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Journal of the Nippon Hospital Pharmacists Association最新文献

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Usage and Evaluation of a Program to Produce Drug Compliance Instruction-Sheets, MacAdvice 药品遵从性说明书程序的使用和评估
Journal of the Nippon Hospital Pharmacists Association Pub Date : 1997-08-10 DOI: 10.5649/JJPHCS1975.23.364
Hitoshi Sato, T. Yamanouchi, F. Kobayashi, Satomi Sato, I. Horikoshi
{"title":"Usage and Evaluation of a Program to Produce Drug Compliance Instruction-Sheets, MacAdvice","authors":"Hitoshi Sato, T. Yamanouchi, F. Kobayashi, Satomi Sato, I. Horikoshi","doi":"10.5649/JJPHCS1975.23.364","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.23.364","url":null,"abstract":"","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"30 1","pages":"364-374"},"PeriodicalIF":0.0,"publicationDate":"1997-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78397295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Determination of the Povidone-Iodine Contents by High-performance Liquid Chromatography 高效液相色谱法测定聚维酮碘含量
Journal of the Nippon Hospital Pharmacists Association Pub Date : 1997-06-10 DOI: 10.5649/JJPHCS1975.23.202
S. Ohshiro, N. Hokama, N. Hobara
{"title":"Determination of the Povidone-Iodine Contents by High-performance Liquid Chromatography","authors":"S. Ohshiro, N. Hokama, N. Hobara","doi":"10.5649/JJPHCS1975.23.202","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.23.202","url":null,"abstract":"The povidone-iodine contents in liquid and ointment were determined using high-performance liquid chromatography (HPLC). The chromatograph equipped reversed phase ODS column and detector was set at 355 nm. The flow rate of the mobile phase of methanol: water (7: 3) containing 1% KI was 1.0ml/min.The retention time of povidone-iodine was 3.9 min. When this HPLC was applied to the povidone-iodine preparations (gurgle and solution) on the commercial market, the povidoneiodinecontents were found to comprise more than 95%. In the povidone-iodine sugar ointment, which was prepared in the hospital pharmacy, admixed with lysozyme chloride ointment, the iodine contents by this HPLC had a good correlation with the available iodine contents by titration (r=0.9999). Furthermore, this method could also be applied to povidoneiodine in the organic solution after extracting the povidone-iodine sugar ointment admixed with lysozyme chloride ointment.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"13 1","pages":"202-206"},"PeriodicalIF":0.0,"publicationDate":"1997-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78833270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
保存剤を含有していない0.125%チロキサポール吸入液における一回量包装の有用性 不含防腐剂的0.125%酪氨酸酰吸入液中一次量包装的有效性
Journal of the Nippon Hospital Pharmacists Association Pub Date : 1997-06-10 DOI: 10.5649/jjphcs1975.23.225
一覚 杉山, 淳一 高橋, 井手上 寿美佳, 幸恵 金子, 富夫 松本, 守 建部
{"title":"保存剤を含有していない0.125%チロキサポール吸入液における一回量包装の有用性","authors":"一覚 杉山, 淳一 高橋, 井手上 寿美佳, 幸恵 金子, 富夫 松本, 守 建部","doi":"10.5649/jjphcs1975.23.225","DOIUrl":"https://doi.org/10.5649/jjphcs1975.23.225","url":null,"abstract":"By comparing the usual method of measuring medication dosage in medical cups in our hospital (A packages) with newly developed one dose packages (B, C packages) the stability of the ingredients, the sterility of the material, and the accuracy of the correctness of the measuring the samples, we assessed the usefulness of one dose packages of preservativefree 0.125% tyloxapol solutions for the administration of oral medications. The results were as follows: 1) pH tended to rise in A as the strage temperature increased but was stable in both B and C. No changes in the external appearance were detectable in any of them. 2) No microbial contamination was found in any of the packages, A, B or C. 3) The measuring accuracy was better in B and C than in A. Thus, the one dose packages appeared to be more useful than the usual method of measuring drugs using medical cups as a method by which 0.125% tyloxapol solutions for inhalations can be used safely and conveniently even when supplied to patients.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"44 1","pages":"225-230"},"PeriodicalIF":0.0,"publicationDate":"1997-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80251038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
球形吸着炭 (クレメジン原体) の吸着特性に関する検討 球形吸附炭(克雷梅津原体)的吸附特性研究
Journal of the Nippon Hospital Pharmacists Association Pub Date : 1997-06-10 DOI: 10.5649/JJPHCS1975.23.219
義輝 本田, 眞汎 中野
