{"title":"Pre-column Derivatization¸ Elution Order, Molecular Configuration and Green Chromatographic Separation of Diastereomeric Derivatives of β-Amino Alcohols","authors":"","doi":"10.33263/lianbs124.139","DOIUrl":"https://doi.org/10.33263/lianbs124.139","url":null,"abstract":"A green chromatographic method was developed for the indirect enantio-separation of racemic amino alcohols by introducing a micellar mobile phase for the HPLC. Here, cyanuric chloride-based activated chiral reagents were prepared, characterized, and used to derivatize racemic amino alcohols into diastereomeric derivatives. The chromatographic separation of the prepared diastereomeric derivatives was achieved on the C18 column of the RP-HPLC using a surfactant-based (Brij-35 + SDS) aqueous mobile phase (as an alternative to organic solvents). The impact of the varying concentration of surfactants in the mobile phase and pH of buffer on the chromatographic separation was optimized. Additionally, the DFT calculations were performed, and the absolute configurations and elution orders of the diastereomeric derivatives were investigated. Developed method’s robustness and selectivity was optimized by performing validation studies (LOD = 0.286 ng/mL; LOQ = 0.858 ng/mL). Also, the green assessment score was calculated for the developed method (84 scores; an excellent green method).","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79955332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Morphology and Anti-microbial Studies of Zinc Stannate Nanoparticles Constructed via Green Synthesis Approach","authors":"","doi":"10.33263/lianbs124.138","DOIUrl":"https://doi.org/10.33263/lianbs124.138","url":null,"abstract":"In the scientific field, microbial contaminations are growing along with the developments of newer research methodologies. Evaluating anti-microbial activity using newly designed materials has been gaining importance over the years to address this issue. The present work aims to form zinc stannate nanoparticles (ZTO NPs) through bio-synthesis and compare their biological efficiency with the as-synthesized nanoparticles through chemical synthesis. The nanoparticles (Zn2SnO4) were synthesized through a hydrothermal method by developing moderate experimental conditions. Three different combinations were synthesized using 2:1 mole ratio of ZnCl2 and SnCl2 precursors, and leaf extracts such as Aloe barbadensis mill and Terminalia catappa were used in the bio-synthesis method. Sodium hydroxide was used as a mineralizer in the chemical synthesis method. The obtained ZTO NPs were characterized by XRD, SEM-EDS, and UV-Visible spectral techniques. Finally, the antibacterial and anti-fungal activities were evaluated using the Agar-well diffusion method. Competitive biological activity response from the bio-synthesized ZTO NPs against the selected bacterial (Bacillus subtilis, S. Aureus, E. Coli, and P. Aeruginosa) and fungal strains (A. Niger and C. albicans). The synthesized ZTO NPs were highly efficient in exhibiting potential biological activity against the selected microbes.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76440341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comprehensive Review on the Antimicrobial and Photocatalytic Properties of Green Synthesized Silver Nanoparticles","authors":"","doi":"10.33263/lianbs124.140","DOIUrl":"https://doi.org/10.33263/lianbs124.140","url":null,"abstract":"With the advancement of technology, there is a growing demand for new nanoparticles that are viable, eco-friendly, non-toxic, and non-hazardous, as well as having unique chemical and physical properties. Silver nanoparticles are currently promising for antibacterial, antimicrobial, and photocatalytic applications. Because of their toxicity, nanosilver particles are now widely used in various applications, including cosmetics, clothing, sunscreen, medicinal, sensing, antibacterial, antimicrobial, and photocatalytic. The importance of plant extracts in the synthesis of AgNPs is emphasized. The various mechanisms and characterization techniques used in the study of silver nanoparticles will also be covered. This review also discusses the role of green synthesized AgNPs in antimicrobial and photocatalytic applications, which adds to our understanding of improving health, and the environment and preventing contagious diseases.