Jurnal Kedokteran Brawijaya最新文献_第7页

Evaluation of the Antifertility Effect and Toxicity of Areca nut as Oral Contraceptive: Study on Male Rats 槟榔果口服避孕药对雄性大鼠的抗生育作用及毒性评价

Jurnal Kedokteran Brawijaya Pub Date : 2022-04-11 DOI: 10.21776/ub.jkb.2022.032.01.3

A. Rahman, H. Dewi, Billi Brian Geniro, Easti Vishiara Amdely

{"title":"Evaluation of the Antifertility Effect and Toxicity of Areca nut as Oral Contraceptive: Study on Male Rats","authors":"A. Rahman, H. Dewi, Billi Brian Geniro, Easti Vishiara Amdely","doi":"10.21776/ub.jkb.2022.032.01.3","DOIUrl":"https://doi.org/10.21776/ub.jkb.2022.032.01.3","url":null,"abstract":"Currently, very few male contraceptive methods are available. Areca nuts are known to have an antifertility effect, but the effective, safe dose is not certainly known. Data on its effectiveness and safety are needed to develop the potential of the areca nuts as an herbal contraceptive in men. This study determines the antifertility effect of areca nut administration at doses of 40, 30, and 20 mg/kgBW and their safety on the kidneys and liver. The green-colored raw areca nuts were used. The treatment groups were male rats whose fertility status was known before treatment. The control group were given distilled water. The treatment were given one dose a daily dissolved for 28 days of treatment, then male rats were bred again. Rats were terminated for histopathological examination of liver, kidneys, testes, and for analysis of spermatozoa. The administration of areca nuts caused a decreasing number of litters, but only the group given 40 mg/kgBW dose had a significant decrease (p<0.05). There were a damaged testes, a decreasing number and motility of spermatozoa as well as increasing spermatozoa abnormalities. There were no changes in liver tissue, but there was a mild grade cast in kidney tissue. Areca nut have antifertility effect in male rats with dose dependent manner, histopathological examination revealed cast nephotoxic but not hepatotoxic.","PeriodicalId":17705,"journal":{"name":"Jurnal Kedokteran Brawijaya","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73519654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Theory of Planned Behavior to Identify Out-of-Hospital Cardiac Arrest (OHCA) Bystanders' Intentions 院外心脏骤停旁观者意图的计划行为理论研究

Jurnal Kedokteran Brawijaya Pub Date : 2022-04-11 DOI: 10.21776/ub.jkb.2022.032.01.11

Zenita Habibatul Ilmiyah, S. Andarini, Tony Suharsono

{"title":"The Theory of Planned Behavior to Identify Out-of-Hospital Cardiac Arrest (OHCA) Bystanders' Intentions","authors":"Zenita Habibatul Ilmiyah, S. Andarini, Tony Suharsono","doi":"10.21776/ub.jkb.2022.032.01.11","DOIUrl":"https://doi.org/10.21776/ub.jkb.2022.032.01.11","url":null,"abstract":"The theory of planned behavior states that intention is the best predictor of behavior. The intention to perform a behavior is determined by a person's attitude, subjective norms, and perceived behavioral control. As volunteers in the health sector, volunteers of the Indonesian Red Cross (PMI) have been equipped with knowledge and skills regarding the role of an OHCA bystander. Besides, the intentions of PMI volunteers greatly affect a person's tendency to be willing or unwilling to become an OHCA bystander. This study aims to apply the theory of planned behavior in identifying the factors that influence the intentions of PMI volunteers in acting as OHCA bystanders and the dominant factors that affect intentions. This study used an observational research type with a cross-sectional approach. The respondents in this study were 105 PMI volunteer members in Tuban Regency, which were conducted using the purposive sampling technique. In determining the most dominant factor that influenced intention, ordinal logistic regression analysis was used in which it was shown that the variable used in the last modeling analysis stage was the subjective norm (OR= 6.19). Based on the results of the analysis, it can be concluded that subjective norms are the most predictor factor that influences intentions.","PeriodicalId":17705,"journal":{"name":"Jurnal Kedokteran Brawijaya","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82854764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Risk Factors for Mortality Due to Covid-19: A Case Study at a Distric Hospital in March-September 2020 2019冠状病毒病死率的危险因素:以2020年3月至9月某地区医院为例

Jurnal Kedokteran Brawijaya Pub Date : 2022-04-11 DOI: 10.21776/ub.jkb.2022.032.01.14

