Korean Journal of Family Medicine最新文献

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Elderly Abuse and Neglect on Population Health: Literature Review and Interventions from Selected Countries. 老年人虐待和忽视对人口健康的影响:文献综述和特定国家的干预措施。
IF 2.3
Korean Journal of Family Medicine Pub Date : 2023-11-01 Epub Date: 2023-08-29 DOI: 10.4082/kjfm.23.0046
Ahmad Nabeil Alias, Khalid Mokti, Mohd Yusof Ibrahim, Sahipudin Saupin, Mohd Faizal Madrim
{"title":"Elderly Abuse and Neglect on Population Health: Literature Review and Interventions from Selected Countries.","authors":"Ahmad Nabeil Alias, Khalid Mokti, Mohd Yusof Ibrahim, Sahipudin Saupin, Mohd Faizal Madrim","doi":"10.4082/kjfm.23.0046","DOIUrl":"10.4082/kjfm.23.0046","url":null,"abstract":"<p><p>Elderly abuse and neglect are among the primary public health problems linked to global demographic changes in the population, impacting not only the well-being of the elderly but also the growth of the nation or economy. This article discusses the effects of elder abuse and neglect on population health from the national and international perspectives through a narrative review of previously published articles on the concept of aging, the prevalence of elderly abuse and neglect, its risk factors and effects, and finally measures, legal perspectives, and recommendations to curb it. Interventions in Malaysia and selected nations, including Indonesia, South Korea, the United States, Australia, and Hong Kong, are examined. This issue is important as the majority of countries are moving toward being elderly populations. Improving global surveillance and the monitoring of instances is essential to inform policy actions to prevent elder abuse. In addition, a thorough assessment of the identified risk factors for violence and steps to prevent violence is required.</p>","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":" ","pages":"311-318"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10484384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous Iron Therapy: Re-administration after Prior Adverse Reaction. 静脉铁治疗:既往不良反应后再次给药。
IF 2.3
Korean Journal of Family Medicine Pub Date : 2023-11-01 Epub Date: 2023-08-18 DOI: 10.4082/kjfm.23.0039
Tim Aung, Hla Thein, Sandy Tin Aung, Benjamin Tin Aung Soe, Ei Ohnmar
{"title":"Intravenous Iron Therapy: Re-administration after Prior Adverse Reaction.","authors":"Tim Aung, Hla Thein, Sandy Tin Aung, Benjamin Tin Aung Soe, Ei Ohnmar","doi":"10.4082/kjfm.23.0039","DOIUrl":"10.4082/kjfm.23.0039","url":null,"abstract":"<p><strong>Background: </strong>Intravenous (IV) iron therapy is performed in community practices and hospitals with modern formulations when oral administration becomes impractical. Effective replacement of iron is important for the treatment of iron deficiency and anemia. Can IV iron be rechallenged in individuals with a history of adverse reactions? This review is to explore the challenge of this, when clinically indicated.</p><p><strong>Methods: </strong>After performing a literature search, five studies (combined total sample number=1,006) for re-exposure of IV iron to individuals with a history of past reactions were identified, observed, and analyzed. Re-exposure included reactions ranging from mild to moderate and few cases of severe type.</p><p><strong>Results: </strong>The majority (>80%) of IV iron rechallenges were tolerable, safe, and successful without major serious incidents. There were no reports of major reactions (severe hypersensitivity reactions or anaphylaxis) in these re-exposures.</p><p><strong>Conclusion: </strong>Re-administration of IV iron therapy in patients with a previous adverse reaction is plausible, with benefit and risk stratification. A rechallenge would depend on the nature and degree of the adverse reaction and use of alternative formulations. Rechallenge to a previous severe hypersensitivity reaction or anaphylaxis with the same product has not been reported in these studies. Evidence on the benefit of premedication use is conflicting and requires further studies.</p>","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":" ","pages":"350-354"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10034080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender Difference of the Association between Energy Intake Expenditure Balance and Depression among Korean Adults: A Cross-Sectional Study from the 2014, 2016, and 2018 Korea National Health and Nutrition Examination Survey. 韩国成年人能量摄入、消耗平衡与抑郁之间关系的性别差异:来自2014年、2016年和2018年韩国国家健康与营养调查的横断面研究
