Journal of the Korean Society of Coloproctology最新文献

{"title":"Will the Stroma-derived Factor-1α (CXCL12)/CXCR4 Pathway Become a Major Concern for Advanced Colorectal Cancer?","authors":"Hungdai Kim","doi":"10.3393/jksc.2012.28.1.3","DOIUrl":"https://doi.org/10.3393/jksc.2012.28.1.3","url":null,"abstract":"See Article on Page 27-34 \u0000 \u0000The chemokine stroma-derived factor (SDF-1α/CXCL12) is a homeostatic chemokine. The major function of this chemokine is to regulate hematopoietic cell trafficking and secondary lymphoid tissue architecture [1]. SDF-1α is also widely expressed in various organs. Including the heart, liver, brain, kidney, skeletal muscle, and lymphoid organs, and it plays multiple roles in tumor pathogenesis. SDF-1α has been demonstrated to promote tumor growth, enhance tumor angiogenesis, participate in tumor metastasis, and contribute to immunosuppressive networks within the tumor microenvironment. SDF-1α expression is reported in ovarian cancer, breast cancer [2], colorectal cancer, pancreatic cancer, prostate cancer, thyroid cancer, and many other human tumors. \u0000 \u0000SDF-1α can increase the invasiveness and the migration of cancer cells, and its levels are correlated with node involvement and long-term survival in patients with breast cancer. SDF-1 may, therefore, have potential value in assessing clinical outcomes of patients with breast cancer [3]. Although colorectal cancer (CRC) tissues contain SDF-1α-positive stromal cells, immunohistochemistry clearly demonstrated that the cancerous cells in more than 50% of the CRC samples examined had much stronger expression of SDF-1α than their neighboring normal colonic epithelial cells. Accordingly, as with CXCR4 overexpression, the SDF-1α/CXCR4 pathway appears to play important roles in the progression of CRC [4]. \u0000 \u0000In this study, the authors merely measured the SDF-1α expression level in the normal colonic mucosa and in colorectal cancer tissue. If this study had included the SDF-1α specific receptor CXCR4 expression level, the authors would have obtained better results. Nevertheless, the results are quite impressive. SDF-1α expression was highly correlated with pericolic lymph-node metastasis, distant metastasis, tumor-node-metastasis stage and lymphovascular invasion. Strong SDF-1α expression was inversely related with patients' survival, suggesting suggest SDF-1α could be a prognostic factor. Further study evaluating the distinctive value of SDF-1α expression in clinical practice may be warranted. \u0000 \u0000According to the literature, it is evident that manipulation of this pathway represents a new strategy for cancer treatment. CXCR4 antagonists, such as Plerixafor (AMD3100) and T140 analogues (TN14003/BKT140), and blocking antibodies toward CXCR4 or SDF-1α are being investigated in various cancer settings. In an in vitro study using a colorectal cancer cell line, results indicate that a CXCR4-antagonistic therapy might prevent tumor cell dissemination and metastasis in CRC patients, consequently improving survival [5]. Of course, we need to bear in mind that although targeting CXCR4/CXCL12 is an attractive option in treating human tumors, it is certain that to gain effective, reliable, and consistent clinical efficacy, a definitive combinatorial therapeutic regimen should be found.","PeriodicalId":17346,"journal":{"name":"Journal of the Korean Society of Coloproctology","volume":"28 1","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/36/jksc-28-3.PMC3296939.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40158960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delorme's Procedure for Complete Rectal Prolapse: Does It Still Have It's Own Role?","authors":"Sooho Lee,&nbsp;Bong-Hyeon Kye,&nbsp;Hyung-Jin Kim,&nbsp;Hyeon-Min Cho,&nbsp;Jun-Gi Kim","doi":"10.3393/jksc.2012.28.1.13","DOIUrl":"https://doi.org/10.3393/jksc.2012.28.1.13","url":null,"abstract":"<p><strong>Purpose: </strong>Although there are more than a hundred techniques, including the transabdominal and the perineal approaches, for the repair of the rectal prolapsed, none of them is perfect. The best repair should be chosen not only to correct the prolapse but also to restore defecatory function and to improve fecal incontinence throughout the patient's lifetime. The aim of this retrospective review is to evaluate clinical outcomes of the Delorme's procedure for the management of the complete rectal prolapse.</p><p><strong>Methods: </strong>A total of 19 patients (13 females and 6 males) with complete rectal prolapses were treated by using the Delorme's procedure in St. Vincent's Hospital, The Catholic University of Korea, from February 1997 to February 2007. Postoperative anal incontinence was evaluated using the Cleveland Clinic Incontinence Score.