Luthfiana Husnaini Utami, Dyah Yulia Ariani, Oskar Renagalih Amarta

{"title":"Risk Factors for Mortality Due to Covid-19: A Case Study at a Distric Hospital in March-September 2020","authors":"Luthfiana Husnaini Utami, Dyah Yulia Ariani, Oskar Renagalih Amarta","doi":"10.21776/ub.jkb.2022.032.01.14","DOIUrl":"https://doi.org/10.21776/ub.jkb.2022.032.01.14","url":null,"abstract":"The Covid-19 pandemic, which becomes a global health problem, has widely impacted not only health but also social, economic, and politics in Indonesia. Previous studies have indicated that the patient's prognosis is influenced by the degree of disease, age, gender, and comorbidities. District hospital in Bojonegoro is a Covid-19 referral hospital and 37,1 % of patients who died in march-september 2020. This study was conducted to identify risk factors for death in patients with Covid-19 in hospital so we can reduce casa fatality rate in district hospital in Bojonegoro. The independent variables in the study were age, gender, and comorbid status, while the dependent variable was the output status (recovered or deceased). The study was conducted at a private hospital in East Java in October 2020 on 104 patients as subjects. Data were analyzed using the chi-square test. The results show that all the factors studied, age p = 0.006, gender p = 0.050, and comorbid status p = 0.001, have a statistically significant relationship with mortality. In short, at this hospital, advanced age, male gender, and comorbidities are the risk factors for Covid-19 death.","PeriodicalId":17705,"journal":{"name":"Jurnal Kedokteran Brawijaya","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84904860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of 0.1% Retinol Serum and Astaxanthin Gel on Skin Photoaging 0.1%视黄醇血清和虾青素凝胶对皮肤光老化的影响

Jurnal Kedokteran Brawijaya Pub Date : 2022-04-09 DOI: 10.21776/ub.jkb.2022.032.01.12

Boedhy Setyanto, Sinta Murlistyarini, Dea Florensia

{"title":"Effectiveness of 0.1% Retinol Serum and Astaxanthin Gel on Skin Photoaging","authors":"Boedhy Setyanto, Sinta Murlistyarini, Dea Florensia","doi":"10.21776/ub.jkb.2022.032.01.12","DOIUrl":"https://doi.org/10.21776/ub.jkb.2022.032.01.12","url":null,"abstract":"Skin photoaging is cumulative skin damage due to chronic environmental exposure, especially ultraviolet (UV) light, which interferes with the keratinocyte and fibroblast syntheses by matrix metalloproteinases (MMP). Retinol can improve wrinkles, pigmentation, elasticity, firmness, brightness, and various signs of photoaging on the skin. Astaxanthin is a powerful antioxidant that protects the skin from UV rays, inhibits MMP, and stimulates collagen production. This case report presents 2 cases of women complaining about deep skin wrinkles, dullness, and looseness. Physical examination in the facial region revealed wrinkles when resting in the first patient and wrinkles during motion in the second patient. The first patient was diagnosed Glogau III photoaging, while the second patient was diagnosed Glogau II photoaging. Both patients received astaxanthin gel therapy and SPF 33 sunscreen cream every morning, as well as 0.1% retinol serum every night. There was an improvement after six weeks. Astaxanthin and retinol 0.1% can be used as photoaging therapy. Adequate use of photoprotection is also necessary to prevent the worsening of photoaging.","PeriodicalId":17705,"journal":{"name":"Jurnal Kedokteran Brawijaya","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75392675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship of Depression and Sleep Quality among North Jakarta Medical Students during the COVID-19 Pandemic 新冠肺炎大流行期间北雅加达医科学生抑郁与睡眠质量的关系

Jurnal Kedokteran Brawijaya Pub Date : 2022-04-09 DOI: 10.21776/ub.jkb.2022.032.01.9

Annabella Naida Tanusetiawan, Surilena Surilena, Nelly Tina Widjaja, Dharmady Agus