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"11 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85721588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sorption Removal of Methylene Blue Dye from Aqueous Solution by Powdered Yellow Flame Tree Flower (Peltophorum pterocarpum)","authors":"","doi":"10.33263/lianbs124.135","DOIUrl":"https://doi.org/10.33263/lianbs124.135","url":null,"abstract":"Present study involves the biosorptive removal study of methylene blue, a blue cationic thiazine dye using Peltophorum pterocarpumflowers (PPF). The effect of parameters on dye removal, such as contact time, pH, adsorbent, and adsorbate concentrations, were examined. The results demonstrated that the optimal experimental conditions for the adsorption were attained at pH 9 and contact time at 40 minutes. The equilibrium data of adsorption isotherms were well fitted to the Langmuir model with maximum adsorption efficiency of 71.9434 mg/g. The pseudo-second-order model could well fit the adsorption kinetics. These results demonstrate that the PPF biomaterial has the potential in effective sorptive elimination of MB dye from aqueous solutions.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85929154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In vitro Virucidal Activity of Silver Nanoparticles against H1N1 Influenza A Virus and Herpes Simplex Virus-1","authors":"","doi":"10.33263/lianbs124.136","DOIUrl":"https://doi.org/10.33263/lianbs124.136","url":null,"abstract":"Silver nanoparticles (AgNPs) have provided a broad spectrum of antiviral activity against some types of enveloped and non-enveloped viruses. Silver nanoparticles are currently the most widely commercialized nanomaterials. In recent times, viral infections are emerging as one of the most common diseases with high mortality in the human population. The present study investigates the antiviral efficacy of the silver nanoparticles synthesized by the green method against HSV-1 and H1N1 influenza viruses. Characterization studies revealed that the silver nanoparticles showed an average particle size of 47 nm with a surface plasmon resonance peak at 426 nm. Silver nanoparticles exhibited 50% cytotoxicity in Vero cells at 197 µg/mL concentration, and 50% Inhibitory concentration (IC50) against HSV-1 was observed at 19.6 μg/mL. Silver nanoparticles demonstrated > 1 log reduction in H1N1 influenza A virus at 17 µg/mL. These findings indicate that silver nanoparticles possess excellent antiviral activity, which can be suitably used in various formulations to eradicate the spread of viral infections.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87232212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Organic Chromophores from D–π–A to D–A’–π–A: Influence of the Auxiliary Acceptor on Energy Levels, Molecular Absorption, and Nonlinear Optical Response","authors":"","doi":"10.33263/lianbs124.137","DOIUrl":"https://doi.org/10.33263/lianbs124.137","url":null,"abstract":"In this research article, four organic chromophores of type D–Ai–π–A (i=2–4) combining various auxiliary acceptors (Ai) with phenothiazine (PTZ) as the electron donor, thiophene as the π-conjugated bridge, and tricyanovinyl dihydrofuran (TCF) as the electron acceptor have been structured and theoretically studied using density functional theory (DFT) and time-dependent DFT (TD-DFT) methods. The effects of various auxiliary acceptors in D–Ai–π–A chromophores on the nonlinear optical (NLO) response have been examined. In this context, the geometric and electronic structures, intramolecular charge transfer (ICT), NBO analysis, absorption wavelength in different organic solvents, polarizability (α), and hyperpolarizability (β) have been determined. They have been assessed to predict the appropriate candidates for NLO material. The data obtained illustrate that all chromophores with various auxiliary acceptors present a large NLO response ranging from 13541.17 to 66723.38 (a.u), PTZ-2 especially with auxiliary acceptor 2,3-dimethylthieno[3,4-b]pyrazine presents the highest [(879.10 (a.u)) and βtot (66723.38 (a.u)] values. A strong NLO response indicates that this series of organic chromophores with a D-Ai-π-A architecture exhibits large first hyperpolarizability βtot values, which are much greater than those of urea.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86807681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physico-Chemical, Ultrasonic, and Structural Studies on Dextrin with alpha-Amylase in Aqueous Media At 298.15 K","authors":"","doi":"10.33263/lianbs124.141","DOIUrl":"https://doi.org/10.33263/lianbs124.141","url":null,"abstract":"The ultrasonic velocity, density, and viscosity of dextrin in an aqueous medium at 298.15 K were measured using -amylase in this study. The measured parameters were used to calculate acoustic/density parameters such as molar volume (Vm), isentropic compressibility (T), thermal expansion coefficient (T), relaxation time (t), relaxation strength (r), relative viscosity (r), Enthalpy (H), Activation Energy (G), Surface Tension (), van der Walls constant (b), molecular radius (r), Geometrical volume (B), molar surface area (Y), Collision factor (S). Different acoustic magnitudes are computed because they are important in researching unique chemical interactions and theoretical calculations.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82265040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Srivastava, S. Yadav, R. Chaubey, S. Ojha, A. Mishra, S. Mishra
