Journal of prosthodontic research最新文献

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Proposals and evaluations for the enhancement of CAD/CAM education. 关于加强 CAD/CAM 教育的建议和评估。
IF 3.2 2区 医学
Journal of prosthodontic research Pub Date : 2024-10-24 DOI: 10.2186/jpr.JPR_D_24_00132
Maki Hosoki, Mayu Miyagi, Kazuo Okura, Miho Inoue, Masamitsu Oshima, Yoshitaka Suzuki, Aya Ozawa, Akari Shibagaki, Tatsuya Taniwaki, Kohei Kamoi, Nobuyuki Bando, Yasutomo Yoshihara, Mizuki Shinkai, Toyoko Tajima, Jaime Jr Fabillar, Yoshizo Matsuka
{"title":"Proposals and evaluations for the enhancement of CAD/CAM education.","authors":"Maki Hosoki, Mayu Miyagi, Kazuo Okura, Miho Inoue, Masamitsu Oshima, Yoshitaka Suzuki, Aya Ozawa, Akari Shibagaki, Tatsuya Taniwaki, Kohei Kamoi, Nobuyuki Bando, Yasutomo Yoshihara, Mizuki Shinkai, Toyoko Tajima, Jaime Jr Fabillar, Yoshizo Matsuka","doi":"10.2186/jpr.JPR_D_24_00132","DOIUrl":"https://doi.org/10.2186/jpr.JPR_D_24_00132","url":null,"abstract":"","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dental prosthesis use moderates association between tooth loss and risk of depressive symptoms in older adults with severe tooth loss: The JAGES cohort trial. 在牙齿严重缺失的老年人中,义齿的使用可缓和牙齿缺失与抑郁症状风险之间的关系:JAGES队列试验。
IF 3.2 2区 医学
Journal of prosthodontic research Pub Date : 2024-10-16 Epub Date: 2024-03-13 DOI: 10.2186/jpr.JPR_D_23_00046
Noriko Nakazawa, Kenji Takeuchi, Taro Kusama, Sakura Kiuchi, Katsunori Kondo, Ken Osaka
{"title":"Dental prosthesis use moderates association between tooth loss and risk of depressive symptoms in older adults with severe tooth loss: The JAGES cohort trial.","authors":"Noriko Nakazawa, Kenji Takeuchi, Taro Kusama, Sakura Kiuchi, Katsunori Kondo, Ken Osaka","doi":"10.2186/jpr.JPR_D_23_00046","DOIUrl":"10.2186/jpr.JPR_D_23_00046","url":null,"abstract":"<p><strong>Purpose: </strong>Depression is a leading cause of disability. Although tooth loss increases the risk of depressive symptoms, it is unclear whether dental prosthesis use moderates this risk. This study aimed to investigate whether dental prosthesis use moderates the association between tooth loss and new depressive symptoms in older adults.</p><p><strong>Methods: </strong>This cohort study used data from the 2016 and 2019 Japan Gerontological Evaluation Study (JAGES). The participants were independent older adults aged ≥65 years without depressive symptoms in 2016. The onset of depressive symptoms in 2019 was the outcome variable. The exposure variables were dental status (≥20 teeth, 10-19 teeth with or without dental prostheses, and 0-9 teeth with or without dental prostheses) in 2016. Risk ratios (RRs) and 95% confidence intervals (CIs) were estimated using Poisson regression models with potential confounders as covariates.</p><p><strong>Results: </strong>The analysis included 50,169 participants (mean age: 72.8 [standard deviation, 5.4] years). During follow-up, the incidence of depressive symptoms was 11.3%. Compared to those who had ≥20 teeth, the RR of depressive symptom onset was highest among those who had 0-9 teeth without dental prostheses (RR, 1.27; 95% CI, 1.04-1.56), after the adjustment for confounders. However, this risk was lower in those with 0-9 teeth and dental prostheses (RR, 1.08; 95% CI, 1.01-1.15).</p><p><strong>Conclusions: </strong>These data highlight the potential of dental prostheses as an important factor in reducing the risk of depressive symptoms among individuals with severe tooth loss.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"578-584"},"PeriodicalIF":3.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140119902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monolithic hybrid abutment crowns: Influence of crown height, crown morphology and material on the implant-abutment complex. 整体混合基台冠:牙冠高度、牙冠形态和材料对种植体-基台复合体的影响。
IF 3.2 2区 医学
Journal of prosthodontic research Pub Date : 2024-10-16 Epub Date: 2024-03-13 DOI: 10.2186/jpr.JPR_D_23_00253
Tobias Graf, Elisabeth Völler, Kurt Erdelt, Michael Stimmelmayr, Oliver Schubert, Jan-Frederik Güth