{"title":"Relationship of Depression and Sleep Quality among North Jakarta Medical Students during the COVID-19 Pandemic","authors":"Annabella Naida Tanusetiawan, Surilena Surilena, Nelly Tina Widjaja, Dharmady Agus","doi":"10.21776/ub.jkb.2022.032.01.9","DOIUrl":"https://doi.org/10.21776/ub.jkb.2022.032.01.9","url":null,"abstract":"Medical students with high academic load have had elevated baseline rates of depression and poor sleep quality. During the COVID-19 pandemic, medical students are more susceptible to depression and poor sleep quality. This study aimed to analyze depression and sleep quality among medical students at the School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia (FKIK UAJ) during the COVID-19 pandemic. A cross-sectional study was conducted among pre-clinical and clinical students of FKIK UAJ academic year 2020/2021. Respondents were selected through proportional systematic random sampling to fulfill the Patient Health Questionnaire-9 (PHQ-9) and Pittsburgh Sleep Quality Index (PSQI) for depression and sleep quality. The data were analyzed using Mann Whitney U-Test. There were 63.3% of 635 respondents with depression, in which 39.4% respondents had mild depression, 14.2% respondents with moderate depression, and 9.8% respondents with severe depression. There were 59,2% of respondents with poor sleep quality. Depression was highest in females (67.2%) and pre-clinical stage of 2020 intake year (74.6%), and among clinical level students of 2018 (56%) and 2019 (53.9%) intake year. Poor sleep quality was also highest in females (62.8%) and pre-clinical 2020 intake year (69.8%), and among clinical level students of 2018 (53%) and 2019 (51.9%) intake year. The Mann-Whitney U-test showed a significant difference between depression level and sleep quality in pre-clinical and clinical students of FKIK UAJ during the COVID-19 pandemic (p value=0.000). Depression and sleep quality among medical students of FKIK UAJ during the COVID-19 pandemic were significantly associated.","PeriodicalId":17705,"journal":{"name":"Jurnal Kedokteran Brawijaya","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85176626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of TWIST (Testicular Workup for Ischemia and Suspected Torsion) Score System for Differential Diagnosis in Acute Scrotum in Tertiary Teaching Hospital 三级教学医院急性阴囊鉴别诊断TWIST(睾丸缺血及疑似扭转检查)评分系统的验证

Jurnal Kedokteran Brawijaya Pub Date : 2022-04-09 DOI: 10.21776/ub.jkb.2022.032.01.4

Nyoman Gede Prayudi, B. Daryanto, Taufiq Nur Budaya

{"title":"Validation of TWIST (Testicular Workup for Ischemia and Suspected Torsion) Score System for Differential Diagnosis in Acute Scrotum in Tertiary Teaching Hospital","authors":"Nyoman Gede Prayudi, B. Daryanto, Taufiq Nur Budaya","doi":"10.21776/ub.jkb.2022.032.01.4","DOIUrl":"https://doi.org/10.21776/ub.jkb.2022.032.01.4","url":null,"abstract":"The acute scrotum is a common urological emergency and has a broad differential diagnosis. There is no clear consensus on a particular algorithm to follow in the diagnosis of testicular torsion. Testicular Workup for Ischemia and Suspected Torsion (TWIST) Score, a risk scoring system based on signs and symptoms, can be invaluable in managing patients with the acute scrotum, specifically testicular torsion. This study aimed to evaluate the effectiveness of the TWIST scoring system for differential diagnosis of acute scrotal patients. The study was conducted using secondary data, medical records from 111 male patients diagnosed with acute scrotum in Saiful Anwar General Hospital Malang between January 2015 and December 2018. Data about the onset of pain, first contact, history, physical examination findings, any adjunct test performed, and intra-operative findings were collected. The effectiveness of the TWIST score in diagnosing testicular torsion was determined by calculating the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). Of the 111 patients, 43 patients (38.7%) had testicular torsion. The mean age was 17.49 (6.69) years. A total of 39 patients were classified as high risk as per the TWIST Score with cut point 5 had 83.7% sensitivity, 95.6% specificity, 92.3% positive predictive value (PPV), and 90.3% negative predictive value (NPV). The area under the curve was 0.93. The use of the TWIST Score in clinical practice can accurately determine high-risk patients who can proceed straight to the operating theatre without the need for an ultrasound.","PeriodicalId":17705,"journal":{"name":"Jurnal Kedokteran Brawijaya","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79433045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Baseline Stroke Severity as a Predictor of 30-Day Post-Ischemic Stroke Disability Outcome 基线脑卒中严重程度作为缺血性脑卒中后30天残疾结局的预测因子

Jurnal Kedokteran Brawijaya Pub Date : 2022-04-09 DOI: 10.21776/ub.jkb.2022.032.01.6