IF 2.3
Korean Journal of Family Medicine Pub Date : 2023-11-01 Epub Date: 2023-08-31 DOI: 10.4082/kjfm.22.0165
Eunho Lee, Ha Jin Kim, Jusam Hwang, Minseon Park
{"title":"Gender Difference of the Association between Energy Intake Expenditure Balance and Depression among Korean Adults: A Cross-Sectional Study from the 2014, 2016, and 2018 Korea National Health and Nutrition Examination Survey.","authors":"Eunho Lee, Ha Jin Kim, Jusam Hwang, Minseon Park","doi":"10.4082/kjfm.22.0165","DOIUrl":"10.4082/kjfm.22.0165","url":null,"abstract":"<p><strong>Background: </strong>Diet and physical activity are key factors related to depressive mood. Previous studies have demonstrated the effects of diet and physical activity on depression. However, the effect of energy intake-expenditure balance (EIEB) on mental health has not been fully evaluated. This study aimed to analyze the association between EIEB and depression.</p><p><strong>Methods: </strong>A total of 13,460 participants (5,660 men and 7,800 women) aged ≥19 years were obtained from the 2014, 2016, and 2018 Korea National Health and Nutrition Examination Survey (KNHANES). EIEB was defined as the difference between the daily energy intake and energy expenditure. Energy intake was calculated and provided by the KNHANES using a 24-hour recall survey. Energy expenditure was estimated as the sum of basal metabolic rate and physical activity. Logistic regression analyses were used to investigate the association between sex-specific quartile groups (Q1-Q4) of EIEB and depression after adjusting for socioeconomic status, body mass index, lifestyle factors, and underlying diseases.</p><p><strong>Results: </strong>Women in Q3 of EIEB (211-669 kcal) had a significantly lower risk of depression (odd ratio [OR], 0.78; 95% confidence interval [CI], 0.67-0.92) than those in Q1 of EIEB (<-167 kcal). The adjusted ORs of depression were 0.87 (95% CI, 0.75-1.02) in Q2 and 0.86 (95% CI, 0.74-1.01) in Q4, with P for trend=0.030. There were no significant associations between the EIEB quartile groups and depression in men after adjusting for potential confounders (P for trend=0.564).</p><p><strong>Conclusion: </strong>Our results suggested that the EIEB is negatively associated with depression in Korean women.</p>","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":" ","pages":"319-326"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10176953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Content Analysis of YouTube Videos on the Effect of Vitamin C on Common Cold. 关于维生素C对普通感冒影响的YouTube视频内容分析。
IF 2.3
Korean Journal of Family Medicine Pub Date : 2023-11-01 Epub Date: 2023-10-18 DOI: 10.4082/kjfm.23.0093
Donghwi Park, Sang Gyu Kwak, Saeyoon Kim, Min Cheol Chang
{"title":"Content Analysis of YouTube Videos on the Effect of Vitamin C on Common Cold.","authors":"Donghwi Park, Sang Gyu Kwak, Saeyoon Kim, Min Cheol Chang","doi":"10.4082/kjfm.23.0093","DOIUrl":"10.4082/kjfm.23.0093","url":null,"abstract":"<p><strong>Background: </strong>With the growth of the Internet, social media platforms have emerged as major sources of medical information. We assessed the reliability, quality, and accuracy of the most-viewed YouTube videos containing information on the effect of vitamin C on the common cold.</p><p><strong>Methods: </strong>The YouTube videos were searched on August 1, 2022, using the keywords: (\"ascorbic acid\" OR \"vitamin C\" OR \"Sodium Ascorbate\" OR \"L-ascorbic\") AND \"common cold\". The 30 most-viewed videos were included in our study. The reliability and quality of the videos were analyzed using modified DISCERN and Global Quality Scales, respectively. When the videos included at least one correct or inaccurate scientific statement about the effect of vitamin C on the common cold, they were classified as accurate or misleading videos, respectively; those without any pertinent information were considered neither accurate nor misleading. If a video contained both accurate and inaccurate statements, it was classified as misleading.