Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology最新文献

{"title":"Phantom Limb Pain Treated with Duloxetine: A case series","authors":"M. Dalkıran, A. Genc, B. Dikmen, İlknur Yıldırım, Ş. Turan","doi":"10.5455/BCP.20160411071457","DOIUrl":"https://doi.org/10.5455/BCP.20160411071457","url":null,"abstract":"Phantom limb pain (PLP) is a general complaint after amputation which is usually described as burning, tingling, shooting, and cramping. Spontaneous recovery of phantom limb pain generally last many months or years. The pain gets chronic in most cases and impresses the life quality of the patient. Here we present four cases of PLP, treated with duloxetine.","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74498025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risperidone and Lithium for Pathological Laughing","authors":"M. Şahpolat, A. Demir","doi":"10.1080/10177833.2016.11827160","DOIUrl":"https://doi.org/10.1080/10177833.2016.11827160","url":null,"abstract":"","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83245877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Intrauterine Antipsychotic Drug Exposure on Learning and Memory in Adult Rats","authors":"Çağatay Oltulu, Ç. Karadağ","doi":"10.5455/BCP.20160627090254","DOIUrl":"https://doi.org/10.5455/BCP.20160627090254","url":null,"abstract":"ABSTRACTObjective: The effects of antipsychotic drugs, of whose different classes can be used in the treatment of patients with resistant to schizophrenia, on the fetus and the benefits of the treatment to the mother should be taken into consideration before making a decision about initiating treatment. This study aimed to examine the effects of prenatal exposure to various antipsychotic agents on learning and memory in adult rats.Method: In this study, antipsychotic drugs from different chemical classes (2 mg/kg haloperidol, 100 mg/kg thioridazine, 200 mg/kg sulpiride, 20 mg/kg chlorprothixene, 40 mg/kg clozapine, 10 mg/kg fluphenazine, 20 mg/kg chlorpromazine) and water for the control group were administered to pregnant Sprague-Dawley dams through gavage during the pregnancy period. In total, 16 groups were created and tested in the Morris water maze by dividing offspring of eight mother rats into male and female rat groups (n=10) on postpartum day 60. Learning was tested with hidden platform task and ...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75687446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on FDA's Breakthrough Therapy Designation of Intranasal Esketamine for the Treatment of Major Depressive Disorder with Imminent Risk of Suicide","authors":"Rejish K Thomas, M. Cetin, G. Baker, S. Dursun","doi":"10.5455/BCP.20161027122045","DOIUrl":"https://doi.org/10.5455/BCP.20161027122045","url":null,"abstract":"","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79265741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extensive Gray Matter Volume Reduction and Correlations with Neuropsychological Performance in Alcohol Use Disorder Patients","authors":"Serdar Nurmedov, O. Noyan, B. Metin, Sehadet Ekmen, Cumhur Avcil, S. Kose","doi":"10.5455/BCP.20160223123949","DOIUrl":"https://doi.org/10.5455/BCP.20160223123949","url":null,"abstract":"ABSTRACTObjective: Long term alcohol use results in varying degrees of deficits in cognitive functions. Although the neocortex, particularly the frontal lobe; limbic system and cerebellum are the brain regions most vulnerable to the toxic effects of alcohol, neural correlates of neuropsychological deficits have not been studied directly.Methods: This voxel based morphometric (VBM) study examined the effect of duration and amount of alcohol exposure on gray matter (GM) volume and the relation between GM volumes and neuropsychological deficits in patients with Alcohol Use Disorder (AUD).Results: Voxel-wise whole brain analysis showed extensive regional gray matter volume for AUD patients and GM volumes were inversely correlated to the amount of alcohol exposure. More importantly, there were statistically significant correlations between different indices of executive functioning and GM volumes.Conclusion: These results indicate that dose-dependent alcohol effect on prefrontostriatal and temporal circuitries...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80900491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finding the Right Balance Between Clinical Efficacy gHg and Side Effects in Second Generation Antipsychotics","authors":"O. Durmaz","doi":"10.5455/BCP.20150902042049","DOIUrl":"https://doi.org/10.5455/BCP.20150902042049","url":null,"abstract":"","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73801693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antioxidant Status and DNA Damage in Children with Attention Deficit Hyperactivity Disorder with or without Comorbid Disruptive Behavioral Disorders","authors":"Şeref Şimşek, Salih Gençoğlan, Soner Ozaner, İ. Kaplan, M. Kaya","doi":"10.5455/BCP.20151003063820","DOIUrl":"https://doi.org/10.5455/BCP.20151003063820","url":null,"abstract":"Objective: The aim of this study is to investigate oxidative stress and DNA damage among children with attention deficit hyperactivity disorder (ADHD) with or without disruptive behavioral disorder...