</p><p><strong>Results: </strong>All 19 patients had incontinence to liquid stool, solid stool, and/or flatus preoperatively. Three (15.8%) patients reported recurrence of the rectal prolapse (at 6, 18, 29 months, respectively, after the operation). Information on postoperative incontinence was available for 16 of the 19 patients. Twelve of the 16 patients (75%) reported improved continence (5 [31.3%] were improved and 7 [43.7%] completely recovered from incontinence) while 4 patients had unchanged incontinence symptoms. One (6.3%) patient who did not have constipation preoperatively developed constipation after the operation.</p><p><strong>Conclusion: </strong>The Delorme's procedure is associated with a marked improvement in anal continence, relatively low recurrence rates, and low incidence of postoperative constipation. This allows us to conclude that this procedure still has its own role in selected patients.</p>","PeriodicalId":17346,"journal":{"name":"Journal of the Korean Society of Coloproctology","volume":"28 1","pages":"13-8"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fb/aa/jksc-28-13.PMC3296936.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40158964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multivariate Analysis of the Survival Rate for Treatment Modalities in Incurable Stage IV Colorectal Cancer.","authors":"Sung Kang Kim, Chang Ho Lee, Min Ro Lee, Jong Hun Kim","doi":"10.3393/jksc.2012.28.1.35","DOIUrl":"10.3393/jksc.2012.28.1.35","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to compare survival in patients that underwent palliative resection treatment versus non-resection for incurable colorectal cancer (ICRC).</p><p><strong>Methods: </strong>The case records of 201 patients with ICRC between January 2000 and December 2009 were reviewed. Demographics, American Society of Anesthesiologists (ASA) score, carcinoembryonic antigen (CEA) level, the location of the colon cancer, histology, metastasis, treatment options and median survival were analyzed retrospectively. We divided the patients into four groups according to the treatment modalities: resection alone, resection with post-operative chemotherapy, non-resection treatment by chemotherapy alone, and stent or bypass. Median survival times were compared according to each treatment option, and the survival rates were analyzed.</p><p><strong>Results: </strong>105 patients underwent palliative resection whereas 96 were treated with non-resection modalities. A palliative resection was performed in 44 cases for resection alone and in 61 cases for resection with post-operative chemotherapy. In patients treated with non-resection of the primary tumor, chemotherapy alone was done in 65 cases and stent or bypass in 31 cases. Multivariate analysis showed a median survival of 14 months in patients with palliative resections with post-operative chemotherapy, which was significantly higher than those for chemotherapy alone (8 months), primary tumor resection alone (5 months), and stent or bypass (5 months). Gender, age, ASA score, CEA level, the location of colon cancer, histology and the presence of multiple metastases were not independent factors in association with the median survival rate.</p><p><strong>Conclusion: </strong>In the treatment of ICRC, palliative resection followed by post-operative chemotherapy shows the most favorable median survival compared to other treatment options.</p>","PeriodicalId":17346,"journal":{"name":"Journal of the Korean Society of Coloproctology","volume":"28 1","pages":"35-41"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9a/08/jksc-28-35.PMC3296940.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40158967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New techniques for treating an anal fistula.","authors":"Kee Ho Song","doi":"10.3393/jksc.2012.28.1.7","DOIUrl":"10.3393/jksc.2012.28.1.7","url":null,"abstract":"<p><p>Surgery for an anal fistula may result in recurrence or impairment of continence. The ideal treatment for an anal fistula should be associated with low recurrence rates, minimal incontinence and good quality of life. Because of the risk of a change in continence with conventional techniques, sphincter-preserving techniques for the management complex anal fistulae have been evaluated. First, the anal fistula plug is made of lyophilized porcine intestinal submucosa. The anal fistula plug is expected to provide a collagen scaffold to promote tissue in growth and fistula healing. Another addition to the sphincter-preserving options is the ligation of intersphincteric fistula tract procedure. This technique is based on the concept of secure closure of the internal opening and concomitant removal of infected cryptoglandular tissue in the intersphincteric plane. Recently, cell therapy for an anal fistula has been described. Adipose-derived stem cells have two biologic properties, namely, ability to suppress inflammation and differentiation potential. These properties are useful for the regeneration or the repair of damaged tissues. This article discusses the rationales for, the estimated efficacies of, and the limitations of new sphincter-preserving techniques for the treatment of anal fistulae.