{"title":"[Molecular diagnosis of HIV-1 infection: potential roles and applications].","authors":"F Coutlée","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Diagnostic tests for HIV-1 infection have allowed to reduce the transmission of this virus by blood transfusions. They have also allowed to offer prophylactic as well as therapeutic measures early in the infection. The laboratory diagnosis of HIV-1 infection relies mainly on serological testings. Seroconversion can be detected earlier than previous assays with the use of purified HIV antigens such as peptides or recombinant proteins. The low sensitivity level of p24 antigen detection can be improved by acid dissociation of immune complexes in serum samples. A promising method, the polymerase chain reaction (PCR) will facilitate the diagnosis of HIV infection for newborns from seropositive mothers. During PCR, a segment of the genome of HIV is amplified a million-fold and products of amplification are detected by specific probes. The status of individuals with indeterminate serology results could be clarified with PCR. It could also potentially allow the prospective follow-up of patients under therapy to detect viral resistance. The usefulness of this powerful technology in clinical medicine still needs to be determined for HIV-1 diagnosis.</p>","PeriodicalId":18049,"journal":{"name":"L'union medicale du Canada","volume":"123 6","pages":"348-58"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19078959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Baudelaire: a genius born of malediction].","authors":"R Henry","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18049,"journal":{"name":"L'union medicale du Canada","volume":"123 6","pages":"366-70"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19078849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Antihypertensive and anti-inflammatory, non-steroidal drugs: significant interactions?].","authors":"M M Perreault","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18049,"journal":{"name":"L'union medicale du Canada","volume":"123 6","pages":"343-6"},"PeriodicalIF":0.0,"publicationDate":"1994-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19078954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Chopin: a genius who lent himself but who never gave himself up].","authors":"R Henry","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18049,"journal":{"name":"L'union medicale du Canada","volume":"123 5","pages":"305-8"},"PeriodicalIF":0.0,"publicationDate":"1994-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19030722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Etymologic roots of medicine].","authors":"R Henry","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18049,"journal":{"name":"L'union medicale du Canada","volume":"123 5","pages":"304"},"PeriodicalIF":0.0,"publicationDate":"1994-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19030721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Laverdière, J Delorme, L Desrosiers, S Racine, P Boyle
{"title":"[Profile of microbiological analyses needed for hospitalized clients at the Maisonneuve-Rosemont hospital].","authors":"M Laverdière, J Delorme, L Desrosiers, S Racine, P Boyle","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>During five consecutive administrative periods, a computer data bank was set up from informations written on laboratory forms requesting tests in microbiology. A total of 13,260 forms were received and 11,591 were included in our study. 7,010 tests (60%) were requested from medical specialties; 40% of these tests were from patients admitted on hematology and on pediatrics wards. Of the 4,581 remaining tests, 36% were ordered for patients admitted on general surgery and on ophthalmology wards. Medical patients had three times as much blood cultures requested than surgical patients. The numbers of urine cultures done for medical and surgical patients were however similar (1,832 and 1,699 respectively). The average cost for microbiology cultures was twice as much in medical than in surgical patients. Such analysis of prescribing profile for laboratory tests provides useful information for the diagnosis related groups (DRG) system and can allow for a more efficient distribution of hospital resources.</p>","PeriodicalId":18049,"journal":{"name":"L'union medicale du Canada","volume":"123 5","pages":"297-9; 302-3"},"PeriodicalIF":0.0,"publicationDate":"1994-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19030720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J V Patenaude, P Couture, S Desmarais, R Lecours, M Lussier, D Q Nguyen, R Parent, P D'Amico
{"title":"[Principles of care of various arterial diseases. Part 2: acute arterial ischemia].","authors":"J V Patenaude, P Couture, S Desmarais, R Lecours, M Lussier, D Q Nguyen, R Parent, P D'Amico","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18049,"journal":{"name":"L'union medicale du Canada","volume":"123 5","pages":"suppl 1-32"},"PeriodicalIF":0.0,"publicationDate":"1994-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19030715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Antiviral agents: their proper use in immunodeficient patients].","authors":"M C Pineau","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18049,"journal":{"name":"L'union medicale du Canada","volume":"123 5","pages":"289-92"},"PeriodicalIF":0.0,"publicationDate":"1994-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19030717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}