Sumatera Medical Journal最新文献_第9页

In Vitro Antimicrobial Activity of Bawang Batak Bulbs (Allium Chinense G. Don) Against Methicillin-Resistant Staphylococcus Aureus 霸王巴塔克球茎对耐甲氧西林金黄色葡萄球菌的体外抗菌活性研究

Sumatera Medical Journal Pub Date : 2019-06-01 DOI: 10.32734/SUMEJ.V2I2.1065

Tiasarah Aretha, N. Jusuf

{"title":"In Vitro Antimicrobial Activity of Bawang Batak Bulbs (Allium Chinense G. Don) Against Methicillin-Resistant Staphylococcus Aureus","authors":"Tiasarah Aretha, N. Jusuf","doi":"10.32734/SUMEJ.V2I2.1065","DOIUrl":"https://doi.org/10.32734/SUMEJ.V2I2.1065","url":null,"abstract":"Introduction: Staphylococcus aureus infection can cause pyoderma. These days there is a shift in Staphylococcus aureus sensitivity to antibiotics that is marked by the existence of Methicillin-Resistant Staphyloccus aureus, so alternative therapy that is herbal medicine might be needed. There are a lot of medicinal plants in Indonesia, but until today the usage is still minimum. One of the plant genus that is already being used is allium that had been known to have antimicrobial activity. The genus allium that is consumed a lot by Indonesians especially people of North Sumatra is bawang batak (Allium chinense G.Don.). This study is conducted to assess the antimicrobial activity of bawang batak bulbs in several concentrations to MRSA. Methods: This research is an experimental research with agar diffusion method. The extracts were divided into six groups: extracts in concentration level of 6.25%, 12.5%, 25%, 50%, 100% and a negative control (DMSO). The sample size is four per group with total sample of 24. Results: The results showed that the inhibition of bacterial growth occured at the concentration levels of 50% and 100% with inhibition zone diameters of 8.695 mm and 10.545 mm respectively. Extracts with concentration levels of 25%, 12.5% and 6.25% did not show any inhibition. Conclusion: Bawang batak bulbs extract can be used to inhibit the growth of MRSA","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133235187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Apoptotic Index Fails to Predict Chemoresponse in Breast Cancer 凋亡指数不能预测乳腺癌的化疗反应

Sumatera Medical Journal Pub Date : 2019-06-01 DOI: 10.32734/SUMEJ.V2I2.1062

K. Siregar

引用次数: 0

Changes In Glutamic Oxaloacetic Transaminase Serum (SGOT) and Glutamic Pyruvic Transaminase Serum (SGPT) Value In Laparoscopic Cholecystectomy Patient at USU Hospital USU医院腹腔镜胆囊切除术患者血清谷草转氨酶(SGOT)和谷丙转氨酶(SGPT)的变化

Sumatera Medical Journal Pub Date : 2019-04-20 DOI: 10.32734/SUMEJ.V3I2.3273

Aziizah Gita, Adi Muradi Muhar

{"title":"Changes In Glutamic Oxaloacetic Transaminase Serum (SGOT) and Glutamic Pyruvic Transaminase Serum (SGPT) Value In Laparoscopic Cholecystectomy Patient at USU Hospital","authors":"Aziizah Gita, Adi Muradi Muhar","doi":"10.32734/SUMEJ.V3I2.3273","DOIUrl":"https://doi.org/10.32734/SUMEJ.V3I2.3273","url":null,"abstract":"Background. Laparoscopic cholecystectomy has become more widely used choice compared to laparotomy cholecystectomy. Laparoscopic cholecystectomy has now become the gold standard of abdominal surgery for abdominal surgery for gallbladder abnormalities, more than 90% of patients with gallstone disease are treated surgically by laparoscopy, but several studies have revealed an increase in SGOT &SGPT values in these surgical procedures. SGPT itself occurs due to the procedure of laparoscopy. In the procedure, there is a temporary increase in the pneumoperitoneum, the pressure on the pneumoperitoneum and its duration affect the severity of ischemia by causing an increase in this liver enzyme. Among several studies, one of them revealed that at 48 hours after laparoscopic cholecystectomy surgery an enzyme increase. Objective. The purpose of the study, this research was conducted to see the changes in SGOT & SGPT values in laparoscopic cholecystectomy surgery. Method. This research method is analytic with cross sectional study design conducted at North Sumatera University Hospital. This research was conducted by looking at secondary data, namely the medical record of patients with gallstones who underwent laparoscopic cholecystectomy surgery from January 2019 to November 2019. The sample was selected by using total sampling method. Data were then analyzed using statistical application software. The number of samples was 45 samples with a diagnosis of gallstones who performed laparoscopic cholecystectomy. Results. Wilcoxon test results showed a significant change between SGOT and SGPT levels before performing operations with SGOT and SGPT levels after surgery with p=0.000 (p<0,05). Conclusion. There are changes in SGOT & SGPT in laparoscopic cholecystectomy.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"196 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120983652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Factors Affecting Gastrointestinal Disorders in Patients Undergoing Regular Hemodialysis 定期血液透析患者胃肠道疾病的影响因素

