Journal of prosthodontic research最新文献

{"title":"Effect of thermal cycling on the flexural properties of resin composite and PEEK CAD-CAM blocks for molar crowns.","authors":"Yukako Kato, Shunsuke Nagata, Yasuhiro Tanimoto","doi":"10.2186/jpr.JPR_D_25_00235","DOIUrl":"https://doi.org/10.2186/jpr.JPR_D_25_00235","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluates and compares the flexural properties of computer-aided design-computer-aided manufacturing (CAD-CAM) resin composite and polyetheretherketone (PEEK) blocks used for molar crowns under three storage conditions. Furthermore, the relationship between the inorganic filler content (>70 wt. %) and the flexural properties of the resin composite blocks was clarified.</p><p><strong>Methods: </strong>Five commercially available resin composite blocks and one PEEK block were subjected to three storage conditions: dry storage, water immersion for 7 d at 37 °C, and 10,000 thermal cycles between 5 and 55 °C. The flexural strength and flexural modulus were analyzed using two-way ANOVA, followed by Tukey's post-hoc comparisons. The inorganic filler content and water sorption were analyzed via one-way ANOVA and the Tukey-Kramer post-hoc test, with the level of significance set at 5%.</p><p><strong>Results: </strong>The resin composite blocks exhibited a significantly higher flexural strength and flexural modulus than the PEEK block. A positive correlation was observed between the inorganic filler content and the flexural properties of the CAD-CAM blocks, specifically for the flexural strength (r = 0.49) and flexural modulus (r = 0.63). However, the PEEK block exhibited the lowest water sorption and minimal flexural properties changes across all conditions, as compared to the resin composite blocks.</p><p><strong>Conclusions: </strong>Both the inorganic filler content and matrix resin composition influenced the flexural properties of the CAD-CAM crown materials. PEEK demonstrated superior durability under thermal and humid conditions, indicating its potential as a long-term restorative material for posterior crowns.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Titanium-adhesive vitronectin promotes peri-implant bone formation via cell adhesion acceleration: An experimental study.","authors":"Haruka Takeuchi, Yosuke Akiba, Nguyen Van Quang, Kaori Eguchi, Nami Akiba, Ochoa Escate Dagny, Miho Terunuma, Jun Mizuno","doi":"10.2186/jpr.JPR_D_25_00199","DOIUrl":"https://doi.org/10.2186/jpr.JPR_D_25_00199","url":null,"abstract":"<p><strong>Purpose: </strong>Osseointegration begins at the initial blood-implant contact; however, titanium-adhesive blood proteins remain incompletely defined. We used a structure-free, nano-smooth titanium substrate (Ra ≈ 0.6 nm) to identify titanium-adhesive blood proteins and determine whether coating such proteins modulates cell adhesion, osteogenic differentiation, and peri-implant bone formation.</p><p><strong>Methods: </strong>Whole blood from Sprague-Dawley rats was seeded on nano-smooth titanium, followed by stringent washing. Adherent proteins were recovered and analyzed using LC-MS/MS and STRING-based bioinformatics screening. Vitronectin was identified as a major titanium-adhesive protein and functionally evaluated using a recombinant protein. Bone marrow stromal cell (BMSC) adhesion, osteogenic gene expression, mineralization, and peri-implant bone formation were assessed in a rat model. Phosphate-buffered saline (PBS)-treated, albumin-coated, and fibronectin-coated titanium surfaces were used as controls.</p><p><strong>Results: </strong>The vitronectin coating significantly enhanced early BMSC adhesion compared to all control surfaces, whereas fibronectin and albumin demonstrated no effect. Vitronectin did not alter osteogenic gene expression or mineralization in vitro but significantly accelerated peri-implant bone formation in vivo.</p><p><strong>Conclusions: </strong>Vitronectin exhibits physicochemical affinity for nano-smooth titanium and promotes peri-implant bone formation, primarily by accelerating early cell adhesion rather than by directly stimulating osteogenic differentiation.