Laser therapy最新文献

{"title":"Obituary of Great Teacher, Prof. Kazuhiko Atsumi","authors":"N. Nimsakul","doi":"10.5978/islsm.20-ob-01","DOIUrl":"https://doi.org/10.5978/islsm.20-ob-01","url":null,"abstract":"","PeriodicalId":17981,"journal":{"name":"Laser therapy","volume":"29 1","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71154367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravenous Laser Wavelength Irradiation Effect on Interleukins: IL-1α, IL-1β, IL6 in Diabetic Rats.","authors":"A Amjadi,&nbsp;H Mirmiranpor,&nbsp;S Khandani,&nbsp;S O Sobhani,&nbsp;Y Shafaee","doi":"10.5978/islsm.19-OR-18","DOIUrl":"https://doi.org/10.5978/islsm.19-OR-18","url":null,"abstract":"<p><strong>Background and aims: </strong>The main purpose of this investigation in Low-Level Laser Therapy (LLLT) on diabetic rats is laser wavelength effect on interleukins: IL-1α, IL-1β, IL6.</p><p><strong>Materials subjects and methods: </strong>At first, diabetes was induced in Wistar rats by streptozotocin (STZ) injection. Then, by intravenous laser therapy, the rats were irradiated by four continuous wave lasers: IR (λ = 808 nm), Red (λ = 638 nm), Green (λ = 532 nm) and Blue (λ= 450 nm) to compare the related laser wavelength effect on different interleukins. The inflammatory parameters were measured 2,6 and 24 hours after laser therapy from blood samples and plotted for different laser wavelengths.</p><p><strong>Results: </strong>The results show a decrease in all the above parameters by different laser irradiation in comparison to non-radiated diabetic control ones. More importantly with constant laser energy as the laser wavelength decreases, it affects more efficiently on lowering the above parameters.</p><p><strong>Conclusions: </strong>we can conclude from our data on diabetic rats that in intravenous LLLT, with constant laser energy, shorter wavelengths like Blue (λ= 450 nm) is more effective than longer wavelengths such as Red (λ = 638 nm) and IR (λ = 808 nm) lasers to lower the level of interleukins toward non-diabetic ones.</p>","PeriodicalId":17981,"journal":{"name":"Laser therapy","volume":"28 4","pages":"267-273"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5978/islsm.19-OR-18","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37808833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Goodbye Boar, Hello Rat!","authors":"Toshio Ohshiro","doi":"10.5978/islsm.19-ED-04","DOIUrl":"https://doi.org/10.5978/islsm.19-ED-04","url":null,"abstract":"","PeriodicalId":17981,"journal":{"name":"Laser therapy","volume":"28 4","pages":"241-244"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087336/pdf/islsm-28-241.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37808427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydrogen peroxide penetration into the pulp chamber during conventional in-office bleaching and diode laser-assisted bleaching with three different wavelengths.","authors":"Mahdi Abbasi, Edris Pordel, Nasim Chiniforush, Sattar Gorgani Firuzjaee, Ladan Ranjbar Omrani","doi":"10.5978/islsm.19-OR-20","DOIUrl":"10.5978/islsm.19-OR-20","url":null,"abstract":"<p><strong>Background and aims: </strong>Penetration of hydrogen peroxide into the pulp chamber and subsequent tooth hypersensitivity is a common concern in dental bleaching. The aim of this study was to assess the penetration of hydrogen peroxide (H₂O₂) into the pulp chamber in diode-laser activated bleaching with different laser wavelengths.</p><p><strong>Materials and methods: </strong>Fifty extracted human maxillary anterior teeth were collected and divided into five groups(n = 10). Group 1: conventional in-office bleaching using Opalescence Boost gel. Group 2: Bleaching with Biolase Laser White 20 gel activated by 980 nm diode laser. Group 3: Bleaching with Biolase Laser White 20 gel activated by 810 nm diode laser. Group 4: Bleaching with Biolase Laser White 20 gel activated by 940 nm diode laser. Group 5: No bleaching control group.After bleaching, the solution into the pulp chamber was collected and analyzed using a spectrophotometer. The recorded data were compared with a standard sample and the results were analyzed and compared using one-way ANOVA and Tukey's HSD tests.</p><p><strong>Results: </strong>In all bleached groups, H₂O₂ had infiltrated into the pulp chamber. The highest level of penetration was noted in group 2 (2.32 ± 0.25 µg), while the lowest level was noted in group 3 (1.85 ± 0.33 µg). The difference in this regard was significant between groups 2 and 3 (P = 0.024), but the differences between other groups were not statistically significant (P ≥ 0.42).