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C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES最新文献

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Cigarette Smoke Can Activate Fibroblast Growth Factor Signaling in Vascular Smooth Muscle Cells in the COPD Lung 吸烟可激活COPD肺血管平滑肌细胞中的成纤维细胞生长因子信号
C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4518
S. Krick, J. Garth, S. Helton, R. Denson, R. Zaharias, J. M. Wells, J. Barnes
{"title":"Cigarette Smoke Can Activate Fibroblast Growth Factor Signaling in Vascular Smooth Muscle Cells in the COPD Lung","authors":"S. Krick, J. Garth, S. Helton, R. Denson, R. Zaharias, J. M. Wells, J. Barnes","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4518","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4518","url":null,"abstract":"","PeriodicalId":170264,"journal":{"name":"C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127142172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinically Important Deterioration Among Patients with Chronic Obstructive Pulmonary Disease (COPD) Treated with Glycopyrrolate Eflow® Closed System (CS) (nebulized Glycopyrrolate) in Pooled Data from Two Randomized, Double Blind, Placebo-Controlled Studies 两项随机、双盲、安慰剂对照研究的合并数据显示，甘炔罗酸流®封闭系统(CS)(雾化甘炔罗酸)治疗慢性阻塞性肺疾病(COPD)患者的临床重要恶化
C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4524
E. Kerwin, L. Murray, V. Ganapathy, C. Dembek, K. Rajagopalan
{"title":"Clinically Important Deterioration Among Patients with Chronic Obstructive Pulmonary Disease (COPD) Treated with Glycopyrrolate Eflow® Closed System (CS) (nebulized Glycopyrrolate) in Pooled Data from Two Randomized, Double Blind, Placebo-Controlled Studies","authors":"E. Kerwin, L. Murray, V. Ganapathy, C. Dembek, K. Rajagopalan","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4524","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4524","url":null,"abstract":"","PeriodicalId":170264,"journal":{"name":"C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129049805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Characterization of A Human LPS Challenge Model 人LPS攻击模型的分子表征
C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4534
F. Heissig, T. Litzenburger, Meike Müller, K. Wetzel, K. Hohl, R. Schmid, W. Seibold, M. Sarno, Abhya Gupta, P. Badorrek, Cornelia Faulenbach, J. Hohlfeld
{"title":"Molecular Characterization of A Human LPS Challenge Model","authors":"F. Heissig, T. Litzenburger, Meike Müller, K. Wetzel, K. Hohl, R. Schmid, W. Seibold, M. Sarno, Abhya Gupta, P. Badorrek, Cornelia Faulenbach, J. Hohlfeld","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4534","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4534","url":null,"abstract":"","PeriodicalId":170264,"journal":{"name":"C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132261522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sputum Analysis by Chipcytometry Following LPS Inhalation Challenge 脂多糖吸入刺激后痰液的芯片细胞分析
C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4535
S. Carstensen, O. Holz, Meike Müller, J. Hohlfeld
{"title":"Sputum Analysis by Chipcytometry Following LPS Inhalation Challenge","authors":"S. Carstensen, O. Holz, Meike Müller, J. Hohlfeld","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4535","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4535","url":null,"abstract":"","PeriodicalId":170264,"journal":{"name":"C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130384034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vanadium Pentoxide Stimulate Inflammatory Response and Autophagy Via Activating ERK Pathway 五氧化二钒通过激活ERK通路刺激炎症反应和自噬
C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4543
S.-H. Lin, C.-H. Lin, Y.-R. Li, H. Chang, Y.-Y. Ching
{"title":"Vanadium Pentoxide Stimulate Inflammatory Response and Autophagy Via Activating ERK Pathway","authors":"S.-H. Lin, C.-H. Lin, Y.-R. Li, H. Chang, Y.-Y. Ching","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4543","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4543","url":null,"abstract":"","PeriodicalId":170264,"journal":{"name":"C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134643555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Short-Term Oral Prednisone Therapy on Blood Gene Expression 短期口服强的松治疗对血液基因表达的影响
