Ashok Sharma, Rajan Sharma, S. Aggarwal, V. Nirankari
{"title":"Gamma-irradiated corneas for therapeutic penetrating keratoplasty, anterior lamellar keratoplasty, and sclera for glaucoma valve surgery","authors":"Ashok Sharma, Rajan Sharma, S. Aggarwal, V. Nirankari","doi":"10.25259/ihopejo_12_2023","DOIUrl":"https://doi.org/10.25259/ihopejo_12_2023","url":null,"abstract":"\u0000\u0000To report clinical outcomes of gamma-irradiated donor cornea (GIDC) for therapeutic penetrating keratoplasty (TPK), deep anterior lamellar keratoplasty (DALK) and gamma-irradiated donor sclera (GIDS) for glaucoma patch graft (GPG) in glaucoma filtering surgery (GFS) with Ahmed glaucoma valve (AGV).\u0000\u0000\u0000\u0000A prospective non-randomized, non-comparative, interventional case series of GIDC and GIDS involving 26 patients, of which 20 received GIDC (11 TPK, 9 DALK) and 6 GIDS (6 GPG). Main outcome measures were post-operative tissue characteristics as epithelialization and tissue clarity; and complications including rejection, infection, corneal melt, and other adverse effects.\u0000\u0000\u0000\u0000Study included 26 patients, of these 20 received GIDC (11 TPK, 9 DALK) and 6 GIDS (6 GPG). Mean follow up was 8.32 ± 2.31 months. Corneal epithelium healed in 6.2 ± 2.58 days. Graft clarity was achieved in 9 (100%) DALK patients. Only 1 eye (3.8%) had a corneal melt. There were no incidences of rejection or infection in the follow up time.\u0000\u0000\u0000\u0000Gamma-irradiated sterilization of donor cornea and sclera is a new innovation to enhance utilization of donor tissue. GIDC is a promising treatment option for TPK and DALK; GIDS for GPG with good epithelialization time and tissue clarity. Gamma irradiation of both donor cornea and sclera achieved adequate sterilization and provided a long shelf life.\u0000","PeriodicalId":176313,"journal":{"name":"IHOPE Journal of Ophthalmology","volume":"38 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138588894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does dropout happen even with patients fitted with contact lenses for irregular cornea?","authors":"Sona Paul","doi":"10.25259/ihopejo_6_2023","DOIUrl":"https://doi.org/10.25259/ihopejo_6_2023","url":null,"abstract":"Objectives: Different types of contact lenses play a primary role in improving visual acuity in irregular corneas. Although there are multiple evidences for vision improvement with contact lens patients still drop out of lens wear and choose other methods of treatment, surgeries, or discontinue the lenses. Materials and Methods: Three thousand two hundred patients who were evaluated for 5 years at a specialty contact lens clinic in a tertiary eye care center, but did not return to the clinic for over 18 months from the date of dispensing were identified as dropouts. Only 73 patients were identified as falling under this category of dropout. The reasons for dropout were categorized as comfort-related, vision-related, other reasons, and those who underwent surgical procedures. Results: Unlike previous studies, which included soft lenses, this study revealed only 2.28% (73/3200) of dropouts. There were 38 patients with unilateral lens fitting and 35 patients with bilateral lens fitting. The visual acuity was significantly improving with contact lens in these eyes. The clinical presentation of these patients was analyzed to know about their stage of disease while they dropout from the contact lens clinic. Conclusion: Although dropout of contact lens is much lesser in irregular corneal conditions, it is important for the practitioner to be updated with the alternate and latest modality of lens choices to satisfy vision-related and comfort-related issues of patients.","PeriodicalId":176313,"journal":{"name":"IHOPE Journal of Ophthalmology","volume":"75 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135884386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Direct healthcare cost and barriers to the medical management of primary open-angle glaucoma in healthcare facilities in Yaounde – Cameroon","authors":"Christelle Domngang, Paola Maguib, Chantal Nanfack Ngoune, Yimta Foutse, Giles Kagmeni","doi":"10.25259/ihopejo_16_2023","DOIUrl":"https://doi.org/10.25259/ihopejo_16_2023","url":null,"abstract":"Objectives: The objective of this study was to estimate the direct healthcare cost of glaucoma among patients attending two healthcare services in