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Journal of Radiation and Cancer Research最新文献

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Study on Dosimetric Superiority of Forward Planned Intensity-Modulated Radiotherapy Treatment of Thoracic Esophageal Squamous Cell Carcinoma 前计划调强放疗治疗胸段食管鳞状细胞癌剂量学优势研究
Journal of Radiation and Cancer Research Pub Date : 2023-01-01 DOI: 10.4103/jrcr.jrcr_71_22
S. Rather, M. Banday, S. Wani, Aijaz A. Khan, M. Shah, T. Tali, F. Mir, M. A. Badhul Haq
{"title":"Study on Dosimetric Superiority of Forward Planned Intensity-Modulated Radiotherapy Treatment of Thoracic Esophageal Squamous Cell Carcinoma","authors":"S. Rather, M. Banday, S. Wani, Aijaz A. Khan, M. Shah, T. Tali, F. Mir, M. A. Badhul Haq","doi":"10.4103/jrcr.jrcr_71_22","DOIUrl":"https://doi.org/10.4103/jrcr.jrcr_71_22","url":null,"abstract":"","PeriodicalId":16923,"journal":{"name":"Journal of Radiation and Cancer Research","volume":"9 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75750087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Different Evaluation Indexes for Postoperative Brain Cancer Radiation Therapy Plans: Conformity Index, Homogeneity Index, and Total Coverage Index 脑癌术后放疗方案不同评价指标的分析:符合性指数、均匀性指数和总覆盖指数
Journal of Radiation and Cancer Research Pub Date : 2023-01-01 DOI: 10.4103/jrcr.jrcr_91_22
S. Rather, M. Banday, Samina Mufti, MustaqAhmad Sofi, MisbhaHamid Baba
{"title":"Analysis of Different Evaluation Indexes for Postoperative Brain Cancer Radiation Therapy Plans: Conformity Index, Homogeneity Index, and Total Coverage Index","authors":"S. Rather, M. Banday, Samina Mufti, MustaqAhmad Sofi, MisbhaHamid Baba","doi":"10.4103/jrcr.jrcr_91_22","DOIUrl":"https://doi.org/10.4103/jrcr.jrcr_91_22","url":null,"abstract":"","PeriodicalId":16923,"journal":{"name":"Journal of Radiation and Cancer Research","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79759291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Augmented Immune-Staining of G-Quadruplex Tertiary DNA Structure in Chemo-Tolerant TNBC with Downregulation of WNT/Epidermal Growth Factor Receptor Pathway receptor Genes: A Pilot Clinicopathological Study 耐化疗TNBC中g -四联体三级DNA结构增强免疫染色与WNT/表皮生长因子受体通路受体基因下调的关联:一项初步临床病理研究
Journal of Radiation and Cancer Research Pub Date : 2023-01-01 DOI: 10.4103/jrcr.jrcr_23_22
Saimul Islam, Mukta Basu, A. Roy, N. Alam, C. Panda
{"title":"Association of Augmented Immune-Staining of G-Quadruplex Tertiary DNA Structure in Chemo-Tolerant TNBC with Downregulation of WNT/Epidermal Growth Factor Receptor Pathway receptor Genes: A Pilot Clinicopathological Study","authors":"Saimul Islam, Mukta Basu, A. Roy, N. Alam, C. Panda","doi":"10.4103/jrcr.jrcr_23_22","DOIUrl":"https://doi.org/10.4103/jrcr.jrcr_23_22","url":null,"abstract":"Purpose: The aim of the study is to understand the involvement of G-Quadruplex (G-Q) structures in altering the expression profile of WNT/epidermal growth factor receptor (EGFR) pathway receptor genes in chemo-tolerant Triple Negative Breast Cancer (TNBC) samples. Materials and Methods: At first, Gene Expression Omnibus datasets were mined where the expression profile of WNT/EGFR pathway genes in TNBC samples and MDA-MB-231, a TNBC cell line, were checked in response to doxorubicin, a chemotherapeutic drug. Next, to unveil the probable mechanism of regulation, the presence of G-Q structure was checked in in silico study and later validated by immunohistochemical analyses in our pool of sample. These observed results were correlated with patient's demography and survival status. Results: Expression of the receptors (FZD7, LRP6, EGFR) of the WNT/EGFR pathway were found to be differentially expressed in TNBC samples; further emphasized in our samples (n = 61). Notably, these G-Q structures were found in the promoter region of the WNT pathway receptor genes (FZD7, LRP6, and EGFR). Validating in our patient sample