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A29. EMERGING CONCEPTS IN LUNG FIBROSIS最新文献

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Repurposing an Opioid Receptor Antagonist as a Treatment for Idiopathic Pulmonary Fibrosis 阿片受体拮抗剂作为特发性肺纤维化的治疗
A29. EMERGING CONCEPTS IN LUNG FIBROSIS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1228
D. Soundararajan, S. Madala, A. Jegga
{"title":"Repurposing an Opioid Receptor Antagonist as a Treatment for Idiopathic Pulmonary Fibrosis","authors":"D. Soundararajan, S. Madala, A. Jegga","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1228","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1228","url":null,"abstract":"","PeriodicalId":184655,"journal":{"name":"A29. EMERGING CONCEPTS IN LUNG FIBROSIS","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116408371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Defective Fatty Acid Metabolism Promotes Fibrosis in the Lung 缺陷脂肪酸代谢促进肺纤维化
A29. EMERGING CONCEPTS IN LUNG FIBROSIS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1245
D. Álvarez, M. Bueno, L. Tu, B. Kimball, G. Eric, M. Rojas, A. Mora
{"title":"Defective Fatty Acid Metabolism Promotes Fibrosis in the Lung","authors":"D. Álvarez, M. Bueno, L. Tu, B. Kimball, G. Eric, M. Rojas, A. Mora","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1245","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1245","url":null,"abstract":"","PeriodicalId":184655,"journal":{"name":"A29. EMERGING CONCEPTS IN LUNG FIBROSIS","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132878575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Monocyte-Derived Alveolar Macrophages Drive Enhanced Susceptibility to Non-Resolving Pulmonary Fibrosis During Aging 单核细胞来源的肺泡巨噬细胞在衰老过程中对非溶解性肺纤维化的易感性增强
A29. EMERGING CONCEPTS IN LUNG FIBROSIS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1230
Satoshi Watanabe, N. Joshi, R. Verma, R. Aillon, Ching‐I Chen, D. Kamp, G. Budinger, A. Misharin
{"title":"Monocyte-Derived Alveolar Macrophages Drive Enhanced Susceptibility to Non-Resolving Pulmonary Fibrosis During Aging","authors":"Satoshi Watanabe, N. Joshi, R. Verma, R. Aillon, Ching‐I Chen, D. Kamp, G. Budinger, A. Misharin","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1230","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1230","url":null,"abstract":"","PeriodicalId":184655,"journal":{"name":"A29. EMERGING CONCEPTS IN LUNG FIBROSIS","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121957404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alveolar Epithelial Fgfr2 Signaling Is Required for Recovery from Bleomycin-Induced Injury 肺泡上皮Fgfr2信号是博莱霉素诱导损伤恢复所必需的
A29. EMERGING CONCEPTS IN LUNG FIBROSIS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1241
R. Guzy, Samuel J. Dorry, A. Meliton, D. Ornitz, G. Mutlu
{"title":"Alveolar Epithelial Fgfr2 Signaling Is Required for Recovery from Bleomycin-Induced Injury","authors":"R. Guzy, Samuel J. Dorry, A. Meliton, D. Ornitz, G. Mutlu","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1241","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1241","url":null,"abstract":"","PeriodicalId":184655,"journal":{"name":"A29. EMERGING CONCEPTS IN LUNG FIBROSIS","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121590554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urine Proteomics Identifies Novel Biomarkers of IPF Disease Progression and Resolution 尿蛋白质组学鉴定IPF疾病进展和消退的新生物标志物
A29. EMERGING CONCEPTS IN LUNG FIBROSIS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1238
M. Decaris, M. Rexhepaj, J. Vowinckel, N. Dupuis, Ying‐Ying Wei, L. P. Hariri, J. Greenland, H. Chapman, Joyce S. Lee, P. Wolters, S. Turner
{"title":"Urine Proteomics Identifies Novel Biomarkers of IPF Disease Progression and Resolution","authors":"M. Decaris, M. Rexhepaj, J. Vowinckel, N. Dupuis, Ying‐Ying Wei, L. P. Hariri, J. Greenland, H. Chapman, Joyce S. Lee, P. Wolters, S. Turner","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1238","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1238","url":null,"abstract":"","PeriodicalId":184655,"journal":{"name":"A29. EMERGING CONCEPTS IN LUNG FIBROSIS","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115830194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Myeloid-Derived Suppressor Cells Orchestrate Immunosuppressive Networks in Idiopathic Pulmonary Fibrosis 特发性肺纤维化中骨髓源性抑制细胞协调免疫抑制网络
A29. EMERGING CONCEPTS IN LUNG FIBROSIS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1231
I. Fernandez, F. Greiffo, V. Viteri-Alvarez, I. Bastidas, R. Roy, M. Frankenberger, J. Behr, Alistair R. R. Forrest, A. Hilgendorff, O. Eickelberg