{"title":"球形吸着炭 (クレメジン原体) の吸着特性に関する検討","authors":"義輝 本田, 眞汎 中野","doi":"10.5649/JJPHCS1975.23.219","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.23.219","url":null,"abstract":"The adsorption characteristics of various adsorbates by spherical charcoal (Kremezin ®) were studied in vitro and then compared with those of powdered medical charcoal. Medical charcoal adsorbs substances with molecular weights ranging from several hundred daltons to several thousand daltons. Kremezin, however, adsorbs only low molecular weight substances with molecular weights of up to several hundred daltons. Therefore, the adsorption selectivity of Kremezin, which is related to the molecular weight of adsorbate, seemed to contribute to the specific pharmacological action of this drug under clinical conditions. In batch adsorption tests for various amines, amino acids and organic acids with molecular weightsof from 45 to 251, both adsorbents showed similar behaviors. An increase in the size of the adsorbate molecule enhanced the degree of adsorption, especially in compounds that are analogs. The molecular structure also seemed to be an important factor in the adsorption phenomena; an aromatic ring tended to increase the adsobability while the amino group, carboxyl group and hydroxyl group all showed a decrease in adsorbability.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"43 1","pages":"219-224"},"PeriodicalIF":0.0,"publicationDate":"1997-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79080772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
医薬品データベースよりDesk Top Publishing (DTP) を指向した院内医薬品集の試み (2) 以“Desk Top Publishing”(DTP)为导向的医疗药品集的尝试(2)
Journal of the Nippon Hospital Pharmacists Association Pub Date : 1997-04-10 DOI: 10.5649/JJPHCS1975.23.175
喜紀 寒河江, 昭子 富野, 敏夫 鈴木, 真治 桑原, 多 楠木
{"title":"医薬品データベースよりDesk Top Publishing (DTP) を指向した院内医薬品集の試み (2)","authors":"喜紀 寒河江, 昭子 富野, 敏夫 鈴木, 真治 桑原, 多 楠木","doi":"10.5649/JJPHCS1975.23.175","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.23.175","url":null,"abstract":"A hospital formulary designed for desk top publising (DTP) was published according to the online database system UMIN. In addition to the revision of the textual content, some illustrations and drawings were also inserted in the previous format of our formulary and the publication of the DTP-directed formulary was established in this edition. The database according to this new system at our hospital which has been maintained using a relational database software, was found to be useful for developing additional materials, such as worksheets as well as for insertings structural drawing objects on the drug tables each time. Using the local network system (LAN) by the Windows NT Server, it was possible to perform benefitial data conversions between different OS which thus led to the effective edition of our work. Electric publication of the formurary is suggested to be an excellent method provide the most up-to-date contents of all drug information and to satisfy the need to constantly update the informationl contents.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"237 1","pages":"175-184"},"PeriodicalIF":0.0,"publicationDate":"1997-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89072659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma Concentrations of Clonazepam Therapy in Epileptic Children 氯硝西泮治疗癫痫儿童的血药浓度
Journal of the Nippon Hospital Pharmacists Association Pub Date : 1997-02-10 DOI: 10.5649/JJPHCS1975.23.36
N. Morikawa, K. Ikawa, Taturo Izumi, M. Takeyama
{"title":"Plasma Concentrations of Clonazepam Therapy in Epileptic Children","authors":"N. Morikawa, K. Ikawa, Taturo Izumi, M. Takeyama","doi":"10.5649/JJPHCS1975.23.36","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.23.36","url":null,"abstract":"We discuss the correlation between plasma concentration and clinical dose of Clonazepam (CZP) combined with other anticonvulsants in epileptic children. The plasma concentrations were measured in 610 samples from 141 children (73 males and 68 females) by HPLC method. We found that the clinical doses of CZP in our hospital were lower than those directed in “Goodman and Gilman's The Pharmacological Basis of Therapeutics” and in “United States Pharmacopoeia Dispensing Information”, and that therefore the plasma concentrations were distributed at the low range correspondingly with doses. A correlation between plasma concentration and clinical doses of CZP was observed and the relationship depended on sex and age of the patients. The plasma concentration of CZP in the older group (over 11 years old) was higher than that in the younger group (from 0 to 10 years old) and that in the male group was higher than that in the female group.We surveyed the relationship between the plasma concentration and dose of CZP in two patients over the longterm. The results indicated the necessity for frequent therapeutic drug monitoring of CZP over the longterm at the changes of dose and patient weight.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"21 1","pages":"36-42"},"PeriodicalIF":0.0,"publicationDate":"1997-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90580878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