pool, a significant increase in G-Q immunostaining was observed in samples, after neoadjuvant chemotherapy (NACT) samples (n = 17) than the pretherapeutic samples (n = 44). Similar pattern of G-Q immunostaining was noticed in doxorubicin-treated MDA-MB-231 cell line. Intriguingly, low staining of G-Q among the pretherapeutic samples, but NACT TNBC samples, was found to be significantly correlated with lymph node metastasis. Conclusions: This study showed that the augmented immunostaining of G-Q structure might have an important involvement in regulating the expression pattern of the WNT/EGFR pathway genes in response to doxorubicin treatment of TNBC.","PeriodicalId":16923,"journal":{"name":"Journal of Radiation and Cancer Research","volume":"2 1","pages":"14 - 20"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78607597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remembering Dr. Bam Bahadur Singh: An outstanding Scientist and a learned lawyer 纪念巴姆·巴哈杜尔·辛格博士:一位杰出的科学家和一位博学的律师
Journal of Radiation and Cancer Research Pub Date : 2023-01-01 DOI: 10.4103/jrcr.jrcr_9_23
KP Mishra
{"title":"Remembering Dr. Bam Bahadur Singh: An outstanding Scientist and a learned lawyer","authors":"KP Mishra","doi":"10.4103/jrcr.jrcr_9_23","DOIUrl":"https://doi.org/10.4103/jrcr.jrcr_9_23","url":null,"abstract":"","PeriodicalId":16923,"journal":{"name":"Journal of Radiation and Cancer Research","volume":"2009 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82615987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An observational study of diffusion-wssseighted imaging characteristics in patients with cervical cancer 宫颈癌患者弥漫性影像特征的观察研究
Journal of Radiation and Cancer Research Pub Date : 2023-01-01 DOI: 10.4103/jrcr.jrcr_22_23
Hitesh Sinduriyan, Rachit Sharma, GauravPratap Singh Gahlot
{"title":"An observational study of diffusion-wssseighted imaging characteristics in patients with cervical cancer","authors":"Hitesh Sinduriyan, Rachit Sharma, GauravPratap Singh Gahlot","doi":"10.4103/jrcr.jrcr_22_23","DOIUrl":"https://doi.org/10.4103/jrcr.jrcr_22_23","url":null,"abstract":"","PeriodicalId":16923,"journal":{"name":"Journal of Radiation and Cancer Research","volume":"266 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76742950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Significance of physical activity and exercise in cancer patients: A review on exercise oncology 体育活动和运动对癌症患者的意义:运动肿瘤学研究综述
Journal of Radiation and Cancer Research Pub Date : 2023-01-01 DOI: 10.4103/jrcr.jrcr_57_22
J. Dar, T. Tali, Fiza Amin, NazirAhmad Khan, N. Dar
{"title":"Significance of physical activity and exercise in cancer patients: A review on exercise oncology","authors":"J. Dar, T. Tali, Fiza Amin, NazirAhmad Khan, N. Dar","doi":"10.4103/jrcr.jrcr_57_22","DOIUrl":"https://doi.org/10.4103/jrcr.jrcr_57_22","url":null,"abstract":"","PeriodicalId":16923,"journal":{"name":"Journal of Radiation and Cancer Research","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79739261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasmacytoma of nasopharynx - A rare case presentation treated with volumetric modulated arc technique radiotherapy 鼻咽部浆细胞瘤-用体积调制弧线技术放射治疗的罕见病例
Journal of Radiation and Cancer Research Pub Date : 2023-01-01 DOI: 10.4103/jrcr.jrcr_6_22
Sujata Sarkar, I. Bashir, R. Yotham, Ritesh Sharma