</p>","PeriodicalId":17346,"journal":{"name":"Journal of the Korean Society of Coloproctology","volume":"28 1","pages":"7-12"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3393/jksc.2012.28.1.7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40158963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laparoscopic right hemicolectomy for colon cancer: technically feasible and safe to perform in terms of oncologic outcomes.","authors":"Moo Jun Baek","doi":"10.3393/jksc.2012.28.1.5","DOIUrl":"https://doi.org/10.3393/jksc.2012.28.1.5","url":null,"abstract":"See Article on Page 42-48 \u0000 \u0000It has already proved that laparoscopic surgery is not any less inferior to conventional open surgery in terms of its safety and efficacy to treat colon cancer [1, 2]. From this point of view, this study reviewed the outcomes of laparoscopic right hemicolectomy retrospectively as a treatment of colon cancer. The study was considered to be significant as the outcome of a single surgery although it was not the randomized prospective study with large scale of samples. In South Korea, the outcomes of laparoscopic surgery for colon cancer have been reported but they have not been extensive yet. Therefore, the outcomes of a single surgery such as laparoscopic right hemicolectomy performed by the author of this study are judged to be a good evidence to support the outcomes of laparoscopic surgeries. Nevertheless, this study had several flaws to demonstrate the advantages of laparoscopic right hemicolectomy perfectly comparing to conventional open right hemicolectomy. It is mainly because this study is not prospective study and there aren't control groups as well as the sample size was too small. However, data is collecting prospectively with a larger scale of sample and more solid evidence is expected to be produce with this data. In addition to this, if more surgeons are participated in researches expanding the range of subjects, more reliable evidence will be constructed.","PeriodicalId":17346,"journal":{"name":"Journal of the Korean Society of Coloproctology","volume":"28 1","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/10/1a/jksc-28-5.PMC3296943.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40158961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stromal-cell-derived Factor 1-α Promotes Tumor Progression in Colorectal Cancer.","authors":"Se Jun Park,&nbsp;Tae Sung Ahn,&nbsp;Sung Woo Cho,&nbsp;Chang Jin Kim,&nbsp;Dong Jun Jung,&nbsp;Myung Won Son,&nbsp;Sang Ho Bae,&nbsp;Eung Jin Shin,&nbsp;Moon Soo Lee,&nbsp;Chang Ho Kim,&nbsp;Moo Jun Baek","doi":"10.3393/jksc.2012.28.1.27","DOIUrl":"https://doi.org/10.3393/jksc.2012.28.1.27","url":null,"abstract":"<p><strong>Purpose: </strong>Although stromal-cell-derived factor (SDF)-1α is suggested to be involved in tumorigenicity and tumor angiogenesis, the clinicopathological significance of its expression in colorectal cancers is not fully understood. We examined SDF-1α expression in colorectal cancers and investigated its relationship to clinicopathological features such as tumor staging, lymph-node metastasis, vascular invasion (VI), lymphatic invasion (LI) and neural invasion (NI).</p><p><strong>Methods: </strong>Specimens of 83 primary colorectal cancers were examined immunohistochemically, and the relationships between clinicopathological features and SDF-1α expression were analyzed. To compare the expressions between the normal colon tissue and colorectal cancer tissues, we performed Western blot analyses.</p><p><strong>Results: </strong>According to the Western blot analyses, SDF-1α was more highly expressed in colorectal carcinoma tissues than in normal colonic mucosa (20/21). According to the immunohistochemical stain, SDF-1α was associated with nodal status, distant metastasis, tumor staging, VI and LI. SDF-1α expression had a significant prognostic value for overall survival. Kaplan-Meier plots of survival in patients with high SDF-1α showed that high SDF-1α expression was associated with a shorter overall survival. However, no association was found between SDF-1α expression and other pathologic or clinical variables, including age, gender, degree of differentiation, and presence of perineural invasion.