{"title":"Monolithic hybrid abutment crowns: Influence of crown height, crown morphology and material on the implant-abutment complex.","authors":"Tobias Graf, Elisabeth Völler, Kurt Erdelt, Michael Stimmelmayr, Oliver Schubert, Jan-Frederik Güth","doi":"10.2186/jpr.JPR_D_23_00253","DOIUrl":"10.2186/jpr.JPR_D_23_00253","url":null,"abstract":"<p><strong>Purpose: </strong>This in vitro study investigated the influence of material selection, crown morphology, and vertical crown height on the biomechanical behavior of screw-retained monolithic hybrid abutment crowns (HACs).</p><p><strong>Methods: </strong>Ninety implants were embedded in accordance with ISO standard 14801; ninety HACs were mounted (N=90). Monolithic crowns with varying group-specific designs were luted using titanium bases. HACs were fabricated from monolithic lithium disilicate ceramic (LD) or zirconia-reinforced lithium silicate ceramic (ZLS). The crown morphology was either maxillary premolar (LD_PM, ZLS_PM) or molar (LD_MO). The three groups were further divided into three subgroups of ten specimens, each designed with a small (7.5 mm), middle (10.5 mm), and high (13.5 mm) configuration of crown heights (N=10). A load-to-failure test at 30° off-axis was conducted using a universal testing machine until failure. For statistical analysis, Kolmogorov-Smirnov and Mann-Whitney U tests were conducted (P < 0.05).</p><p><strong>Results: </strong>All LD_MO groups presented the highest failure values (808.7 to 947.9 N), followed by the LD_PM (525.8 to 722.8 N) and ZLS_PM groups (312.6 to 478.8N). A comparison between LD and ZLS materials (P < 0.001) as well as the crown morphology (P < 0.001) showed significant differences in failure values. The values in the subgroups of ZLS_PM (low, middle, high) decreased as the crown height increased. The fracture modes showed no consistent patterns across the test groups.</p><p><strong>Conclusions: </strong>Material selection, crown morphology, and vertical crown height appear to be important factors that may influence the clinical failure values and patterns of screw-retained single implant crowns.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"606-614"},"PeriodicalIF":3.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140119904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does maintaining the number of present and functional teeth benefit the longevity of life in older people requiring nursing care?: A prospective cohort study. 保持牙齿的数量和功能是否有利于需要护理的老年人的长寿?一项前瞻性队列研究。
IF 3.2 2区 医学
Journal of prosthodontic research Pub Date : 2024-10-16 Epub Date: 2024-03-13 DOI: 10.2186/jpr.JPR_D_23_00221
Eri Koyama, Aya Kimura-Ono, Takuya Mino, Yoko Kurosaki, Kana Tokumoto, Michiyo Yamamoto, Shinsuke Nakagawa, Suguru Osaka, Kumiko Nawachi, Mami Inoue-Minakuchi, Mitsuaki Ono, Hajime Minakuchi, Kenji Maekawa, Takuo Kuboki
{"title":"Does maintaining the number of present and functional teeth benefit the longevity of life in older people requiring nursing care?: A prospective cohort study.","authors":"Eri Koyama, Aya Kimura-Ono, Takuya Mino, Yoko Kurosaki, Kana Tokumoto, Michiyo Yamamoto, Shinsuke Nakagawa, Suguru Osaka, Kumiko Nawachi, Mami Inoue-Minakuchi, Mitsuaki Ono, Hajime Minakuchi, Kenji Maekawa, Takuo Kuboki","doi":"10.2186/jpr.JPR_D_23_00221","DOIUrl":"10.2186/jpr.JPR_D_23_00221","url":null,"abstract":"<p><strong>Purpose: </strong>This prospective cohort study examined the effects of the number of present and functional teeth on mortality among older Japanese adults requiring nursing care in an environment of comprehensive oral hygiene and nutritional management.</p><p><strong>Methods: </strong>The study included 174 older adults (mean age: 84.4 ± 8.3 years; male/female: 49/125) in need of support or long-term care, who resided in either a local specialized healthcare facility or their own homes, and received daily oral hygiene and nutritional support at facilities in Okayama, Japan. The initial clinical oral examination along with assessment of general physical condition and nursing environment of the participants were performed in July 2013 and followed up for one year.