{"title":"Long-Term Follow-Up of Patients with Brugada Syndrome: Foremost Risk Factors Associated with Arrhythmic Events","authors":"Camkiran Volkan, Ozden Ozge, Atar Ilyas","doi":"10.23937/2643-3966/1710060","DOIUrl":"https://doi.org/10.23937/2643-3966/1710060","url":null,"abstract":"Background: Brugada syndrome (BS) is characterized by ST segment elevation in right precordial leads (V1-3), ventricular tachycardia (VT), ventricular fibrillation (VF) and sudden cardiac death (SCD) in individuals without structural heart disease. The aim of this study was to assess parameters associated with in patients with BS. Methods: A total of 68 patients diagnosed with BS or had Brugada Type ECG Change (BTEC) between January 1997 and July 2012 at the Department of Cardiology of Başkent University Faculty of Medicine, Ankara, Turkey were included. Patients were screened every 6 months for arrhythmia-related syncope, SCD, appropriate and inappropriate defibrillation (shock), AF development and death; collectively defined as “arrhythmic events” and were the primary endpoints. Patients with and without arrhythmic events were compared. Results: The mean age was 34.9 ± 12.2 years (9-71 years), and 52 (76.5%) patients were male. Mean follow-up was 49.6 ± 37.6 months (4-188 months). Univariate analysis showed that male sex (p = 0.004), Type 1 electrocardiographic pattern (p = 0.008), SCD (p = 0.036), VT/VF history (p = 0.046), requirement for electrophysiological studies (p = 0.034), implantable cardioverter-defibrillator (ICD) placement (p = 0.014) was found to demonstrate significant differences in patients with and without arrhythmic events. In multivariable analyzes, spontaneous Type 1 ECG presence (HR = 8.54, 95% CI: 0.38-26.37; p = 0.003) and VT/VF history (HR = 9.21, 95% CI: 0.004-1.88; p = 0.002) were found to be independently associated with arrhythmic events. Conclusion: We found the presence of spontaneous type 1 ECG and a history of VT/VF to be associated with increased likelihood of arrhythmic events in BS. Comprehensive studies investigating factors that could be used for risk assessment are necessary.","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"122 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139132823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Medical and Day-to-Day Burden on Families of Children with Hypoplastic Left Heart Syndrome Who Have Undergone Single Ventricle Surgical Palliation over a Decade","authors":"Hanft Erin, Abascal Elena, Ferris Anne, Parravicini Elvira","doi":"10.23937/2643-3966/1710059","DOIUrl":"https://doi.org/10.23937/2643-3966/1710059","url":null,"abstract":"","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"1 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139135712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Sachini, Paudel Grish, Yadav Uday Narayan, I. Shariful, Rawal Lal
{"title":"Cardiovascular Diseases Risk Assessment among South and South-East Asian Migrants Living in Greater Sydney, Australia: A Cross-Sectional Study","authors":"W. Sachini, Paudel Grish, Yadav Uday Narayan, I. Shariful, Rawal Lal","doi":"10.23937/2643-3966/1710052","DOIUrl":"https://doi.org/10.23937/2643-3966/1710052","url":null,"abstract":"","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121831649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kapuku Gaston K, Brown Michelle L, Suzuki Shin, Coughlin Stephen
{"title":"Persistence of Stress Related Left Ventricular Filling Abnormality in Treated Hypertensive Patients","authors":"Kapuku Gaston K, Brown Michelle L, Suzuki Shin, Coughlin Stephen","doi":"10.23937/2643-3966/1710053","DOIUrl":"https://doi.org/10.23937/2643-3966/1710053","url":null,"abstract":"","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131102807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Zagarese, A. Varriale, G. Puntel, G. Pesarini, A. Cristofaletti, C. Sandrini, F. Ribichini, M. Prioli
