Leprosy review最新文献

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Dr. K V Desikan MD K V设计博士
IF 0.6 4区 医学
Leprosy review Pub Date : 2023-03-01 DOI: 10.47276/lr.94.1.95
V. D. Ramanathan
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引用次数: 0
Validating an Amharic version of the 36-Item Short Form Health Survey (SF-36) in individuals with leprosy in Ethiopia 在埃塞俄比亚麻风病患者中验证阿姆哈拉语版本的36项简短健康调查(SF-36)
4区 医学
Leprosy review Pub Date : 2023-03-01 DOI: 10.47276/lr.94.1.53
Saba Maria Lambert, Shimelis Nigusse, Digafe Alembo, Stephen Walker, Peter Nicholls, Diana Nancy Lockwood
{"title":"Validating an Amharic version of the 36-Item Short Form Health Survey (SF-36) in individuals with leprosy in Ethiopia","authors":"Saba Maria Lambert, Shimelis Nigusse, Digafe Alembo, Stephen Walker, Peter Nicholls, Diana Nancy Lockwood","doi":"10.47276/lr.94.1.53","DOIUrl":"https://doi.org/10.47276/lr.94.1.53","url":null,"abstract":"Background Health-related quality of life (HRQoL) has now become an indispensable outcome measure in many randomized clinical trials and other studies. It provides the patient’s voice in measuring health improvement or decline and assessing treatment effectiveness. A validated Amharic version of HRQoL assessment tool was needed for leprosy clinical trials in Ethiopia. The SF-36 was chosen but a validated Amharic version was not available. We describe how this was developed. Methods The SF-36 was translated from English into Amharic and evaluated for content acceptability in a patient focus group. Back translation was performed. Validity and reliability of the Amharic SF-36 in leprosy affected individuals was tested with 100 patients with leprosy attending the leprosy clinic at ALERT hospital and compared to the Amharic version of the WHOQOL-BREF. Results Amharic versions of both the WHOQOL-BREF and the SF-36 had good reliability and validity amongst leprosy affected individuals. Internal consistency reliability estimates for each domain/scale exceeded 0.70. The Amharic SF-36 had better convergent and discriminant validity than WHOQOL-BREF in this group of patients. Good known-group validity was seen in both WHOQOL-BREF and SF-36 in leprosy affected patients. The Amharic SF-36 had good inter-rater reliability with seven out of 8 domains scoring above 0.8 in intra-class correlation. Conclusion This Amharic version of the SF-36 is a valid instrument to measure HRQoL in studies and clinical settings involving leprosy affected individuals in Ethiopia.","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135130121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of esxA, hsp18, and 16S transcript expression as a measure of Mycobacterium leprae viability: A comparison with the mouse footpad assay esxA、hsp18和16S转录物表达作为麻风分枝杆菌生存能力的评估:与小鼠足垫试验的比较
IF 0.6 4区 医学
Leprosy review Pub Date : 2023-03-01 DOI: 10.47276/lr.94.1.7
J. Hunter Collins, Shannon M Lenz, Nashone A. Ray, R. Lahiri, L. Adams
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引用次数: 0
Health workers’ perceptions of leprosy and factors influencing their perceptions in endemic countries: A systematic literature review 流行国家卫生工作者对麻风病的认知及其影响因素:系统文献综述
IF 0.6 4区 医学
Leprosy review Pub Date : 2022-12-01 DOI: 10.47276/lr.93.4.332
E. Haverkort, A. T. van 't Noordende
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引用次数: 2
Rising percentage of new female leprosy cases since 2004 自2004年以来新增女性麻风病病例的百分比不断上升
IF 0.6 4区 医学
Leprosy review Pub Date : 2022-12-01 DOI: 10.47276/lr.93.4.364
Emily E V Quilter, D. Lockwood, C. Ruth Butlin
{"title":"Rising percentage of new female leprosy cases since 2004","authors":"Emily E V Quilter, D. Lockwood, C. Ruth Butlin","doi":"10.47276/lr.93.4.364","DOIUrl":"https://doi.org/10.47276/lr.93.4.364","url":null,"abstract":"","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47217069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short report for Leprosy Review: ILEP Conference, 2022: Active case-finding 麻风病审查简短报告:2022年ILEP会议:积极的病例发现
IF 0.6 4区 医学
Leprosy review Pub Date : 2022-12-01 DOI: 10.47276/lr.93.4.424
G. Warne, Monty Mukhier