</p><p><strong>Results: </strong>Of the 30 most-viewed videos, 73% were unreliable, and 67% contained misleading information and were of a poor quality. Of these 30 videos, 14 videos were produced and posted by customers who were not specialized in medicine or nutrition. Moreover, these videos were of significantly lower reliability, quality, and accuracy than those produced by nutrition or fitness channels or by medical or nutrition professionals.</p><p><strong>Conclusion: </strong>The reliability, quality, and accuracy of videos uploaded by non-professionals were low. Therefore, video creators should upload reliable, high-quality videos to ensure the dissemination of accurate medical information.</p>","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":" ","pages":"342-346"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41236549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Examining the Association between Cigarette Smoking Quantity and Subjective Salt Taste Preference and Salt-Related Eating Behavior. 研究吸烟量与主观盐口味偏好和盐相关饮食行为之间的关系。
IF 2.3
Korean Journal of Family Medicine Pub Date : 2023-11-01 Epub Date: 2023-08-30 DOI: 10.4082/kjfm.23.0027
Jian Ma, Yeon-Kyung Lee
{"title":"Examining the Association between Cigarette Smoking Quantity and Subjective Salt Taste Preference and Salt-Related Eating Behavior.","authors":"Jian Ma, Yeon-Kyung Lee","doi":"10.4082/kjfm.23.0027","DOIUrl":"10.4082/kjfm.23.0027","url":null,"abstract":"<p><strong>Background: </strong>Smoking can reduce taste sensitivity, the ability to sense various tastes, and diet quality and can increase the incidence of diseases such as hypertension. This study aimed to analyze the association between the smoking amount, subjective salt preference, and salt-related eating behaviors.</p><p><strong>Methods: </strong>Data of more than 16 million individuals from the Korean Community Health Survey were used. Forest plots were drawn to compare the cumulative odds ratios of salt taste preference and salt-related eating behaviors, adjusted for sex, age, body mass index, education level, household income, marital status, and drinking status at various smoking levels.</p><p><strong>Results: </strong>Subjective salt preference and salt-related eating behaviors increased with smoking amount; the adjusted odds ratios (AORs) for smoking >20 cigarettes were higher than those for smoking <20 cigarettes. For daily smokers, the AOR was 1.27 (95% confidence interval [CI], 1.22-1.31) for 1-5 cigarettes per day and 1.68 (95% CI, 1.65-1.71) for 16-20 cigarettes per day (P<0.001). Smokers were more likely to have more frequent salt-related eating behaviors than nonsmokers.</p><p><strong>Conclusion: </strong>The subjective salt preference of smokers was higher than that of nonsmokers. Additionally, smokers used salt or soy sauce and dipped fried food in soy sauce more frequently than nonsmokers, which was also related to smoking amount.</p>","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":" ","pages":"335-341"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10120773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tobacco Use among School-Age Adolescents in Indonesia: Findings from the 2015 Indonesia Global School-Based Student Health Survey. 印度尼西亚学龄青少年烟草使用情况:2015年印度尼西亚全球校本学生健康调查结果
IF 2.3
Korean Journal of Family Medicine Pub Date : 2023-11-01 Epub Date: 2023-08-31 DOI: 10.4082/kjfm.23.0010
Zulfikar Ihyauddin, Dwi Astuti Dharma Putri, Jeslyn Tengkawan, Fitriana Murriya Ekawati, Mei Neni Sitaresmi
{"title":"Tobacco Use among School-Age Adolescents in Indonesia: Findings from the 2015 Indonesia Global School-Based Student Health Survey.","authors":"Zulfikar Ihyauddin, Dwi Astuti Dharma Putri, Jeslyn Tengkawan, Fitriana Murriya Ekawati, Mei Neni Sitaresmi","doi":"10.4082/kjfm.23.0010","DOIUrl":"10.4082/kjfm.23.0010","url":null,"abstract":"<p><strong>Background: </strong>Although Indonesia has a considerable proportion of adolescent smokers, nationally representative studies of its determinants remain limited. The 2015 Indonesian Global School-Based Student Health Survey (GSHS) was conducted with school-age adolescents and provided information about smoking behavior. This study aimed to examine the prevalence, determinants, and correlates of tobacco use among adolescents in Indonesia using the GSHS survey.