Libyan International Medical University Journal最新文献_第8页

Medical education in Libya: Challenges, hopes, and recommendations 利比亚的医学教育:挑战、希望和建议

Libyan International Medical University Journal Pub Date : 2019-01-01 DOI: 10.4103/LIUJ.LIUJ_3_19

A. Al-areibi

引用次数: 4

Exploring the relationship between air pollution and health of children: A global perspective 探讨空气污染与儿童健康之间的关系:全球视角

Libyan International Medical University Journal Pub Date : 2019-01-01 DOI: 10.4103/liuj.liuj_4_19

S. Shrivastava, P. Shrivastava

引用次数: 0

Ensuring strengthening and expansion of the prevention and control activities for the elimination of hepatitis C 确保加强和扩大预防和控制活动，以消除丙型肝炎

Libyan International Medical University Journal Pub Date : 2019-01-01 DOI: 10.4103/liuj.liuj_36_18

S. Shrivastava, P. Shrivastava

引用次数: 0

Determination of some heavy metals in cosmetic products collected from Benghazi-Libya markets during 2016 2016年班加西-利比亚市场化妆品中重金属含量测定

Libyan International Medical University Journal Pub Date : 2019-01-01 DOI: 10.4103/LIUJ.LIUJ_44_18

Salwa Rahil, Intisar A. Elshara, N. Ahmida, M. Ahmida

{"title":"Determination of some heavy metals in cosmetic products collected from Benghazi-Libya markets during 2016","authors":"Salwa Rahil, Intisar A. Elshara, N. Ahmida, M. Ahmida","doi":"10.4103/LIUJ.LIUJ_44_18","DOIUrl":"https://doi.org/10.4103/LIUJ.LIUJ_44_18","url":null,"abstract":"Introduction: Cosmetics have been utilized by most of the people irrespective of their race, gender, or age to beautify, modify, or improve the physical appearance. Many cosmetic products contain heavy metals as ingredients or impurities. Recent research has reported that these metals can cause many types of health and skin problems. Aims: The aim of this study is to detect the levels of heavy metals in some cosmetic products that are available in cosmetic shops around the city of Benghazi. Materials and Methods: Twenty-five of cheap facial cosmetic products that are widely in demand in cosmetic shops in Benghazi were collected in April 2016. The samples included eight kohl, seven eyeliners, and ten lipsticks. Metals including iron, copper, chromium, zinc, lead, and cadmium were analyzed in the selected samples using flame atomic absorption spectrophotometer after suitable digestion process. Results: Our results indicated that iron and copper were detected in all samples with concentration ranges varying from 0.5 to 124.5 mg/kg for iron and 1.8–51.4 mg/kg for copper. The concentration ranges of chromium, zinc, cadmium, and lead were varied from 0.0 to 7.25 mg/kg, 0.0 to 22.75, 0.0 to 125.0 mg/kg, and 0.0 to 20.25 mg/kg, respectively. Conclusions: The results showed that the selected metals were detected in most of the samples at varying concentrations. Kohl samples have the highest concentration of the analyzed metals. According to the maximum allowed limits recommended by the World Health Organization (WHO) for toxic metals in cosmetics, there was only one sample that had lead concentration higher than the maximum limit recommended by the WHO. In addition, there were twenty samples that had concentrations of cadmium above the WHO legislation limits.","PeriodicalId":18106,"journal":{"name":"Libyan International Medical University Journal","volume":"191 1","pages":"10 - 17"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85003560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Preventing newborn deaths in marginalized population groups 预防边缘人口群体的新生儿死亡

Libyan International Medical University Journal Pub Date : 2019-01-01 DOI: 10.4103/liuj.liuj_48_18

S. Shrivastava, P. Shrivastava

引用次数: 0

Childhood tuberculosis in a South-East Nigerian tertiary hospital: Treatment outcomes and determinants 尼日利亚东南部一家三级医院的儿童结核病:治疗结果和决定因素

Libyan International Medical University Journal Pub Date : 2019-01-01 DOI: 10.4103/LIUJ.LIUJ_47_18