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of multiple use of titanium and PEEK scan bodies on scan precision after sterilization and thermal disinfection: An in vitro study.","authors":"Elisabeth Völler, Jan-Frederik Güth, Sebastian Heuser, Oliver Schubert, Josef Schweiger, Tobias Graf","doi":"10.2186/jpr.JPR_D_25_00308","DOIUrl":"https://doi.org/10.2186/jpr.JPR_D_25_00308","url":null,"abstract":"<p><strong>Purpose: </strong>We evaluated the influence of multiple uses of scan bodies after reprocessing cycles-steam sterilization and thermal disinfection-on the precision of implant position transfer.</p><p><strong>Methods: </strong>Six mandibular models with two implants in regions 34 and 36 were fabricated. The implants were scanned with an intraoral scanner using pairs of titanium (SB_T_Pr) and polyether ether ketone (PEEK) (SB_P_Pr) scan bodies according to the manufacturers' recommendations. The scan body group underwent up to 15 standardized reprocessing cycles. The unreprocessed titanium group (SB_T_NPr) served as a control. Three-dimensional deviations (R) between the implant positions were calculated from the scanned STL datasets and statistically analyzed (P < 0.05).</p><p><strong>Results: </strong>A preliminary investigation demonstrated that 15 cycles of screwing in and out of the titanium or PEEK scan bodies did not influence subsequent measurements (P = 0.129, P = 0.215). The mean ΔR values were 38.9 ± 18.7 µm for SB_T_NPr and 42.6 ± 19.5 µm for SB_T_Pr. No significant differences in precision were found between the unprocessed and reprocessed titanium scan bodies within 15 cycles (P = 0.174). The mean ΔR value for SB_P_Pr was 27.1 ± 12.5 µm. In contrast, the PEEK scan bodies consistently showed significantly lower deviations than the titanium scan bodies (P < 0.001).</p><p><strong>Conclusions: </strong>PEEK scan bodies demonstrate higher precision but may be limited by lower mechanical stability and their single-use concept. Titanium scan bodies, although slightly less precise, have proven to be mechanically robust and suitable for multiple reuses after the conducted reprocessing. Further clinical studies with extended re-processing cycles are required to confirm these findings.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-driven innovations for dental implant treatment planning: A systematic review.","authors":"Kyaw Zaww, Hazem Abbas, Juan Ramón Vanegas Sáenz, Guang Hong","doi":"10.2186/jpr.JPR_D_24_00338","DOIUrl":"10.2186/jpr.JPR_D_24_00338","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review evaluates the effectiveness of artificial intelligence (AI) models in dental implant treatment planning, focusing on: 1) identification, detection, and segmentation of anatomical structures; 2) technical assistance during treatment planning; and 3) additional relevant applications.</p><p><strong>Study selection: </strong>A literature search of PubMed/MEDLINE, Scopus, and Web of Science was conducted for studies published in English until July 31, 2024. The included studies explored AI applications in implant treatment planning, excluding expert opinions, guidelines, and protocols. Three reviewers independently assessed study quality using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Quasi-Experimental Studies, resolving disagreements by consensus.</p><p><strong>Results: </strong>Of the 28 included studies, four were high, four were medium, and 20 were low quality according to the JBI scale. Eighteen studies on anatomical segmentation have demonstrated AI models with accuracy rates ranging from 66.4% to 99.1%. Eight studies examined AI's role in technical assistance for surgical planning, demonstrating its potential in predicting jawbone mineral density, optimizing drilling protocols, and classifying plans for maxillary sinus augmentation. One study indicated a learning curve for AI in implant planning, recommending at least 50 images for over 70% predictive accuracy. Another study reported 83% accuracy in localizing stent markers for implant sites, suggesting additional imaging planes to address a 17% miss rate and 2.8% false positives.</p><p><strong>Conclusions: </strong>AI models exhibit potential for automating dental implant planning with high accuracy in anatomical segmentation and insightful technical assistance. However, further well-designed studies with standardized evaluation parameters are required for pragmatic integration into clinical settings.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"192-205"},"PeriodicalIF":3.