Leber, Magen, Darm最新文献

[Diagnosis and therapy of Helicobacter pylori infection. Guidelines of the German Society of Digestive and Metabolic Diseases. Working Group of the German Society of Digestive and Metabolic Diseases]. 幽门螺杆菌感染的诊断与治疗。德国消化和代谢疾病学会指南。德国消化和代谢疾病学会工作组]。

Leber, Magen, Darm Pub Date : 1996-11-01

W F Caspary, R Arnold, E Bayerdörffer, R Behrens, B Birkner, B Braden, W Domschke, J Labenz, S Koletzko, P Malfertheiner, H Menge, W Rösch, W Schepp, M Strauch, M Stolte

引用次数: 0

[Positive effect of ursodeoxycholic acid on liver enzymes in autoimmune hepatitis with little activity--a pilot study]. [熊去氧胆酸对自身免疫性肝炎肝酶活性的积极作用——一项初步研究]。

Leber, Magen, Darm Pub Date : 1996-11-01

P Janowitz, W Kratzer, J G Wechsler

{"title":"[Positive effect of ursodeoxycholic acid on liver enzymes in autoimmune hepatitis with little activity--a pilot study].","authors":"P Janowitz, W Kratzer, J G Wechsler","doi":"","DOIUrl":"","url":null,"abstract":"In a pilot study we investigated the effect of ursodeoxycholic acid therapy in 11 patients (mean age 45.8 +/- 13.2 years) with chronic active, ANA- and/or SMA-positive autoimmune hepatitis of moderate severity. All patients were clinical asymptomatic and no indication for immunosuppressive therapy could be established in any patient. After a washout period of at least 3 months, the treatment was administrated with 500 mg ursodeoxycholic acid twice daily. A statistically significant improvement in all important hepatic parameters was achieved within 3 months of therapy. No further improvement could be observed once 6 months had elapsed. Significant decreases of SGOT (29.9 +/- 20.2 vs 17.7 +/- 7.1 U/l, p = 0.020), SGPT (43.8 +/- 31.0 vs. 19.6 +/- 6.7 U/l, p = 0.0012), GLDH (20.1 +/- 20.9 vs. 5.2 +/- 2.6 U/l, p = 0.0001) und gamma-GT (152.0 +/- 124.8 vs. 60.6 +/- 49.2 U/l, p = 0.0064) were observed during treatment. Despite tendential improvement, serum biliruhin, levels (18.2 +/- 9.4 vs. 16.9 +/- 9.4 mumol/l, p = 0.287) did not change significantly during treatment. Ursodeoxycholic acid may be beneficial in altering the natural course of chronic active hepatitis and of value in preventing mild attacks of immune hepatitis. The simple fact that ursodeoxycholic acid administration is essentially free of side-effects can go a long way towards justifying further clinically controlled studies.","PeriodicalId":17969,"journal":{"name":"Leber, Magen, Darm","volume":"26 6","pages":"310-3"},"PeriodicalIF":0.0,"publicationDate":"1996-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20034573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Helicobacter pylori eradication: finally clarity]. 【幽门螺杆菌根除:最终清晰】。

Leber, Magen, Darm Pub Date : 1996-11-01

J Labenz

引用次数: 0

[Aortoduodenal fistula as the cause of gastrointestinal hemorrhage]. 【十二指肠主动脉瘘管作为胃肠道出血的原因】。

Leber, Magen, Darm Pub Date : 1996-11-01

H E Adamek, M Maier, B Kohler, E L Zurmeyer, J F Riemann

引用次数: 0

[Cost savings with preoperative ambulatory diagnosis in elective gastrointestinal operations]. 择期胃肠手术术前门诊诊断的成本节约

Leber, Magen, Darm Pub Date : 1996-11-01

H Eisold

引用次数: 0

[Diagnosis and therapy of portal hypertension]. 【门脉高压的诊断与治疗】。

Leber, Magen, Darm Pub Date : 1996-11-01

B Frank, W G Zoller

{"title":"[Diagnosis and therapy of portal hypertension].","authors":"B Frank, W G Zoller","doi":"","DOIUrl":"","url":null,"abstract":"Portal hypertension, defined by a constant increase of the portal vein pressure over 5 to 10 mmHg, is usually caused by a pre-, intra- or posthepatic obstruction of the portal blood flow. Advances in ultrasound techniques like duplex or colour doppler enabled portal hypertension to be diagnosed safely in a noninvasive way. Invasive procedures for the measurement of portal pressure or blood flow are just applied for scientific and pharmacological questions. The therapy of portal hypertension concentrates on the treatment of its complications: The management of the acute variceal hemorrhage should follow a sequential regime. The treatment of the individual patient however, depends on the special experiences of the responsible doctor. In the primary and secondary prophylaxis of hemorrhage from esophageal varices the administration of portal pressure reducing agents like beta-blockers, sclerotherapy or banding of esophageal varices, represent effective strategies. Trials in the future should concentrate on the characterization of these patients, who show the best response to different prophylactic strategies. The treatment of ascites is according to a sequential procedure. Peritoneovenous shunts are usually not necessary. The transhepatic intrajugular portosystemic stent shunt offers a new therapeutic option of complications of portal hypertension. First studies show encouraging results.","PeriodicalId":17969,"journal":{"name":"Leber, Magen, Darm","volume":"26 6","pages":"284-90, 293-7"},"PeriodicalIF":0.0,"publicationDate":"1996-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20034571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Pseudo-esophagitis in antacid abuse]. [滥用抗酸剂引起假性食管炎]。

Leber, Magen, Darm Pub Date : 1996-11-01

B Bokemeyer, U Vogt, R Stadler, S Wagner

引用次数: 0

[Complications of percutaneous endoscopic gastrostomy (PEG)]. [经皮内镜胃造口术(PEG)的并发症]。

Leber, Magen, Darm Pub Date : 1996-09-01

U Drochner, F Mehnert

引用次数: 0

[Good results with Helicobacter pylori eradication for treatment of non-ulcer dyspepsia]. 【根除幽门螺杆菌治疗非溃疡性消化不良疗效良好】。

Leber, Magen, Darm Pub Date : 1996-09-01

H Bock, A Mares