Jurnal Penelitian Farmasi & Herbal最新文献_第3页

ANALISIS CEMARAN LOGAM BERAT TIMBAL (Pb) PADA MAKANAN DAN MINUMAN : STUDI LITERATUR

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-10-31 DOI: 10.36656/jpfh.v5i1.1038

Audi Ichsani Aribowo, Bunga Nur Annisa, Nena Vauziah Sary, Lina Nurfadhila, Marsah Rahmawati Utami

引用次数: 0

UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL RUMPUT MUTIARA (Hedyotis corymbosa L. Lamk) TERHADAP TIKUS PUTIH 测试白老鼠的抗炎症活性

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-10-31 DOI: 10.36656/jpfh.v5i1.858

Rani Ardiani

{"title":"UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL RUMPUT MUTIARA (Hedyotis corymbosa L. Lamk) TERHADAP TIKUS PUTIH","authors":"Rani Ardiani","doi":"10.36656/jpfh.v5i1.858","DOIUrl":"https://doi.org/10.36656/jpfh.v5i1.858","url":null,"abstract":"Inflamation is the body’s defense mechanism in response to tissue injury and interference by external factors. Pearl grass (Hedyotis Corymbosa L.Lamk) is one of Rubiaceae family. Pearl grass have efficacy in the treatment as anti-inflamatory, anti-diabetic, anti-bacteria, and antioxidant. Pearl grass contains flavonoids has pharmacological effects as a anti-inflamatory. The purpose of this study was to determine the anti-inflamatory effect of ethanolic extract of pearl grass (EERM) on white rats incuded by λ- carragenan.This research was conducted by experimental method which included pearl grass extraction, phytochemical screening, and anti-inflamatory activity test of ethanolic of pearl gras with paw edema method using digital plethysmometer. As experimental animals 15 rats were divided into 5 groups, each group were 3 rats. As an inductor λ-carragenan 1 % was administered intraplantar. Sodium carboxy methyl cellulose (Na-CMC) 0,5 % as negative control, 2,25 mg/kg bw diclofenac dose as positif control and ethanolic extract of pearl grass dose 100 mg/kg bw, dose 200 mg/kg bw, and dose of 400 mg/kg bw as a test material given orally. Observations were made for 6 hours. The test data were analyzed statistically using one way ANOVA and continuced with Tukey’s B.The results of phytochemical indicated that ethanolic extract of pearl grass contained alkaloids, flavanoid, saponins, tanin and glycosides. The dosage of ethanolic extract of pearl grass 100 mg/kg bw, dose 200 mg/kg bw, dose 400 mg/kg bw has the effect as anti-inflamatory. The effective dose of ethanol extract of pearl grass as an anti-inflamatory in white rats was 400 mg/kg bw.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89912413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

STUDI FARMAKOVIGILANS PADA OBAT HERBAL 药学对草药的研究

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-10-31 DOI: 10.36656/jpfh.v5i1.1067

Cantika Nurul Sa’adah

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PENYALAHGUNAAN AMFETAMIN DAN DAMPAK PENGGUNA TERHADAP KESEHATAN DAN SOSIAL : LITERATURE REVIEW 安非他命的滥用以及使用者对健康和社会的影响:文学评论

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-10-31 DOI: 10.36656/jpfh.v5i1.1060

Bunga Nur Annisa, Indah Laily Hilmi, S. Salman

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Uji Aktivitas Antibakteri Ekstrak Etanol Daun Rambutan (Nephelium lappaceum L) Pada Pertumbuhan Bakteri Staphylococcus aureus dan Escherichia coli 红毛丹叶乙醇(nep液lappaceum L)对葡萄球菌aurecus和Escherichia大肠杆菌生长的抗菌活性进行测试

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-10-31 DOI: 10.36656/jpfh.v5i1.936

Nina Irmayanti Harahap

引用次数: 0

FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN GEL HAND SANITIZER EKSTRAK ETANOL DAUN BAYAM MERAH (Amaranthus Tricolor L.) TERHADAP BAKTERI Staphylococcus aureus & Eschericia coli 配方和抗菌活性检测剂凝胶手SANITIZER提取物红色菠菜叶乙醇(Amaranthus Tricolor)。对抗菌根球菌和大肠杆菌

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-10-31 DOI: 10.36656/jpfh.v5i1.939