C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4553
H. Takiguchi, V. Chen, M. Obeidat, Z. Hollander, J. M. Fitzgerald, B. McManus, N. Raymond, D. D. Sin
{"title":"Effect of Short-Term Oral Prednisone Therapy on Blood Gene Expression","authors":"H. Takiguchi, V. Chen, M. Obeidat, Z. Hollander, J. M. Fitzgerald, B. McManus, N. Raymond, D. D. Sin","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4553","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4553","url":null,"abstract":"","PeriodicalId":170264,"journal":{"name":"C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115446467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of a Novel ProteaseTag® Activity-Based Immunoassay for Quantification of Proteinase 3 in Sputum Sol Samples 新型ProteaseTag®活性免疫法定量痰液样品中蛋白酶3的验证
C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4532
T. Ferguson, K. Moffitt, D. Ramsay, C. Robb, Darragh Mccafferty, A. Kennedy, K. Dipetrillo, B. Walker
{"title":"Validation of a Novel ProteaseTag® Activity-Based Immunoassay for Quantification of Proteinase 3 in Sputum Sol Samples","authors":"T. Ferguson, K. Moffitt, D. Ramsay, C. Robb, Darragh Mccafferty, A. Kennedy, K. Dipetrillo, B. Walker","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4532","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4532","url":null,"abstract":"","PeriodicalId":170264,"journal":{"name":"C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116589354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and Safety of CHF6001, A Novel Inhaled PDE4 Inhibitor in COPD: The Pioneer Dose Finding Study 新型吸入PDE4抑制剂CHF6001治疗慢性阻塞性肺病的疗效和安全性:初步剂量发现研究
C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4529
D. Singh, M. A. Nandeuil, C. Pigeon-Francisco, A. Emirova, Debora Santoro, S. Biondaro, G. Cohuet, M. Govoni, S. Petruzzelli
{"title":"Efficacy and Safety of CHF6001, A Novel Inhaled PDE4 Inhibitor in COPD: The Pioneer Dose Finding Study","authors":"D. Singh, M. A. Nandeuil, C. Pigeon-Francisco, A. Emirova, Debora Santoro, S. Biondaro, G. Cohuet, M. Govoni, S. Petruzzelli","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4529","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4529","url":null,"abstract":"","PeriodicalId":170264,"journal":{"name":"C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122904320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Variant and Potentially Pathogenic Stem Cells in COPD Lung COPD肺中的变异和潜在致病性干细胞
C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4548
W. Xian, W. Rao, F. McKeon
{"title":"Variant and Potentially Pathogenic Stem Cells in COPD Lung","authors":"W. Xian, W. Rao, F. McKeon","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4548","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4548","url":null,"abstract":"","PeriodicalId":170264,"journal":{"name":"C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121523606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoantigen Array Reveals Decreased Expression of Autoantibodies in Sputum of Patients with Chronic Obstructive Pulmonary Disease 自身抗原阵列显示慢性阻塞性肺疾病患者痰中自身抗体表达降低
C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4551
S. Cass, A. Dvorkin-Gheva, J. McGrath, D. Thayaparan, M. Mukherjee, L. Quan-Zhen, Parameswaran Nair, Christopher S. Stevenson, M. Stämpfli
{"title":"Autoantigen Array Reveals Decreased Expression of Autoantibodies in Sputum of Patients with Chronic Obstructive Pulmonary Disease","authors":"S. Cass, A. Dvorkin-Gheva, J. McGrath, D. Thayaparan, M. Mukherjee, L. Quan-Zhen, Parameswaran Nair, Christopher S. Stevenson, M. Stämpfli","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4551","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4551","url":null,"abstract":"","PeriodicalId":170264,"journal":{"name":"C32. COPD: TRANSLATIONAL AND MECHANISTIC STUDIES","volume":"94 17","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131879687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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