Journal of Scientific Research in Science最新文献_第8页

Antifungal activity of Streptomyces canescens MH7 isolated from mangrove sediment against some dermatophytes 从红树林沉积物中分离的癌变链霉菌MH7对几种皮肤真菌的抑菌活性

Journal of Scientific Research in Science Pub Date : 2021-01-01 DOI: 10.21608/jsrs.2021.210676

Eman Elabbasy, Azhar Hussain, S. M. Ashour, S. Ibrahim

{"title":"Antifungal activity of Streptomyces canescens MH7 isolated from mangrove sediment against some dermatophytes","authors":"Eman Elabbasy, Azhar Hussain, S. M. Ashour, S. Ibrahim","doi":"10.21608/jsrs.2021.210676","DOIUrl":"https://doi.org/10.21608/jsrs.2021.210676","url":null,"abstract":"The main objective of this study is to isolate actinobacteria has antifungal activity against some dermatophytes, Epidermophyton floccosum, Trichophyton rubrum, Microsporum canis, and Candida albicans, evaluation, and optimization of various cultural and nutritional conditions for maximum antifungal metabolite production. Total 64 actinobacteria were isolated from various localities in Egypt and screened for their antifungal activity against the tested fungi. Out of 64 isolates, the identified Streptomyces canescens MH7 has a good antifungal activity and inhibits the growth of the tested fungi. This isolate was capable of producing glucanase, lipase, and amylase enzymes which are important hydrolytic enzyme in the lysis of the fungal cell wall. Several growth factors were optimized to maximize the production of antifungal metabolites. Streptomyces canescens MH7 had the best antifungal activity in starch casein broth media supplemented with starch as a carbon source, potassium nitrate as a nitrogen source, salinity of 3% (w/v), pH8, incubation temperature at 30°C, incubation for 7 days, and shaking at 180 rpm.","PeriodicalId":16981,"journal":{"name":"Journal of Scientific Research in Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84391119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

New modified chitosan composites and nanocomposites for different applications 新型改性壳聚糖复合材料和纳米复合材料的不同应用

Journal of Scientific Research in Science Pub Date : 2021-01-01 DOI: 10.21608/jsrs.2021.210669

T. Abdalla, Abir S. Nasr, Ghada Bassiuni, D. Harding, N. Kandile

{"title":"New modified chitosan composites and nanocomposites for different applications","authors":"T. Abdalla, Abir S. Nasr, Ghada Bassiuni, D. Harding, N. Kandile","doi":"10.21608/jsrs.2021.210669","DOIUrl":"https://doi.org/10.21608/jsrs.2021.210669","url":null,"abstract":"The present work focuses on the preparation of chitosan composite and chitosan nanocomposite derivatives for different applications. Chitosan was modified with bentonite or nano-bentonite to give chitosan composite and nanocomposite derivatives hydrogels I and II respectively, however chemical modification of chitosan with isonicotinic aldehyde via Schiff base formation in presence of bentonite or nanobentonite yielded chitosan composite and nanocomposite derivative hydrogels In and IIn respectively. The prepared hydrogels were characterized by Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (X-Ray), Thermogravimetric analysis (TGA), Differential Scanning Calorimetry (DSC), Scanning electron microscopy (SEM), and swelling behavior. Adsorption studies for removal of heavy metal ions from aqueous media and the biological activity for the new hydrogels were studied. Results of evaluation of the prepared chitosan derivatives hydrogel for metal ions uptake showed that the maximum adsorption capacity amounted to 68 and 22 mg/l and the highest efficiency for adsorption of cobalt and mercuric ions from aqueous solution by hydrogel IIn at 10 h (93.2%) and (97.8%) respectively, whereas the adsorption capacity of hydrogel IIn increased with the increase of the initial concentration of heavy metals ions ranging from 0.4 to 1 g/l. However, modified chitosan derivative hydrogels In and IIn showed remarkable MIC and MBC towards Gram-positive (B. subtilis) (19.5, 38) μg/ml compared to the standard antibiotic Ciprofloxacin (19, 38) μg/ml respectively.","PeriodicalId":16981,"journal":{"name":"Journal of Scientific Research in Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84847188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural Characterization, thermal studies, fluorescence and optical properties of metal carbonyl derivatives of N2O2 Schiff Base N2O2席夫碱金属羰基衍生物的结构表征、热研究、荧光和光学性质