</p><p><strong>Conclusion: </strong>The expression of SDF-1α might be associated with tumor progression in colorectal cancer. Inhibition of SDF-1α could be a therapeutic option in colorectal cancer patients.</p>","PeriodicalId":17346,"journal":{"name":"Journal of the Korean Society of Coloproctology","volume":"28 1","pages":"27-34"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1f/08/jksc-28-27.PMC3296938.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40158966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oncologic Outcomes of a Laparoscopic Right Hemicolectomy for Colon Cancer: Results of a 3-Year Follow-up.","authors":"Jung Hoon Cho, Dae Ro Lim, Hyuk Hur, Byung Soh Min, Seung Hyuk Baik, Kang Young Lee, Nam Kyu Kim","doi":"10.3393/jksc.2012.28.1.42","DOIUrl":"10.3393/jksc.2012.28.1.42","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study is to evaluate the oncologic outcomes of a laparoscopic-assisted right hemicolectomy for the treatment of colon cancer and compare the results with those of previous randomized trials.</p><p><strong>Methods: </strong>From June 2006, to December 2008, 156 consecutive patients who underwent a laparoscopic right hemicolectomy with a curative intent for colon cancer were evaluated. The clinicopatholgic outcomes and the oncologic outcomes were evaluated retrospectively by using electronic medical records.</p><p><strong>Results: </strong>There were 84 male patients and 72 female patients. The mean possible length of stay was 7.0 ± 1.5 days (range, 4 to 12 days). The conversion rate was 3.2%. The total number of complications was 30 (19.2%). Anastomotic leakage was not noted. There was no mortality within 30 days. The 3-year overall survival rate of all stages was 93.3%. The 3-year overall survival rates according to stages were 100% in stage I, 97.3% in stage II, and 84.8% in stage III. The 3-year disease-free survival rate of all stages was 86.1%. The 3-year disease-free survival rates according to stage were 96.2% in stage I, 90.3% in stage II, and 75.6% in stage III. The mean follow-up period was 36.3 (3 to 60) months.</p><p><strong>Conclusion: </strong>A laparoscopic right hemicolectomy for the treatment of colon cancer is technically feasible and safe to perform in terms of oncologic outcomes. The present data support previously reported randomized trials.</p>","PeriodicalId":17346,"journal":{"name":"Journal of the Korean Society of Coloproctology","volume":"28 1","pages":"42-8"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/80/51/jksc-28-42.PMC3296941.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40160106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Short-term Surgical Outcomes between a Robotic Colectomy and a Laparoscopic Colectomy during Early Experience.","authors":"Jin Yong Shin","doi":"10.3393/jksc.2012.28.1.19","DOIUrl":"https://doi.org/10.3393/jksc.2012.28.1.19","url":null,"abstract":"<p><strong>Purpose: </strong>Although robotic surgery was invented to overcome the technical limitations of laparoscopic surgery, the role of a robotic (procto)colectomy (RC) for the treatment of colorectal cancer compared to that of a laparoscopic (procto)colectomy (LC) was not well defined during the initial adoption periods of both procedures. This study aimed to evaluate the efficacy and the safety of a RC for the treatment of colorectal cancer by comparing the authors' initial experiences with both a RC and a LC.</p><p><strong>Methods: </strong>The first 30 patients treated by using a RC for colorectal cancer from July 2010 to March 2011 were compared with the first 30 patients treated by using a LC for colorectal cancer from December 2006 to June 2007 by the same surgeon. Perioperative variables and short-term outcomes were analyzed. In addition, the 30 RC and the 30 LC cases involved were divided into rectal cancer (n = 17 and n = 12, respectively), left-sided colon cancer (n = 7 and n = 12, respectively) and right-sided colon cancer (n = 6 and n = 6, respectively) for subgroup analyses.</p><p><strong>Results: </strong>The mean operating times for RC and LC were significantly different at 371.8 and 275.5 minutes, respectively, but other perioperative parameters (rates of open conversion, numbers of retrieved lymph node, estimated blood losses, times to first flatus, maximal pain scores before discharge and postoperative hospital stays) were not significantly different in the two groups. Subgroup analyses showed that the mean operative times for a robotic proctectomy and a laparoscopic proctectomy were 396.5 and 298.8 minutes, respectively (P < 0.000). Postoperative complications occurred in five patients in the RC group and in six patients in the LC group (P = 0.739).