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cleaning methods of contaminated lithium disilicate ceramics: A systematic review and network meta-analysis.","authors":"Wichachon Thongkaemkaew, Putsadeeporn Thammajaruk, Massimiliano Guazzato","doi":"10.2186/jpr.JPR_D_24_00344","DOIUrl":"10.2186/jpr.JPR_D_24_00344","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects of various cleaning methods on the bond strength between lithium disilicate (LS₂) ceramics and resin cement under short- and long-term aging conditions using network meta-analysis (NMA) and pairwise meta-analysis (PMA).</p><p><strong>Study selection: </strong>An electronic search of seven databases (PubMed, Scopus, Embase, Web of Science, Google Scholar, Defense Technical Information Center, and LILACS) with a manual search of the reference lists was conducted for articles published up to March 10, 2025. Eligible studies included those that assessed the bond strength of LS₂, either uncontaminated or contaminated with human saliva, fit-checking materials, try-in paste, or their combinations, using different cleaning methods. Risk of bias was evaluated using the RoBDEMAT tool. A frequentist multivariable random-effects model was used to calculate the effect sizes.</p><p><strong>Results: </strong>Fifteen studies met the inclusion criteria. Under short-term aging conditions, NMA showed higher bond strengths in the uncontaminated LS₂ group and the contaminated groups cleaned with hydrofluoric acid etching, commercial ceramic cleaning agents, or phosphoric acid etching than those uncleaned or cleaned with water or alcohol. In long-term aging, PMA and NMA exhibited higher bond strengths in the uncontaminated LS₂ group and contaminated group cleaned with phosphoric acid etching than those contaminated groups cleaned with water or alcohol.</p><p><strong>Conclusions: </strong>Phosphoric acid etching effectively eliminates contaminants, whereas the application of water or alcohol is ineffective. Although ceramic cleaning agents effectively decontaminate surfaces under short-term aging conditions, their performance deteriorates over time, potentially compromising long-term bond durability.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"183-191"},"PeriodicalIF":3.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of open-hollow obturators with various bulb wall thicknesses and build angle fabricated using digital light processing.","authors":"Yuka Sasaki, Yutaro Oyamada, Atsuo Nakanishi, Ryota Sakai, Noriaki Takahashi, Kazuhiro Kon","doi":"10.2186/jpr.JPR_D_25_00020","DOIUrl":"10.2186/jpr.JPR_D_25_00020","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate and compare the effect of bulb wall thickness and build angle on the trueness and weight of an open-hollow obturator fabricated using digital light processing (DLP) technology.</p><p><strong>Methods: </strong>A 3D model of an edentulous maxillary jaw with an Aramany Class I defect was designed using computer-aided design (CAD) software, and 45 obturators with bulb wall thicknesses of 1, 2, and 3 mm were fabricated using a DLP printer at build angles of 0, 45, and 315 degrees, respectively. The weight of each obturator was measured. All obturators were scanned using cone-beam computed tomography, and the data were converted to the standard tessellation language format. The CAD and scanning data were superimposed for inspection. Statistical analysis was performed using two-way analysis of variance (ANOVA) and Tukey's test.</p><p><strong>Results: </strong>The two-way ANOVA showed a significant effect of the build angle on the denture base (P < 0.001); however, the bulb wall thickness had no significant effect (P = 0.73). Both the bulb wall thickness and build angle significantly affected the inner and outer bulb surfaces (P < 0.001), and a significant interaction between these factors was observed (P < 0.05). Significant differences were observed between bulbs (P < 0.001). Additionally, weight was significantly affected by both factors and their interactions (P < 0.001).</p><p><strong>Conclusions: </strong>The bulb wall thickness and build angle significantly influenced the trueness and weight of the open-hollow DLP obturator, with the least error observed at a zero-degree build angle.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"297-305"},"PeriodicalIF":3.