</p><p><strong>Conclusion: </strong>Considering the results of this study, it can be stated that hydroge peroxide penetration in to pulp chamber in diode laser activation of bleaching agent according to manufactures instruction is not higher than in-office bleaching. The wavelength of diode laser had significant effect on penetration of hydrogen peroxide into pulp chamber.</p>","PeriodicalId":17981,"journal":{"name":"Laser therapy","volume":"28 4","pages":"285-290"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5978/islsm.19-OR-20","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37808835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of 830 nm low-power laser irradiation on body weight gain and inflammatory cytokines in experimental diabetes in different animal models.","authors":"Ujjal K Bhawal, Kiyomi Yoshida, Takashi Kurita, Masatoshi Suzuki, Yuichiro Okada, Nitesh Tewari, Shunichi Oka, Noboru Kuboyama, Koichiro Hiratsuka","doi":"10.5978/islsm.19-OR-17","DOIUrl":"10.5978/islsm.19-OR-17","url":null,"abstract":"<p><strong>Background and aims: </strong>The present investigation was carried out to determine the levels of blood serum components and inflammatory cytokines in diabetic rat models [Goto-Kakizaki (GK), Zucker, and streptozotocin (STZ)-induced Sprague Dawley (SD) rats] which underwent abdominal Low-Power Laser Irradiation (LPLI) and compare them with non-irradiated controls.</p><p><strong>Methods: </strong>The animals were subdivided into the following groups: diabetic control rats (GK, Zucker, STZ) and diabetic rats treated with LPLI (GK + LPLI, Zucker + LPLI, and STZ + LPLI) (n = 7). The animals were irradiated three times weekly for 12 weeks in LPLI (830 nm) at a dose of 5 J/cm² for 500 s.</p><p><strong>Results: </strong>Body weight was significantly lowered in the Zucker- LPLI group compared to control at 10 weeks and this pattern was maintained until 12 weeks of age. TNF-α, IL-1I and IL-6 levels were significantly decreased (5.1 ± 1.1 vs 3.3 ± 0.5, p < 0.01; 43.6 ± 8.8 vs 27.1 ± 3.8, p < 0.01; 98.3 ± 15.8 vs 62.2 ± 12.1, p < 0.01) in the Zucker- LPLI group compared with the control rats. The small intestinal transit rates of charcoal meals were significantly decreased (58.1 ± 10.1 vs 73.4 ± 13.3, p < 0.05) in the Zucker-LPLI group compared with the control rats. Similarly, the serum levels of glucose, cholesterol and triglycerides of LPLI groups were decreased in comparison with that of diabetic control rats.</p><p><strong>Conclusions: </strong>We suggest that abdominal LPLI can reduce body weight and LPLI could be applicable for use against diabetic-induced inflammatory factors.</p>","PeriodicalId":17981,"journal":{"name":"Laser therapy","volume":"28 4","pages":"257-265"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087339/pdf/islsm-28-257.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37808832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photodynamic therapy by lysosomal-targeted drug delivery using talaporfin sodium incorporated into inactivated virus particles.","authors":"Sharmin Akter, Mizuho Inai, Sachiko Saito, Norihiro Honda, Hisanao Hazama, Tomoyuki Nishikawa, Yasufumi Kaneda, Kunio Awazu","doi":"10.5978/islsm.19-OR-11","DOIUrl":"10.5978/islsm.19-OR-11","url":null,"abstract":"<p><strong>Background: </strong>Photodynamic therapy (PDT), a minimally invasive cancer treatment involving the activation of photosensitizer by a specific wavelength of light, is considered to be a promising treatment option for drug-resistant prostate cancer. Hemagglutinating virus of Japan envelope (HVJ-E) has the potential to serve as a highly effective cancer therapy through selective drug delivery and enhancement of the anti-tumor immune response.</p><p><strong>Objectives: </strong>To improve therapeutic efficacy and selective accumulation of photosensitizer into tumor cells, we developed a novel photosensitizer, Laserphyrin^®-HVJ-E (L-HVJ-E), by incorporating talaporfin sodium (Laserphyrin^®, Meiji Seika Pharma) into HVJ-E.</p><p><strong>Materials and methods: </strong>The therapeutic effect of PDT with Laserphyrin^® or L-HVJ-E was evaluated in the human prostate cancer cell line PC-3 <i>in vitro</i>. The subcellular localizations of Laserphyrin^® and L-HVJ-E were observed by confocal microscopy. Apoptosis or necrosis following PDT was detected by annexin V-fluorescein/propidium iodide double staining.