Zola Efa Harnis

{"title":"FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN GEL HAND SANITIZER EKSTRAK ETANOL DAUN BAYAM MERAH (Amaranthus Tricolor L.) TERHADAP BAKTERI Staphylococcus aureus & Eschericia coli","authors":"Zola Efa Harnis","doi":"10.36656/jpfh.v5i1.939","DOIUrl":"https://doi.org/10.36656/jpfh.v5i1.939","url":null,"abstract":"Red spinach has function as skin antiseptic. It has antibacterial activity because it contains compounds such as tannins, flavonoids, saponins, and steroids. The purpose of formulation and test of antibacterial activity of hand sanitizer gel preparation red spinach extract and evaluation of physical quality of hand sanitizer. Antibacterial activity test was measured by diffusion method using paper disk to measuring the diameter of the bacterial growth inhibition zone of Escherichia coli and Staphylococcus aureus. Concentration extract ethanol of leaf red spinach (and formula of hand sanitizer gel used (F1) blanco; (F2) 5%; (F3) 10%; (F4) 20% and (F5) control positive/detol. Evaluation of physical properties of hand sanitizer gel include of: homogeneity test, stability test and pH test. The results has found showed that antibacterial activity test of gel extract leaves red spinach (on Escherichia coli inhibited at without extract/blanco was 0 mm, concentration of 5% with diameter of inhibit was 14,99 mm, concentration of 10% with diameter of inhibit was 17,26 mm, concentration of 20% with diameter of inhibit was 18,26 mm and using control positive was 19.33. And then for bacteri Staphylococcus aures at concentration of without extract/blanco was 0 mm, 5% with diameter of inhibit was 15,5 mm, concentration of 10% with diameter of inhibit was 15,96 mm and concentration of 20% with diameter of inhibit was 17,43 mm and using control positive was 18.33 mm. So we can conclude that hand sanitizer gel of leaf red spinach have less inhibited growth against Escherichia coli and Staphylococcus aureus.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90944839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Uji UJI EFEKTIVITAS GEL EKSTRAK ETANOL 70% GETAH GAMBIR (Uncaria gambir. Roxb) dan BETADINE TERHADAP LUKA SAYAT PADA TIKUS PUTIH JANTAN (Rattus norvegicus) GALUR 测试乙醇提取物凝胶70%碱液(Uncaria GAMBIR)的有效性。Roxb)和BETADINE用于雄性白老鼠(Rattus norvegicus)的出口伤口

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-10-31 DOI: 10.36656/jpfh.v5i1.1078

S. Sulasmi

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UJI EFEK ANTIPIRETIK DAUN SENDUDUK (Melastoma malabathricum L.) PADA TIKUS PUTIH JANTAN (Rattus Norvegicus) 测试檀香叶子的抗树脂效果。雄性白老鼠(学名Rattus Norvegicus)

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-10-31 DOI: 10.36656/jpfh.v5i1.972

Evi Depiana Gultom, Herti Ayu N Zebua, Robiatun Rambe

{"title":"UJI EFEK ANTIPIRETIK DAUN SENDUDUK (Melastoma malabathricum L.) PADA TIKUS PUTIH JANTAN (Rattus Norvegicus)","authors":"Evi Depiana Gultom, Herti Ayu N Zebua, Robiatun Rambe","doi":"10.36656/jpfh.v5i1.972","DOIUrl":"https://doi.org/10.36656/jpfh.v5i1.972","url":null,"abstract":"The antipyretic effect of flavonoid in senduduk leaf (Melastoma malabathricum L.) is one of the traditional medicines that people used. The goal of this study is to determine the antipyretic effect of the extract of Senduduk leaf (Melastoma malabathricum L.) in male white mice and compare it to paracetamol. The design of this experimental study was a post-test only controlled group design. Twenty-five Wistar furrow mice, aged two months and weighing 200 grams, were utilized as animal models. The mice were divided into five groups, one of which was the negative control group (2 ml water), First dosage of Senduduk leaf extract (100 mg/200 g body weight mice), second dose of the extract (200 mg/200 g body weight mice), and third dose of the extract (300 mg/200 g body weight mice). Temperature measurements were taken before and after the DPT vaccination was administered to mice, and every 30 minutes post treatment until 150 minutes. The result after observing treatment at 30 minutes for dose I (37.930C), dose II (37.760C), and dose III (37.450C). The results at 150 minutes for dose I (37,470C), for dose II (37,150C), and for dose III (36.880C). The result of the research was to analyzed using the one way ANOVA test. The results of statistical observations using the one way ANOVA method showed the significant value was p < 0.05 (0.000). This indicates there are differences from each treatment in antipyretic testing. If continued with the Tukey test, a significant value of p> 0.05 (0.9480), the research concluded that there is no difference in terms of antipyretic testing at a dose of 300mg/KgBW compared to paracetamol. The research concluded is the EEDS at a dose of 300mg/KgBW has the best antipyretic properties compared to paracetamol.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76278677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ANALISIS KADAR ASAM ASETAT HASIL FERMENTASI ECO-ENZYME DARI KULIT JERUK BALI (Citrus maxima Merr.) DAN POTENSINYA SEBAGAI ANTIOKSIDAN DENGAN METODE ALKALIMETRI DAN DPPH 分析葡萄柚皮(Citrus Merr)发酵的醋酸水平。它的抗氧化剂作用是碱性和DPPH方法