C. Onubogu, E. Ugochukwu, A. Anyabolu, J. Ojukwu

{"title":"Childhood tuberculosis in a South-East Nigerian tertiary hospital: Treatment outcomes and determinants","authors":"C. Onubogu, E. Ugochukwu, A. Anyabolu, J. Ojukwu","doi":"10.4103/LIUJ.LIUJ_47_18","DOIUrl":"https://doi.org/10.4103/LIUJ.LIUJ_47_18","url":null,"abstract":"Background and Objectives: Tuberculosis (TB) is an important cause of childhood morbidity and mortality. Understanding the barriers to successful childhood TB treatment is vital to curbing the scourge of childhood TB. This study examined the outcomes and factors that influence the outcomes of childhood TB treatment in a South-East Nigerian tertiary hospital. Methods: A 10-year review of the medical records of under-15 year olds, who received anti-TB treatment at Nnamdi Azikiwe University Teaching Hospital, Nnewi, was carried out. Data were analyzed using SPSS version 20. Results: Majority of the 501 childhood TB cases were new (89.6%) and pulmonary (73.3%) TB cases. TB-HIV coinfection occurred in 42.5% of cases. The rate of successful treatment was 62.9%. About 57.5% completed treatment, 5.4% were cured, 7.0% were transferred out, 21.4% were lost to follow-up, 0.4% had treatment failure while 8.4% died. Majority (61.6%) of deaths or loss to follow-up occurred during the first 2 months of treatment. Factors significantly associated with treatment outcomes were ascertainment of HIV status (P = 0.049), disease site (P = 0.013), nutritional status (P = 0.039), Mantoux test result (P = 0.002), and period of treatment (P = 0.005). Conclusion: Findings indicate high rate of unsuccessful childhood TB treatment outcomes. Efforts should be intensified to ensure improved outcomes through proactive search for childhood TB cases, early diagnosis and treatment, as well as adherence to and completion of treatment. Special attention should be given to high-risk groups including those with unknown HIV status, extrapulmonary TB, and severe malnutrition. It is imperative to determine the HIV status of all childhood TB cases.","PeriodicalId":18106,"journal":{"name":"Libyan International Medical University Journal","volume":"136 1","pages":"18 - 25"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73747174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The redesign of amoxicillin capsules as a tablet dosage form using direct compression 重新设计阿莫西林胶囊作为片剂剂型使用直接压缩

Libyan International Medical University Journal Pub Date : 2019-01-01 DOI: 10.4103/LIUJ.LIUJ_45_18

Salem Elgahmi, Nawal Alrishei, Rabeaa Algaraboly, Aisha Altrablesy, I. El-Mahdi

{"title":"The redesign of amoxicillin capsules as a tablet dosage form using direct compression","authors":"Salem Elgahmi, Nawal Alrishei, Rabeaa Algaraboly, Aisha Altrablesy, I. El-Mahdi","doi":"10.4103/LIUJ.LIUJ_45_18","DOIUrl":"https://doi.org/10.4103/LIUJ.LIUJ_45_18","url":null,"abstract":"Introduction: Solid dosage forms are the most commonly used dosage form for drug delivery, and tablets are more popular than capsules because of its lower production cost, minimal potential of content tampering, and the large number of designs of tablets for various applications. Aims: The aim of this work is to redesign amoxicillin hard gelatin capsules (HGCs), commonly filled into HGCs, into tablet dosage form by employing preformulation principles. Materials and Methods: Amoxicillin capsules were obtained from the local market for this purpose. Experiments included studies on flowability and effect of compression force, followed by addition of excipients, production of tablets by direct compression, and evaluation employing standard methods of friability, hardness, disintegration, dissolution, and simulation of release kinetics. Results: The flowability of powder was estimated using Carr's index, Hausner ratio, angle of repose, and bulk density. The flowability was found poor for amoxicillin alone or with starch but improved with talc. Compression force was found to be a significant factor on friability, hardness, and disintegration. The disintegration time was rapid in case of tablets containing starch compared to amoxicillin powder compressed alone. It was essential to include small amounts of disintegrant and a lubricant to optimize tablet properties. Dissolution rates for the prepared tablets were found to be acceptable, while some formulations showed a slow release profiles corresponding to their slow disintegration. Release kinetics was found to follow both the zero-order and matrix models. Conclusion: Amoxicillin capsules can be modified to a tablet dosage form with simple handling of preformulation properties.","PeriodicalId":18106,"journal":{"name":"Libyan International Medical University Journal","volume":"3 1","pages":"33 - 38"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87591156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The physical, chemical, and microbiological stability of chloramphenicol ophthalmic solution 氯霉素眼药水的物理、化学和微生物稳定性