Diana Teresa, R. Pinzon, Sugianto Adisaputro

{"title":"Baseline Stroke Severity as a Predictor of 30-Day Post-Ischemic Stroke Disability Outcome","authors":"Diana Teresa, R. Pinzon, Sugianto Adisaputro","doi":"10.21776/ub.jkb.2022.032.01.6","DOIUrl":"https://doi.org/10.21776/ub.jkb.2022.032.01.6","url":null,"abstract":"More than 50% of patients who survived stroke have a chronic disability. The National Institute of Health Stroke Scale (NIHSS) is a scoring system to determine the neurologic deficit of a stroke patient. This study analyzed stroke severity based on baseline NIHSS score as a determinant for 30-day post-ischemic stroke disability. This study method uses a retrospective cohort design based on medical records and stroke registry of ischemic stroke patients in Bethesda Hospital Yogyakarta. During admission, the predictive factors for the disability of the study subjects were evaluated. The baseline NIHSS assessment score was measured at 1x24 hours after admission. Disability was measured using a simplified modified Rankin Scale questionnaire (smRSq) Indonesian version at 30-day post-ischemic stroke. Statistical analysis includes univariate, bivariate, and logistic regression multivariate data analysis. The subjects were 84 patients with ischemic stroke. Disability at 30-day post-ischemic stroke occurred in 22 patients (26.2%). Logistic regression multivariate analysis show that Neutrophil to Lymphocyte Ratio (NLR) (RR: 4.488, CI: 1.873–10.756, p: 0.001) and baseline NIHSS score (RR: 28.563, CI: 2.891–282.181, p: 0.004) together significantly affect the mRS of 30-day post-ischemic stroke. Patients admitted with a higher baseline NIHSS score have a 28.5 fold risk for a worse functional outcome than those with lower baseline NIHSS scores. Stroke severity based on baseline NIHSS score is a determinant factor for disability in patients at 30-day post-ischemic stroke.","PeriodicalId":17705,"journal":{"name":"Jurnal Kedokteran Brawijaya","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77669008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between Assertive Communication and Cyber-bullying in Adolescents 青少年自信沟通与网络欺凌的关系

Jurnal Kedokteran Brawijaya Pub Date : 2021-08-31 DOI: 10.21776/ub.jkb.2021.031.04.7

Ira Kusumawaty, Yunike Yunike, Sujati Ni Ketut

{"title":"Relationship between Assertive Communication and Cyber-bullying in Adolescents","authors":"Ira Kusumawaty, Yunike Yunike, Sujati Ni Ketut","doi":"10.21776/ub.jkb.2021.031.04.7","DOIUrl":"https://doi.org/10.21776/ub.jkb.2021.031.04.7","url":null,"abstract":"The mandatory use of online facilities during the Covid-19 period has a great opportunity to increase the problem of cyber bullying at all levels of education. The concept of assertiveness cannot be separated from cyber bullying and it is known that communicating assertively can prevent cyber bullying even though it is difficult to implement. The complexity of the psychological problems of victims of cyber bullying requires comprehensive management. This analytical descriptive study with a cross sectional approach aims to analyze the relationship between assertive communication and cyber bullying by involving 151 student participants and high school students in Palembang. The data was collected using an assertive scale and a cyber-bullying scale, which was distributed online using a Google form. From Kendall's tau-b statistical test, it is known that there is a relationship between assertive communication and cyber bullying (p=0.026). It is recommended that the education sector implement self-awareness, empathy, assertive communication and conflict resolution training to prevent the increasing number of cyber bullying's victim. The academic and managerial sectors are expected to facilitate promotion through educational media about using online facilities intelligently by respecting human dignity.","PeriodicalId":17705,"journal":{"name":"Jurnal Kedokteran Brawijaya","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85847440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Factors Associated with Fatigue in Chronic Kidney Disease Patients Undergoing Hemodialysis: A Systematic Review 慢性肾脏病血液透析患者疲劳相关因素:系统综述

Jurnal Kedokteran Brawijaya Pub Date : 2021-08-31 DOI: 10.21776/ub.jkb.2021.031.04.12

F. Prastiwi, T. A. Wihastuti, D. D. S. L. Ismail

引用次数: 0

Clinical Response of Convalescent Plasma Therapy in COVID-19 Patients in Dr. Saiful Anwar General Hospital 安华总医院新冠肺炎恢复期血浆治疗临床疗效观察

Jurnal Kedokteran Brawijaya Pub Date : 2021-08-31 DOI: 10.21776/ub.jkb.2021.031.04.5

Niniek Burhan, H. P. Brahmantyo, Djoko Heri Hermanto, P. Arsana

引用次数: 0