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Propoxyphene. 丙氧芬。
Journal of the American Pharmaceutical Association Pub Date : 2020-02-07 DOI: 10.32388/uorgka
R. Poust, J. Jaffe
{"title":"Propoxyphene.","authors":"R. Poust, J. Jaffe","doi":"10.32388/uorgka","DOIUrl":"https://doi.org/10.32388/uorgka","url":null,"abstract":"T he d-isomer of synthetic diphenyl propionate derivative propoxyphene, with narcotic analgesic effect. T his agent mimics the effects of the endogenous opiate dextropropoxyphene, by binding to mu receptors located throughout the central nervous system. T he binding results in GT P to GDP exchanges on the mu-G-protein complex, by which effector adenylate cyclase is inactivated thereby decreasing intracellular cAMP. T his, in turn, inhibits the release of various nociceptive neurotransmitters, such as substance P, gamma-aminobutyric acid (GABA), dopamine, acetylcholine, noradrenaline, vasopressin, and somatostatin. In addition, dextropropoxyphene closes N-type voltagegated calcium channels and opens calcium-dependent inwardly rectifying potassium channels. T his results in hyperpolarization, thereby reducing neuronal excitability, which further decreases the perception of pain. Qeios · Definition, February 7, 2020","PeriodicalId":17212,"journal":{"name":"Journal of the American Pharmaceutical Association","volume":"20 1","pages":"97-100"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81296054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Sulfisoxazole. Sulfisoxazole。
Journal of the American Pharmaceutical Association Pub Date : 2020-02-07 DOI: 10.32388/o9oqqi
{"title":"Sulfisoxazole.","authors":"","doi":"10.32388/o9oqqi","DOIUrl":"https://doi.org/10.32388/o9oqqi","url":null,"abstract":"A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfisoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.","PeriodicalId":17212,"journal":{"name":"Journal of the American Pharmaceutical Association","volume":"58 1","pages":"617-20"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89493265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The “shaking‐out” method for the quantitative estimation of alkaloids. II. Effect of clarification and “salting‐out” 生物碱定量测定的“摇出法”。2澄清和“盐析”的效果
Journal of the American Pharmaceutical Association Pub Date : 2018-01-08 DOI: 10.1002/JPS.3080090104
G. Beal, T. S. Hamilton
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引用次数: 1
Drug interactions. 药物的相互作用。
Journal of the American Pharmaceutical Association Pub Date : 2015-05-01 DOI: 10.1542/9781581109276-drug
L. Block, P. Lamy
{"title":"Drug interactions.","authors":"L. Block, P. Lamy","doi":"10.1542/9781581109276-drug","DOIUrl":"https://doi.org/10.1542/9781581109276-drug","url":null,"abstract":"","PeriodicalId":17212,"journal":{"name":"Journal of the American Pharmaceutical Association","volume":"18 1","pages":"202-7"},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79183164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A common freshman year for all students entering professional colleges 对于所有进入专业学院的学生来说，这是一个普通的大一学年
Journal of the American Pharmaceutical Association Pub Date : 2009-05-06 DOI: 10.1002/JPS.3080110815
F. J. Wulling
{"title":"A common freshman year for all students entering professional colleges","authors":"F. J. Wulling","doi":"10.1002/JPS.3080110815","DOIUrl":"https://doi.org/10.1002/JPS.3080110815","url":null,"abstract":"","PeriodicalId":17212,"journal":{"name":"Journal of the American Pharmaceutical Association","volume":"147 1","pages":"626-627"},"PeriodicalIF":0.0,"publicationDate":"2009-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80615940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of diethylphthalate in whisky 威士忌中邻苯二甲酸二乙酯的检测
Journal of the American Pharmaceutical Association Pub Date : 2008-04-15 DOI: 10.1002/JPS.3080110407
A. Lyons
{"title":"Detection of diethylphthalate in whisky","authors":"A. Lyons","doi":"10.1002/JPS.3080110407","DOIUrl":"https://doi.org/10.1002/JPS.3080110407","url":null,"abstract":"","PeriodicalId":17212,"journal":{"name":"Journal of the American Pharmaceutical Association","volume":"60 1","pages":"262-265"},"PeriodicalIF":0.0,"publicationDate":"2008-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84903409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmazeutischer Kalender 1922. Herausgegeben von Ernst Urban. 62. Edition. In 2 parts. Berlin, Verlag von Julius Springer 1922年制药日历(尤金翻译:.版两步之内柏林斯普林格出版社
Journal of the American Pharmaceutical Association Pub Date : 2008-04-15 DOI: 10.1002/JPS.3080110424
Otto Raubenheimer
{"title":"Pharmazeutischer Kalender 1922. Herausgegeben von Ernst Urban. 62. Edition. In 2 parts. Berlin, Verlag von Julius Springer","authors":"Otto Raubenheimer","doi":"10.1002/JPS.3080110424","DOIUrl":"https://doi.org/10.1002/JPS.3080110424","url":null,"abstract":"","PeriodicalId":17212,"journal":{"name":"Journal of the American Pharmaceutical Association","volume":"28 1 1","pages":"319-319"},"PeriodicalIF":0.0,"publicationDate":"2008-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85185735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Soluble compound spirit of orange and a simplified process for aromatic elixir 可溶性复方橙精及芳香长生不老药的简化工艺
Journal of the American Pharmaceutical Association Pub Date : 2008-04-15 DOI: 10.1002/JPS.3080110411
Ernest Jones
{"title":"Soluble compound spirit of orange and a simplified process for aromatic elixir","authors":"Ernest Jones","doi":"10.1002/JPS.3080110411","DOIUrl":"https://doi.org/10.1002/JPS.3080110411","url":null,"abstract":"","PeriodicalId":17212,"journal":{"name":"Journal of the American Pharmaceutical Association","volume":"36 1","pages":"277-278"},"PeriodicalIF":0.0,"publicationDate":"2008-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79156798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dehydrated products in commerce and in the sciences 商业和科学领域的脱水产品
Journal of the American Pharmaceutical Association Pub Date : 2008-04-15 DOI: 10.1002/JPS.3080110205
L. Gershenfeld
{"title":"Dehydrated products in commerce and in the sciences","authors":"L. Gershenfeld","doi":"10.1002/JPS.3080110205","DOIUrl":"https://doi.org/10.1002/JPS.3080110205","url":null,"abstract":"","PeriodicalId":17212,"journal":{"name":"Journal of the American Pharmaceutical Association","volume":"32 1","pages":"86-90"},"PeriodicalIF":0.0,"publicationDate":"2008-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77241459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Manufacture of Synthetic Medicinal Chemicals in America 美国合成药物化学制品的生产
Journal of the American Pharmaceutical Association Pub Date : 2008-04-15 DOI: 10.1002/JPS.3080110209
Alfred S. Burdick
{"title":"The Manufacture of Synthetic Medicinal Chemicals in America","authors":"Alfred S. Burdick","doi":"10.1002/JPS.3080110209","DOIUrl":"https://doi.org/10.1002/JPS.3080110209","url":null,"abstract":"","PeriodicalId":17212,"journal":{"name":"Journal of the American Pharmaceutical Association","volume":"44 1","pages":"98-108"},"PeriodicalIF":0.0,"publicationDate":"2008-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85564695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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