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-10-31 DOI: 10.36656/jpfh.v5i1.1069

B. Sembiring

{"title":"ANALISIS KADAR ASAM ASETAT HASIL FERMENTASI ECO-ENZYME DARI KULIT JERUK BALI (Citrus maxima Merr.) DAN POTENSINYA SEBAGAI ANTIOKSIDAN DENGAN METODE ALKALIMETRI DAN DPPH","authors":"B. Sembiring","doi":"10.36656/jpfh.v5i1.1069","DOIUrl":"https://doi.org/10.36656/jpfh.v5i1.1069","url":null,"abstract":"The garbage problem is a very important problem because it has the potential to damage the balance of the environmental ecosystem. Many studies have been carried out on the content of active compounds in grapefruit peel, but there are differences in sampling locations, types of solvents for extraction, differences in treatment and testing. In the discovery of Eco-enzyme fermentation solution product, Dr. Rosukon Poompanvong to help local farmers to obtain better yields while being friendly to the environment. Eco-Enzyme is a popular fermented fruit peel organic waste which has been developed because it is very practical, economical, and environmentally friendly. Utilization of fruit peels into Eco-Enzyme is an evolution of science in the health sector. \u0000This study aims to determine the Eco-Enzyme fermentation process from pomelo peel and Eco-Enzyme acetic acid levels and their potential as antioxidants with experimental research using Eco-Enzyme sample solution with FeCl3 solution as a qualitative test indicator for Eco-Enzyme samples. Quantitative test using 1-2 drops of Eco-Enzyme sample solution 0,1 M NaOH standard solution and phenolphthalein indicator solution in alkalimetric titration and DPPH method with DPPH solution using UV-Vis spectrophotometer. \u0000From the results of qualitative research, the results of Eco-Enzyme fermentation are in the form of a light brown solution, have a brick red precipitate, and there is a brick red precipitate. The results of quantitative research on alkalimetric titration of Eco-Enzyme fermentation, there is an acetic acid level of 7.5% per one gram of pomelo peel, and the DPPH method on the fermented Eco-Enyme solution with an IC50 value of 9.418075752 ppm, which means it has very strong antioxidant potential. \u0000Eco-enzyme sample solution has acetic acid level of 7,5% per one gram of pomelo peel and has very strong antioxidant potential","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90892676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FORMULASI SEDIAAN SALEP ANTI FUNGI EKSTRAK ETANOL BAWANG PUTIH (Allium sativum) TERHADAP PERTUMBUHAN JAMUR (Tricophyton mentagrophytes) SECARA IN VITRO

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-10-31 DOI: 10.36656/jpfh.v5i1.990

Firdaus Fahdi, Herviani Sari

{"title":"FORMULASI SEDIAAN SALEP ANTI FUNGI EKSTRAK ETANOL BAWANG PUTIH (Allium sativum) TERHADAP PERTUMBUHAN JAMUR (Tricophyton mentagrophytes) SECARA IN VITRO","authors":"Firdaus Fahdi, Herviani Sari","doi":"10.36656/jpfh.v5i1.990","DOIUrl":"https://doi.org/10.36656/jpfh.v5i1.990","url":null,"abstract":"Garlic contains flavonoids, tannins, and saponins which act as antifungals. The purpose of this study was to formulate an ethanol extract of garlic (Allium sativum) ointment with various concentrations of 5%, 10%, 15% and to evaluate the ointment preparation with physical evaluation requirements. Testing the activity of the ointment preparation against the fungus Trichophyton mentagrophytes was carried out by the diffusion method. The results showed that garlic (Allium sativum) could be formulated as an antifungal ointment preparation and met the requirements of the ointment preparation evaluation test with the results of the organoleptic test of the white ointment base, the 5% formulation being pale yellow, the 10% formulation and 15% brownish yellow. The homogeneity test showed no lumps in the ointment preparation, the pH test was in accordance with the requirements, namely 4.5-6.5. The dispersion test was in accordance with the requirements, namely 5-7 cm, and the adhesive data test was in accordance with the requirements, which was more than 4 seconds. The results showed that garlic (Allium sativum) ethanol extract ointment could inhibit the fungus Trichophyton mentagrophytes where a concentration of 15% produced an inhibition zone of 10.4500 mm, and as a comparison, miconazole ointment produced an inhibition zone of 14.3833 mm.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83757760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Jurnal Penelitian Farmasi &amp; Herbal最新文献

Jurnal Penelitian Farmasi & Herbal最新文献