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of intaglio surface depth and scanning technology on the trueness of complete denture scans using intraoral scanners.","authors":"Yuanhua Piao, Maiko Iwaki, Yumi Tsuchida, Yo Akiyama, Wenming Zhou, Atsushi Takaichi, Manabu Kanazawa","doi":"10.2186/jpr.JPR_D_25_00067","DOIUrl":"10.2186/jpr.JPR_D_25_00067","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate how the depth of the intaglio surface on the denture and the scanning method influence the trueness using two types of intraoral scanners (IOS) for complete dentures.</p><p><strong>Methods: </strong>Four complete denture types (Extra-deep, Deep, Moderate, Shallow) with varying intaglio surface depths (Extra-deep > Deep > Moderate > Shallow) for the maxilla and mandible were designed using two computer-aided design software, resulting in 8 denture models. Reference data were obtained using a laboratory scanner (D2000). Each denture was scanned eight times using two IOSs: a confocal microscopy-based scanner (Trios 5) and a dual-triangulation-based scanner (i700), resulting in 64 scans per IOS (128 scans in total). Scan data were superimposed using three-dimensional editing software, and the root mean square (RMS) was calculated to assess trueness. Statistical analyses included the Shapiro-Wilk test for normality and two-way analysis of variance with Bonferroni correction (α=0.05).</p><p><strong>Results: </strong>For Trios 5, the RMS value for the Extra-deep was significantly higher than that for the Moderate and Shallow in both the maxilla and mandible. Furthermore, the Deep showed significantly higher RMS values than the Shallow in the maxilla. For i700, the RMS values did not significantly differ among the denture types. Across all denture types, the RMS values for i700 were significantly higher than those for Trios 5.</p><p><strong>Conclusions: </strong>The depth of the intaglio surface on the denture influenced trueness when using the Trios 5. The Trios 5 showed higher trueness than the i700 did across all denture types.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"306-312"},"PeriodicalIF":3.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145185859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing implant accuracy by guiding immediate placement with favorably aligned anterior maxillary roots.","authors":"Xiaowen Hu, Kayingkaren Chung","doi":"10.2186/jpr.JPR_D_25_00073","DOIUrl":"10.2186/jpr.JPR_D_25_00073","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the predictability of using the roots of the maxillary anterior teeth in advantageous positions to guide immediate implantation and enhance the positioning precision of placed implants.</p><p><strong>Methods: </strong>Existing root canals were used in the test group for manual preparation of the implant bed, whereas traditional freehand techniques were employed in the control group. The three-dimensional position of the placed implants was measured using radiological images taken on the day of surgery and again six months post-surgery and evaluated using self-developed rating criteria for the radiographic positions of the implants. The spatial relationship between the axial orientation of the implant and prosthetic crown was assessed using a self-developed scoring scale. Statistical analysis of the three-dimensional positional imaging scores of the implants was conducted immediately after surgery and at six months post-implantation. Intergroup statistical analysis was conducted on the scores reflecting the spatial relationship between the axial orientation of the implants and their prostheses.</p><p><strong>Results: </strong>The test group demonstrated significantly higher scores for the labial-palate and horizontal positions, both immediately following surgery and at six months post-implantation, than the control group. Furthermore, the test group significantly outperformed the control group in terms of scores reflecting spatial relationships.</p><p><strong>Conclusions: </strong>Utilizing the roots of the anterior teeth in advantageous positions as guides for preparing implant beds can lead to more ideal implant placement than traditional manual techniques.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"268-280"},"PeriodicalIF":3.