{"title":"Plasmacytoma of nasopharynx - A rare case presentation treated with volumetric modulated arc technique radiotherapy","authors":"Sujata Sarkar, I. Bashir, R. Yotham, Ritesh Sharma","doi":"10.4103/jrcr.jrcr_6_22","DOIUrl":"https://doi.org/10.4103/jrcr.jrcr_6_22","url":null,"abstract":"Extramedullary plasmacytomas (EMPs) are solitary plasma cell neoplasms that involve sites other than bone or bone marrow. It constitutes only 0.4% of tumors of head-and-neck region. Surgery and radiotherapy are standard treatment, depending on the site. Radiotherapy promises 90–100% local control rate and prolonged survival. Here, we are reporting a case of plasmacytoma nasopharynx treated with volumetric-modulated arc technique (VMAT) radiotherapy, with contouring details, dose to target, and nearby structures. Patient had complete response and is relapse free for the past 3 years with minimal toxicity. In our case, the lesion is in nasopharynx and is about 1cm, as such it required precise radiotherapy technique like VMAT, to give targeted dose delivery and sparing the nearby critical organs.","PeriodicalId":16923,"journal":{"name":"Journal of Radiation and Cancer Research","volume":"54 1","pages":"43 - 45"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74965428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synchronous squamous cell carcinoma of the hypopharynx and adenocarcinoma of the lung: A report of two cases treated with definitive radiotherapy 下咽同步鳞状细胞癌伴肺腺癌:2例放疗治疗报告
Journal of Radiation and Cancer Research Pub Date : 2023-01-01 DOI: 10.4103/jrcr.jrcr_13_23
J. Nath, M. Bhattacharyya, Saswati Datta, Shiraj Ahmed, J. Das, Yanpothung Yanthan
{"title":"Synchronous squamous cell carcinoma of the hypopharynx and adenocarcinoma of the lung: A report of two cases treated with definitive radiotherapy","authors":"J. Nath, M. Bhattacharyya, Saswati Datta, Shiraj Ahmed, J. Das, Yanpothung Yanthan","doi":"10.4103/jrcr.jrcr_13_23","DOIUrl":"https://doi.org/10.4103/jrcr.jrcr_13_23","url":null,"abstract":"","PeriodicalId":16923,"journal":{"name":"Journal of Radiation and Cancer Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89835568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Excitements in radiobiology 放射生物学的兴奋
Journal of Radiation and Cancer Research Pub Date : 2022-10-01 DOI: 10.4103/jrcr.jrcr_76_22
KP Mishra
{"title":"Excitements in radiobiology","authors":"KP Mishra","doi":"10.4103/jrcr.jrcr_76_22","DOIUrl":"https://doi.org/10.4103/jrcr.jrcr_76_22","url":null,"abstract":"","PeriodicalId":16923,"journal":{"name":"Journal of Radiation and Cancer Research","volume":"15 1","pages":"143 - 145"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90877414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changing treatment paradigms of radiotherapy for the treatment of lung cancer 改变放疗治疗肺癌的治疗模式
Journal of Radiation and Cancer Research Pub Date : 2022-10-01 DOI: 10.4103/jrcr.jrcr_5_22
Atsuto Katano
{"title":"Changing treatment paradigms of radiotherapy for the treatment of lung cancer","authors":"Atsuto Katano","doi":"10.4103/jrcr.jrcr_5_22","DOIUrl":"https://doi.org/10.4103/jrcr.jrcr_5_22","url":null,"abstract":"Lung cancer is largely classified into two types according to its histology, small cell and nonsmall cell, and has diverse situations for which radiotherapy is indicated. Radiation therapy plays a major role in the treatment strategy for both types of lung cancer. Since the treatment of lung cancer is extremely complex, it is essential to develop an appropriate treatment strategy by combining surgery, radiotherapy, and systemic therapy (chemotherapy, immunotherapy, and molecular-targeted drugs) according to each stage of the disease. Radiotherapy is indicated, from curative intent to palliative treatment, at any stage of the disease. Current radiotherapy, which incorporates diagnostic imaging and physical engineering, has made significant progress, making it possible to increase the local control rate while reducing the radiation dose to at-risk organs. Herein, we review the basics of the current perspective of radiotherapy and the current role of radiotherapy in lung cancer treatment according to each stage of the disease.","PeriodicalId":16923,"journal":{"name":"Journal of Radiation and Cancer Research","volume":"106 1","pages":"232 - 236"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87867334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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