</p><p><strong>Results: </strong>All-cause mortality occurred in 28 (mean age: 88.7 ±13.4 years; male/female: 6 /22) individuals during the follow-up period. Cox proportional hazard analysis indicated that older age, low performance in activities of daily living (Barthel Index <40), and underweight status (body mass index <18.5) were significant risk factors for mortality. The number of present and functional teeth were not found to be significant risk factors for mortality.</p><p><strong>Conclusions: </strong>During the one-year follow-up period, the number of present and functional teeth did not have a significant impact on mortality among older Japanese adults requiring nursing care in a well-managed environment of oral hygiene and nutritional status.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"599-605"},"PeriodicalIF":3.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140119903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A dual composite resin injection molding technique with 3D-printed flexible indices for biomimetic replacement of a missing mandibular lateral incisor. 双复合树脂注射成型技术与三维打印柔性指数用于下颌侧切牙缺失的仿生替代。
IF 3.2 2区 医学
Journal of prosthodontic research Pub Date : 2024-10-16 Epub Date: 2024-03-13 DOI: 10.2186/jpr.JPR_D_23_00239
Keiichiro Watanabe, Eiji Tanaka, Kohei Kamoi, Antonin Tichy, Takahiko Shiba, Kazuhide Yonerakura, Masatoshi Nakajima, Ruonan Han, Keiichi Hosaka
{"title":"A dual composite resin injection molding technique with 3D-printed flexible indices for biomimetic replacement of a missing mandibular lateral incisor.","authors":"Keiichiro Watanabe, Eiji Tanaka, Kohei Kamoi, Antonin Tichy, Takahiko Shiba, Kazuhide Yonerakura, Masatoshi Nakajima, Ruonan Han, Keiichi Hosaka","doi":"10.2186/jpr.JPR_D_23_00239","DOIUrl":"10.2186/jpr.JPR_D_23_00239","url":null,"abstract":"<p><strong>Patients: </strong>This case report presents a minimally invasive approach to replace a missing mandibular lateral incisor using a dual-injection molding technique with flowable composite resins. Integrated with a comprehensive digital workflow, this method achieves a structurally and esthetically biomimetic, bi-layered prosthetic solution. A 34-year-old woman with congenital absence of a mandibular lateral incisor was successfully rehabilitated using a direct composite resin-bonded fixed partial denture (RBFPD).</p><p><strong>Discussion: </strong>Two specialized three-dimensional (3D)-printed flexible indices stabilized by a custom-designed 3D-printed rigid holder were employed to ensure the meticulous injection molding of flowable composite resins formulated to emulate the inherent chromatic gradations between dentin and enamel. The inherent flexibility of the indices, combined with the holder, facilitated accurate and seamless adaptation to the complex morphological features of the dental arch, thereby mitigating the challenges commonly associated with rigid 3D-printed resin indices.</p><p><strong>Conclusions: </strong>The bilayered direct composite RBFPD using 3D printed flexible indices prepared with a full digital workflow has several advantages over other dental prosthetic solutions, including noninvasiveness, cost-effectiveness, biomimetic esthetics, repairability, and shortened treatment times. Although the initial results are promising, further longitudinal studies with larger patient cohorts are required to confirm the long-term efficacy of this approach.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"667-671"},"PeriodicalIF":3.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140119892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dietary inflammatory index and number of functional teeth in middle-aged and older Japanese adults: A cross-sectional study using national survey data. 日本中老年人的膳食炎症指数和功能性牙齿数量:一项利用全国调查数据进行的横断面研究。
IF 3.2 2区 医学
Journal of prosthodontic research Pub Date : 2024-10-16 Epub Date: 2024-03-27 DOI: 10.2186/jpr.JPR_D_23_00269
Masanori Iwasaki, Misuzu Sato, Dairo Takahashi, Takafumi Yamamoto
