{"title":"Near-infrared autofluorescence imaging for colonic cancer detection","authors":"Xiaozhuo Shao, Wei Zheng, Zhiwei Huang","doi":"10.1117/12.852098","DOIUrl":"https://doi.org/10.1117/12.852098","url":null,"abstract":"We explore an NIR autofluorescence imaging technique for cancer diagnosis and detection. A set of tissue images including NIR white light images, autofluorescence (AF) images and fluorescence polarized images (FPI) (parallel-, and perpendicular- polarization) were acquired in tandem on human colonic tissues. The results show that NIR fluorescence intensity of normal tissue is significantly higher than that of cancer tissue. The perpendicular-polarization image yields the highest diagnostic accuracy 93% compared to other imaging modes. This work demonstrates that Fluorescence polarization imaging (FPI) technique has great potential for cancer diagnosis and detection in the colon.","PeriodicalId":179447,"journal":{"name":"SPIE/OSA/IEEE Asia Communications and Photonics","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124233808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metabolic mapping of cell culture growth by NADH fluorescence lifetime imaging","authors":"V. Ghukasyan, T. Buryakina, F. Kao","doi":"10.1117/12.855051","DOIUrl":"https://doi.org/10.1117/12.855051","url":null,"abstract":"Fluorescence lifetime imaging microscopy (FLIM) has been demonstrated as advantageous at discriminating between free and protein-bound forms of the NADH coenzyme, providing not only with the lifetimes of the both states (shorter τ1 and longer τ2), but also with the relative concentrations of both (fractions a1 and a2 correspondingly). Given the role of NADH in cellular energetics, NADH FLIM has been applied for the noninvasive characterization of metabolic changes in a range of pathologies. However, for the discrimination of pathological states, a proper characterization of NADH fluorescence lifetime dynamics at physiological conditions has to be conducted. We have applied FLIM NADH for the characterization of metabolic changes during cell culture growth. Our results demonstrate that during the exponential growth stage there's a well expressed trends of gradual decrease of the free/bound ratio, as measured from the center from the cell colonies. At the same time the cells at the edges of a colony exhibit higher values of the ratio. Several possible reasons for the phenomena observed are discussed.","PeriodicalId":179447,"journal":{"name":"SPIE/OSA/IEEE Asia Communications and Photonics","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127495975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shaoling He, Xinyong Dong, K. Ni, C. Chan, P. Shum
{"title":"Temperature-insensitive 2-D fiber Bragg grating inclinometer","authors":"Shaoling He, Xinyong Dong, K. Ni, C. Chan, P. Shum","doi":"10.1117/12.851271","DOIUrl":"https://doi.org/10.1117/12.851271","url":null,"abstract":"A two-dimensional (2-D) inclinometer based on three optical fiber Bragg gratings (FBGs) is proposed and demonstrated. Preliminary experiments show that a high measurement sensitivity of 192 pm/° and resolution of 0.005° can be achieved and this sensor is proved to be insensitive to temperature.","PeriodicalId":179447,"journal":{"name":"SPIE/OSA/IEEE Asia Communications and Photonics","volume":"327 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133155992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Design of athermal all-polymer waveguide microring resonator","authors":"X. Han, Mingshan Zhao, Jianing Zhang, Linghua Wang, J. Teng, Jinyan Wang, X. Jian","doi":"10.1117/12.850677","DOIUrl":"https://doi.org/10.1117/12.850677","url":null,"abstract":"The athermal all-polymer waveguide microring resonator is realized by selecting polymer substrate with proper thermal expansion coefficient to substitute the silicon one. The designed results show that the maximal resonant wavelength shift is -0.0085nm and the maximal temperature dependent wavelength shift slope is -0.0009nm/K when the temperature varies from 20°C to 65°C.","PeriodicalId":179447,"journal":{"name":"SPIE/OSA/IEEE Asia Communications and Photonics","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127562333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study on high-speed photodetectors with plasmonics flilter","authors":"Yufeng Shang, Yongqing Huang, X. Duan, X. Ye, Hui Huang, Shiwei Cai, Qi Wang, X. Ren","doi":"10.1117/12.851962","DOIUrl":"https://doi.org/10.1117/12.851962","url":null,"abstract":"A new photodetector was designed with Metal Aperture Arrays filter in this paper. The shape and dimensions of the holes in an arrays do influence its transmission spectrum compare to the conventional photodetector. Hole array and annular aperture arrays were discussed.","PeriodicalId":179447,"journal":{"name":"SPIE/OSA/IEEE Asia Communications and Photonics","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114128023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reliability-guaranteed path protection under multiple constraints","authors":"Yang Liu, Zheng Zheng, Xingchun Liu","doi":"10.1117/12.852163","DOIUrl":"https://doi.org/10.1117/12.852163","url":null,"abstract":"The path protection with reliability guarantee is investigated under multiple constraints. The key challenge of providing ample multi-constrained loop-less paths to the detouring as candidates is addressed by a modified relaxation principle of dominated path. The loops in the new extended sub-paths are explored with an elastic depth, and additive criterions derived from the path information are adopted