Journal of Scientific Research in Science Pub Date : 2021-01-01 DOI: 10.21608/jsrs.2021.51182.1040

A. Amer, O. Ali, Doaa A. Nassar

引用次数: 0

An investigation of the mechanical properties of ternary blend cement pastes containing a large amount of cement kiln dust 含大量水泥窑尘的三元共混水泥浆体力学性能研究

Journal of Scientific Research in Science Pub Date : 2021-01-01 DOI: 10.21608/jsrs.2021.62382.1052

soher hashish, Doaa Abdel Monem Ahmed, sheren ragae

引用次数: 0

Efficiency of transgenic Chlamydomonas reinhardtii for removing of toxicity of cyanide compound. 转基因莱茵衣藻对氰化物的脱毒效果。

Journal of Scientific Research in Science Pub Date : 2021-01-01 DOI: 10.21608/jsrs.2021.210678

Rasha Elgammal, Y. El-Ayouty, Shaimaa S. Sobieh, Wafaa Sobhy Abu EL-Kheir, A. EL-Sheimy, A. Soror

引用次数: 0

Improvement of Phaseolus vulgaris growth by inoculation with multifunctional native rhizobacteria isolated from rhizospheric soils in Gaza strip- Palestine 用从加沙-巴勒斯坦根际土壤中分离的多功能原生根细菌接种提高菜豆生长

Journal of Scientific Research in Science Pub Date : 2020-06-01 DOI: 10.21608/jsrs.2020.129928

S. Abdelsalam, N. S. A. Hujier, F. Sharif, M. Fahd

{"title":"Improvement of Phaseolus vulgaris growth by inoculation with multifunctional native rhizobacteria isolated from rhizospheric soils in Gaza strip- Palestine","authors":"S. Abdelsalam, N. S. A. Hujier, F. Sharif, M. Fahd","doi":"10.21608/jsrs.2020.129928","DOIUrl":"https://doi.org/10.21608/jsrs.2020.129928","url":null,"abstract":"Overuse of chemical firtilizers is a global problem that had a negative impact on soil comosition and its microbial communities. The present study was conducted to isolate, identify plant growth promoting rhizobacteria (PGPR) associated with (Phaseolus vulgaris) in Gaza strip - Palestine and to determine bacterial inoculations/co-inoculations that can enhance plant growth. A total of 35 different morphological isolates were collected and examined for plant growth. Five isolates that were tentatively promising (in plant growth promoting traits i.e. IAA production, Zn solubilization, ACC deaminase activity and phytase production) , were selected and subjected to partial 16S rDNA gene sequencing. The five isolates were: Bacillus proteolyticus MK123398, Bacillus wiedmannii MK123399, Pseudomonas plecoglossicida MK123400, Pseudomonas cedrina MK123401 and Bacillus xiamenensis MK123402. Results indicated that some bacterial combinations significantly increased plant growth, but no significant increase of total nitrogen concentration was observed. Consortia of (B. proteolyticus + B. xiamenensis), (P. plecoglossicida + P. cedrina), (B. proteolyticus + B. wiedmannii + B. xiamenensis), (B. proteolyticus + P. plecoglossicida + B. xiamenensis), B. wiedmannii ), and (B. wiedmannii + P. plecoglossicida) showed significant increase in plant growth respectively. Those bacterial consortia have the potential for developing biofertilizers for integrated nutrient management strategies and decrease chemical firtilizers abuse stratiges.","PeriodicalId":16981,"journal":{"name":"Journal of Scientific Research in Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78628253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Reproductive Toxicity Induced by Low Dose Bisphenol A(BPA) in Male Rats 低剂量双酚A(BPA)对雄性大鼠生殖毒性的影响

