Archives of Medical Science - Civilization Diseases最新文献

{"title":"The effect of stump ligation techniques on operative time in laparoscopic appendectomy","authors":"N. Kutluer, A. Aksu, U. Aday, Hakan Kanat, A. Böyük, Serhat Doğan","doi":"10.5114/AMSCD.2021.107846","DOIUrl":"https://doi.org/10.5114/AMSCD.2021.107846","url":null,"abstract":"Introduction: We aimed to the of ligation techniques on Material The underwent laparoscopic appendectomy in our General Surgery Clinic January 2016 and August 2018 were retrospectively reviewed. The effects of stump ligation techniques used in the operations on operative times were evaluated. Results: Sixty consecutive patients were screened and 3 groups, 20 patients in each group, were formed based on stump ligation techniques. Extracorporeal knotting – loop ligation was used in Group 1; intracorporeal knotting was used in the Group 2; hem-o-lok clip was used in Group 3.There was no statistically significant difference between the groups in terms of gender distribution and mean age. However, there was a significant difference between the hem-o-lok clip group (Group III) and the intracorporeal knot group (Group II) in terms of operative time. Group III had a shorter operative time. The Group III patients had the shortest operative time, while the Group II patients had the longest operative time ( p < 0.05). Conclusions: We can speculate that hem-o-lok clip among the stump ligation techniques reduces the cost, is a safe method and shortens the operative time. However, prospective randomized studies with a large sample size comparing different techniques are needed to determine the ideal treat-ment procedure. At the same time, stapler use may be considered in cases where the base of the appendix is too inflamed or necrosed. It is known that the use of a stapler and endoloop is more expensive than all other techniques. However, the most important issue for the surgeon is patient safety; therefore the most appropriate technique should be preferred.","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"16 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132436011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PNPLA3 gene polymorphism and severity of liver steatosis and fibrosis","authors":"M. Wawrzynowicz-Syczewska, Aleksandra Waszczyk, D. Bander, J. Miętkiewski, A. Urbańska, Kaja Scheibe","doi":"10.5114/AMSCD.2021.105522","DOIUrl":"https://doi.org/10.5114/AMSCD.2021.105522","url":null,"abstract":"Introduction: Non-alcoholic fatty liver disease (NAFLD) is one of the leading chronic liver diseases worldwide. Environmental and genetic factors have an impact on NAFLD development. Single nucleotide polymorphism in the PNPLA3 gene is strongly related to the increased fat content in hepatocytes. The aim of our study was to investigate the association between PNPLA3 variants and the intensity of liver steatosis and fibrosis assessed by liver biopsy in patients with NAFLD. Material and methods: The study group comprised 127 patients with NAFLD confirmed by liver biopsy. The control group comprised 251 healthy volunteers. In every case genotyping of the PNPLA3 rs738409 C to G nonsynonymous sequence variant was performed. Distributions of genotypes and alleles were compared between NAFLD patients and controls, and analyzed in relation to different steatosis and fibrosis stages in the study group. Results: Frequencies of PNPLA3 genotypes strongly differ between NAFLD patients and controls (p = 0.00001). Odds ratio (OR) for genotype GG in NAFLD was 2.94 (1.45–5.97, p = 0.0015). Also allele G was more frequent in NAFLD patients vs. controls (p = 0.00001); OR for G allele in NAFLD was 2.74 (1.77–4.27, p = 0.00000273). No significant differences in the genotype or allele distribution of PNLPA3 were observed in relation to steatosis intensity or between patients with or without cirrhosis. However, allele G was found is every hepatocellular carcinoma case. Conclusions: We do not advocate universal genetic testing in every NAFLD case to select patients at risk of development of cirrhosis or steatohepatitis. Further investigation of the relationship between PNPLA3 variants and hepatocellular carcinoma is warranted.","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124097685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subjective evaluation of the effectiveness \u0000of treatment of chronic obstructive pulmonary disease – a qualitative study (Warsaw, Poland)","authors":"Dominika Ponikowska, A. Dworakowska, Edyta Czepielewska, M. Kozłowska-Wojciechowska","doi":"10.5114/amscd.2022.119597","DOIUrl":"https://doi.org/10.5114/amscd.2022.119597","url":null,"abstract":"","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128085011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concomitant laparoscopic sleeve gastrectomy and laparoscopic cholecystectomy in a morbidly obese patient with situs inversus totalis","authors":"V. Yiğit, Kenan Binnetoğlu, M. Dinçer","doi":"10.5114/AMSCD.2021.105387","DOIUrl":"https://doi.org/10.5114/AMSCD.2021.105387","url":null,"abstract":"Situs inversus totalis (SIT) is a rare congenital condition in which the major visceral organs within the thorax and abdomen are reversed from their normal positions. Its incidence is 1 in 10 000–50 000 of the popu-lation It presents difficulties in laparoscopic surgery, because of the mirror-image anatomy. Laparoscopic surgical treatments of some condi-tions in patients with situs inversus totalis such as acute appendicitis, cholelithiasis, and morbid obesity have been previously Herein we report a case of situs inversus totalis treated with concomitant laparoscopic sleeve gastrectomy (LSG) and laparoscopic cholecystectomy (LC).","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129915011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antithrombotic/antiplatelet therapy and colonoscopy results in patients over 50 with iron-deficiency anemia","authors":"Tolga Olmez, Hilmi Bozkurt, Selçuk Gülmez, E. Aray, Z. O. Sert, E. Kaplan, C. Bulut, Erdal Karakose, E. Polat, M. Duman","doi":"10.5114/amscd.2019.86738","DOIUrl":"https://doi.org/10.5114/amscd.2019.86738","url":null,"abstract":"Introduction: This study aims to evaluate the results of asymptomatic patients who have been using anticoagulant-antiaggregant (AC-AA) agents and have had colonoscopy screening due to iron-deficiency anemia (IDA). Material and methods: The data of 347 asymptomatic patients over the age of 50, who have received colonoscopy due to IDA, were reviewed retrospectively. The effects of sex and AC-AA administration on positive colonoscopy results, preneoplastic lesions and malignancy were investigated. Results: Of 347 patients over 50 with IDA, 204 were female (58.8%). The mean age was 63.4 ±8.4. Positive colonoscopy results were observed more commonly in 69 male patients compared to 67 female patients ( p = 0.004). Similarly, positive colonoscopy results were found to be more frequent among patients using AC-AA ( p = 0.019). While premalignant lesions were more frequently diagnosed in male patients (23% to 10.2%), the results were also statistically significant ( p = 0.002). Anticoagulant administration did not contribute to the increase in preneoplastic lesion rates (15.57% to 15.55%). Malignant pathology, which was seen in 8 male patients, was more common among male patients yet it was not statistically significant ( p = 0.081). However, compared to 3 patients who did not use AC-AA, malignant pathology was seen more frequently in 9 patients who were on AC-AA and the figure was statistically significant ( p = 0.009). Conclusions: The AC-AA administration in asymptomatic patients over 50 with IDA who have had colonoscopy screening increases the rate of colorectal malignancy diagnosis, while it leads to no change in the rate of preneoplastic lesion detection. Nevertheless, male sex is a factor that increases the possibility of preneoplastic lesion detection. in analyses for age groups, the differences between binary groups were compared using the c 2 test. P -value ≤ 0.05 was set to be statistically significant. Logistic regression analysis was used in values affecting colonoscopy results.","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133005101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}