{"title":"A Case Series: Long-Term Follow-Up of Four Patients with Kawasaki Disease who Developed Coronary Artery Disease","authors":"G. Zagarese, A. Varriale, G. Puntel, G. Pesarini, A. Cristofaletti, C. Sandrini, F. Ribichini, M. Prioli","doi":"10.23937/2643-3966/1710050","DOIUrl":"https://doi.org/10.23937/2643-3966/1710050","url":null,"abstract":"","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124497912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"External Multicenter Validation of the Mehran Risk Score for Contrast Induced Acute Kidney Injury","authors":"A. Nashwa","doi":"10.23937/2643-3966/1710048","DOIUrl":"https://doi.org/10.23937/2643-3966/1710048","url":null,"abstract":"Background: Contrast induced acute kidney injury (CIAKI) is a known complication of percutaneous coronary intervention (PCI). Mehran Risk Score (MR score) has been previously shown to predict CIAKI, renal replacement therapy (RRT), and one-year mortality in patients undergoing PCI. The purpose of our study was to externally validate the MR score. Methods: To examine the utility of the MR score we reviewed records of 931 adult patients who underwent PCI in 2005 at 3 academic medical centers. Patients with acute myocardial infarction, end stage renal disease and contrast exposure within one week of PCI were excluded. MR score was calculated for each patient and stratified into 4 groups: MR score 0-5 (group 1), 6-10 (group 2), 11-15 (group 3), ≥ 16 (group 4). CIAKI was defined as an increase in serum creatinine of 25% or 0.5 mg/dl over baseline 48 hours post PCI. Need for hemodialysis was assessed within 1 month after PCI. All-cause mortality was assessed 1 year after PCI. Likelihood ratio was calculated to assess the MR score discrimination for our data as well as Mehran, et al. Results: The overall incidence of CIAKI, hemodialysis and mortality were 12.2%, 0.4%, and 9.0% respectively. A higher MR score was strongly associated with development of CIAKI and mortality (p < 0.01 for trend). There was no difference in the rate of CIAKI overall or in each MR score group when the 2 populations were compared, however, the risk of death was higher in our population (RR 1.58, CI 1.371.89, p < 0.001). Conclusion: In conclusion, we were able to externally validate the MR score as a useful tool to predict CIAKI and one-year all-cause mortality post PCI.","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129879201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Khorsandi Michael, M. Nirmala, Ebrahimihoor Elnaz, Muganlinskaya Nargiz
{"title":"Surviving the Death Roll; Unveiling the Undiagnosed: Case of Hispanic Man with Covid-19 Pneumonia","authors":"Khorsandi Michael, M. Nirmala, Ebrahimihoor Elnaz, Muganlinskaya Nargiz","doi":"10.23937/2643-3966/1710044","DOIUrl":"https://doi.org/10.23937/2643-3966/1710044","url":null,"abstract":"Brugada syndrome (BrS) is an inherited electrophysiological abnormality which typically manifests in patients with diverse ethnicities as ventricular arrhythmias or sudden cardiac death. The onset is frequently unmasked by various precipitating factors including but not limited to febrile diseases. Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) infection and associated COVID-19 illness continues to evolve. We are reporting a severe case of Covid-19 infection unveiling the undiagnosed Brugada syndrome, and the complicated course requiring mechanical ventilation and rounds of Cardiopulmonary resuscitation. A 57-years-old Hispanic man with no known prior cardiac history presented to the emergency department with fever and altered mental status. Initial investigations revealed mild leukocytosis, and positive SARS-CoV-2 PCR. The patient was transferred to intensive care unit (ICU) due to hemodynamic instability and electrolyte derangements. On day 2 of ICU stay, patient became febrile, hypotensive, tachycardic, and his hypoxemia worsened with increased supplemental oxygen requirement. His electrocardiogram (ECG) was consistent with atrial fibrillation and covedtyped Brugada pattern. At the early hours of the subsequent day, patient developed first episode of asystolic cardiac arrest requiring cardiopulmonary resuscitations (CPR) and intubation leading to return of spontaneous circulation (ROSC) after 10 mins. Only 3 days after the initial cardiac arrest episode, patient suffered from another episode of asystolic cardiac arrest requiring CPR leading to return of normal sinus rhythm and ROSC. Patient had a successful recovery from COVID-19 pneumonia with no additional cardiac events during his hospitalization, and was subsequently