to obtain more accurate identification of feasible paths. Our hybrid detouring gives priority to the end to end disjoint backup paths and uses the residual space of inter-media nodes to store the potential local disjoint subpaths. The obtained candidate backup paths are selected by appropriate cost functions according to the combined reliability and the consumed resources. Simulation results demonstrate its superiority in restoration path-finding capability leads to a significant improvement in the success rate of the QoS path protection.","PeriodicalId":179447,"journal":{"name":"SPIE/OSA/IEEE Asia Communications and Photonics","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128313820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Principle, technology, and challenge of radio over fiber (RoF) based broadband access for metro and intercity trains","authors":"Michael M. Zhou","doi":"10.1117/12.852158","DOIUrl":"https://doi.org/10.1117/12.852158","url":null,"abstract":"In this article the author presents the RoF technology based broadband access network architecture for the metro and intercity trains, analyzes the relating issues in realizing the network, and addresses challenges towards the direction. The author first identifies insufficiency of the present wireless communication infrastructure, reviews the RoF technology and its characteristics, presents the network architecture meeting the performance and reliability, describes multi-diversities mechanisms for the two-channel transmission, discusses the RoF system structures and their realization, and finally analyzes the issues of the MMW propagation.","PeriodicalId":179447,"journal":{"name":"SPIE/OSA/IEEE Asia Communications and Photonics","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122043888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reconfigurable multiport EPON repeater","authors":"M. Oishi, R. Inohara, A. Agata, Y. Horiuchi","doi":"10.1117/12.852144","DOIUrl":"https://doi.org/10.1117/12.852144","url":null,"abstract":"An extended reach EPON repeater is one of the solutions to effectively expand FTTH service areas. In this paper, we propose a reconfigurable multi-port EPON repeater for effective accommodation of multiple ODNs with a single OLT line card. The proposed repeater, which has multi-ports in both OLT and ODN sides, consists of TRs, BTRs with the CDR function and a reconfigurable electrical matrix switch, can accommodate multiple ODNs to a single OLT line card by controlling the connection of the matrix switch. Although conventional EPON repeaters require full OLT line cards to accommodate subscribers from the initial installation stage, the proposed repeater can dramatically reduce the number of required line cards especially when the number of subscribers is less than a half of the maximum registerable users per OLT. Numerical calculation results show that the extended reach EPON system with the proposed EPON repeater can save 17.5% of the initial installation cost compared with a conventional repeater, and can be less expensive than conventional systems up to the maximum subscribers especially when the percentage of ODNs in lightly-populated areas is higher.","PeriodicalId":179447,"journal":{"name":"SPIE/OSA/IEEE Asia Communications and Photonics","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129726184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Weilin Xie, Yi Dong, Qingyuan Lin, Yaohui Jin, Weisheng Hu, H. Huang, Jianming Wu
{"title":"Limit beat-frequency noise by employing receive low-pass filter and earn extra power budget margin for dual-band RSOA-based WDM-PON","authors":"Weilin Xie, Yi Dong, Qingyuan Lin, Yaohui Jin, Weisheng Hu, H. Huang, Jianming Wu","doi":"10.1117/12.804347","DOIUrl":"https://doi.org/10.1117/12.804347","url":null,"abstract":"In this work, we use a low-pass filter in the burst-mode receiver between PIN+TIA and LA to optimize the receive bandwidth, and finally to improve the receiver performance of uncooled Reflective-SOA-based WDM-PON significantly. In addition, an extra power budget is earned for further development.","PeriodicalId":179447,"journal":{"name":"SPIE/OSA/IEEE Asia Communications and Photonics","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115039910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"p-cycle-based strategy for adaptive PWCE design","authors":"Zhenrong Zhang, Zhengbin Li, Yongqi He, A. Xu","doi":"10.1117/12.804226","DOIUrl":"https://doi.org/10.1117/12.804226","url":null,"abstract":"Future WDM optical networks are foreseen to be more dynamic and sensitive to failures. Therefore, dynamic service provisioning with network survivability becomes a critical requirement for network planning and management. The concept of protected working capacity envelope (PWCE) is attractive because it does not need protection resources to be dynamically configured thereby simplifying network management and reducing processing overheads. In this paper, we consider a p-Cycle-based Strategy for adaptive PWCE (protected working capacity envelope) design where PWCE can adaptively change with dynamically changing traffic. The blocking performance of this new strategy is compared to that of p-Cycle-based PWCE under a dynamic and non-uniform traffic model. The results show that the new strategy can adapt well to dynamic traffic demands that are non-uniform among the network nodes.","PeriodicalId":179447,"journal":{"name":"SPIE/OSA/IEEE Asia Communications and Photonics","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126565406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}