{"title":"Myeloid-Derived Suppressor Cells Orchestrate Immunosuppressive Networks in Idiopathic Pulmonary Fibrosis","authors":"I. Fernandez, F. Greiffo, V. Viteri-Alvarez, I. Bastidas, R. Roy, M. Frankenberger, J. Behr, Alistair R. R. Forrest, A. Hilgendorff, O. Eickelberg","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1231","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1231","url":null,"abstract":"","PeriodicalId":184655,"journal":{"name":"A29. EMERGING CONCEPTS IN LUNG FIBROSIS","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132589260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expression of a Prototypical Surfactant Protein C BRICHOS Mutation Causes Epithelial ER Stress, Spontaneous Lung Injury and Fibrotic Remodeling 典型表面活性剂蛋白C BRICHOS突变的表达可引起上皮内质网应激、自发性肺损伤和纤维化重塑
A29. EMERGING CONCEPTS IN LUNG FIBROSIS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1246
M. Barrett, J. Katzen, A. Venosa, Scott J. Russo, M. Beers
{"title":"Expression of a Prototypical Surfactant Protein C BRICHOS Mutation Causes Epithelial ER Stress, Spontaneous Lung Injury and Fibrotic Remodeling","authors":"M. Barrett, J. Katzen, A. Venosa, Scott J. Russo, M. Beers","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1246","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1246","url":null,"abstract":"","PeriodicalId":184655,"journal":{"name":"A29. EMERGING CONCEPTS IN LUNG FIBROSIS","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127430745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Peptidylarginine Deiminase 4 Contributes to the Profibrotic Phenotype of Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis and Promotes Experimental Pulmonary Fibrosis 肽精氨酸脱亚胺酶4参与特发性肺纤维化患者成纤维细胞的纤维化表型并促进实验性肺纤维化
A29. EMERGING CONCEPTS IN LUNG FIBROSIS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1239
A. Esposito, S. Chu, S. Frías, B. Sun, T. Doyle, S. El-Chemaly, M. Perrella, I. Ho, K. Tsoyi, I. Rosas
{"title":"Peptidylarginine Deiminase 4 Contributes to the Profibrotic Phenotype of Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis and Promotes Experimental Pulmonary Fibrosis","authors":"A. Esposito, S. Chu, S. Frías, B. Sun, T. Doyle, S. El-Chemaly, M. Perrella, I. Ho, K. Tsoyi, I. Rosas","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1239","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1239","url":null,"abstract":"","PeriodicalId":184655,"journal":{"name":"A29. EMERGING CONCEPTS IN LUNG FIBROSIS","volume":"293 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125751240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Omipalasib Modulates Extracellular Matrix Turnover in IPF Patients: Exploratory Biomarker Analysis from a Phase I Proof of Mechanism Study Omipalasib调节IPF患者的细胞外基质转换:从机制研究的I期证明的探索性生物标志物分析
A29. EMERGING CONCEPTS IN LUNG FIBROSIS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7301
C. Nanthakumar, J. Eley, Yim Man, N. Gudmann, R. Chambers, A. Blanchard, W. Fahy, T. Maher
{"title":"Omipalasib Modulates Extracellular Matrix Turnover in IPF Patients: Exploratory Biomarker Analysis from a Phase I Proof of Mechanism Study","authors":"C. Nanthakumar, J. Eley, Yim Man, N. Gudmann, R. Chambers, A. Blanchard, W. Fahy, T. Maher","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7301","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7301","url":null,"abstract":"","PeriodicalId":184655,"journal":{"name":"A29. EMERGING CONCEPTS IN LUNG FIBROSIS","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127531987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Circulating Plasma Proteins Differentially Detected in Idiopathic Pulmonary Fibrosis and in Subjects with Pre-Clinical Pulmonary Fibrosis 特发性肺纤维化和临床前肺纤维化患者循环血浆蛋白的差异检测
A29. EMERGING CONCEPTS IN LUNG FIBROSIS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1237
S. Mathai, Fabian Metzger, J. Cardwell, J. Kropski, J. Powers, A. Walts, C. Markin, K. Brown, M. Steele, M. Schwarz, D. Lynch, O. Eickelberg, T. Fingerlin, J. Loyd, S. Hauck, Ivana V. Yang, D. A. Schwartz
{"title":"Circulating Plasma Proteins Differentially Detected in Idiopathic Pulmonary Fibrosis and in Subjects with Pre-Clinical Pulmonary Fibrosis","authors":"S. Mathai, Fabian Metzger, J. Cardwell, J. Kropski, J. Powers, A. Walts, C. Markin, K. Brown, M. Steele, M. Schwarz, D. Lynch, O. Eickelberg, T. Fingerlin, J. Loyd, S. Hauck, Ivana V. Yang, D. A. Schwartz","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1237","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1237","url":null,"abstract":"","PeriodicalId":184655,"journal":{"name":"A29. EMERGING CONCEPTS IN LUNG FIBROSIS","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131659417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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