水溶性食物繊維より調製したプリロカイン-リドカイン含有ヒドロゲルパッチ (PLパッチ) の皮膚吸収性および有用性の評価 由水溶性膳食纤维制备的含有预罗卡因-利多卡因的氢凝胶贴片(PL贴片)的皮肤吸收性和有效性评估
Journal of the Nippon Hospital Pharmacists Association Pub Date : 1997-02-10 DOI: 10.5649/jjphcs1975.23.1
一則 渡邉, 秀 谷古宇, 順子 吉住, 敬之 原田, 幸三 高山, 恒司 永井
{"title":"水溶性食物繊維より調製したプリロカイン-リドカイン含有ヒドロゲルパッチ (PLパッチ) の皮膚吸収性および有用性の評価","authors":"一則 渡邉, 秀 谷古宇, 順子 吉住, 敬之 原田, 幸三 高山, 恒司 永井","doi":"10.5649/jjphcs1975.23.1","DOIUrl":"https://doi.org/10.5649/jjphcs1975.23.1","url":null,"abstract":"","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"24 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"1997-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80107473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preparation of Artificial Cerebrospinal Fluid Using Concentrated Electrolyte Injections. 浓缩电解质注射制备人工脑脊液的研究。
Journal of the Nippon Hospital Pharmacists Association Pub Date : 1996-06-10 DOI: 10.5649/JJPHCS1975.22.305
O. Fujishita, K. Kuroda, Y. Nakao, Y. Natori, M. Fukui, R. Oishi
{"title":"Preparation of Artificial Cerebrospinal Fluid Using Concentrated Electrolyte Injections.","authors":"O. Fujishita, K. Kuroda, Y. Nakao, Y. Natori, M. Fukui, R. Oishi","doi":"10.5649/JJPHCS1975.22.305","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.22.305","url":null,"abstract":"Two concentrated electrolyte injections (solution A and B) were used for the rapid and easy preparation of artificial cerebrospinal fluid (ACF). Solution A (10 ml) included Na, K, Mg, Ca, Cl, lactate, and glucose while solution B (20 ml) was composed of KH2 PO4 and NaHCO3. Solution A was first added to 0, 9% NaCl in jection (515 ml) maintained in a soft plastic bag followed by solution B. Notably, the prepared ACF had particulate matter counts far less than the Japanese pharmacopoeia (JP) and United States Pharmacopeia (USP) limits for large volume injections. Application of the present ACF to patients using a ventricular fiberscope caused no significant adverse effects, such as convulsion, headaches or fever.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"82 1","pages":"305-309"},"PeriodicalIF":0.0,"publicationDate":"1996-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77131309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of Efficacy of Prescription for Rational Use of Medication : Patient Consultation with "Prescription Card" 合理用药处方疗效评价:患者对“处方卡”的咨询
Journal of the Nippon Hospital Pharmacists Association Pub Date : 1996-06-10 DOI: 10.5649/JJPHCS1975.22.265
Ayana Suzuki, Naoko Mizogami, T. Orii, Hideyuki Shimizu, T. Seino, Y. Yamamura, Kouichi Nakamura, Y. Sawada, T. Iga
{"title":"Evaluation of Efficacy of Prescription for Rational Use of Medication : Patient Consultation with \"Prescription Card\"","authors":"Ayana Suzuki, Naoko Mizogami, T. Orii, Hideyuki Shimizu, T. Seino, Y. Yamamura, Kouichi Nakamura, Y. Sawada, T. Iga","doi":"10.5649/JJPHCS1975.22.265","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.22.265","url":null,"abstract":"","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"25 1","pages":"265-273"},"PeriodicalIF":0.0,"publicationDate":"1996-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81892131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmaceutical Evaluation for 10% Phenytoin Powders 10%苯妥英粉末的药学评价
Journal of the Nippon Hospital Pharmacists Association Pub Date : 1996-04-10 DOI: 10.5649/JJPHCS1975.22.149
Y. Kagawa, K. Sasaki, M. Matsushima, S. Inagaki, Michio Kojima
{"title":"Pharmaceutical Evaluation for 10% Phenytoin Powders","authors":"Y. Kagawa, K. Sasaki, M. Matsushima, S. Inagaki, Michio Kojima","doi":"10.5649/JJPHCS1975.22.149","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.22.149","url":null,"abstract":"A dispensing test of 10% phenytoin powders (10% DPH), which has the same bioavailability as the tablet, was investigated. Pharmaceutical characteristics including an apparent density, a dispersibility, grouping properties and an angle of repose of 10% DPH passed the criteria for dispensing from the hospital pharmacy. Next, according to clinical formulas, we designed the eight standard formulas that consisting 10% DPH with 10% phenobarbital powders, zonisamide powders, carbamazepine","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"17 1","pages":"149-158"},"PeriodicalIF":0.0,"publicationDate":"1996-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74432698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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