kimjunhyeong, Kang Mu Kwon, E. Lee, Daekeun Kim, Jeong-Sook Park, Jae hyeok Lee
{"title":"Antioxidant Activity of Beta vulgaris L. Methanol Extract in Caenorhabditis elegans","authors":"kimjunhyeong, Kang Mu Kwon, E. Lee, Daekeun Kim, Jeong-Sook Park, Jae hyeok Lee","doi":"10.22889/KJP.2020.51.3.192","DOIUrl":"https://doi.org/10.22889/KJP.2020.51.3.192","url":null,"abstract":" Caenorhabditis elegans model system was used to investigate the antioxidant activity of Beta vulgaris L. (Chenopodiaceae) methanol extract. The methanol extract showed DPPH radical scavenging and superoxide quenching activity in a dose-dependent manner. The B. vulgaris methanol extract was measured for the activity of superoxide dismutase (SOD), catalase, and oxidative stress tolerance by using C. elegans, along with reactive oxygen species (ROS) level. In addition, to see that the regulation of the stress response gene is responsible for the increased stress tolerance of C. elegans treated by the methanol extract, SOD-3 expression was measured using a transgenic strain. As a result, the B. vulgaris methanol extract increased SOD and catalase activities, and decreased ROS accumulation, dose-dependently. Furthermore, the methanol extract-treated CF1553 worm showed higher SOD-3::GFP intensity than the control.","PeriodicalId":17851,"journal":{"name":"Korean Journal of Pharmacognosy","volume":"131 1","pages":"192-198"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77824207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juree Kim, L. Paje, Jungwon Choi, Hak-Dong Lee, J. Shim, J. Shim, P. J. Geraldino, Sanghyun Lee
{"title":"Determination of Silymarin and Silybin Diastereomers in Korean Milk Thistle using HPLC/UV Analysis","authors":"Juree Kim, L. Paje, Jungwon Choi, Hak-Dong Lee, J. Shim, J. Shim, P. J. Geraldino, Sanghyun Lee","doi":"10.22889/KJP.2020.51.4.297","DOIUrl":"https://doi.org/10.22889/KJP.2020.51.4.297","url":null,"abstract":"","PeriodicalId":17851,"journal":{"name":"Korean Journal of Pharmacognosy","volume":"96 1","pages":"297-301"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82777142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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