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The first reported cases of meat allergy following tick bites in the UK. 英国首次报道蜱虫叮咬后肉类过敏病例。
JRSM Open Pub Date : 2021-04-28 eCollection Date: 2021-04-01 DOI: 10.1177/2054270421996131
Rhea A Bansal, Sameer Bahal, Rachael O'Brien, Joanne Miller, Amolak S Bansal, Patrick Fk Yong
{"title":"The first reported cases of meat allergy following tick bites in the UK.","authors":"Rhea A Bansal,&nbsp;Sameer Bahal,&nbsp;Rachael O'Brien,&nbsp;Joanne Miller,&nbsp;Amolak S Bansal,&nbsp;Patrick Fk Yong","doi":"10.1177/2054270421996131","DOIUrl":"https://doi.org/10.1177/2054270421996131","url":null,"abstract":"<p><p>Allergic reactions frequently involve the production of immunoglobulin E (IgE) antibodies to proteins. However, reactions directed against carbohydrate moieties are increasingly being recognised. Tick bites can contribute to the development of immunoglobulin E to the galactose-1,3-galactose (alpha-gal) moiety on tick salivary proteins. These IgE molecules can cross-react with alpha-gal found in red meats, causing Type I IgE-mediated hypersensitivity reactions to these foods. We present three cases of delayed reactions to beef, pork and lamb in patients with prior tick bites and in the presence of a positive-specific IgE to alpha-gal. Patients were advised to avoid red meat consumption and to carry emergency treatment in the form of anti-histamines with or without adrenaline autoinjector devices. This is the first published report of red meat allergy caused by tick bites suffered in the UK.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"12 4","pages":"2054270421996131"},"PeriodicalIF":0.0,"publicationDate":"2021-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2054270421996131","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38988981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare mediastinal thymic cyst infection without predisposing disease: a case report. 罕见无易感疾病的纵隔胸腺囊肿感染1例。
JRSM Open Pub Date : 2021-04-14 eCollection Date: 2021-04-01 DOI: 10.1177/2054270421991801
Ayham Alzahran, Baraa Shebli, Sidra Dabbas, Joudi Sawas, Joud Khalili, M Zaki Karzoun, Areej Alhasan, Manar Abdullah
{"title":"Rare mediastinal thymic cyst infection without predisposing disease: a case report.","authors":"Ayham Alzahran,&nbsp;Baraa Shebli,&nbsp;Sidra Dabbas,&nbsp;Joudi Sawas,&nbsp;Joud Khalili,&nbsp;M Zaki Karzoun,&nbsp;Areej Alhasan,&nbsp;Manar Abdullah","doi":"10.1177/2054270421991801","DOIUrl":"https://doi.org/10.1177/2054270421991801","url":null,"abstract":"Ayham Alzahran , Baraa Shebli , Sidra Dabbas, Joudi Sawas, Joud Khalili, M Zaki Karzoun, Areej Alhasan and Manar Abdullah Faculty of Medicine, University of Aleppo, 15310 Aleppo, Syria Department of Pathology, Aleppo University Hospital, University of Aleppo, 15310 Aleppo, Syria Department of Pediatrics, Aleppo University Hospital, University of Aleppo, 15310 Aleppo, Syria Corresponding author: Baraa Shebli. Email: bshebli@gmail.com","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"12 4","pages":"2054270421991801"},"PeriodicalIF":0.0,"publicationDate":"2021-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2054270421991801","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38968070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Duplex ultrasound in the evaluation of venous and arterial thoracic outlet syndrome. 双工超声对胸廓静脉和动脉综合征的评价。
JRSM Open Pub Date : 2021-03-22 eCollection Date: 2021-03-01 DOI: 10.1177/2054270420983101
Jian Hu, Robert Biederman, Kartikeya Kashyap, John Travis Wilson, Victor Farah, Todd Franco, Vinh Nguyen