Journal of Scientific Research in Science Pub Date : 2020-06-01 DOI: 10.21608/jsrs.2020.129939

sara elshafiey, M. Elgendy, M. Rashed, R. Ali, A. Kamel

{"title":"Reproductive Toxicity Induced by Low Dose Bisphenol A(BPA) in Male Rats","authors":"sara elshafiey, M. Elgendy, M. Rashed, R. Ali, A. Kamel","doi":"10.21608/jsrs.2020.129939","DOIUrl":"https://doi.org/10.21608/jsrs.2020.129939","url":null,"abstract":"Bisphenol A(BPA) an endocrine disruptor used in the manufacturing process of plastic. BPA low doses on long exposure periods had many hazardous effects.The aim of the present study was to assess the effect of lowest dose of BPA on the male induced orally on the at reproductive performance and changes in the testes that takes place histologically. P53 gene expression by Realtime PCR was also evaluated. Seventy- two albino male rats were divided into two groups, group I (control male rats receiving corn oil only). Group II (64 male rats) which was treated with oral doses of 50 µg/ kg/ day daily for 8 weeks. Every week 8 male rats were dissected and subjected to the investigated parameters. BPA treated groups presented decrease in sperms count, motility, progression and viability as well as a significant increase in sperms head or/and tail abnormalities were recognized. Histology of the testes showed abnormal and irregular organization of seminiferous tubules and decreased sperms in the testes lumen. Moreover, up-regulation in p53 expression was recorded after BPA exposure. In conclusion, these results showed that exposure to BPA at low dose 50µg/kg can cause many reproductive disorders which may impair fertility.","PeriodicalId":16981,"journal":{"name":"Journal of Scientific Research in Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81636382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Therapeutic role of MSCs-derived exosomes for Alzheimer's disease. msc来源的外泌体对阿尔茨海默病的治疗作用。

Journal of Scientific Research in Science Pub Date : 2020-06-01 DOI: 10.21608/jsrs.2020.96466

Sara M. Kamal, Aliaa Mostafa, S. Wahba

引用次数: 1

Suggested Study as a Treatment Protocol for Coronavirus 作为冠状病毒治疗方案的建议研究

Journal of Scientific Research in Science Pub Date : 2020-06-01 DOI: 10.21608/jsrs.2020.129935

M. Shahin

引用次数: 1

Preparation and characterization of silica hydrogel nanocomposites as a drug delivery system 二氧化硅水凝胶纳米复合材料给药系统的制备与表征

Journal of Scientific Research in Science Pub Date : 2020-02-01 DOI: 10.21608/jsrs.2020.129910

Noha Abdelazeem, El-Sayed R. El-Sayed, S. Abo-Naf, H. Abu-Zeid, G. Meligi

{"title":"Preparation and characterization of silica hydrogel nanocomposites as a drug delivery system","authors":"Noha Abdelazeem, El-Sayed R. El-Sayed, S. Abo-Naf, H. Abu-Zeid, G. Meligi","doi":"10.21608/jsrs.2020.129910","DOIUrl":"https://doi.org/10.21608/jsrs.2020.129910","url":null,"abstract":"Nowadays, the bacterial resistant infection risks to antibiotics have the limelight of developing new and natural antibacterial biomaterials. So, this work aimed to prepare drug carriers for Ceftriaxone (CFX) loading based on hydrogel nanocomposites for increasing the CFX loading capacity and improving the antibacterial properties of the hydrogels. Hence, a novel nanocomposites based on Ca-alginate hydrogels were prepared as antibacterial model. The morphology, textural, and the molecular interaction between the Mesoporous silica nanoparticles (MSNs) and the hydrogels were evaluated by using SEM, DCS, and FT-IR characterization techniques and loading efficiency was calculated. The loading efficiencies of (0, 5, 10 % MSNs) loaded with CFX were 2.379, 19.597 and 16.05 %, respectively. Furthermore, the antibacterial property of the hydrogels was tested by using colony forming test at three different loaded CFX concentrations. The results showed that, as MSNs % was increased in the alginate matrix, the loading CFX concentration increased. Thus, at 10% MSNs of 425.6 μg/ml CFX showed a significant viability % with (p** < 0.01) that was reached to 15.473% ± 0.399 relative to negative control. So, the hydrogels were to be used as a good CFX drug carrier and demonstrated a bactericidal effect against gram positive and gram negative bacteria.","PeriodicalId":16981,"journal":{"name":"Journal of Scientific Research in Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88192989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1