</p><p><strong>Results: </strong>The cytotoxic effect of Laserphyrin^®- and L-HVJ-E-mediated PDT were determined by evaluating cell survival rate and production of reactive oxygen species. The cytotoxicity of L-HVJ-E-mediated PDT was dependent on drug concentration and light dose. Laserphyrin^® and L-HVJ-E gradually entered cells as incubation time increased, and both agents tended to be distributed in lysosomes rather than mitochondria. Time and dose dependent increase in ROS production was observed, and induction of both apoptotic and necrotic cell death was confirmed.</p><p><strong>Conclusions: </strong>Laserphyrin^® and L-HVJ-E were distributed mainly in lysosomes and induced cell death by both apoptosis and necrosis. Furthermore, L-HVJ-E-mediated PDT effectively killed cultured PC-3 cells and exerted higher photocytotoxicity than Laserphyrin^®-mediated PDT.</p>","PeriodicalId":17981,"journal":{"name":"Laser therapy","volume":"28 4","pages":"245-256"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087334/pdf/islsm-28-245.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37808428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective management of focal reactive gingival overgrowths by diode laser: A review and report of two cases.","authors":"Madhu S Ratre,&nbsp;Pratik A Chaudhari,&nbsp;Shaleen Khetarpal,&nbsp;Pratiksha Kumar","doi":"10.5978/islsm.19-CR-03","DOIUrl":"https://doi.org/10.5978/islsm.19-CR-03","url":null,"abstract":"<p><strong>Background: </strong>Focal reactive gingival overgrowths (FRGO) are a common observation in a clinical dental practice that may occur in response to external and internal chronic stimuli in form of fibrous connective tissue lesions in the oral mucosa. Gingiva is the most commonly involved site of oral reactive lesions. For the confirmed diagnosis of FRGO not only clinical, but the histopathological presentation of the lesion plays a vital role. Various surgical treatment modalities like a scalpel, cryosurgery, electrosurgery, and lasers have been applied in the management of FRGO. The laser is new treatment modality being employed for treatment of FRGO.</p><p><strong>Case report: </strong>The purpose of this paper is to attempt short review on FRGO with the management of FRGO using diode laser. Here, we present effective management of peripheral giant cell granuloma and peripheral ossifying fibroma using diode laser. The follow-up of 01year showed no recurrence in both the cases.</p><p><strong>Conclusions: </strong>Diode soft tissue laser has added advantages like a bloodless surgical field, reduced bacteremia, minimal intra and postoperative discomfort over conventional modalities. Thus it is highly effective in the surgical management of FRGO.</p>","PeriodicalId":17981,"journal":{"name":"Laser therapy","volume":"28 4","pages":"291-297"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5978/islsm.19-CR-03","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37808836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of combined corticotomy and low level laser therapy on the rate of orthodontic tooth movement: split mouth randomized clinical trial.","authors":"Karim A Farid,&nbsp;Ahmed A Eid,&nbsp;Mohammed A Kaddah,&nbsp;Foad A Elsharaby","doi":"10.5978/islsm.19-OR-19","DOIUrl":"https://doi.org/10.5978/islsm.19-OR-19","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to evaluate the combined effect of corticotomy and Low-Level Laser Therapy(LLLT) on the rate of orthodontic tooth movement.</p><p><strong>Methods: </strong>A randomized split-mouth design for 16 female patients compared the rate of maxillary canine retraction using corticotomy combined with LLLT versus corticotomy only. The device used in the present study was an In-Ga-As semiconductor diode laser emitting at 940 nm (IR) with these parameters: 0.5 W/ cm² power density, 5 J/cm² Fluence, CW, 240 sec time irradiation, weekly for the first month and twice monthly for the next three months. Assessment of the rate of canine retraction was carried out via a series of dental models.</p><p><strong>Results: </strong>A non-significant statistical rate of canine retraction was achieved by LLLT combined to corticotomy compared with the corticotomy technique alone.</p><p><strong>Conclusion: </strong>Low-Level Laser Therapy combined to corticotomy could not achieve a higher rate of canine retraction compared to the golden standard corticotomy technique alone. No long-term adverse effects on the alveolar mucosa were detected following both techniques.