Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society最新文献_第3页

Protein Maturation and Processing at the Endoplasmic Reticulum 内质网的蛋白质成熟和加工

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 2009-10-06 DOI: 10.1002/9780470747919.CH11

R. Hegde

引用次数: 1

Adaptive Regulation of Hepatocyte Transporters in Cholestasis 胆汁淤积症中肝细胞转运体的适应性调节

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 2009-10-06 DOI: 10.1002/9780470747919.CH43

J. Boyer

引用次数: 3

Protein Degradation and the Lysosomal System 蛋白质降解和溶酶体系统

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 2009-10-06 DOI: 10.1002/9780470747919.CH12

Susmita Kaushik, A. Cuervo

引用次数: 1

Lipoprotein Metabolism and Cholesterol Balance 脂蛋白代谢和胆固醇平衡

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 2009-10-06 DOI: 10.1002/9780470747919.CH19

D. Cohen

引用次数: 7

Is there any benefit to laparoscopic liver resection for hepatocellular carcinoma if a salvage liver transplant is needed later? 如果以后需要补救性肝移植，腹腔镜肝切除术对肝细胞癌有什么好处吗?

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 2009-07-01 DOI: 10.1002/LTS.21800

J. Perkins

{"title":"Is there any benefit to laparoscopic liver resection for hepatocellular carcinoma if a salvage liver transplant is needed later?","authors":"J. Perkins","doi":"10.1002/LTS.21800","DOIUrl":"https://doi.org/10.1002/LTS.21800","url":null,"abstract":"Background/Purpose: In patients with hepatocellular carcinoma (HCC), a previous liver resection (LR) may compromise subsequent liver transplantation (LT) by creating adhesions and increasing surgical difficulty. Initial laparoscopic LR (LLR) may reduce such technical consequences, but its effect on subsequent LT has not been reported. We report the operative results of LT after laparoscopic or open liver resection (OLR). Methods: Twenty-four LT were performed, 12 following prior LLR and 12 following prior OLR. The LT was performed using preservation of the inferior vein cava. Indication for the LT was recurrent HCC in 19 cases (salvage LT), while five patients were listed for LT and underwent resection as a neoadjuvant procedure (bridge resection). Results: In the LLR group, absence of adhesions was associated with straightforward access to the liver in all cases. In the OLR group, 11 patients required long and hemorrhagic dissection. Median durations of the hepatectomy phase and whole LT were 2.5 and 6.2 h, and 4.5 and 8.3 h in the LLR and OLR groups, respectively (P < 0.05). Median blood loss was 1200 ml and 2300 ml in the LLR and OLR groups, respectively (P < 0.05). Median transfusions of hepatectomy phase and whole LT were 0 and 3 U, and 2 and 6 U, respectively (P < 0.05). There were no postoperative deaths. Conclusions: In our study, LLR facilitated the LT procedure as compared with OLR in terms of reduced operative time, blood loss and transfusion requirements. We conclude that LLR should be preferred over OLR when feasible in potential transplant candidates.","PeriodicalId":18112,"journal":{"name":"Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80448525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The evolution of caval implantation in liver transplantation. 肝移植腔静脉植入技术的发展。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 2007-01-01 DOI: 10.1002/lt

J. Perkins

{"title":"The evolution of caval implantation in liver transplantation.","authors":"J. Perkins","doi":"10.1002/lt","DOIUrl":"https://doi.org/10.1002/lt","url":null,"abstract":"Conventional orthotopic liver transplantation (CON-LT) involves resection of recipient cava, usually with extra-corporeal circulation (veno-venous bypass, VVB), while in the piggyback technique (PC-LT) the cava is preserved. Along with a temporary portacaval shunt (TPCS), better haemodynamic maintenance is purported with PC-LT. A prospective, consecutive series of 384 primary transplants (2000-2003) were analysed, 138 CON-LT (with VVB) and 246 PC-LT (54 without TPCS). Patient/donor characteristics were similar in the two groups. PC-LT required less usage of fresh-frozen plasma and platelets, intensive care stay, number of patients requiring ventilation after day 1 and total days spent on ventilator. The results were not different when comparing, total operating and warm ischaemia time (WIT), red cell usage, requirement for renal support, day 3 serum creatinine and total hospital stay. TPCS had no impact on outcome other than WIT (P = 0.02). Three patients in PC-LT group (three of 246; 1.2%) developed caval outflow obstruction (P = 0.02). There was no difference in short- or long-term graft or patient survival. PC-LT has an advantage over CON-LT using VVB with respect to intraoperative blood product usage, postoperative ventilation requirement and ITU stay. VVB is no longer required and TPCS may be used selectively in adult transplantation. (Transpl Int 2006;19:795-801.)","PeriodicalId":18112,"journal":{"name":"Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78325873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Endoscopic retrograde cholangiography in post-orthotopic liver transplant population with Roux-en-Y biliary reconstruction. 内镜逆行胆道造影在原位肝移植术后Roux-en-Y胆道重建中的应用。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 2005-04-01 DOI: 10.1016/S0016-5107(05)01138-7

P. Chahal, T. Baron, J. Poterucha, C. Rosen

引用次数: 29

Hepatic tissue engineering for adjunct and temporary liver support: critical technologies. 辅助和临时肝支持的肝组织工程:关键技术。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 2004-01-01 DOI: 10.1201/9781420003871.ch59

Christina Chan, F. Berthiaume, Bharath D. Nath, A. Tilles, M. Toner, M. Yarmush

{"title":"Hepatic tissue engineering for adjunct and temporary liver support: critical technologies.","authors":"Christina Chan, F. Berthiaume, Bharath D. Nath, A. Tilles, M. Toner, M. Yarmush","doi":"10.1201/9781420003871.ch59","DOIUrl":"https://doi.org/10.1201/9781420003871.ch59","url":null,"abstract":"The severe donor liver shortage, high cost, and complexity of orthotopic liver transplantation have prompted the search for alternative treatment strategies for end-stage liver disease, which would require less donor material, be cheaper, and less invasive. Hepatic tissue engineering encompasses several approaches to develop adjunct internal liver support methods, such as hepatocyte transplantation and implantable hepatocyte-based devices, as well as temporary extracorporeal liver support techniques, such as bioartificial liver assist devices. Many tissue engineered liver support systems have passed the \"proof of principle\" test in preclinical and clinical studies; however, they have not yet been found sufficiently reliably effective for routine clinical use. In this review we describe, from an engineering perspective, the progress and remaining challenges that must be resolved in order to develop the next generation of implantable and extracorporeal devices for adjunct or temporary liver assist.","PeriodicalId":18112,"journal":{"name":"Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91512440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 58

Tacrolimus ameliorates cerebral vasodilatation and intracranial hypertension in the rat with portacaval anastomosis and hyperammonemia. 他克莫司改善门静脉吻合伴高氨血症大鼠脑血管舒张和颅内高压。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 2004-01-01 DOI: 10.1016/S0168-8278(04)90142-0

T. Dethloff, B. Hansen, F. Larsen

引用次数: 4

Usefulness of albumin scintigraphy in a pediatric liver transplant recipient with gastrointestinal posttransplant lymphoproliferative disorder. 白蛋白显像在小儿肝移植受者并发胃肠道移植后淋巴细胞增生性疾病中的应用价值。

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Pub Date : 2002-06-01 DOI: 10.1053/JLTS.2002.30593A

A. Mita, Y. Hashikura, M. Momose, J. Nakayama, E. Sasaki, T. Ikegami, Y. Nakazawa, H. Chisuwa, M. Terada, S. Kawasaki

引用次数: 1