{"title":"Duplex ultrasound in the evaluation of venous and arterial thoracic outlet syndrome.","authors":"Jian Hu,&nbsp;Robert Biederman,&nbsp;Kartikeya Kashyap,&nbsp;John Travis Wilson,&nbsp;Victor Farah,&nbsp;Todd Franco,&nbsp;Vinh Nguyen","doi":"10.1177/2054270420983101","DOIUrl":"https://doi.org/10.1177/2054270420983101","url":null,"abstract":"<p><p>We are reporting a case of thoracic outlet syndrome and the value of duplex in the diagnosis of this syndrome.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"12 3","pages":"2054270420983101"},"PeriodicalIF":0.0,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2054270420983101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25558062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
A rare cause of acute liver failure due to haemophagocytic lymphohistiocytosis secondary to diffuse large B-cell lymphoma. 弥漫性大b细胞淋巴瘤继发的嗜血球性淋巴组织细胞增多症是一种罕见的急性肝衰竭病因。
JRSM Open Pub Date : 2021-03-02 eCollection Date: 2021-03-01 DOI: 10.1177/2054270420983623
Andrew Coppola, Chia Chey, Emma O'Donovan, Monira Rahman
{"title":"A rare cause of acute liver failure due to haemophagocytic lymphohistiocytosis secondary to diffuse large B-cell lymphoma.","authors":"Andrew Coppola,&nbsp;Chia Chey,&nbsp;Emma O'Donovan,&nbsp;Monira Rahman","doi":"10.1177/2054270420983623","DOIUrl":"https://doi.org/10.1177/2054270420983623","url":null,"abstract":"<p><p>Acute liver failure is a life-threatening condition commonly caused by drug-induced hepatotoxicity or viral hepatitides. However, there are a number of rarer causes such as haemophagocytic lymphohistiocytosis. Haemophagocytic lymphohistiocytosis is a syndrome of uncontrolled immune cell activation, triggered by infection or malignancy, which carries a high mortality. Whilst mild to moderate liver injury is commonly seen with haemophagocytic lymphohistiocytosis, acute liver failure has rarely been reported in adults. We present a case of a 74-year-old man with acute liver failure secondary to haemophagocytic lymphohistiocytosis triggered by undiagnosed large B-cell lymphoma. Initially treated for biliary sepsis, there was a delay in the diagnosis of haemophagocytic lymphohistiocytosis and despite initiating chemotherapy, he died soon after. This case highlights the importance of considering haemophagocytic lymphohistiocytosis as a rare cause of acute liver failure, as given the life-threatening potential of haemophagocytic lymphohistiocytosis, a prompt diagnosis may allow early initiation of chemotherapy for any chance of survival.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"12 3","pages":"2054270420983623"},"PeriodicalIF":0.0,"publicationDate":"2021-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2054270420983623","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25476736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Mistaken administration of a repeat loading dose of Degarelix leading to acute psychosis. 错误地服用重复负荷剂量的Degarelix导致急性精神病。
JRSM Open Pub Date : 2021-02-19 eCollection Date: 2021-02-01 DOI: 10.1177/2054270420983105
Musaab Hamdoon, Maria Satchi, Fay Fawke, Sanjeev Madaan
{"title":"Mistaken administration of a repeat loading dose of Degarelix leading to acute psychosis.","authors":"Musaab Hamdoon,&nbsp;Maria Satchi,&nbsp;Fay Fawke,&nbsp;Sanjeev Madaan","doi":"10.1177/2054270420983105","DOIUrl":"https://doi.org/10.1177/2054270420983105","url":null,"abstract":"<p><p>Advanced and metastatic prostate cancer is often managed with hormonal blockage. Luteinising hormone-releasing hormone antagonists achieve rapid testosterone suppression and are used for the treatment of advanced or metastatic prostate cancer. Degarelix is a luteinising hormone-releasing hormone antagonist and is given as a loading dose, followed by a monthly maintenance dose. We report a case where a patient was inadvertently given a second loading dose of Degarelix that resulted in acute psychosis in the form of panic attacks, delusions, suicidal thoughts, insomnia and some visual hallucinations, which are not reported as side-effects of Degarelix.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"12 2","pages":"2054270420983105"},"PeriodicalIF":0.0,"publicationDate":"2021-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2054270420983105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25445123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Diagnostic and surgical challenges in disseminated tuberculosis presenting as acute abdomen during COVID-19 pandemic. COVID-19大流行期间表现为急腹症的播散性结核病的诊断和手术挑战