{"title":"Herbal Immunomodulators: A Powerful Preventive Weapon for COVID-19","authors":"S. Srivastava, S. Yadav, R. Chaubey, S. Ojha, A. Mishra, S. Mishra","doi":"10.33263/lianbs124.134","DOIUrl":"https://doi.org/10.33263/lianbs124.134","url":null,"abstract":"The Corona Virus Disease of 2019 is characterized by a serious epidemic (COVID-19). The acute respiratory syndrome is caused by the coronavirus, which is followed by an inflammatory response in the host. Systemic inflammatory response syndrome (SIRS) is a condition in which the body causes acute breathing problems, multiple organ impairment disorder, and even in the early stages of multiple organ failure extreme COVID-19. Increased development of anti-inflammatory cytokines in the late stages of serious disease causes the immune system's reaction to becoming controlled, resulting in immune fatigue. Pandemics have wreaked havoc on humanity’s strata, wiped out whole nations, and strengthening immunity is long overdue. A strong immune system is needed to fight a viral infection. Multivitamin-rich diets improve pathogen immunity by triggering immune responses in several immune cells, as an example. Various immune-stimulating herbs, plants, and spices like chicory, Tinospora cordifolia, Withania somnifera, myrrh, ginger, etc., must be included to counteract the pathogens.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81867981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Performance Evaluation of Heat Pipe Heat Exchanger with Nanofluid: An Experimental Study","authors":"","doi":"10.33263/lianbs124.121","DOIUrl":"https://doi.org/10.33263/lianbs124.121","url":null,"abstract":"A heat pipe heat exchanger is fabricated and tested to recapture heat energy in low-temperature applications. The heat transfer fluid used has nanoparticles of zinc oxide suspended in water. The heat transmission performance of the arrangement is evaluated for variable heat supply at distinct mass flow rates. The mass flux for cold and hot air streams is changed for a specific heat input, and observations are recorded. The heat input values are incremented from 25 W to 1500 W while the flow rate of air is incremented from 0.047 to 0.236 m3/s. Maximum effectiveness of 0.28 is noted for heat input of 1500 W at a flow rate of 0.047 m3/s. The variation of heat transfer coefficient is studied for change in flow rate of air and source temperature of the air supplied. It is found that the coefficient of heat transfer increases with source temperature. The enhancement of performance is credited to better thermal conductivity due to the introduction of nanoparticles.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74358926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nano Adsorbents in Wastewater Treatment: A New Paradigm in Wastewater Management","authors":"","doi":"10.33263/lianbs124.125","DOIUrl":"https://doi.org/10.33263/lianbs124.125","url":null,"abstract":"Increasing water pollution has urged the need to elucidate more potent techniques for removing contaminants from wastewater 1 and groundwater. Numerous techniques or processes have been explored and designed for water purification. Amongst all other water/wastewater remediation techniques, nanotechnology has gained wider attention in water remediation via numerous mechanisms, such as the adsorption of heavy metals and the removal of pathogens. Nanoadsorbent materials have emerged as a promising solution for solving this crucial environmental issue. Their unique chemical and physical properties, such as higher ranking, quality, and status, promote their application compared to traditional adsorbents. Recent research studies have reported their promising potential in water treatment, including polymeric, carbon, tubezeolites, and metal nanosorbents. Hence, this review mainly aims to provide summarized data presenting all the beneficial aspects of nanosorbents in wastewater/water remediation.","PeriodicalId":18009,"journal":{"name":"Letters in Applied NanoBioScience","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84060928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}