{"title":"Dietary inflammatory index and number of functional teeth in middle-aged and older Japanese adults: A cross-sectional study using national survey data.","authors":"Masanori Iwasaki, Misuzu Sato, Dairo Takahashi, Takafumi Yamamoto","doi":"10.2186/jpr.JPR_D_23_00269","DOIUrl":"10.2186/jpr.JPR_D_23_00269","url":null,"abstract":"<p><strong>Purpose: </strong>To determine whether the number of functional teeth, including the remaining natural teeth and prosthetically restored missing teeth, is associated with the dietary inflammatory index (DII), a quantitative measure of the inflammatory potential of the overall diet, in middle-aged and older Japanese adults.</p><p><strong>Methods: </strong>National survey data from a non-institutionalized Japanese population aged ≥45 years was analyzed. Multivariable linear regression analyses were performed to assess the association between the DII score, which was calculated based on dietary records, and the number of functional teeth, which was determined during dental examination. All regression analyses were stratified according to the age groups 45-64, 65-74, and ≥75 years. The association between functional tooth units (FTUs) and the DII was assessed using sensitivity analysis.</p><p><strong>Results: </strong>In total, 2407 individuals (1053 men and 1354 women; mean age = 66.7 years) were included. Multivariable analysis revealed that the number of functional teeth was significantly inversely associated with the DII score among participants aged ≥75 years (regression coefficient per increase of one in the number of functional teeth = -0.050; 95% confidence interval = -0.089 to -0.010). The number of functional teeth was not associated with the DII score in younger age categories (i.e., those aged 45-74 years). As in the primary analysis, the number of FTUs was significantly inversely associated with the DII score only in the group aged ≥75 years.</p><p><strong>Conclusions: </strong>A greater number of functional teeth was associated with a lower DII (i.e., diet with greater anti-inflammatory potential) in Japanese adults aged ≥75 years.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"643-649"},"PeriodicalIF":3.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140306021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of different palatal morphologies on the accuracy of intraoral scanning of the edentulous maxilla: A three-dimensional analysis. 不同腭部形态对无牙上颌骨口内扫描准确性的影响:三维分析。
IF 3.2 2区 医学
Journal of prosthodontic research Pub Date : 2024-10-16 Epub Date: 2024-06-12 DOI: 10.2186/jpr.JPR_D_23_00175
Roberto Sorrentino, Gennaro Ruggiero, Renato Leone, Maria Irene Di Mauro, Edoardo Ferrari Cagidiaco, Tim Joda, Lucio Lo Russo, Fernando Zarone
{"title":"Influence of different palatal morphologies on the accuracy of intraoral scanning of the edentulous maxilla: A three-dimensional analysis.","authors":"Roberto Sorrentino, Gennaro Ruggiero, Renato Leone, Maria Irene Di Mauro, Edoardo Ferrari Cagidiaco, Tim Joda, Lucio Lo Russo, Fernando Zarone","doi":"10.2186/jpr.JPR_D_23_00175","DOIUrl":"10.2186/jpr.JPR_D_23_00175","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the influence of different palatal morphologies on the accuracy of intraoral scanning (TRIOS 4) of edentulous maxillae.</p><p><strong>Methods: </strong>Six typodonts were fabricated for different palatal morphologies with flat (F), medium (M), and deep (D) palates, with palatal wrinkles (W), or smooth palates (S), resulting in six groups: WF, WM, WD and SF, SM, SD. Ten scans were performed for each group; standard tessellation language files obtained were imported into a software to measure trueness and precision in micrometer. Trueness was calculated as the mean of the standard deviation values obtained by superimposing each scan onto the reference scan. Precision was achieved by overlapping each scan with that with the best trueness in the group. Descriptive and post-hoc analyses were conducted.</p><p><strong>Results: </strong>The mean values for trueness were as follows: WM=48.7±4.7, WD=161.7±18.4, WF=85.9±16, SM=48.1±2.4, SD=349.9±8.8, and SF=349.1±25.5. The precision values were as follows: WM=46.7±7.3, WD=46.9±9, WF=48.9±6.7, SM=46±2.7, SD=105.9±17.4, SF=72.6±10.8. Significant differences were observed for trueness between SM and SD (P < 0.001), SM and SF (P < 0.001), and WF and SF (P = 0.003); whereas for precision, significant differences were reported between WD and SD (P = 0.015). Regarding trueness and precision, no difference was found between WM and SM (P = 1.0).