extubated and discharged from hospital with close follow up monitoring. Reported cases of Brugada syndrome in Hispanic population are scarce. Covid-19 positive patients have a guarded prognosis when they require intubation with mechanical ventilation with no chances of survival when they suffer cardiac arrest requiring cardiopulmonary resuscitation. This stimulated us to report a case of Brugada syndrome presented in Hispanic man who recovered a deadly course of Covid-19 infection despite requiring intubation and complicated course by two rounds of cardiopulmonary resuscitation (CPR).","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130483982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Association: Apical Hypertrophic Cardiomyopathy with Multiple Coronary Artery-Left Ventricular Fistulae","authors":"Monedero-Sánchez Isabel, Robles-Velasco Pablo, Rubio-Caballero Amador, González-Doforno Yago, Marco-Quirós Cecilia, Espejo-Bares Victoria, Artiaga-de-la-Barrera Verónica, Jiménez-Martínez Carla","doi":"10.23937/2643-3966/1710045","DOIUrl":"https://doi.org/10.23937/2643-3966/1710045","url":null,"abstract":"A 59-year-old woman was referred for evaluation of chest pain and she was diagnosed of acute coronary syndrome. Coronary arteriography showed a severe stenosis of left anterior descending artery but also the presence of multiple coronary artery-left ventricle micro-fistulae. Echocardiographic findings were consistent with apical hypertrophic cardiomyopathy and the fistulae were also patent by colour Doppler echocardiography. Little is known about clinical features of micro-fistulae arising from both coronary arteries and emptying into left ventricle, especially when they are associated with apical hypertrophic cardiomyopathy.","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127066750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiac Arrhythmia Associated with Remdesivir in COVID-19","authors":"Niraula Sristee, Oli Shital, L. Janette","doi":"10.23937/2643-3966/1710046","DOIUrl":"https://doi.org/10.23937/2643-3966/1710046","url":null,"abstract":"","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132641354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Characteristics and Clinical Outcomes of Patients with Heart Failure Who Receive Public Assistance in Japan","authors":"Watanabe Shingo","doi":"10.23937/2643-3966/1710047","DOIUrl":"https://doi.org/10.23937/2643-3966/1710047","url":null,"abstract":"Background: The number of patients with heart failure (HF) is increasing, which is a socio-economic problem. Past overseas studies have reported that low-income patients with HF do not receive adequate treatment for financial reasons and have poor clinical outcomes. In Japan, medical expenses are free if they receive public assistance called Seikatsu hogo (PA), and there is no disadvantage to low-income patients regarding medical expenses. The purpose of this study is to investigate the clinical characteristics of patients with HF who receive PA in Japan. Methods: We enrolled 301 patients who were admitted to our hospital for the congestive HF. We divided patients into groups of patients receiving PA (PA group, N = 51) and groups of patients not receiving PA (Non-WPA group, N = 250). We compared patient clinical characteristics at admission, and the incidence of one-year cardiovascular events (cardiac death, readmission for HF) in both groups. Results: The PA group was significantly younger (71.1y ± 12.7 vs. 79.9y ± 12.4 P < 0.001) and more smokers (62.7% vs. 35.6% P < 0.001) than the Non-PA group. The left ventricular ejection fraction was significantly lower in the PA group than in the Non-PA group (34.6% ± 17.9 vs. 43.0% ± 18.7 P = 0.04). There was no significant difference in mortality between the two groups. The incidence of readmissions for HF was significantly higher in the PA group than in the Non-PA group (33.3% vs. 18.2% P = 0.02). Conclusion: Patients with HF who received public assistance had a poor cardiac function, and the incidence of readmission due to HF was high.","PeriodicalId":170730,"journal":{"name":"International Archives of Cardiovascular Diseases","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127250232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}