{"title":"Computer system for metrological testing of location sensors used to monitor the patient's condition in magnetotherapy","authors":"S. G. Gurzhin, V. L. Nguyen, A. V. Shulyakov","doi":"10.18127/j15604136-202104-02","DOIUrl":"https://doi.org/10.18127/j15604136-202104-02","url":null,"abstract":"Non-contact monitoring of vital signs of a person is a reliable and safe way of promptly obtaining objective diagnostic information about the current physiological state of a patient during surgical operations, physiotherapeutic procedures or during sleep. The absence of direct contact of the sensors with the patient's body makes it possible to exclude the influence of a number of interfering factors, such as a violation or weakening of contact, which can lead to a deterioration in the quality of signals from the output of the sensors, a long-term location of the sensors on the body can have a psychological effect on the patient, changing his condition and thereby distorting the treatment method, etc. In order for the results of monitoring and diagnostics to be reliable and guaranteed accurate, it is necessary to carry out periodic metrological certification of location sensors, especially since many of them are of foreign production and their characteristics are either not standardized or do not meet the requirements of their operating conditions. Therefore, the tasks of developing methods and means for carrying out metrological tests of non-contact sensors for medical purposes are becoming urgent. Purpose – to show the possibility of implementing automated metrological tests of location sensors for medical use based on a personal computer and publicly available standard hardware and software. A method has been developed and implemented for conducting metrological tests of location sensors based on a personal computer, a digital dynamic measure of linear displacement, virtual measuring instruments, laser and ultrasonic sensors, as well as determining conversion errors in the LabVIEW environment. As an exemplary measuring instrument, it is proposed to use a webcam with a virtual device for recording the law of displacement in the LabVIEW Vison Development application. Full-scale experiments have been carried out, in which, using a digital measure of linear displacement, it is possible to reproduce with high accuracy almost any law of displacement and to regulate its informative parameters. Real movement signals were received with the help of virtual devices, recorded by two location sensors and a web camera. The errors of the means of registration are determined in comparison with the given digital method and analytically the law of movement. Introduction of the developed method and hardware and software for metrological certification of sensors of diagnostic channels of the systems of complex magnetotherapy «Multimag» and «Relaxmag». Carrying out automated metrological tests of sensors will ensure prompt, reliable and objective control of their actual characteristics, which means it will increase the effectiveness of treatment due to the prompt and continuous monitoring of the patient's functional state and an objective assessment of a number of important indicators.","PeriodicalId":169108,"journal":{"name":"Biomedical Radioelectronics","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128270417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Akopyan, V. Gorshenev, E. Budoragin, M. V. Bambura, M. Dragún
{"title":"Synthesis of biocompatible calcium-phosphate compositions in ultrasound field","authors":"V. Akopyan, V. Gorshenev, E. Budoragin, M. V. Bambura, M. Dragún","doi":"10.18127/j15604136-202105-07","DOIUrl":"https://doi.org/10.18127/j15604136-202105-07","url":null,"abstract":"Introduction reflects the great interest of practical restorative medicine in artificial structures that mimic the structure and properties of natural bone tissue that are made from biocompatible composite materials suitable for restoring the integrity of bone elements of the musculoskeletal system. The Introduction also contains the physicochemical foundations and approaches to a new ultrasonic technologies providing accelerated production of a biocompatible composite material, precisely hydroxyapatite particles in a collagen matrix. Experimental part contains a description of methods and equipmets for accelerated production of a hydroxyapatite suspension in the field of a hydroacoustic emitter, which ensures that the cavitation threshold at room temperature is exceeded, at which intense acoustic vortex microflows provide a decrease in diffusion restrictions, accelerating the interaction between reacting components. The reaction is carried out with the simultaneous supply of an aqueous solution of calcium monophosphate hydrate and a suspension of calcium hydroxide. The resulting finished product is separated using an ultrasonic self-cleaning filter, where the same, by nature, microflows allow the implementation of a continuous accelerated separation of synthesized particles in an ultrasonic self-cleaning filter of the installation, where, after separation, the precipitate is also subjected to cleaning. The resulting particles of hydroxyapatite mixed with the solution collagen and homogenized in an ultrasonic field at frequency of 22 kHz and an energy density in the reaction volume from 1 to 10 W / cm3. Obtained homogenate can be easily used to create various implant designs with predetermined sizes and shapes and after freezedrying was transformed in biocompatible composite with a porous structure. To control biocompatibility, samples of this composite in form of thin plate was sewed under the skin into the scruff of white lab rats. A suspension of hydroxyapatite mechanically combined with the collagen during 30 s homogenization by ultrasound at frequency of 22 kHz and at energy density of 3 W / cm3, form a complex that is freeze-dried, after which it can be used to form the biocomposite body with porous structure and with given dimensions and shapes. Subcutaneous implantation of plates of a calcium-phosphate biocomposite with a biodegradable polymer collagen, into the scruff of a laboratory white mouse showed its good biocompatibility with tissues of a living organism, without causing either immediate or delayed adverse events in them.","PeriodicalId":169108,"journal":{"name":"Biomedical Radioelectronics","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128827094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. D. Litvin, O. Dadasheva, S.A Pinegin, T. Gurieva, E. I. Mednikova, A. Spassky, V. Lebedev, V. Sychev