</p>","PeriodicalId":17981,"journal":{"name":"Laser therapy","volume":"28 4","pages":"275-283"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5978/islsm.19-OR-19","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37808834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Exposures of volunteers to polychromatic light (480-3400 nm) trigger systemic mechanism of the human myeloma cells growth delay without any effect on bortezomib cytotoxicity in vitro.","authors":"Natalia V Kalmykova,&nbsp;Anna V Shcherbanyuk,&nbsp;Sergei I Moiseev,&nbsp;Natalia V Bichkova,&nbsp;Natalia I Davidova,&nbsp;Kira A Samoilova","doi":"10.5978/islsm.28_19-OR-12","DOIUrl":"https://doi.org/10.5978/islsm.28_19-OR-12","url":null,"abstract":"<p><strong>Background and aim: </strong>Polychromatic light is actively used in medicine. However, its oncological safety and effect against cytotoxic therapy remains poorly studied. Multiple myeloma (MM) develops in the bone marrow and therefore malignant plasma cells are inaccessible to direct exposure to light. The aim of our work was to study the influence of polychromatic visible and infra-red light (pVIS + pIR) on growth and sensitivity of the myeloma cells to the cytotoxic effect of drug bortezomib (BTZ) through systemic mechanism.</p><p><strong>Materials and methods: </strong>We explored the effect of volunteers blood sera after their 4-daily irradiations with pVIS + pIR light (480-3400 nm) on growth and viability of the human myeloma RPMI 8226 cells in the presence of BTZ at its application in 2 modes: short-term (1 h, 300 nM) and long-term ( 96 h, 5 nM). Viability and proliferative activity of cells was evaluated by MTT assay.</p><p><strong>Results: </strong>It was found that photomodified blood sera delayed growth of myeloma RPMI 8226 cells (by 25 % in 48 h and 23 % in 96 h) but had no effect on spontaneous and mitogen-induced proliferation of autologous peripheral blood T- and B-lymphocytes. We also revealed that pVIS + pIR did not change RPMI 8226 cells sensitivity to BTZ.</p><p><strong>Conclusion: </strong>The results suggest the systemic mechanism of polychromatic light and argue in favor of its oncological safety during/after BTZ therapy of MM patients without effect on the drug cytotoxicity.</p>","PeriodicalId":17981,"journal":{"name":"Laser therapy","volume":"28 3","pages":"164-170"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923347/pdf/islsm-28-164.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37602804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photobiomodulation guided healing in a sub-critical bone defect in calvarias of rats.","authors":"Angela Maria Paiva Magri,&nbsp;Kelly Rossetti Fernandes,&nbsp;Hueliton Wilian Kido,&nbsp;Gabriela Sodano Fernandes,&nbsp;Stephanie de Souza Fermino,&nbsp;Paulo Roberto Gabbai-Armelin,&nbsp;Franscisco José Correa Braga,&nbsp;Cintia Pereira de Góes,&nbsp;José Lucas Dos Santos Prado,&nbsp;Renata Neves Granito,&nbsp;Ana Claudia Muniz Rennó","doi":"10.5978/islsm.28_19-OR-13","DOIUrl":"https://doi.org/10.5978/islsm.28_19-OR-13","url":null,"abstract":"<p><strong>Background: </strong>Photobiomodulation presents stimulatory effects on tissue metabolism, constituting a promising strategy to produce bone tissue healing.</p><p><strong>Objective: </strong>the aim of the present study was to investigate the in vivo performance of PBM using an experimental model of cranial bone defect in rats.</p><p><strong>Material and methods: </strong>rats were distributed in 2 different groups (control group and PBM group). After the surgical procedure to induce cranial bone defects, PBM treatment initiated using a 808 nm laser (100 mW, 30 J/cm², 3 times/week). After 2 and 6 weeks, animals were euthanized and the samples were retrieved for the histopathological, histomorphometric, picrosirius red staining and immunohistochemistry analysis.</p><p><strong>Results: </strong>Histology analysis demonstrated that for PBM most of the bone defect was filled with newly formed bone (with a more mature aspect when compared to CG). Histomorphomeric analysis also demonstrated a higher amount of newly formed bone deposition in the irradiated animals, 2 weeks post-surgery. Furthermore, there was a more intense deposition of collagen for PBM, with ticker fibers. Results from Runx-2 immunohistochemistry demonstrated that a higher immunostaining for CG 2 week's post-surgery and no other difference was observed for Rank-L immunostaining.</p><p><strong>Conclusion: </strong>This current study concluded that the use of PBM was effective in stimulating newly formed bone and collagen fiber deposition in the sub-critical bone defect, being a promising strategy for bone tissue engineering.</p>","PeriodicalId":17981,"journal":{"name":"Laser therapy","volume":"28 3","pages":"171-179"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5978/islsm.28_19-OR-13","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37602805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}