JRSM Open Pub Date : 2021-02-11 eCollection Date: 2021-02-01 DOI: 10.1177/2054270420985736
Deepak Rajput, Shashank Kumar, Ankit Rai, S Chezhian
{"title":"Diagnostic and surgical challenges in disseminated tuberculosis presenting as acute abdomen during COVID-19 pandemic.","authors":"Deepak Rajput,&nbsp;Shashank Kumar,&nbsp;Ankit Rai,&nbsp;S Chezhian","doi":"10.1177/2054270420985736","DOIUrl":"https://doi.org/10.1177/2054270420985736","url":null,"abstract":"<p><p>Due to the lack of much insight into the SARS-CoV-2 and overlapping symptoms and signs with other respiratory infections, diagnosis and management is often challenging in chest ailments particularly tuberculosis.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"12 2","pages":"2054270420985736"},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2054270420985736","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25408851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Necrotic plaques in an elderly male. 老年男性的坏死斑块。
JRSM Open Pub Date : 2021-02-11 eCollection Date: 2021-02-01 DOI: 10.1177/2054270420981452
Bindi Gaglani, Ian Logan, Faris Kubba
{"title":"Necrotic plaques in an elderly male.","authors":"Bindi Gaglani,&nbsp;Ian Logan,&nbsp;Faris Kubba","doi":"10.1177/2054270420981452","DOIUrl":"https://doi.org/10.1177/2054270420981452","url":null,"abstract":"Reactive perforating collagenosis is commonly recognised as an unusual form of transepithelial elimination of collagen and elastin fibres which are extruded through the epidermis in patients with a genetic predisposition or underlying diseases, such as diabetes mellitus or renal diseases. We present the unusual case of an 87-year-old diabetic male with a giant form of reactive perforating collagenosis and review the available literature.","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"12 2","pages":"2054270420981452"},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2054270420981452","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25408850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Splenic flexure colonic lipoma causing intussusception. 脾脏弯曲性结肠脂肪瘤引起肠套叠。
JRSM Open Pub Date : 2021-01-11 eCollection Date: 2021-01-01 DOI: 10.1177/2054270420983088
Moustafa Moussally, Imad Mokalled, Faek Jamali, Mohamad J Khalife
{"title":"Splenic flexure colonic lipoma causing intussusception.","authors":"Moustafa Moussally,&nbsp;Imad Mokalled,&nbsp;Faek Jamali,&nbsp;Mohamad J Khalife","doi":"10.1177/2054270420983088","DOIUrl":"https://doi.org/10.1177/2054270420983088","url":null,"abstract":"<p><p>Colonic lipomas are rare benign tumours that are usually asymptomatic. However, giant colonic lipomas tend to be symptomatic and can occasionally result in intussusception and intermittent colonic obstruction. As adult intussusception is an uncommon occurrence, the identification of the underlying aetiology is essential due to its high association with malignancy. Computed Tomography remains the tool of choice for the diagnosis of colonic lipomas. Surgical excision remains the mainstay treatment of giant symptomatic colonic lipomas. We hereby present the case of a 51-year-old male found to have a colonic lipoma causing recurrent intussusception. We discuss the approach, diagnostic tools and available treatment modalities for colonic lipomas. We also provide a brief literature review of intussusception in adults.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"12 1","pages":"2054270420983088"},"PeriodicalIF":0.0,"publicationDate":"2021-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2054270420983088","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38854892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Optical coherence tomography significance in managing complex neurofibromatosis 2-related papilledema: Report of a case. 光学相干断层扫描在处理复杂神经纤维瘤病2相关乳头状水肿中的意义:1例报告。