</p><p><strong>Methods: </strong>A secondary data analysis of a cross-sectional study was conducted using data from the 2015 Indonesian GSHS. Multivariate logistic regression was used to assess the determinants and correlates of tobacco use.</p><p><strong>Results: </strong>Our analysis showed that 9.1% of school-age adolescents had used tobacco products in the past 30 days. Most were 13-15 years (61.7%) and had attempted to stop smoking (92.4%). After adjusting for covariates, significant risk factors associated with tobacco smoking were older age groups (prevalence odds ratio [POR], 3.01-9.40; 95% confidence interval [CI], 1.71-23.1), male (POR, 13.7; 95% CI, 8.71-21.5), psychological distress (POR, 1.41; 95% CI, 1.05-1.90), smoking exposure (POR, 1.98-2.15; 95% CI, 1.35-3.42), and when both parents smoked (POR, 2.96; 95% CI, 1.78-4.94). In addition, tobacco use was associated with other risky behaviors, including sex with multiple partners, using drugs, drinking alcohol, and being involved in physical fights.</p><p><strong>Conclusion: </strong>Tobacco use is high among Indonesian adolescents. This prevalence highlights the need for a more stringent tobacco control policy and tailored cessation programs for adolescents by considering important modifiable determinants of tobacco use among adolescents, including risky smoking-related behaviors.</p>","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":" ","pages":"327-334"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10176957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Macroamylasemia as a Rare Cause of Hyperamylasemia: A Case Report. 大淀粉酶血症是高淀粉酶血症的罕见病因:1例报告。
IF 2.3
Korean Journal of Family Medicine Pub Date : 2023-11-01 Epub Date: 2023-11-17 DOI: 10.4082/kjfm.23.0195
Wejdan M Al-Johani
{"title":"Macroamylasemia as a Rare Cause of Hyperamylasemia: A Case Report.","authors":"Wejdan M Al-Johani","doi":"10.4082/kjfm.23.0195","DOIUrl":"10.4082/kjfm.23.0195","url":null,"abstract":"<p><p>Macroamylasemia is a rare condition characterized by the formation of an amylase-globulin complex that is too large to be readily excreted by the kidneys and leads to elevated serum amylase levels. It is a benign condition lacking severe signs and symptoms that does not require treatment. This paper presents a case of a middle-aged man with unexplained elevated serum amylase levels. Despite an initially elevated triglyceride level, clinical findings, laboratory test results, and radiological findings were not suggestive of pancreatitis. The ratio of renal amylase clearance to creatinine clearance was calculated at <1%, consistent with macroamylasemia. No specific treatment was given, and he was monitored periodically. Nevertheless, macroamylasemia is a diagnostic challenge because of the need to differentiate it from other causes of hyperamylasemia to avoid unnecessary tests and treatments.</p>","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":"44 6","pages":"347-349"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138291333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
YouTube, Health Information, and Health Literacy. YouTube,健康信息和健康素养。
IF 2.3
Korean Journal of Family Medicine Pub Date : 2023-11-01 Epub Date: 2023-11-17 DOI: 10.4082/kjfm.44.6E
Seung-Won Oh
{"title":"YouTube, Health Information, and Health Literacy.","authors":"Seung-Won Oh","doi":"10.4082/kjfm.44.6E","DOIUrl":"10.4082/kjfm.44.6E","url":null,"abstract":"","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":"44 6","pages":"301-302"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138291334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Family Involvement to Stop the Conversion of Prediabetes to Diabetes. 家庭参与阻止糖尿病前期转化为糖尿病。
IF 2.3
Korean Journal of Family Medicine Pub Date : 2023-11-01 Epub Date: 2023-08-14 DOI: 10.4082/kjfm.23.0019
Denny Anggoro Prakoso, Yodi Mahendradhata, Wahyudi Istiono
