JRSM OpenPub Date : 2024-03-11eCollection Date: 2024-03-01DOI: 10.1177/20542704241232818
Erin Riley, Louise E Smith, G James Rubin, Lisa Woodland
{"title":"Why did the UK public not adequately understand the symptoms of COVID-19? An analysis of UK Government statements from 3rd March 2020 to 21st February 2022.","authors":"Erin Riley, Louise E Smith, G James Rubin, Lisa Woodland","doi":"10.1177/20542704241232818","DOIUrl":"10.1177/20542704241232818","url":null,"abstract":"","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"15 3","pages":"20542704241232818"},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10929041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140119880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JRSM OpenPub Date : 2024-02-21eCollection Date: 2024-02-01DOI: 10.1177/20542704231222735
Hafeez U Lone, Shady Ashraf, Cornelia S Carr, Issam Bossom, Abdulaziz M Alkhulaifi
{"title":"Infected Takayasu's arteritis presenting with aortic perforation.","authors":"Hafeez U Lone, Shady Ashraf, Cornelia S Carr, Issam Bossom, Abdulaziz M Alkhulaifi","doi":"10.1177/20542704231222735","DOIUrl":"10.1177/20542704231222735","url":null,"abstract":"<p><p>We want to remind Physicians that unusual conditions can present in unusual ways and to keep an open mind always.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"15 2","pages":"20542704231222735"},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10883127/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139931698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JRSM OpenPub Date : 2024-02-01DOI: 10.1177/20542704231222718
Claudia Stöllberger, Josef Finsterer
{"title":"Atrio-oesophageal fistula after radiofrequency ablation of atrial fibrillation misinterpreted as COVID-19 infection.","authors":"Claudia Stöllberger, Josef Finsterer","doi":"10.1177/20542704231222718","DOIUrl":"10.1177/20542704231222718","url":null,"abstract":"<p><p>Awareness of the various clinical manifestations and diagnostic pitfalls in patients with atrio-oesophageal fistula is necessary among healthcare professionals.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"15 2","pages":"20542704231222718"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10836140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139681324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JRSM OpenPub Date : 2024-01-14eCollection Date: 2024-01-01DOI: 10.1177/20542704231217887
Gary Abel, Rob Froud, Emma Pitchforth, Bethan Treadgold, Lucy Hocking, Jon Sussex, Marc Elliott, John Campbell
{"title":"Informing the development of a scoring system for National Health Service Clinical Impact Awards; a Delphi process and simulated scoring exercise.","authors":"Gary Abel, Rob Froud, Emma Pitchforth, Bethan Treadgold, Lucy Hocking, Jon Sussex, Marc Elliott, John Campbell","doi":"10.1177/20542704231217887","DOIUrl":"10.1177/20542704231217887","url":null,"abstract":"<p><strong>Objectives: </strong>To establish principles informing a new scoring system for the UK's Clinical Impact Awards and pilot a system based on those principles.</p><p><strong>Design: </strong>A three-round online Delphi process was used to generate consensus from experts on principles a scoring system should follow. We conducted a shadow scoring exercise of 20 anonymised, historic applications using a new scoring system incorporating those principles.</p><p><strong>Setting: </strong>Assessment of clinical excellence awards for senior doctors and dentists in England and Wales.</p><p><strong>Participants: </strong>The Delphi panel comprised 45 members including clinical excellence award assessors and representatives of professional bodies. The shadow scoring exercise was completed by 24 current clinical excellence award assessors.</p><p><strong>Main outcome measures: </strong>The Delphi panel rated the appropriateness of a series of items. In the shadow scoring exercise, a novel scoring system was used with each of five domains rated on a 0-10 scale.</p><p><strong>Results: </strong>Consensus was achieved around principles that could underpin a future scoring system; in particular, a 0-10 scale with the lowest point on the scale reflecting someone operating below the expectations of their job plan was agreed as appropriate. The shadow scoring exercise showed similar levels of reliability between the novel scoring system and that used historically, but with potentially better distinguishing performance at higher levels of performance.</p><p><strong>Conclusions: </strong>Clinical excellence awards represent substantial public spending and thus far the deployment of these funds has lacked a strong evidence base. We have developed a new scoring system in a robust manner which shows improvements over current arrangements.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"15 1","pages":"20542704231217887"},"PeriodicalIF":0.0,"publicationDate":"2024-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10790597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139477967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JRSM OpenPub Date : 2024-01-01DOI: 10.1177/20542704231217888
Ereel Ayubi, R. Lyus, P. Brhlikova, Allyson M. Pollock
