Kidney international. Supplement最新文献_第10页

Outcome studies of continuous renal replacement therapy in the intensive care unit. 重症监护病房持续肾替代治疗的结局研究。

Kidney international. Supplement Pub Date : 1998-05-01

W Silvester

引用次数: 0

Electrolyte disorders and substitution fluid in continuous renal replacement therapy. 持续肾替代治疗中的电解质紊乱和替代液。

Kidney international. Supplement Pub Date : 1998-05-01

F Locatelli, G Pontoriero, S Di Filippo

{"title":"Electrolyte disorders and substitution fluid in continuous renal replacement therapy.","authors":"F Locatelli, G Pontoriero, S Di Filippo","doi":"","DOIUrl":"","url":null,"abstract":"Electrolyte balances during acute renal failure treated with continuous convective techniques, such as continuous arteriovenous hemofiltration (CAVH) and its pumped variants, are largely dependent on the eloctrolyte plasma concentration available for ultrafiltration, the ultrafiltration rate and the composition of the replacement solution. As blood sodium concentrations measured by potentiometry (Na +P) and the total ultrafiltrate sodium concentration are very similar, Na +P can be taken as the value of ultrafilterable sodium when choosing the correct sodium concentration in the substitution fluid. In CAVH, the ultrafiltrate contains about 3 m Eq/liter of calcium and 1 m Eq/liter of magnesium that must be replaced by the substitution fluid in order to prevent hypocalcemia and hypomagnesemia. In addition, if plasma potassium levels are normal, 3 to 4 mEq/liter of potassium should be added to the replacement fluid to avoid hypokalemia. Although convection and diffusion are combined in continuous hemodialysis, solute transport is largely mediated by convection; however, the net removal of sodium and calcium is significantly influenced by their concentrations in the dialysate, and the risk of hypomagnesemia and hypokalemia can be attenuated by adjusting magnesium and potassium concentrations in the dialysis solution to levels near to the plasma water values. Since critically ill patients are prone to developing dialysis-induced hypophosphatemia, phosphorous must be monitored and supplemented if necessary, Since CRRT works continuously, serious derangement in fluid and electrolyte homeostasis may occur in the absence of careful prescription and extremely vigilant monitoring.","PeriodicalId":17704,"journal":{"name":"Kidney international. Supplement","volume":"66 ","pages":"S151-5"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20495041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drug dosing adjustments during continuous renal replacement therapies. 持续肾替代治疗期间的药物剂量调整。

Kidney international. Supplement Pub Date : 1998-05-01

T A Golper, M A Marx

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The critically ill patient. 那个病危的病人。

Kidney international. Supplement Pub Date : 1998-05-01

M R Pinsky

引用次数: 0

Continuous plasma filtration coupled with sorbents. 连续等离子体过滤结合吸附剂。

Kidney international. Supplement Pub Date : 1998-05-01

C Tetta, J M Cavaillon, G Camussi, F G Lonnemann, A Brendolan, C Ronco

{"title":"Continuous plasma filtration coupled with sorbents.","authors":"C Tetta, J M Cavaillon, G Camussi, F G Lonnemann, A Brendolan, C Ronco","doi":"","DOIUrl":"","url":null,"abstract":"An in vitro system composed of a plasma separation membrane coupled with natural (charcoal) or synthetic (Amberlite, Amberchrome) types of sorbents was evaluated for the simultaneous removal of proinflammatory cytokines (TNF-alpha, IL-1 beta and IL-8) and cytokine antagonists [interleukin (IL)-1 receptor antagonist (IL-1Ra), soluble tumor necrosis factor-alpha (TNF-alpha) receptor I and II (sTNFR I and II)] in whole blood spiked with bacterial lipopolysaccharide (LPS). These studies showed that plasma filtration rather than ultrafiltration significantly increased the clearance of all cytokines, particularly TNF-alpha, and the synthetic (Amberlite-type of resin) but not natural (uncoated charcoal) membrane could extensively absorb almost 100% of plasma filtered IL-Ra, IL-1 beta and IL-8, but only 40% of TNF-alpha. Other synthetic (Amberchrome) membranes could also effectively (80%) remove TNF-alpha. In the complex scenario of sepsis, the simultaneous removal of excess proinflammatory and/or immunomodulatory mediators may play a role in reducing the hemodynamic alterations, thus resulting in enhanced patient survival. Whether this occurs in the human setting awaits the results of an ongoing clinical investigation.","PeriodicalId":17704,"journal":{"name":"Kidney international. Supplement","volume":"66 ","pages":"S186-9"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20496210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of diuretics in the acute care setting. 利尿剂在急症护理中的应用。

Kidney international. Supplement Pub Date : 1998-05-01

J A Kellum

引用次数: 0

Role of soluble mediators in sepsis and renal failure. 可溶性介质在败血症和肾衰竭中的作用。

Kidney international. Supplement Pub Date : 1998-05-01

G Camussi, C Ronco, G Montrucchio, G Piccoli

引用次数: 0

The hemolytic uremic syndrome. 溶血性尿毒症综合征。

Kidney international. Supplement Pub Date : 1998-05-01

G Remuzzi, P Ruggenenti