JRSM Open Pub Date : 2021-01-11 eCollection Date: 2021-01-01 DOI: 10.1177/2054270420981454
Giacomo Maria Bacci, Flavio Giordano, Iacopo Sardi, Gareth Evans, Omar Pathmanaban, Carla Fonte, Franco Trabalzini, Sergio Nappini, Regina Mura, Roberto Caputo
{"title":"Optical coherence tomography significance in managing complex neurofibromatosis 2-related papilledema: Report of a case.","authors":"Giacomo Maria Bacci,&nbsp;Flavio Giordano,&nbsp;Iacopo Sardi,&nbsp;Gareth Evans,&nbsp;Omar Pathmanaban,&nbsp;Carla Fonte,&nbsp;Franco Trabalzini,&nbsp;Sergio Nappini,&nbsp;Regina Mura,&nbsp;Roberto Caputo","doi":"10.1177/2054270420981454","DOIUrl":"https://doi.org/10.1177/2054270420981454","url":null,"abstract":"<p><p>This case describes the strong utility of optical coherence tomography in multidisciplinary management of a complex case of type 2 neurofibromatosis.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"12 1","pages":"2054270420981454"},"PeriodicalIF":0.0,"publicationDate":"2021-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2054270420981454","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38854891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
SARS-CoV-2 (COVID-19) PCR cycle threshold: can it help in the timing of urgent cardiac surgery? SARS-CoV-2 (COVID-19) PCR周期阈值:能否帮助确定紧急心脏手术的时机?
JRSM Open Pub Date : 2020-12-24 eCollection Date: 2020-12-01 DOI: 10.1177/2054270420977365
Abdulaziz Alkhulaifi, Shady Mohammed, Hafeez Lone, Mohd Wani, Bassam Shoman, Mawahib Elhassan, Asmaa Althani, Cornelia S Carr
{"title":"SARS-CoV-2 (COVID-19) PCR cycle threshold: can it help in the timing of urgent cardiac surgery?","authors":"Abdulaziz Alkhulaifi,&nbsp;Shady Mohammed,&nbsp;Hafeez Lone,&nbsp;Mohd Wani,&nbsp;Bassam Shoman,&nbsp;Mawahib Elhassan,&nbsp;Asmaa Althani,&nbsp;Cornelia S Carr","doi":"10.1177/2054270420977365","DOIUrl":"https://doi.org/10.1177/2054270420977365","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic has resulted in a significant reduction in urgent cardiac surgery due to concerns about safety for both patients and care givers. The timing of safe cardiac surgery is yet to be clarified in the setting of COVID-19 diagnosis.</p><p><strong>Methods: </strong>Due to the urgency of the cardiac conditions on presentation, we have operated on four patients who exhibited the spectrum of COVID-19 disease from asymptomatic to severe COVID-19 pneumonia. With the evolving knowledge about SARS-CoV-2 and its genetic determinants as well as the cycle threshold levels obtained from real-time reverse transcription polymerase chain reaction, we have attempted to develop a strategy to deal with these patients.</p><p><strong>Results: </strong>All four patients underwent urgent cardiac surgery following a thorough evaluation and multidisciplinary team approach with guidance based on the virus cycle threshold values obtained by reverse transcription polymerase chain reaction.</p><p><strong>Conclusion: </strong>We have shown that, with thorough preparations, consideration of the significance of the cycle threshold obtained on reverse transcription polymerase chain reaction and meticulous timing, COVID-19 diagnosed patients may undergo open heart surgery safely.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"11 12","pages":"2054270420977365"},"PeriodicalIF":0.0,"publicationDate":"2020-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2054270420977365","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38854890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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