{"title":"A critical appraisal of the quality of data submitted by sub-Saharan African cancer registries to GLOBOCAN 2020","authors":"Ereel Ayubi, R. Lyus, P. Brhlikova, Allyson M. Pollock","doi":"10.1177/20542704231217888","DOIUrl":"https://doi.org/10.1177/20542704231217888","url":null,"abstract":"Objectives (a) To critically appraise the quality of data submitted by sub-Saharan African (SSA) cancer registries to GLOBOCAN 2020 and (b) compare the quality of data of the registries common to GLOBOCAN 2008 and 2020. Design Critical appraisal of cancer registry data quality using the Parkin and Bray framework. Setting and Participants GLOBOCAN 2020 cancer registry estimates for 46 countries in SSA. Forty-three registries in 31 (SSA) countries were identified from the GLOBCAN 2020 supplementary documents, of which data from 28 registries in 23 sub-Saharan African countries were publicly available. Main outcomes measures Data quality for 15 variables in four domains (comparability, validity, timeliness and completeness) were appraised using the Parkin and Bray framework. Results from the appraisal of GLOBOCAN 2020 sources were compared with previous findings for GLOBOCAN 2008. Results Compared with GLOBOCAN 2008, GLOBOCAN 2020 country coverage had increased from 21 to 31 countries with 15 countries having no established registries. Out of a total possible score of 15 for data quality, 18 of the 28 publicly available GLOBOCAN 2020 registries fulfilled a score of 5 or more compared with seven registries in GLOBOCAN 2008. Of the 17 registries common to GLOBOCAN 2008 and 2020, nine showed an improvement in data quality. Conclusion Country coverage and data quality have improved since GLOBOCAN 2008, however, overall data quality and coverage remain poor. GLOBOCAN 2020 estimates should be used with caution when allocating resources.","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"29 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139455981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JRSM OpenPub Date : 2023-12-15eCollection Date: 2023-12-01DOI: 10.1177/20542704231215970
Jesal Patel, Cai Neville, Raj Kumar, Elisabeth Grey-Davies, Renata Hutt, Fleur S van Dijk, Li Yuan Chan, Edward Walter
{"title":"Familial hepatic rupture in vascular Ehlers-Danlos syndrome in pregnancy with atypical thromboses.","authors":"Jesal Patel, Cai Neville, Raj Kumar, Elisabeth Grey-Davies, Renata Hutt, Fleur S van Dijk, Li Yuan Chan, Edward Walter","doi":"10.1177/20542704231215970","DOIUrl":"https://doi.org/10.1177/20542704231215970","url":null,"abstract":"<p><p>This case highlights the importance of genetic testing over fibroblast testing and presents the first published thromboelastometry data in vascular Ehlers-Danlos syndrome.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"14 12","pages":"20542704231215970"},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10725090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138806454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JRSM OpenPub Date : 2023-11-01DOI: 10.1177/20542704231205388
Michelle Lee, Ralitsa Baranowski, Aung Oo, David Waller
{"title":"A rare case of ‘ring-sling complex’ in a symptomatic adult patient: A left pulmonary artery sling with complete tracheal rings","authors":"Michelle Lee, Ralitsa Baranowski, Aung Oo, David Waller","doi":"10.1177/20542704231205388","DOIUrl":"https://doi.org/10.1177/20542704231205388","url":null,"abstract":"Pulmonary artery sling (PAS) is a rare congenital condition, in which the left pulmonary artery (LPA) originates from the right pulmonary artery instead of the main pulmonary artery. It courses between the oesophagus and the trachea, forming a sling and causes compression of both structures. We report a very rare case of a symptomatic adult patient with PAS and a coexisting tracheal anomaly with complete tracheal rings, referred to as a ‘ring-sling complex’.","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139303007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JRSM OpenPub Date : 2023-10-19eCollection Date: 2023-10-01DOI: 10.1177/20542704231205385
Gati Dawda, Andrew D Weeks, Susan Bewley
{"title":"'It must be right, I saw it on TV!': An observational study of third stage birth practices in popular television programmes.","authors":"Gati Dawda, Andrew D Weeks, Susan Bewley","doi":"10.1177/20542704231205385","DOIUrl":"10.1177/20542704231205385","url":null,"abstract":"<p><strong>Objectives: </strong>To examine modern media depictions of the third stage of birth in a selection of UK television representations.</p><p><strong>Design: </strong>Observational study of a sample of televised fictional and real births, audited against current National Institute of Health and Social Care Excellence (NICE) guidance.</p><p><strong>Setting: </strong>UK television channels BBC (<i>Call The Midwife</i> and <i>This Is Going To Hurt</i>) and Channel 4 (<i>One Born Every Minute</i>).</p><p><strong>Participants: </strong>87 births from 48 episodes, sampled from the three shows.</p><p><strong>Main outcome measures: </strong>The primary outcome was the number of births where the cord was clamped at more than 1 min after birth. Secondary outcomes included place and type of birth, measures of dignity and paternal involvement.</p><p><strong>Results: </strong>Overall, the timing of cord clamping was clearly shown in 25/87 (29%) of births, of which only 4/25 (16%) occurred at more than 1 min in screen time. The place of birth and caesarean section (CS) rate changed according to the series perspective and era; graphic explicit images were shown, but these related to CS detail.