</p><p><strong>Conclusion: </strong>Although the short-term outcomes of a RC during its initial use were better than those of a LC (with the exception of operating time), differences were not found to be significantly different. On the other hand, the longer operation time of a robotic proctectomy compared to that of a laparoscopic proctectomy during the early period may be problematic.</p>","PeriodicalId":17346,"journal":{"name":"Journal of the Korean Society of Coloproctology","volume":"28 1","pages":"19-26"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7c/57/jksc-28-19.PMC3296937.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40158965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Operative treatment with a laparotomy for anorectal problems arising from a self-inserted foreign body.","authors":"Seung-Bum Ryoo,&nbsp;Heung-Kwon Oh,&nbsp;Heon-Kyun Ha,&nbsp;Eun Kyung Choe,&nbsp;Sang Hui Moon,&nbsp;Kyu Joo Park","doi":"10.3393/jksc.2012.28.1.56","DOIUrl":"https://doi.org/10.3393/jksc.2012.28.1.56","url":null,"abstract":"<p><p>An anorectal foreign body can cause serious complications such as incontinence, rectal perforation, peritonitis, or pelvic abscess, so it should be managed immediately. We experienced two cases of operative treatment for a self-inserted anorectal foreign body. In one, the foreign body could not be removed as it was completely impacted in the anal canal. We failed to remove it through the anus. A laparotomy and removal of the foreign body was performed by using an incision on the rectum. Primary colsure and a sigmoid loop colostomy were done. A colostomy take-down was done after three months. The other was a rectal perforation from anal masturbation with a plastic device. We performed primary repair of the perforated rectosigmoid colon, and we didea sigmoid loop colostom. A colostomy take-down was done three months later. Immediate and proper treatment for a self-inserted anorectal foreign body is important to prevent severe complications, and we report successful surgical treatments for problems caused by anorectal foreign bodies.</p>","PeriodicalId":17346,"journal":{"name":"Journal of the Korean Society of Coloproctology","volume":"28 1","pages":"56-60"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/38/7a/jksc-28-56.PMC3296944.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40160108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to treat retrorectal cysts or tumors in adult.","authors":"Bong Hwa Lee,&nbsp;Hyoung Chul Park,&nbsp;Byung Seup Kim","doi":"10.3393/jksc.2011.27.6.276","DOIUrl":"https://doi.org/10.3393/jksc.2011.27.6.276","url":null,"abstract":"See Article on Page 303-314 \u0000 \u0000Retrorectal or presacral tumors are rare and can be challenging to diagnose and treat. Because the retrorectal space contains multiple embryologic remnants derived from various tissues, the tumors that develop in this space are heterogeneous. Lesions are classified as congenital, neurogenic, osseous, inflammatory, or miscellaneous. The diagnosis is not difficult if one uses abdomenpelvis computed tomography and magnetic resonance imaging. The cases become difficult to treat when the patient has had a previous operation such as drainage of its content under the diagnosis of an anal fistula or sinus. Although treatment depends on diagnosis and anatomic location, most retrorectal lesions require surgical resection. Most lesions are benign, but malignant neoplasms are not uncommon. Thus, we should consider the bias in the article in terms of the retrorectal cyst being benign. When removal of the retrorectal mass is to be attempted, a frozen pathologic examination is mandatory. \u0000 \u0000Waldeyer's facia, which is a good landmark for surgery, divides the retrorectal space into inferior and superior compartments. There are no nerves, blood vessels or lymphatics within two leaves. \u0000 \u0000The operative approach is determined on digital examination and radiologic findings. When the examiner's finger cannot palpate the upper edge of the tumor, removing the cyst by only using a posterior approach is difficult. Levator muscles should be closed with sutures in cases of posterior approaches.","PeriodicalId":17346,"journal":{"name":"Journal of the Korean Society of Coloproctology","volume":"27 6","pages":"276"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/76/d8/jksc-27-276.PMC3259421.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30398886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}