{"title":"Family Involvement to Stop the Conversion of Prediabetes to Diabetes.","authors":"Denny Anggoro Prakoso, Yodi Mahendradhata, Wahyudi Istiono","doi":"10.4082/kjfm.23.0019","DOIUrl":"10.4082/kjfm.23.0019","url":null,"abstract":"<p><p>Prediabetes is a condition associated with an increased risk of developing diabetes, in which blood glucose levels are high but not high enough to be diagnosed as diabetes. The rapid increase in the prevalence of prediabetes is a major global health challenge. The incidence of prediabetes has increased to pandemic levels and can lead to serious consequences. Unfortunately, nearly 90% of prediabetic individuals are unaware of their ailment. A quarter of prediabetic individuals develop type 2 diabetes mellitus (T2DM) within 3-5 years. Although prediabetes is a reversible condition, the prevention of diabetes has received little attention. It is essential for prediabetic individuals to implement new health-improvement techniques. Focusing on family systems is one strategy to promote health, which is determined by health patterns that are often taught, established, and adjusted within family contexts. For disease prevention, a family-based approach may be beneficial. Family support is essential for the metabolic control of the disease. This study aimed to show several strategies for involving the patient's family members in preventing the conversion of prediabetes to T2DM and to emphasize that the patient's family members are a valuable resource to reduce the incidence of diabetes.</p>","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":" ","pages":"303-310"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10359405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low Serum Creatinine as Well as High Serum Creatinine Is Associated with Prognosis of Patients with Cancer in End-of-Life. 低血清肌酸和高血清肌酸与癌症患者的预后相关。
IF 2.3
Korean Journal of Family Medicine Pub Date : 2023-10-27 DOI: 10.4082/kjfm.23.0116
Yoo Jeong Lee, Soon-Young Hwang, Su Hyun Kim, Youn Seon Choi
{"title":"Low Serum Creatinine as Well as High Serum Creatinine Is Associated with Prognosis of Patients with Cancer in End-of-Life.","authors":"Yoo Jeong Lee,&nbsp;Soon-Young Hwang,&nbsp;Su Hyun Kim,&nbsp;Youn Seon Choi","doi":"10.4082/kjfm.23.0116","DOIUrl":"https://doi.org/10.4082/kjfm.23.0116","url":null,"abstract":"<p><strong>Background: </strong>The prognosis of end-of-life patients is challenging, and clinicians have attempted to predict survival more accurately. High serum creatinine (sCr) levels are associated with lower survival rates in patients with various cancers; however, low sCr levels are commonly expected in patients with terminal cancer because of muscle wasting and malnutrition. Therefore, we investigated the prevalence of low and high sCr levels and their association with survival duration in patients with terminal cancer in a palliative care unit.</p><p><strong>Methods: </strong>We analyzed the medical records of 280 patients admitted to a palliative care unit. Patients were divided into low (<0.5 mg/dL), normal (0.5-1.2 mg/dL), and high (>1.2 mg/dL) sCr groups. Kaplan-Meier survival curves using sCr levels were plotted and compared using the log-rank test. Using stepwise selection, a multivariable Cox proportional hazards model was used to identify the significant prognostic factors.</p><p><strong>Results: </strong>The median survival durations in the high-, low-, and normal-sCr groups were 9.57 days, 22.26 days, and 27.51 days, respectively. Multivariable Cox proportional hazard model identified that males (hazard ratio [HR], 1.81; 95% confidence interval [CI], 1.16-2.85), poor performance status (HR, 3.43; 95% CI, 1.12-10.54), total parenteral nutrition use (HR, 1.84; 95% CI, 1.09-3.1), high sCr (HR, 2.74; 95% CI, 1.52-4.94), and low sCr (HR, 1.22; 95% CI, 1.07-1.43) were significantly associated with a shorter survival time.</p><p><strong>Conclusion: </strong>Low and high serum creatinine levels were significantly associated with poor survival in patients with cancer at the end-of-life stage. Therefore, readily available and simple biomarkers may help plan advanced care in palliative care settings.</p>","PeriodicalId":17893,"journal":{"name":"Korean Journal of Family Medicine","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54229835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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