Libyan International Medical University Journal Pub Date : 2018-07-01 DOI: 10.4103/LIUJ.LIUJ_16_18

Tauwfik M. Salih, I. El-Mahdi

{"title":"The physical, chemical, and microbiological stability of chloramphenicol ophthalmic solution","authors":"Tauwfik M. Salih, I. El-Mahdi","doi":"10.4103/LIUJ.LIUJ_16_18","DOIUrl":"https://doi.org/10.4103/LIUJ.LIUJ_16_18","url":null,"abstract":"Aims: The aim of this work is to “predict” the remaining shelf-life of chloramphenicol (CH) eye drops, commercially marketed, using the theoretical “Longland–Rowbotham model,”” followed by confirmation of findings by practical means. Materials and Methods: The methods used for the evaluation of CH-eye drops included the assay of the active ingredient, sterility testing, and minimum inhibitory concentration (MIC) determination using official methods during 6 months stability study at variable temperatures (4, 25°C). Furthermore, a 3-month accelerated stability study was carried out. Statistical analysis tests included Student's t-test and analysis of variance. Results: The prediction model indicated that in pessimistic conditions, the remaining shelf life was reduced to a merely 1 month following production (this is versus the 2 years expiration date given by manufacturer). However, the samples analyzed throughout a 6-month stability study revealed that storing CH solution at 4°C or 25°C does not produce any statistical difference regarding drug content, MIC, or sterility. Accelerated stability studies for 3 months period showed that only after 2 months from storage at 55°C the drug will start to degrade and a statistical difference could be observed. Conclusion: Storing CH-eye drops at room temperature for up to 6 months appears to have no effect on the stability of this antibiotic.","PeriodicalId":18106,"journal":{"name":"Libyan International Medical University Journal","volume":"3 1","pages":"42 - 48"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84138167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Sexual functions of female patients with chronic liver disease from two centers in Nigeria 尼日利亚两个中心慢性肝病女性患者的性功能

Libyan International Medical University Journal Pub Date : 2018-07-01 DOI: 10.4103/LIUJ.LIUJ_24_18

O. Adekanle, S. olowookere, O. Ijarotimi, D. Ndububa, O. Ayodeji

{"title":"Sexual functions of female patients with chronic liver disease from two centers in Nigeria","authors":"O. Adekanle, S. olowookere, O. Ijarotimi, D. Ndububa, O. Ayodeji","doi":"10.4103/LIUJ.LIUJ_24_18","DOIUrl":"https://doi.org/10.4103/LIUJ.LIUJ_24_18","url":null,"abstract":"Background: Chronic liver disease (CLD) is a disease with significant morbidity and mortality in Nigeria. This study assessed the sexual functions of women with chronic hepatitis B infection (CHB), liver cirrhosis (LC), and hepatocellular carcinoma (HCC) designated as cases and normal women as controls. Methods: A prospective, comparative, case–control study of CHB, LC, HCC, and controls. Consenting cases and controls completed a self-administered Female Sexual Function Questionnaire (FSFI). Bio-data was obtained for all participants and cases were graded using the Child–Turcotte–Pugh scores (CTP). Data obtained were entered into SPSS version 20 and analyzed using descriptive and inferential statistics. Results: A total of 176 women completed the study, comprising 88 cases and 88 controls. Mean age (standard deviation) was 39.5 + 8.5 years and 40.5 + 8.2 years for cases and controls, respectively. Cases comprised CHB – 46, LC – 25, and HCC – 17, and their CTP classes were CTP A, 54; CTP B, 22; and CTP C, 12. The FSFI scores for CHB compared with controls were not statistically significant in all domains of the FSFI. The FSFI scores for LC and HCC in all domains were statistically significant compared with controls. Total mean FSFI scores for cases in CTP Class C showed sexual dysfunction, where 13.6% of CLD and 6.8% of all participants had sexual dysfunction and none among the controls. Conclusions: Females with advanced CLD had sexual dysfunction. Sexual concerns of females with CLD should be inquired for and treated.","PeriodicalId":18106,"journal":{"name":"Libyan International Medical University Journal","volume":"11 1","pages":"59 - 64"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73484562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Is metabolic syndrome truly prevailing in nondiabetic Libyan women 代谢综合征真的在非糖尿病的利比亚妇女中普遍存在吗

Libyan International Medical University Journal Pub Date : 2018-07-01 DOI: 10.4103/liuj.liuj_39_18

M. Al-Mendalawi

引用次数: 0