Yaounde, Cameroon. Materials and Methods: This investigation was a hospital-based, observational, and cross-sectional study of 122 glaucoma patients on follow-up from January to August 2021. The study was carried out using a pre-tested questionnaire and analyzed sociodemographic and clinical characteristics, monthly income, investigations performed, medications prescribed, and direct healthcare costs. Data were analyzed using the Statistical Package for the Social Sciences version 24. Results: A total of 122 glaucoma follow-up patients participated in the study of whom 73 (59.9%) were male (sex ratio M/F = 1.49). Seventy-one (58.19%) participants were above 60 years. The majority (67.4%) had a higher education level. Over 40% of participants reported a monthly income of <228 Euros. Only 38 (31.1%) had health insurance. During the study year, each patient underwent 2.25 ± 0.84 consultations, 2.76 ± 1.40 ocular pressure measurements, 0.73 ± 0.52 visual field examinations, and 0.32 ± 0.2 gonioscopy. Prostaglandin analogs were the most widely prescribed drugs (71%), followed by β-blockers (Carteolol and Timolol) and carbonic anhydrase inhibitors with frequencies of 62% and 15%, respectively. The direct medical cost of the study population was estimated at 468.47 ± 155.34 Euros. The greatest proportion of out-of-pocket expenses (61.13% of medical costs) concerned the purchase of drugs, with an average cost of 284.16 ± 115.25 Euros. Patients treated in the public sector spent an average of 425.78 ± 38.49 Euros, while those treated in the private sector spent 562.22 ± 139.18 Euros during the study year ( P = 0.001). However, health coverage and type of glaucoma did not influence the direct cost of treatment. The main obstacles to glaucoma care were insufficient income followed by forgetfulness. Conclusion: The present study shows that almost all participants self-funded their glaucoma management. More than 60% of the direct healthcare cost was devoted to anti-glaucoma drugs and the main barrier to optimal glaucoma care was the lack of financial resources. All stakeholders need involvement, especially health policymakers, to prioritize glaucoma management to make it affordable for patients.","PeriodicalId":176313,"journal":{"name":"IHOPE Journal of Ophthalmology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135823592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge exchange seminar series – Session 1: Recruiting a guideline committee","authors":"Raashi Raj, Anirudh Gaurang Gudlavalleti, Hugh McGuire, Pilar Pinilla Dominguez","doi":"10.25259/ihopejo_18_2023","DOIUrl":"https://doi.org/10.25259/ihopejo_18_2023","url":null,"abstract":"A second round of knowledge exchange seminar series was organised as a part of the collaborative project between NICE International and IHOPE to develop and implement evidence-based clinical guidelines in India. The key ideas covered during this knowledge exchange included: Developing a recruitment policy to ensure consistency across guidelines. Developing a declaration of interest policy to ensure transparency in decision-making. Recruiting a variety of members (including patients or carers) with the required content expertise and experience to contribute to discussions on the guideline topic. Recruiting a chair who has experience in committee facilitation is likely to be broadly accepted by all in the committee and can guide and lead them through the guideline development process. This seminar outlined best practices in recruiting a committee, including the chair, for guideline development purposes. It is important to identify the expertise and experience needed for the committee early in the process.","PeriodicalId":176313,"journal":{"name":"IHOPE Journal of Ophthalmology","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135884564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ocular blood flow in normal tension glaucoma and primary open angle glaucoma","authors":"Shimpa Kundan, Rachel Joseph, Jyoti Shetty, Sheetal Ballal","doi":"10.25259/ihopejo_13_2023","DOIUrl":"https://doi.org/10.25259/ihopejo_13_2023","url":null,"abstract":"Objectives: The purpose of the study was to study the ocular blood flow (OBF) in primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG) by color Doppler imaging (CDI) in the ophthalmic artery (OA), central retinal artery (CRA), and posterior ciliary artery (PCA) and to correlate this