</p><p><strong>Conclusions: </strong>UK television shows have accurately depicted changes in place, culture and type of birth over the last century. They provide the public with a view of new rituals but an inaccurate picture of good quality care. Early cord clamping was shown in most births, even those set after 2014. No programme informed viewers about the safety aspects. When showing outdated practices, broadcasters have a public health duty to inform viewers that this is no longer recommended.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"14 10","pages":"20542704231205385"},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3d/ca/10.1177_20542704231205385.PMC10588410.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49691260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JRSM OpenPub Date : 2023-10-09eCollection Date: 2023-10-01DOI: 10.1177/20542704231200395
Sabrina Grant, Thomas Skinner, Deborah Turner, Gareth Griggs, Heather Eve
{"title":"An atypical case of progressive multifocal leukoencephalopathy in a patient with high grade B-cell lymphoma causing diagnostic delay.","authors":"Sabrina Grant, Thomas Skinner, Deborah Turner, Gareth Griggs, Heather Eve","doi":"10.1177/20542704231200395","DOIUrl":"10.1177/20542704231200395","url":null,"abstract":"<p><p>Progressive multifocal leukoencephalopathy (PML) is a rare disease of the central nervous system caused by opportunistic infection with JC virus. It presents in patients who are immunocompromised, and diagnosis is made by correlating clinical findings and radiological changes with the detection of JC virus in cerebrospinal fluid. Rarely, a brain biopsy is needed. A 72 year old with high grade B-cell lymphoma developed right arm weakness and limb ataxia shortly after his diagnosis. CNS involvement was excluded with a normal CT head, MRI brain/spine, and CSF examination. A paraneoplastic cause was suspected, and he received 5 cycles of Rituximab-containing chemotherapy to a complete metabolic remission. His neurology evolved during treatment despite serial MRI and CSF examination remaining normal. CSF and serum were both negative for JC virus by PCR. Following completion of chemotherapy, he deteriorated acutely with seizures and personality changes. It was only at this point that a repeat MRI showed new multiple scattered ring enhancing lesions within both cerebral hemispheres. The patient underwent a brain biopsy confirming JC virus positive-PML by immunohistochemistry and passed away one month later. This case illustrates the diagnostic challenges associated with PML and had several atypical features which led to diagnostic delay, specifically the onset of symptoms before starting immunochemotherapy, and the lack of radiological change despite evolving neurology. The eventual MRI abnormalities were not altogether classical for PML which, coupled with the JC-negativity in CSF and serum, meant a brain biopsy was required to reach the diagnosis.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"14 10","pages":"20542704231200395"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/80/8c/10.1177_20542704231200395.PMC10563469.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41204333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JRSM OpenPub Date : 2023-09-01DOI: 10.1177/20542704231197594
R Lyus, C Buamah, A M Pollock, L Cosgrove, P Brhlikova
{"title":"Global Burden of Disease 2017 estimates for Major Depressive Disorder: a critical appraisal of the epidemiological evidence.","authors":"R Lyus, C Buamah, A M Pollock, L Cosgrove, P Brhlikova","doi":"10.1177/20542704231197594","DOIUrl":"https://doi.org/10.1177/20542704231197594","url":null,"abstract":"<p><strong>Objectives: </strong>To critically appraise the quality of the studies underpinning the Global Burden of Disease (GBD) 2017 estimates for Major Depressive Disorder (MDD) with respect to i) the GBD 2017 inclusion criteria and ii) population coverage.</p><p><strong>Design: </strong>Systematic critical appraisal.</p><p><strong>Setting: </strong>Not applicable.</p><p><strong>Participants: </strong>Not applicable.</p><p><strong>Main outcome measures: </strong>Each study was critically appraised with respect to the four GBD 2017 inclusion criteria: representativeness, study method and sample, diagnostic criteria and publication from 1980 onwards. Population coverage was calculated.</p><p><strong>Results: </strong>Less than half of studies (221/467, 47.3%) were nationally representative. Only 262/467 (56.1%) of studies reported specifically on MDD and more than a third did not use DSM or ICD diagnostic criteria: 94/467 (20.1%) did not specify any diagnostic criteria and 68/467 (14.6%) relied on self-reported depression for diagnosis. Only 62/467 (13.3%) of studies were conducted during the period 2011-2017. Only 107/195 (54.9%) of countries had one or more prevalence studies.</p><p><strong>Conclusions: </strong>GBD 2017 estimates for MDD are based on incomplete country and population coverage. The inclusion of studies with non-representative populations, that do not use diagnostic criteria and the lack of specific data on MDD reduces the reliability of estimates and limits their value for policy making.</p>","PeriodicalId":17674,"journal":{"name":"JRSM Open","volume":"14 9","pages":"20542704231197594"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/86/8b/10.1177_20542704231197594.PMC10501079.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}