{"title":"Short report for Leprosy Review: ILEP Conference, 2022: Active case-finding","authors":"G. Warne, Monty Mukhier","doi":"10.47276/lr.93.4.424","DOIUrl":"https://doi.org/10.47276/lr.93.4.424","url":null,"abstract":"","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41481602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Guillain-Barré syndrome following a Type 2 leprosy reaction: A case report 2型麻风病反应后的格林-巴利综合征一例报告
IF 0.6 4区 医学
Leprosy review Pub Date : 2022-12-01 DOI: 10.47276/lr.93.4.420
D. F. dos Santos, Victor Herlys Gomes Braga, Thales Junqueira Oliveira, Isabella Sabião Borges, I. Goulart
{"title":"Guillain-Barré syndrome following a Type 2 leprosy reaction: A case report","authors":"D. F. dos Santos, Victor Herlys Gomes Braga, Thales Junqueira Oliveira, Isabella Sabião Borges, I. Goulart","doi":"10.47276/lr.93.4.420","DOIUrl":"https://doi.org/10.47276/lr.93.4.420","url":null,"abstract":"","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42728308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What factors influence adherence and non-adherence to multi-drug therapy for the treatment of leprosy within the World Health Organisation South East Asia region? A systematic review 在世界卫生组织东南亚地区,哪些因素影响对麻风病多种药物治疗的坚持和不坚持?系统综述
IF 0.6 4区 医学
Leprosy review Pub Date : 2022-12-01 DOI: 10.47276/lr.93.4.311
T. Meadows, G. Davey
{"title":"What factors influence adherence and non-adherence to multi-drug therapy for the treatment of leprosy within the World Health Organisation South East Asia region? A systematic review","authors":"T. Meadows, G. Davey","doi":"10.47276/lr.93.4.311","DOIUrl":"https://doi.org/10.47276/lr.93.4.311","url":null,"abstract":"SummaryIntroduction Leprosy is an infection caused by Mycobacterium leprae . Despite curative treatment being available, leprosy is still prevalent worldwide, with little change in annual cases observed in the past decade. The WHO South East Asia region is the worst affected, accounting for over 70% of new cases. One reason leprosy transmission still occurs is non-adherence to multi-drug therapy. This project aims to determine the factors that influence adherence. Methods A systematic review was performed using 6 databases. This returned 402 unique results. Screening of the title and abstract resulted in 362 of these being excluded. From the remaining 40, full-text analysis identified 17 studies that met the inclusion criteria and formed the review. Both qualitative and quantitative methods of collecting and analyzing data were used to form a non-quantitative synthesis of the findings. Results Four factors influenced adherence: medication-related, healthcare-related, patient-related and society-related. From these, lack of knowledge about leprosy and multi-drug therapy was a predominant barrier to adherence, which related to all of these factors. Stigma and being female were also seen as important barriers to adherence - these manifested in numerous ways. Conclusion The review identified diverse barriers to adherence to MDT and no simple intervention will overcome these. Rather, wider issues such as continuous access to healthcare (particularly for women), stigma reduction and patient education need to be addressed. Improving these will increase patient confidence in, and access to, MDT, which will ultimately result in improved adherence to therapy.","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46005447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short report for Leprosy Review: ILEP Conference, 2022: Health system strengthening 麻风回顾的简短报告:ILEP会议,2022:加强卫生系统
IF 0.6 4区 医学
Leprosy review Pub Date : 2022-12-01 DOI: 10.47276/lr.93.4.431
G. Warne, Monty Mukhier
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引用次数: 0
Improving early case detection in leprosy: Reports from recent workshops 改进麻风病的早期病例发现:最近讲习班的报告
IF 0.6 4区 医学
Leprosy review Pub Date : 2022-12-01 DOI: 10.47276/lr.93.4.292
P. Saunderson
{"title":"Improving early case detection in leprosy: Reports from recent workshops","authors":"P. Saunderson","doi":"10.47276/lr.93.4.292","DOIUrl":"https://doi.org/10.47276/lr.93.4.292","url":null,"abstract":"","PeriodicalId":18196,"journal":{"name":"Leprosy review","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44646078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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