with structural and functional damage in glaucoma. Materials and Methods: This was a cross-sectional and observational study. This was a cross-sectional study, in which 30 eyes of each group and controls were studied, CDI was done by a single observer for all cases. Peak systolic velocity (PSV), end-diastolic velocity (EDV), and resistive index (RI) were calculated for OA, CRA, and PCA. Visual fields and retinal nerve fiber layer (RNFL) analysis were done. Results: PSVs and EDVs were lower and RIs were higher for CRA and PCA of NTG and POAG compared to those of controls. The severity of glaucoma (visual field defect) increased when RI of OA was increased in NTG. No such relationship was established between RNFL thinning and OBF. Conclusion: Reduction in PSV and EDV leads to increased RI which is one of the contributory factors in the functional damage in NTG.","PeriodicalId":176313,"journal":{"name":"IHOPE Journal of Ophthalmology","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135883064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The pattern of ocular disorders in eye patient attendants in tertiary eye care centers","authors":"Aiman Khan, Mahendra Singh","doi":"10.25259/ihopejo_10_2023","DOIUrl":"https://doi.org/10.25259/ihopejo_10_2023","url":null,"abstract":"Objectives: This study aims to assess the pattern of ocular disorders in patient attendants at tertiary eye care centers. Materials and Methods: A cross-sectional study has been conducted at a tertiary eye care center in northern India. The study participants were adults aged 18 years who came along with patients. The study duration was from September 2022 to March 2022. This study was conducted to assess the ocular disorder inpatient attendant. The survey methods included the Bruckner test and torchlight examination. Results: A total of 202 subjects were assessed in our study. Of them, 71 (35.1%) were diagnosed with emmetropia. Refractive errors for distance were reported in 120 (59.4%) attendants. Of them, 104 (51.4%) did not have any previous eye disease, 81 (77.88%) were unaware, and 23 (22.11%) were aware of their ocular disorder. Conclusion: The majority of attendants who did not have any ocular symptoms and also never underwent any eye examination were suffering from eye disease. We found that there was a high significance between attendant ocular symptoms (without previous examination) and awareness ( P = 0.05).","PeriodicalId":176313,"journal":{"name":"IHOPE Journal of Ophthalmology","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135884097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Refractive status seen amongst school pupils with vernal keratoconjunctivitis in Jos East Local Government Area of Plateau State, North - Central Nigeria","authors":"Panshak Elisha Tenmang, Alice Venyir Ramyil, Salome Zajeme Wabare, Nachafiya Kadala, Gondim Seyilnen Kopse, Patricia Delsat Wade","doi":"10.25259/ihopejo_15_2023","DOIUrl":"https://doi.org/10.25259/ihopejo_15_2023","url":null,"abstract":"Objectives: This study aims to determine the types of refractive errors commonly seen in patients with Vernal keratoconjunctivitis (VKC) among the pupils in the Jos East Local Government area of Plateau State, Nigeria. Materials and Methods: A school-based descriptive study using a multistage sampling technique was carried out for 4 months. The visual acuity of the pupils was checked using a non-illuminated Snellen’s chart at 6 m, assessing one eye at a time. Individuals with visual acuity worse than 6/12 had pinhole tests and refraction done. Statistical analysis was done using Statistical Package for the Social Sciences version 20 and frequencies, simple percentages, and Chi-square were used to compare proportions. Results: A total of 400 participants were seen during the study, out of which 84 participants had vernal keratoconjunctivitis. Of these, 51 (60.7%) had refractive errors. Astigmatism was the most common form of refractive error seen in our study 26 (31%), myopia was seen in 15 (17.9%) whereas hypermetropia was the least seen in 10(11.9%). Simple astigmatism was seen more in individuals with acute stage of VKC 9 (75.0%) whereas compound astigmatism was commonly seen in participants with chronic stage of VKC (42.9%). Conclusion: Astigmatism was the commonest form of refractive error seen in these patients and simple astigmatism was the commonest variant of astigmatism seen.","PeriodicalId":176313,"journal":{"name":"IHOPE Journal of Ophthalmology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135885173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anirudh Gaurang Gudlavalleti, Hugh McGuire, Mark Rasburn