{"title":"The influence of hypomagnetic environmental conditions on the reproductive function of male Japanese quail (Caturnix japonica) in three consecutive generations","authors":"E. D. Litvin, O. Dadasheva, S.A Pinegin, T. Gurieva, E. I. Mednikova, A. Spassky, V. Lebedev, V. Sychev","doi":"10.18127/j15604136-202201-07","DOIUrl":"https://doi.org/10.18127/j15604136-202201-07","url":null,"abstract":"","PeriodicalId":169108,"journal":{"name":"Biomedical Radioelectronics","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127009910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biological object and magnetic field concentrator","authors":"L. Morozova, S. V. Savel’ev","doi":"10.18127/j15604136-202201-04","DOIUrl":"https://doi.org/10.18127/j15604136-202201-04","url":null,"abstract":"","PeriodicalId":169108,"journal":{"name":"Biomedical Radioelectronics","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125511823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of fuzzy inference rules for a model of integrated interpretation of cardiorhythmogram signal features","authors":"Y. Chelebaeva, O. Melnik, S. V. Chelebaev","doi":"10.18127/j15604136-202204-11","DOIUrl":"https://doi.org/10.18127/j15604136-202204-11","url":null,"abstract":"","PeriodicalId":169108,"journal":{"name":"Biomedical Radioelectronics","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131701985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Makhov, G. S. Razmakhaev, E. Slavnova, A. Samorodov
{"title":"Biotechnical system for automated HER2-status determination in breast cancer via fluorescent in situ hybridization (FISH)","authors":"D. Makhov, G. S. Razmakhaev, E. Slavnova, A. Samorodov","doi":"10.18127/j15604136-202205-07","DOIUrl":"https://doi.org/10.18127/j15604136-202205-07","url":null,"abstract":"","PeriodicalId":169108,"journal":{"name":"Biomedical Radioelectronics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116269300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Filter selection for image processing before the landmark detection stage for micro-expression analysis","authors":"O. Melnik, V. Sablina, G. Burresi, A. V. Savin","doi":"10.18127/j15604136-202104-06","DOIUrl":"https://doi.org/10.18127/j15604136-202104-06","url":null,"abstract":"The automated estimation of the psycho-emotional state of the human and their emotional reactions to the different influences using the video image analysis is an urgent task in different fields, such as: safeguarding in manufacturing, aviation, transportation, prevention of the crimes and terroristic threats, marketing researches etc. A promising direction is the facial micro-expression analysis. The facial micro-expressions are not under conscious control and reflect the objective emotional reaction. One of the key stages of the procedure of the automatic emotion estimation by the facial micro-expressions is the correct facial landmark detection. It is a complex task because of the presence of the different noise in the consecutive frames. Purpose – the investigation of the ways of increasing the performance of the facial micro-expression analysis pipeline by using preliminary video image processing procedures. It is shown that, as the preliminary stage of the micro-expression analysis pipeline, it is reasonable to perform the blurring of the original images to obtain the more stable results. The determined filtering parameters provide the MediaPipe framework a performance increase for the micro-expression analysis problems. It is shown that the video image blurring by the Gaussian filter with a size of 15×15 pixels allows to reduce the noise influence and to decrease the incorrect shifts of the facial landmarks from frame to frame induced by this noise. The proposed procedure of preliminary video image processing can be used for increasing the facial micro-expression recognition performance in emotion recognition systems based on the video sequence analysis.","PeriodicalId":169108,"journal":{"name":"Biomedical Radioelectronics","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128577011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Action to an ultra-wideband electromagnetic field for pharmacological Pantovegin","authors":"L. Morozova, S. V. Savel’ev","doi":"10.18127/j15604136-202206-09","DOIUrl":"https://doi.org/10.18127/j15604136-202206-09","url":null,"abstract":"","PeriodicalId":169108,"journal":{"name":"Biomedical Radioelectronics","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121591153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of neural network model for signs determination of atrial fibrillation for subsystem of cardiorhythmogram signals processing","authors":"Y. Chelebaeva","doi":"10.18127/j15604136-202104-13","DOIUrl":"https://doi.org/10.18127/j15604136-202104-13","url":null,"abstract":"Task of the analysis of a cardio rhythm in real time is detection of early arrhythmias for the purpose of their treatment and prevention of life-endangering arrhythmias. In order to solve the problem of classification of heart rhythm features based on cardiorhythmogram processing, an apparatus of artificial neural networks can be used. One of the most dangerous arrhythmias is atrial fibrillation. Therefore, the development of a neural network model for determining atrial fibrillation features, suitable for implementation on the programmable logic basis, for a subsystem for processing cardiorhythmogram signals is an urgent task. Purpose – development of a neural network model for determining atrial fibrillation features for a signal processing subsystem characterized by high reliability and the implementation possibility on the basis of programmable logic. A neural network model for features determining of atrial fibrillation has been developed, characterized by high reliability and insignificant hardware costs when implemented on field programmable gate arrays (FPGA). Program modeling of neural network model for signs determination of atrial fibrillation is performed. A neural network model for characteristics determining of atrial fibrillation on hardware description language VHDL for use in the signal processing subsystem of a cardiorhythmogram based on FPGA was implemented. The findings suggest that the proposed model can be used in the construction of real-time heart rhythm control systems both for monitoring already diagnosed cardiovascular diseases, especially in intensive care wards, and for the prevention and early diagnosis of arrhythmias in individuals at high myocardial risk.","PeriodicalId":169108,"journal":{"name":"Biomedical Radioelectronics","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126413244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}