</p><p><strong>Conclusions: </strong>Medium palatal depth showed the best accuracy. The mean accuracy values were within the clinical acceptability thresholds for all palatal morphologies. The presence of rugae improved the precision of deeper palates and the trueness of flat palates. No differences were observed in the medium palates with or without rugae.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"634-642"},"PeriodicalIF":3.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141310863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Partial fixed dental prostheses fabricated using fiber-reinforced composite resin supported by short and extra-short implants: A case series. 使用纤维增强复合树脂制作的部分固定义齿,由短种植体和超短种植体支撑:病例系列。
IF 3.2 2区 医学
Journal of prosthodontic research Pub Date : 2024-10-16 Epub Date: 2024-06-26 DOI: 10.2186/jpr.JPR_D_23_00005
Yu-Chi Cheng, Estevam A Bonfante, Edmara T P Bergamo, Rolf Ewers
{"title":"Partial fixed dental prostheses fabricated using fiber-reinforced composite resin supported by short and extra-short implants: A case series.","authors":"Yu-Chi Cheng, Estevam A Bonfante, Edmara T P Bergamo, Rolf Ewers","doi":"10.2186/jpr.JPR_D_23_00005","DOIUrl":"10.2186/jpr.JPR_D_23_00005","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the 10-year outcomes of partial fixed dental prostheses (P-FDPs) fabricated using metal-free fiber-reinforced composite (FRC) resin frameworks veneered with composite resin and supported by short and extra-short implants.</p><p><strong>Methods: </strong>This study included 28 patients with 38 FRC prostheses supported by 96 implants. Implant and prosthesis survival and success rates were evaluated using Kaplan-Meier analysis.</p><p><strong>Results: </strong>The 10-year implant survival and success rate, as determined by Kaplan-Meier analysis, was 96.9%, and the prosthesis survival and success rates were 94.7% and 92.0%, respectively. None of the parameters under investigation were significantly correlated with prosthetic survival or successful outcomes, but three parameters were correlated with higher peri-implant bone levels: implant placement in the mandible as opposed to the maxilla, shorter P-FDP spans, and natural teeth on the opposing arch.</p><p><strong>Conclusions: </strong>FRC P-FDPs supported by short and extra-short implants presented high, up to 10-year, survival and success rates, when used to restore partially edentulous arches.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"624-633"},"PeriodicalIF":3.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141457633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innate immune regulation in dental implant osseointegration. 牙科种植体骨结合中的先天免疫调节。
IF 3.2 2区 医学
Journal of prosthodontic research Pub Date : 2024-10-16 Epub Date: 2024-02-16 DOI: 10.2186/jpr.JPR_D_23_00198
Takeru Kondo, Masahiro Yamada, Hiroshi Egusa
{"title":"Innate immune regulation in dental implant osseointegration.","authors":"Takeru Kondo, Masahiro Yamada, Hiroshi Egusa","doi":"10.2186/jpr.JPR_D_23_00198","DOIUrl":"10.2186/jpr.JPR_D_23_00198","url":null,"abstract":"<p><strong>Purpose: </strong>Dental implant osseointegration comprises two types of bone formation-contact and distance osteogenesis-which result in bone formation originating from the implant surface or bone edges, respectively. The physicochemical properties of the implant surface regulate initial contact osteogenesis by directly tuning the osteoprogenitor cells in the peri-implant environment. However, whether these implant surface properties can regulate osteoprogenitor cells distant from the implant remains unclear. Innate immune cells, including neutrophils and macrophages, govern bone metabolism, suggesting their involvement in osseointegration and distance osteogenesis. This narrative review discusses the role of innate immunity in osseointegration and the effects of implant surface properties on distant osteogenesis, focusing on innate immune regulation.