{"title":"Knowledge exchange seminar series – session 4: Patient expert training","authors":"Anirudh Gaurang Gudlavalleti, Hugh McGuire, Mark Rasburn","doi":"10.25259/ihopejo_19_2023","DOIUrl":"https://doi.org/10.25259/ihopejo_19_2023","url":null,"abstract":"Introduction: A second knowledge exchange seminar series was organised as a part of the collaborative project between NICE International and Indian health outcomes, public health and economics research centre (IHOPE) to develop and implement evidence-based clinical guidelines in India. The training of patient experts as a part of the committee is an important step in any committee’s development. Aim: To describe how IHOPE plans to provide training to patient representatives on its guideline committees. Conclusion: Continuous feedback from patient experts improves their experience of working in guideline committees and helps keep the training provided to all patient experts relevant and current.","PeriodicalId":176313,"journal":{"name":"IHOPE Journal of Ophthalmology","volume":"28 1-4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135823775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ownership, privacy, and value of health-care data: Perspectives and future direction","authors":"A. Das, Madhu Viswanathan","doi":"10.25259/ihopejo_33_2022","DOIUrl":"https://doi.org/10.25259/ihopejo_33_2022","url":null,"abstract":"In this ever expanding explosion of data in the world, we are at a crucial juncture to balance quality and quantity. In healthcare, there is a need to analyze voluminous datasets for the benefit of the patients while respecting their privacy and ownership. There is a need to understand the fundamental framework of co-creation of the data between the health-care provider and the patient. There is no more opportune time such as this to harness the potential of large datasets in healthcare to catalyze value-based care for the population.","PeriodicalId":176313,"journal":{"name":"IHOPE Journal of Ophthalmology","volume":"183 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123398248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Kumaran, D. Vedapriya, A. Manoharan, A. Nirupama
{"title":"Indian diabetic risk score screening of rural adults in Tamil Nadu","authors":"K. Kumaran, D. Vedapriya, A. Manoharan, A. Nirupama","doi":"10.25259/ihopejo_2_2023","DOIUrl":"https://doi.org/10.25259/ihopejo_2_2023","url":null,"abstract":"\u0000\u0000Diabetes is acknowledged as a key public health problem with the prevalence rate increasing globally and reaching epidemic proportions. It is high time that screening programs are implemented at the community level for early detection of the population, who are at risk of having diabetes mellitus.\u0000\u0000\u0000\u0000A community-based and cross-sectional study was conducted in the rural field practice area of a tertiary care hospital in Chengalpattu district, Tamil Nadu. The screening tool used to assess the risk status was the Indian diabetes risk score (IDRS) and the body mass index (BMI) of the participants was also calculated.\u0000\u0000\u0000\u0000A total of 396 formed the study population with the males constituting 47.2% of the study population. The majority were more than 50 years of age. Evaluating the risk status of study subjects using IDRS, the higher IDRS risk score was seen in 48.2% of participants, 47.2% had moderate risk, while only 3.5% had low risk. About 54.2% (n = 198) of participants were found to have a BMI within the normal range, 18.4% were underweight, 20.5% were overweight, and obesity was seen in 6.8% of the participants. A statistically significant association was found between gender and IDRS risk status, whereas no significant association was found between BMI category and IDRS risk status.\u0000\u0000\u0000\u0000Almost half of the study participants belonged to the high-risk category using IDRS screening. For the mass screening of diabetes, IDRS seems practically feasible and acceptable.\u0000","PeriodicalId":176313,"journal":{"name":"IHOPE Journal of Ophthalmology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127970815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}