Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society最新文献_第5页

Changing perspectives on the role of corticosteroids after liver transplantation. 对肝移植后皮质类固醇作用的不同看法。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 1999-07-01 DOI: 10.1053/JTLS005s00058

M R Lucey

引用次数: 7

Evaluating strategies for reducing the costs of immunosuppression. 评估降低免疫抑制成本的策略。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 1999-07-01 DOI: 10.1053/JTLS005s00115

K J Gorman

引用次数: 0

Acute and chronic hepatic allograft rejection: pathology and classification. 急性和慢性肝移植排斥反应:病理和分类。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 1999-07-01 DOI: 10.1053/JTLS005s00021

K P Batts

引用次数: 45

Use of antilymphocyte induction therapy in liver transplantation: A European perspective. 抗淋巴细胞诱导治疗在肝移植中的应用:欧洲视角。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 1999-07-01 DOI: 10.1053/JTLS005s00071

J M Langrehr, P J Neuhaus

引用次数: 1

Hepatic Allograft Rejection and Evolving Immunosuppression Strategies. Proceedings of the AASLD/ILTS transplant course. Chicago, Illinois, USA. November 8, 1998. 肝移植排斥反应和免疫抑制策略的进化。AASLD/ILTS移植课程论文集。芝加哥，伊利诺伊州，美国。1998年11月8日。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 1999-07-01

引用次数: 0

Shunt versus transplantation. 分流与移植。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 1998-09-01

A N Langnas

引用次数: 0

Treatment of hepatocellular carcinoma: medical options. 肝细胞癌的治疗:医疗选择

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 1998-09-01

M W Fried

引用次数: 0

Transplantation for childhood liver disease: an overview. 儿童肝脏疾病的移植:综述

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 1998-09-01

W F Balistreri

{"title":"Transplantation for childhood liver disease: an overview.","authors":"W F Balistreri","doi":"","DOIUrl":"","url":null,"abstract":"The advances made in surgical technique, postoperative care, and immunosuppression during the 1980s have permitted orthotopic liver transplantation (OLT) to evolve into an effective and widely accepted therapy for infants and children with end-stage liver disease. Biliary atresia, a progressive, obliterative disease of the bile ducts, is the most common indication for OLT in children, accounting for approximately 50% of cases. Metabolic liver disease (MLD) accounts for 20% to 25%; other common indications for OLT include fulminant hepatic failure (FHF) and forms of intrahepatic cholestasis. The principal problem associated with the increasing application of OLT is the burden placed on resources, particularly the availability of donor organs. The limited pool of size-matched donor organs has led to the application of a variety of alternatives to address the needs of the pediatric recipient; these include (1) reduced-size liver transplantation, (2) \"split-liver\" transplantation, and (3) use of living-related organ donors. In view of the impact on overall organ availability, the use of nontransplant options, including liver cell transplantation, especially for FHF and MLD, deserves broader application. Despite the success of transplantation, major challenges in childhood liver transplantation remain, including (1) improved preoperative management to ensure adequate growth, (2) more precise posttransplant management of immunosuppression to ensure graft viability and avoidance of lymphoproliferative disease, (3) earlier recognition of cytomegalovirus and Epstein-Barr virus infection, and (4) provision of services in a more cost-effective manner. The ultimate solution is to prevent liver disease through vaccination and research.","PeriodicalId":18112,"journal":{"name":"Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20656462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One center's experience with liver transplantation: alcohol use relapse over the long-term. 一个中心的肝移植经验:长期饮酒复发。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 1998-09-01

D A Campbell, J C Magee, J D Punch, R M Merion, J G Turcotte, J S Bromberg

引用次数: 0

Liver transplantation for primary biliary cirrhosis and primary sclerosing cholangitis: does medical treatment alter timing and selection? 原发性胆汁性肝硬化和原发性硬化性胆管炎的肝移植:药物治疗会改变时机和选择吗?

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 1998-09-01

J E Hay

{"title":"Liver transplantation for primary biliary cirrhosis and primary sclerosing cholangitis: does medical treatment alter timing and selection?","authors":"J E Hay","doi":"","DOIUrl":"","url":null,"abstract":"Liver transplantation is a highly effective treatment for patients with advanced primary biliary cirrhosis and primary sclerosing cholangitis. Transplantation is indicated when the patient's survival with transplantation is better than without or, earlier than this, if the patient's quality of life is intolerable from intractable fatigue or pruritus. Medical therapies for chronic cholestatic liver diseases are very limited. Ursodeoxycholic acid therapy in primary biliary cirrhosis reduces cholestasis and prolongs transplant-free survival; no other drugs are of proven efficacy in primary biliary cirrhosis, and none have any benefit on the disease progression of primary sclerosing cholangitis. Aggressive endoscopic therapy may produce symptomatic and biochemical improvement in primary sclerosing cholangitis but should be done without the expectation of retarding disease progression. Bilirubin is one of five criteria of the Child-Turcotte-Pugh score, which is necessary for the United Network for Organ Sharing listing for orthotopic liver transplantation. In addition, it is a major prognostic indicator in all the predictive models for primary biliary cirrhosis. Bilirubin reduction with ursodeoxycholic acid therapy in primary biliary cirrhosis appears to parallel disease severity, and prognostic models utilizing bilirubin retain their predictive power for survival even in treated patients. In summary, medical therapies for chronic cholestatic liver disease have very little effect on disease progression and, subsequently, on the timing or selection for transplantation. Liver transplantation is the only definitive therapy for primary biliary cirrhosis and primary sclerosing cholangitis.","PeriodicalId":18112,"journal":{"name":"Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20656615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0