</p><p><strong>Study selection: </strong>The role of innate immunity in bone formation and the effects of implant surface properties on innate immune function were reviewed based on clinical, animal, and in vitro studies.</p><p><strong>Results: </strong>Neutrophils and macrophages are responsible for bone formation during osseointegration, via inflammatory mediators. The microroughness and hydrophilic status of titanium implants have the potential to alleviate this inflammatory response of neutrophils, and induce an anti-inflammatory response in macrophages, to tune both contact and distance osteogenesis through the activation of osteoblasts. Thus, the surface micro-roughness and hydrophilicity of implants can regulate the function of distant osteoprogenitor cells through innate immune cells.</p><p><strong>Conclusions: </strong>Surface modification of implants aimed at regulating innate immunity may be useful in promoting further osteogenesis and overcoming the limitations encountered in severe situations, such as early loading protocol application.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"511-521"},"PeriodicalIF":3.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139723077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of ethylene oxide unit number in bis-EMA on the physical properties of additive-manufactured occlusal splint material. 双-EMA 中环氧乙烷单位数对添加剂制造的咬合夹板材料物理性能的影响。
IF 3.2 2区 医学
Journal of prosthodontic research Pub Date : 2024-10-16 Epub Date: 2024-01-29 DOI: 10.2186/jpr.JPR_D_23_00203
Junichiro Wada, Paulina Heponiemi, Kanae Wada, Sufyan Garoushi, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K Vallittu, Lippo Lassila
{"title":"Effect of ethylene oxide unit number in bis-EMA on the physical properties of additive-manufactured occlusal splint material.","authors":"Junichiro Wada, Paulina Heponiemi, Kanae Wada, Sufyan Garoushi, Noriyuki Wakabayashi, Tsutomu Iwamoto, Pekka K Vallittu, Lippo Lassila","doi":"10.2186/jpr.JPR_D_23_00203","DOIUrl":"10.2186/jpr.JPR_D_23_00203","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the effects of the number of ethylene oxide units in bis-EMA on the physical properties of additively manufactured occlusal splints.</p><p><strong>Methods: </strong>Seven experimental materials containing bis-EMAs with three and 10 ethylene oxide units (BE3 and BE10, respectively) were prepared at different BE10 content rates (BE10-0%, -20%, -30%, -40%, -50%, -60%, and -80%). Half the specimens of each material were aged in boiling water. Flexural strength (FS), flexural modulus (FM), fracture toughness (FT), microwear depth (MD), degree of conversion (DC), water sorption (WSP), water solubility (WSL), color difference between non-aged and aged series (ΔE), and translucency (TP) were evaluated. All the evaluated properties other than FS and MD were analyzed by 1-way ANOVA and Tukey's post hoc analysis, while FS and MD were analyzed by Kruskal-Wallis's test and Bonferroni correction (α=0.05).</p><p><strong>Results: </strong>BE10-80% revealed the lowest FS (P < 0.01 for BE10-0%, -20%, and -30%) and FM (P < 0.01, for all), while revealing the highest DC, WSP, WSL (P < 0.01 for all) and TP (P < 0.01 for all other than BE10-60%). BE10-50% showed the highest FT (P < 0.01 for all). BE10-50%, -60%, and -80% revealed significantly lower ΔE than others (P < 0.01) and lower MD than BE10-0% (P < 0.05). Regardless of the BE10 content, FS, FM, and FT decreased with aging.</p><p><strong>Conclusions: </strong>The number of ethylene oxide units affects the physical properties of additively manufactured occlusal splints. The higher number of ethylene oxide units in bis-EMA enhanced the microwear resistance, DC, WSP, WSL, color stability, and translucency, whereas it deteriorated the FS and FM.</p>","PeriodicalId":16887,"journal":{"name":"Journal of prosthodontic research","volume":" ","pages":"558-567"},"PeriodicalIF":3.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139570555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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