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of titanium-base and universal abutment heights on the adaptation and fracture of screw-and-cemented-retained lithium disilicate crowns.","authors":"Aline Cristina de Oliveira, Henrico Badaoui Strazzi-Sahyon, Ana Teresa Maluly-Proni, Ana Luiza de Marchi, Wirley Gonçalves Assunção, Paulo Henrique Dos Santos, Rogério Margonar","doi":"10.2186/jpr.JPR_D_25_00065","DOIUrl":"10.2186/jpr.JPR_D_25_00065","url":null,"abstract":"<p><strong>Purpose: </strong>This in vitro study evaluated the adaptation and fracture resistance of screw- and cement-retained implant-supported restorations using lithium disilicate crowns cemented onto titanium bases and universal abutments of different heights.</p><p><strong>Methods: </strong>Thirty crowns were designed, milled, and divided into three groups: TBA (titanium base abutment - 4.7-mm-height and 4.65-mm-diameter), UA-4 (universal abutment - 4.0-mm-height and 4.5-mm-diameter), and UA-6 (universal abutment - 6.0-mm-height and 4.5-mm-diameter) (n=10). The abutments were placed in a mandibular first premolar model, torqued to 20 Ncm, and scanned using a digital intraoral scanner. The crowns were designed and fabricated using computer-aided design/computer-aided manufacturing technology. Adaptation was assessed using a stereomicroscope before and after ceramic sintering and after cementation with RelyX Ultimate resin cement. Fracture resistance was evaluated using a universal testing machine, and the failure modes were analyzed. The collected data were subjected to statistical analysis using one-way ANOVA and the Tukey least significant difference test (α=0.05).</p><p><strong>Results: </strong>The abutment type influenced restoration adaptation and fracture resistance. No differences in adaptation were found before or after luting (P > 0.05). However, after sintering, the TBA group exhibited smaller marginal gaps than the UA-4 (P = 0.0339) and UA-6 (P = 0.0006) groups. TBA showed a higher fracture resistance than UA-4 (P = 0.0093); no differences were observed between TBA and UA-6 or between UA-4 and UA-6 (P > 0.05). The UA-4 and UA-6 groups showed higher ceramic fracture rates, whereas the TBA group showed increased abutment deformation and ceramic fractures.</p><p><strong>Conclusions: </strong>The type and height of abutments influenced the fracture of screw-and-cement-retained implant-supported restorations.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"259-267"},"PeriodicalIF":3.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flexural strength of translucent zirconia for single crowns and fixed dental prostheses-A systematic review.","authors":"Selina A Bernauer, Nicola M Lirgg, Alexis Ioannidis, Nicola U Zitzmann, Nadja Rohr","doi":"10.2186/jpr.JPR_D_24_00277","DOIUrl":"10.2186/jpr.JPR_D_24_00277","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this systematic review was to analyze the reported flexural strength values of commercially available translucent zirconia materials. Additionally, data were evaluated to assess the impact of different specimen preparations and test methods.</p><p><strong>Study selection: </strong>This systematic review was conducted according to the PRISMA guidelines. Electronic searches were performed to identify in vitro studies published between January 1, 2013, and March 15, 2025, that reported flexural strength values of translucent zirconia and included the names of the tested materials and manufacturers. Flexural strength values were analyzed to assess the effects of yttria content, specimen processing, surface treatments, and test methods using Kruskal-Wallis analysis of variance (α = 0.05) and forest plots.</p><p><strong>Results: </strong>A total of 78 laboratory studies met the inclusion criteria. The overall flexural strength values were significantly higher for 4Y-PSZ (803± 233 MPa) than for 5Y-PSZ materials (570 ± 116 MPa) (P = 0.005). Specimen processing, surface treatments, and test methods significantly affected the flexural strength values for 5Y-PSZ (P < 0.001) but not for 4Y-PSZ (P > 0.05).</p><p><strong>Conclusions: </strong>This systematic review highlights the challenges in comparing the flexural strength values of translucent zirconia owing to differences in processing parameters. Further standardization of test methods and adherence to ISO 6872 would improve comparability. Our findings support the clinical use of 4Y-PSZ for three-unit fixed dental prostheses (FDPs) and 5Y-PSZ for three-unit FDPs in the anterior region based on ISO 6872.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"173-182"},"PeriodicalIF":3.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}