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73895050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of restless legs syndrome among psychiatric patients who are under antidepressant or antipsychotic monotherapy","authors":"M. Semiz, V. Solmaz, D. Aksoy, S. Inanir, B. Çolak, M. Gokbakan, A. Inanir","doi":"10.5455/BCP.20150908024954","DOIUrl":"https://doi.org/10.5455/BCP.20150908024954","url":null,"abstract":"Objective: Several groups of medications, such as dopamine blockers, analgesics and antihistaminergics were associated with restless legs syndrome (RLS). Although case reports showed some significant relations, they have many methodological limitations such as co-medications or medical co-morbidities. The aim of this study was to investigate the prevalence and severity of RLS in patients on antidepressant (AD) or antipsychotic (AP) monotherapy. \u0000Methods: One hundred and ninety-seven patients and 150 healthy controls were included in the study. RLS was diagnosed according to the International Restless Legs Syndrome Study Group (IRLSSG) criteria. The severity of RLS was evaluated according to IRLSSG rating scale. Participants diagnosed with RLS went under further neurological and psychiatric investigation for excluding secondary causes. \u0000Results: One hundred and twenty patients (60.9%) were on AD therapy, while 77 patients (39.1%) were on AP monotherapy. Thirty-two patients (16.2%) and seven controls (4.7%) were diagnosed with RLS according to IRLSSG criteria. The most frequent cause of RLS was quetiapine (28.5%) in the antipsychotic group and paroxetine (22.2%) in the antidepressant group. There was no statistically significant correlation between drug usage duration and RLS severity. \u0000Conclusion: AD or AP induced RLS is a common condition. ADs and APs should be considered as a cause for RLS when assesing RLS in psychiatric patients who are under treatment either of these medications.","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74983946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The changes of the cognitive and psychomotor functions in the chronic cannabis users after a month of remission","authors":"G. Umut, M. Atagün, C. Evren, H. Cengel, Ozge Hisim, Cahit Keskinkiliç","doi":"10.5455/BCP.20151019014343","DOIUrl":"https://doi.org/10.5455/BCP.20151019014343","url":null,"abstract":"Objective: In our study, it is aimed to investigate impacts of cannabis use on information processing and psychomotor functions and to examine changes in the cognitive functions at the end of abstinence over a month. \u0000Method: The study was initiated with 34 volunteer participants using cannabis at least over two years, directed by a forensic unit. 34 persons were assessed at admission and were planned to assess after a month of remission. As 14 participants discontinued the study 20 participants only were assessed again at the end of a month. The participants were applied The Montreal Cognitive Assessment (MOCA) test, Edinburgh Handedness Inventory, Finger Tapping Test (FTT), Adult Memory and Information Processing Battery (AMIPB) A and B, and simple reaction time tests (auditory and visual) in admission and were applied Finger Tapping Test (FTT), Adult Memory and Information Processing Battery (AMIPB), and simple reaction time tests (auditory and visual) at the end of a month. \u0000Results: There was no statistically significant difference between participants continue to the treatment and those discontinue in terms of sociodemographic and clinical characteristics. The participants discontinue were using more daily cannabis dose. The auditory reaction time of the group continue to the treatment decreased statistically significantly after a month whereas there was no statistically significant difference in the visual reaction time. The scores of the AMIPB-A and AMIPB-B were detected statistically higher after a month compared to admission. The score of the dominant hand FTT after a month was detected statistically higher than that in admission whereas there was no statistically significant difference in the non-dominant hand score. \u0000Conclusion: Improvements in scores of AMIP-A, AMIP-B, FTT and auditory reaction time after one month of quitting cannabis suggest that cannabis use may impair cognitive functions such as information processing, reaction time and motor functions. We suggest that future studies to assess cognitive functions after either a shorter (i.e. 1 week) or a longer (i.e. 2 months) period of cannabis abstinence in larger samples may provide further useful data about the relationship between cannabis use and cognitive functions.","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78026572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"VALIDITY AND RELIABILITY OF AM SAD, a SHORT GERIATRIC DEPRESSION SCREENING TOOL, IN TURKISH ELDERLY PEOPLE","authors":"P. Soysal, A. Işık, Cansu Usarel, D. Kaya, H. Ellidokuz, G. Grossberg","doi":"10.5455/BCP.20150910032337","DOIUrl":"https://doi.org/10.5455/BCP.20150910032337","url":null,"abstract":"ABSTRACTObjective: Depression is a serious public health problem among the elderly and screening for depression in the elderly for primary care physicians is essential. The objective of this study was to evaluate the validity and reliability of the AM SAD (Appetite, Mood, Sleep, Activity, and thoughts of Death) and to compare the results with DSM-5 depression criteria in Turkish elderly people.Methods: This study was conducted in a geriatric division of a tertiary hospital in the west part of Turkey, Izmir. A total of 186 elderly outpatients were included in the study. Translation from the original English version was performed according to the standardized methods. Yesavage Geriatric Depression-15 Scale (YGDS), and the “AM SAD” were administered following by the Mini-Mental Status Examination (MMSE). Patients were assessed for depression using DSM-5 criteria and the results were compared with AM SAD.Results: A statistically significant correlation was established between YDGS-15 and AM SAD scores (r:0.64...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86559105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}