Sumatera Medical Journal Pub Date : 2019-04-20 DOI: 10.32734/SUMEJ.V3I2.3000

rosarina pasaribu, R. Muzasti

{"title":"Factors Affecting Gastrointestinal Disorders in Patients Undergoing Regular Hemodialysis","authors":"rosarina pasaribu, R. Muzasti","doi":"10.32734/SUMEJ.V3I2.3000","DOIUrl":"https://doi.org/10.32734/SUMEJ.V3I2.3000","url":null,"abstract":"Background: Chronic Kidney Disease (CKD) is an immense health issue. The prevalence is increasing each year worldwide, including Indonesia. Consistent with this trend, the prevalence of hemodialysis (HD) as a therapy is also increasing. CKD as well as HD often result in some complications, one being gastrointestinal disorders. Many factors are correlated with the incidence of gastrointestinal disorders in CKD patients undergoing HD. Objective: This research is held to observe the factors affecting gastrointestinal disorders in regular HD patients. Method: This is an observational analytical research with cross-sectional study at RS Khusus Ginjal Rasyida Medan. The datas used in the research are primary datas, obtained from Gastrointestinal Symptoms Rating Scale (GSRS) questionnaire to assess severity of gastrointestnal disorders in HD patients, and secondary datas, obtained from medical records of age, smoking history, use of aspirin, HD duration, BUN, and Kt/V (as a parameter of HD adequacy). Then the datas are analyzed univariately, bivariately, and mutivariately using biner logistic regression model. It is considered significant if the obtained p value is <0,05 (p<0,05). Result: All patients (100%) suffer from gastrointestinal disorders, with the most common being mild ones (67,1%). Final multivariate analysis shows that the duration of HD, BUN level, and Kt/V are significantly correlated with worsening gastrointestinal disorders (OR:14,157 ,95%CI 2,851 ± 71,183, p=0,001; OR: 8,352, 95%CI 0,914 ± 76,344, p= 0,060; OR:8,219 ,95%CI 0,893 ± 75,674, p= 0,063). Conclusion: The duration of HD, BUN level, and Kt/V are correlated with worsening gastrointestinal disorders in HD patients.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124957245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breast Cancer Patient Characeristics By Menarche In Adam Malik Hospital 2014-2017 2014-2017年亚当马利克医院乳腺癌患者月经初潮特征分析

Sumatera Medical Journal Pub Date : 2019-04-20 DOI: 10.32734/SUMEJ.V3I2.3277

cynthia ervina, Dedy Hermansyah

{"title":"Breast Cancer Patient Characeristics By Menarche In Adam Malik Hospital 2014-2017","authors":"cynthia ervina, Dedy Hermansyah","doi":"10.32734/SUMEJ.V3I2.3277","DOIUrl":"https://doi.org/10.32734/SUMEJ.V3I2.3277","url":null,"abstract":"Background. Breast cancer is one of the most diagnosed cancer in the world. Breast cancer starts when the breast cell grows abnormally and turns malignant. In Indonesia, breast cancer is the most diagnosed cancer in women. Up to now, the cause of breast cancer has not been identified yet. There are many factors that increase the risk of breast cancer, one of them is the early age of menarche. Objective. This study aims to obtain characteristics of breast cancer patients based on age of menarche in RSUP Haji Adam Malik in 2014-2017. Method. The study was designed in observational with descriptive method. The sampling had been done using total sampling technique. Results. Based on general characteristics, the majority of breast cancer patients are in the range of 40-49 years old (38,5%), graduated high school (45,2%), unemployed (66,3%), and do not have family history (94,2%). Majority of patients have stadium IIIB breast cancer (41,3%). The most diagnosed histopathology is Invasive Ductal Carcinoma (78,8%). Majority of breast cancer patients have negative estrogen receptor (67,3%), negative progesterone receptor (67,3%), negative her2 (66,3%) and positive ki-67 (67,3%). Fifty three breast cancer patients (51%) have early menarche. Based on the age of menarche, the patient with early menarche mostly has stage three breast cancer, but the age of menarche does not give a specific characteristic in histopathology and immunohistochemistry. Conclusion. Age of menarche gives specific characteristic in staging but not in histopathology and immunohistochemistry.","PeriodicalId":184699,"journal":{"name":"Sumatera Medical Journal","volume":"1967 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130132565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Timi Flow Between Streptokinase and Alteplase in Successful Fibrinolytic 纤溶成功的链激酶和阿替普酶之间的Timi流动

Sumatera Medical Journal Pub Date : 2019-01-30 DOI: 10.32734/SUMEJ.V2I1.716

Dika Ashrinda, R. Hasan, Cut A. Andra, Zulfikri Muhtar, H. Hasan

引用次数: 0

The Comparison of Er α Expression Between Endometriosis with No Endometriosis 子宫内膜异位症与无子宫内膜异位症Er α表达的比较

Sumatera Medical Journal Pub Date : 2019-01-30 DOI: 10.32734/SUMEJ.V2I1.714

D. Irsat Syafardi, H. Siregar, Y. B. Kaban, E. Ardiansyah

引用次数: 0

IHC Expression Relationships MMP7 and VEGF With Normal Ovaries and Ovarian Pathologies IHC中MMP7和VEGF表达与卵巢正常及卵巢病变的关系

Sumatera Medical Journal Pub Date : 2019-01-30 DOI: 10.32734/SUMEJ.V2I1.719

M. Rusda, R. Rivany, C. L. Hasibuan, D. Lutan, D. Aldiansyah, C. A. Adella