次数: 0

Transcranial doppler methods in the assessment of cerebral vasomotor reactivity 经颅多普勒法评价脑血管舒缩反应性

Medicinski pregled Pub Date : 2020-01-01 DOI: 10.2298/mpns2002021l

Aleksandra Lučić-Prokin, P. Slankamenac, P. Kovačević

{"title":"Transcranial doppler methods in the assessment of cerebral vasomotor reactivity","authors":"Aleksandra Lučić-Prokin, P. Slankamenac, P. Kovačević","doi":"10.2298/mpns2002021l","DOIUrl":"https://doi.org/10.2298/mpns2002021l","url":null,"abstract":"Introduction. Transcranial Doppler is the only non-invasive neuroimaging modality in the diagnosis and monitoring of various neurovascular diseases. Apart from assessing cerebral hemodynamics of blood flow in the basal brain arteries, transcranial Doppler provides physiological data and anatomical images. Quantification analysis of vasomotor reactivity. Various transcranial Doppler methods evaluate cerebral vasomotor reactivity, providing important information on the properties of arterioles under induced hemodynamic conditions. Exogenous and endogenous vasoactive stimuli of different potency (apnea, acetazolamide, carbon dioxide, L-arginine) are most commonly used, making transcranial Doppler a prognostic indicator of future ischemic events. This article reviews principles of various transcranial Doppler methods in the evaluation of vasomotor reactivity, emphasizing their advantages and disadvantages. Transcranial Doppler in the field of reduced vasomotor reactivity. Evaluation of vasomotor reactivity has a role in the prediction of future ischemic events, evaluation of revascularization effect after carotid endarterectomy, but also in the increasingly significant choice of the right time to perform it. In recent years, transcranial Doppler methods have found application in other areas of dysfunctional cerebral hemodynamics: dementia, hypertension, migraines, and sepsis. Conclusion. Due to an excellent temporal resolution, non-invasive approach, good cost-benefit ratio, bedside monitoring, relative simplicity in terms of interpretation and performance, and portability, transcranial Doppler in vasomotor reactivity may be the ideal tool in the evaluation of cerebral hemodynamics, arterial perfusion integrity and collateral capacity.","PeriodicalId":18511,"journal":{"name":"Medicinski pregled","volume":"11 1","pages":"21-28"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78143550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Small bowel perforation following blunt abdominal trauma caused by an accidental hammer blow: A case report 意外锤击致腹部钝性创伤后小肠穿孔1例

Medicinski pregled Pub Date : 2020-01-01 DOI: 10.2298/mpns2004108d

Džemail Detanac, Mehmed Mujdragić, Dzenana A. Detanac, D. Bihorac, Mersudin Mulić

引用次数: 2

Primary aortoduodenal fistula without an abdominal aortic aneurysm: A case report 无腹主动脉瘤的原发性主动脉十二指肠瘘1例

Medicinski pregled Pub Date : 2020-01-01 DOI: 10.2298/mpns2006180t

Slobodan Torbica

引用次数: 0

Image-derived index - as a paramether for the semi-quantitative assessment of global tubular renal function 图像衍生指数-作为整体肾小管功能半定量评估的参数

Medicinski pregled Pub Date : 2020-01-01 DOI: 10.2298/mpns2006139s

Jelena Samac, R. Žeravica, B. Ilinčić, Marija Vukmirovic-Papuga, D. Burić, T. Ostojic

{"title":"Image-derived index - as a paramether for the semi-quantitative assessment of global tubular renal function","authors":"Jelena Samac, R. Žeravica, B. Ilinčić, Marija Vukmirovic-Papuga, D. Burić, T. Ostojic","doi":"10.2298/mpns2006139s","DOIUrl":"https://doi.org/10.2298/mpns2006139s","url":null,"abstract":"Introduction. Radionuclide methods are used in the evaluation of different aspects of renal function. The aim of this study was to define and implement an index derived from scintigraphic image and to compare it with ortho-iodohippurate clearance values, an indicator of effective renal plasma flow. Material and Methods. A retrospective analysis included 67 adult patients, who underwent static renal scintigraphy and ortho-iodohippurate clearance. We computed the background-to-renal index that represents the ratio of average values of counts per pixel in the background regions and in the regions of kidneys. Patients were divided into three groups according to the values of measured effective renal plasma flow: group 1 - patients with mild renal dysfunction (reduction of effective renal plasma flow ? 20%, 17 patients), group 2 - moderate dysfunction (reduction of effective renal plasma flow 20-50%, 25), and group 3 - severe dysfunction (reduction of effective renal plasma flow 50-70%, 25 patients). Results. Subjects with mild effective renal plasma flow reduction had significantly lower background-to-renal index values compared to those with moderate and severe reduction [(0.105 ? 0.05) vs. (0.134 ? 0.056) vs. (0.275 ? 0.154), p < 0,001]. A significant linear correlation was found between background-to-renal index and effective renal plasma flow (r = 0.60, p < 0.0001). Sensitivity and specificity of the calculated cut-off value of 0.1335, for the differentiation between the patients with renal reduction higher and lower than 20%, were 62% and 100%, respectively (area under curve 0.85). Conclusion. The background-to-renal index is a simple method for semiquantitative estimation of global tubular renal function that can be a useful tool when determining patients for further in vitro assessment of global renal function.","PeriodicalId":18511,"journal":{"name":"Medicinski pregled","volume":"169 1","pages":"139-144"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80615060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0