Langenbecks Archiv fur Chirurgie最新文献

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[Artificial pressure increase in subcutaneous abscess with evidence of general systemic reaction]. [皮下脓肿人工加压,全身反应的证据]。
Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01 DOI: 10.1007/s004230050069
P Bertram, K H Treutner, B Klosterhalfen, G Arlt, M Anurov, M Polivoda, A Ottinger, V Schumpelick
{"title":"[Artificial pressure increase in subcutaneous abscess with evidence of general systemic reaction].","authors":"P Bertram,&nbsp;K H Treutner,&nbsp;B Klosterhalfen,&nbsp;G Arlt,&nbsp;M Anurov,&nbsp;M Polivoda,&nbsp;A Ottinger,&nbsp;V Schumpelick","doi":"10.1007/s004230050069","DOIUrl":"https://doi.org/10.1007/s004230050069","url":null,"abstract":"<p><p>Abscess is customarily thought of as a collection of a large number of microorganisms, inflammatory cells and necrotic debris separated from the surrounding tissue by a fibrous capsule. Modern work focussed attention on more physico-chemical parameters in abscess pathogenesis. Recent experiences from animal models underline the impact of abscess pressure and bio-physicochemical parameters in the \"abscess compartment\" for systemic spreading. Artificial raising of abscess-pressure in pigs up to 80 mmHg was followed by increase of temperature and heartbeat rate and decrease of median arterial pressure. Elevated levels of TNF alpha, IL-1 and positive blood cultures support the theory of abscess pressure as a most important variable in abscess formation. We conclude that abscess pressure may play a pivotal role in systemic spreading of the primarily localized process.</p>","PeriodicalId":17985,"journal":{"name":"Langenbecks Archiv fur Chirurgie","volume":"382 6","pages":"291-4"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20421119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Detection of circulating albumin-mRNA by RT-PCR does not indicate metastasizing hepatocellular carcinoma. RT-PCR检测循环白蛋白mrna不能提示肝细胞癌转移。
Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01 DOI: 10.1007/BF02465094
U Leonhardt, U Ritzel, M Ottleben, A Vignoli, G Ramadori
{"title":"Detection of circulating albumin-mRNA by RT-PCR does not indicate metastasizing hepatocellular carcinoma.","authors":"U Leonhardt,&nbsp;U Ritzel,&nbsp;M Ottleben,&nbsp;A Vignoli,&nbsp;G Ramadori","doi":"10.1007/BF02465094","DOIUrl":"https://doi.org/10.1007/BF02465094","url":null,"abstract":"<p><p>Hepatocellular carcinomas (HCC) frequently recur after partial liver resection or orthotopic liver transplantation, possibly because of the presence of a small number of hepatoma cells in the peripheral blood. Detection of circulating HCC cells might improve therapeutic options and could predict disease recurrence resulting from a metastasizing disease. In the present study, human albumin-mRNA was detected by RT-PCR in the peripheral blood of patients with hepatocellular carcinoma. Circulating albumin-specific PCR products were detected in each patient with HCC, but also in healthy volunteers. It is concluded that albumin-mRNA is not specific to circulating hepatoma cells and therefore does not indicate metastasizing disease.</p>","PeriodicalId":17985,"journal":{"name":"Langenbecks Archiv fur Chirurgie","volume":"382 2","pages":"83-6"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02465094","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20077134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
[Benign symmetrical lipomatosis. A therapeutic dilemma?]. 良性对称脂肪瘤病。治疗困境?
Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01
J Sehouli, D Stengel, H Schauwecker
{"title":"[Benign symmetrical lipomatosis. A therapeutic dilemma?].","authors":"J Sehouli, D Stengel, H Schauwecker","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Benign symmetric lipomatosis (BSL), also known as Madelung's disease, is a rare condition and characterized by diffuse but painless growth of unencapsulated lipomas. A close correlation to alcohol and nicotine abuse, metabolic disturbances and malignant tumours have been observed. Surgical treatment is frequently followed by recurrence, nevertheless, it can yield satisfactory functional and cosmetic results. A case of BSL with uncommonly distributed tumors is reported.</p>","PeriodicalId":17985,"journal":{"name":"Langenbecks Archiv fur Chirurgie","volume":"382 5","pages":"271-3"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20339179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Behavior of postoperative adhesions after intraperitoneal administration of fibrinolytic drugs in a rat model]. [大鼠模型腹腔注射纤溶药物术后粘连行为]。
Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01
A Stapel, N Geissler, B Mlasowsky, D Jung
{"title":"[Behavior of postoperative adhesions after intraperitoneal administration of fibrinolytic drugs in a rat model].","authors":"A Stapel, N Geissler, B Mlasowsky, D Jung","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a rat model, the effect of the intraperitoneal application of fibrinolytic agents on the development of adhesions was examined. Streptokinase and TPA reduced sero-serosal adhesions significantly, whereas urokinase did not reduce them. Intravascular coagulation was not affected.</p>","PeriodicalId":17985,"journal":{"name":"Langenbecks Archiv fur Chirurgie","volume":"382 1","pages":"33-6"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20104847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Diaphragm replacement. An animal experiment study]. (隔膜替换。[动物实验研究]。
Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01
G Steinau, B Dreuw, J Schleef, V Schumpelick
{"title":"[Diaphragm replacement. An animal experiment study].","authors":"G Steinau, B Dreuw, J Schleef, V Schumpelick","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Only a few indications exist for diaphragm replacement: aplasias, tumours and accidents. The defect may be so extensive that it is impossible to close the gap. Allogenic and autologous materials are proposed for replacement of the diaphragm. The disadvantages of allogenic materials are recurrence rates of up to 20% and a high rate of malalignment of thoracic muscles and bones; the implication of autologous materials requires a longer operation time and no long-term results exist. To avoid these disadvantages, we have tested a material from bovine serosa, which is absorbable for a short time, for diaphragm replacement.</p><p><strong>Methods: </strong>The merits of four methods of diaphragmatic hernia repair were evaluated in animals. One hundred Sprague-Dawley rats underwent laparotomy. The control group had an incision in the diaphragm with primary repair. The other four groups underwent partial resection of the left hemidiaphragm. The defects were repaired in 20 rats with lyophilized dura, in 20 with polytetrafluoroethylene (PTFE), in 20 with autologous transversus muscle and in another 20 with absorbable serosa from a cow. The animals were followed up by electromyography (EMG) and post-mortem physical and histological examinations after 3 and 6 months.</p><p><strong>Results: </strong>Eighty-nine animals survived the operations. The EMG showed normal function for the absorbable material and the transversus muscle. Only scanty physiological waves were recorded in the PTFE group. The examination for stretching and stress showed good results for all materials tested. The histological examinations showed strong foreign body reactions in the dura and PTFE groups. The absorbable bovine serosa had vanished after 3 months postoperatively.</p><p><strong>Conclusion: </strong>We conclude that bovine serosa can be recommended for the treatment of diaphragmatic defects.</p>","PeriodicalId":17985,"journal":{"name":"Langenbecks Archiv fur Chirurgie","volume":"382 2","pages":"74-8"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20143950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Induction of heat shock protein 70 (HSP70) by zinc bis (DL-hydrogen aspartate) reduces ischemic small-bowel tissue damage in rats. 双氧化锌(dl -天冬氨酸氢)诱导热休克蛋白70 (HSP70)可减轻大鼠缺血性小肠组织损伤。
Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01 DOI: 10.1007/BF02539308
C Töns, B Klosterhalfen, H M Klein, H M Rau, M Anurov, A Oettinger, V Schumpelick
{"title":"Induction of heat shock protein 70 (HSP70) by zinc bis (DL-hydrogen aspartate) reduces ischemic small-bowel tissue damage in rats.","authors":"C Töns,&nbsp;B Klosterhalfen,&nbsp;H M Klein,&nbsp;H M Rau,&nbsp;M Anurov,&nbsp;A Oettinger,&nbsp;V Schumpelick","doi":"10.1007/BF02539308","DOIUrl":"https://doi.org/10.1007/BF02539308","url":null,"abstract":"<p><p>The aim of the study was to determine whether the induction of HSP70 by Zn2+ is able to protect the small bowel of rats against ischemia. Twenty-four male Wistar rats (weight 200-300 g) were divided into four groups: (1) saline treatment for 24 h (n = 4); (2) Zn2+ treatment for 24 h (n = 4); (3) Saline pretreatment for 24 h and ischemia (n = 8); (4) Zn2+ pretreatment for 24 h and ischemia (n = 8). Pretreatment with Zn2+ was carried out by intraperitoneal administration of 50 mg/kg zinc bis (DL-hydrogen aspartate) = 10 mg/kg Zn2+. Ischemia in a defined segment of the small bowel was produced by ligation of the mesenteric vein and artery and ligation of both ends of the segment. Tissue samples were collected before and 2, 4 and 6 h after ligation and investigated by histology, immunohistochemistry and Western blotting. Twenty-four h after i.p. Zn2+ injection, the small bowel expressed increased HSP70 tissue levels. Histology with subsequent grading of ischemic tissue injury showed significantly decreased tissue necrosis after Zn2+ pretreatment and HSP70 induction compared with saline pretreated controls. In conclusion, this study proves that Zn2+ is inducing HSP70 in the small bowel in vivo and hereby able to protect the small bowel against ischemia.</p>","PeriodicalId":17985,"journal":{"name":"Langenbecks Archiv fur Chirurgie","volume":"382 1","pages":"43-8"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02539308","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20007679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
[Gardner syndrome and thyroid gland carcinoma]. [加德纳综合征和甲状腺癌]。
Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01 DOI: 10.1007/BF02465088
G Möslein
{"title":"[Gardner syndrome and thyroid gland carcinoma].","authors":"G Möslein","doi":"10.1007/BF02465088","DOIUrl":"https://doi.org/10.1007/BF02465088","url":null,"abstract":"","PeriodicalId":17985,"journal":{"name":"Langenbecks Archiv fur Chirurgie","volume":"382 2","pages":"59-60"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02465088","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20144657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Improving anal continence by selective stimulation of the external anal sphincter muscle]. 选择性刺激肛门外括约肌改善肛门失禁。
Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01 DOI: 10.1007/s004230050073
D Lorenz, M Karaorman, G Wipfler, P Jünemann, A Richter, B Rumstadt
{"title":"[Improving anal continence by selective stimulation of the external anal sphincter muscle].","authors":"D Lorenz,&nbsp;M Karaorman,&nbsp;G Wipfler,&nbsp;P Jünemann,&nbsp;A Richter,&nbsp;B Rumstadt","doi":"10.1007/s004230050073","DOIUrl":"https://doi.org/10.1007/s004230050073","url":null,"abstract":"<p><p>Using the pig as a model, it was shown that stimulation of the distal nerve ending of the pudendal nerve leads to the isolated stimulation of the external anal sphincter muscle. No difference in pressure response was noted after application of between 0.5 and 1.5 mA unilateral or bilateral stimulation. Major advantages observed using between 1.5 and 2.5 mA bilateral stimulation; with a stimulation between 2.0 and 2.5 mA the pressure response was twice as high compared to unilateral stimulation. Continuous stimulation of the striated anal sphincter muscle leads to fatigue, reaching 50% fatigue after a median time between 40-90 s. In cyclic stimulation (alternation every 15 s, duration 20 min) a fatigue reaction was also seen. The peak pressure decreased after 20 min for a median of 11%, the final pressure was lowered in 15% following a logarithmic curve pattern. The experimental application of variable impulse ranges also caused pressure differences. Increasing the impulse range from 200 to 450 microseconds (peak pressure) vs. 400 microseconds (final pressure) resulted in a statistically significant pressure increase. Therefore, it was proven that selective stimulation of the external anal sphincter muscle can lead to a transient pressure increase, which possibly improves fecal continence.</p>","PeriodicalId":17985,"journal":{"name":"Langenbecks Archiv fur Chirurgie","volume":"382 6","pages":"311-8"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20421123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[1996 pathogen incidence and resistance status in peritonitis]. [1996]腹膜炎病原菌发病率及耐药性现状。
Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01 DOI: 10.1007/pl00014636
J Focht, K Nösner
{"title":"[1996 pathogen incidence and resistance status in peritonitis].","authors":"J Focht,&nbsp;K Nösner","doi":"10.1007/pl00014636","DOIUrl":"https://doi.org/10.1007/pl00014636","url":null,"abstract":"<p><p>Severe intra-abdominal infection is associated with a high mortality rate. In addition to risk factors in the patients, the causal pathogens and the selection of appropriate therapeutic procedures play an essential part in the course of these conditions. In the majority of intra-abdominal infections mixed aerobic/anaerobic infections, mostly with some involvement of enterobacteria and also of enterococci and staphylococci can be demonstrated. In addition to surgical intervention a calculated antimicrobial initial treatment of intra-abdominal infections with an antibiotic with an adequate effect to combat the pathogen concerned can contribute to improving the patient's prognosis. A calculated antibiotic treatment can only be effectively and reliably carried through if the frequency of the pathogen and the resistance situation are known. Retrospective evaluations of data on the sensitivity and frequency of pathogens from a defined group of subjects allow conclusions on the epidemiological situation in a particular catchment area or in a medical sector and thus make it possible to calculate the appropriate therapy for infections. In 1996 a total of 2,779 bacterial isolates from the intra-abdominal infection sector were examined: 935 Enterobacteriaceae, 83 nonfermenters, 177 Staphylococcus spp., 211 Enterococcus spp., 39 Streptococcus spp., and 1334 different anaerobic bacteria. Fresh clinical isolates were available for all pathogens tested. The most frequent gram-negative pathogen was E. coli (60%) and the most frequent gram-positive pathogen, E. faecalis (44%); the most frequent anaerobic pathogen was B. fragilis (39%). Taurolodine had the lowest resistance rate against gram-negative and anaerobic pathogens. Teicoplanin had the highest activity against gram-positive pathogens.</p>","PeriodicalId":17985,"journal":{"name":"Langenbecks Archiv fur Chirurgie","volume":"382 4 Suppl 1","pages":"S1-4"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/pl00014636","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20267718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
[Benign symmetrical lipomatosis. A therapeutic dilemma?]. 良性对称脂肪瘤病。治疗困境?
Langenbecks Archiv fur Chirurgie Pub Date : 1997-01-01 DOI: 10.1007/S004230050065
J. Sehouli, D. Stengel, H. Schauwecker
{"title":"[Benign symmetrical lipomatosis. A therapeutic dilemma?].","authors":"J. Sehouli, D. Stengel, H. Schauwecker","doi":"10.1007/S004230050065","DOIUrl":"https://doi.org/10.1007/S004230050065","url":null,"abstract":"","PeriodicalId":17985,"journal":{"name":"Langenbecks Archiv fur Chirurgie","volume":"1 1","pages":"271-3"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83157672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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