Journal of patient safety and quality improvement最新文献_第5页

Frequency of Registered Medical Errors in a Hospital in Ardabil, Iran, Within 2017-18 2017- 2018年伊朗阿达比尔一家医院的医疗差错登记频率

Journal of patient safety and quality improvement Pub Date : 2020-04-01 DOI: 10.22038/PSJ.2020.46962.1264

Maryam Faraji-Fard, F. Amani, S. Jeddi, N. Mobaraki, M. Yousefian

{"title":"Frequency of Registered Medical Errors in a Hospital in Ardabil, Iran, Within 2017-18","authors":"Maryam Faraji-Fard, F. Amani, S. Jeddi, N. Mobaraki, M. Yousefian","doi":"10.22038/PSJ.2020.46962.1264","DOIUrl":"https://doi.org/10.22038/PSJ.2020.46962.1264","url":null,"abstract":"Introduction: Patient safety is one of the main goals in a health system trying to reduce patient problems during hospitalization. These problems can be due to unintentional errors made by clinical staff the recognition and management of which are very important. The present study aimed to investigate the registered medical errors in Alavi hospital in Ardabil, Iran, during 2017-2018. Materials and Methods: In this cross-sectional study, all the wards were studied in Alavi hospital, and the data were collected by the evaluation of reported errors made by clinical staff and completion of the registered medical error forms. The collected data were analyzed through descriptive statistics. Results: During the study period, 1,050 registered errors were evaluated. Most errors (n=482; 45.9%) were detected in the women’s surgery ward. According to the number of errors made by nurses in the hospital in comparison to those reported for other clinical groups, the nurses with 464 cases (44%) had the highest frequency of medical errors, and the caring errors (29%) were the most frequently committed type of errors. Conclusion: Based on the obtained results of the current study, it was shown that caring errors were the most frequently committed errors, and the highest frequency of medical errors occurred in the women’s surgery ward. Therefore, providing educational training, emphasizing on doing hospital process, reducing the duration of work shifts, and increasing the number of personnel in hospitals, could be effective in decreasing errors and associated consequences.","PeriodicalId":16681,"journal":{"name":"Journal of patient safety and quality improvement","volume":"44 1","pages":"77-83"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84138601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Prevalence and Types of Medical Errors at a Trauma Center in Isfahan, Iran (2018-2019) 2018-2019年伊朗伊斯法罕创伤中心医疗差错发生率及类型分析

Journal of patient safety and quality improvement Pub Date : 2020-04-01 DOI: 10.22038/PSJ.2020.47570.1269

N. T. Chaharsoughi, M. N. Esfahani, Marzieh Sadat Sodoury

{"title":"Prevalence and Types of Medical Errors at a Trauma Center in Isfahan, Iran (2018-2019)","authors":"N. T. Chaharsoughi, M. N. Esfahani, Marzieh Sadat Sodoury","doi":"10.22038/PSJ.2020.47570.1269","DOIUrl":"https://doi.org/10.22038/PSJ.2020.47570.1269","url":null,"abstract":"Introduction Clinical errors can affect patient safety, reduce the quality of care, or even cause irreparable harm to the patients. Attention has been primarily tended to be directed toward medication errors; accordingly, limited focus has been placed on other clinical errors, such as caring, therapeutic, and blood transfusion errors. Regarding this, the present study was aimed to perform a comprehensive investigation of the type and prevalence of different clinical errors in a teaching trauma hospital. Materials and Methods This descriptive study was targeted toward the evaluation of the types and frequency of medical errors in the Trauma Center of Ayatollah Kashani Hospital in Isfahan, Iran, during 2018 and 2019. The data were collected using a clinical error reporting form, covering such data as the type of error, error severity, and associated ward. The data were analyzed in SPSS software, version 16. Results A total of 375 errors were reported, the majority of which were related to imaging and radiology domains (26.7%), followed by laboratory and blood bank (22.9%). In terms of job position, nurses (42.6%) and physicians (29.5%) made the majority of the errors. Furthermore, most of the errors occurred in the morning shifts (57.3%) and at the hospital emergency department (28.9%). Conclusion According to the results of the present study, the emergency department requires more attention to reduce the documentation errors of radiology and imaging.","PeriodicalId":16681,"journal":{"name":"Journal of patient safety and quality improvement","volume":"23 1","pages":"85-91"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83760027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Phaeohyphomycosis an Emerging Fungal Infection in Iran? A Short Communication 褐丝酵母菌病在伊朗是一种新出现的真菌感染吗?简短的交流

Journal of patient safety and quality improvement Pub Date : 2020-04-01 DOI: 10.22038/PSJ.2020.46271.1262

H. Zarrinfar, Chhavi Bathla

{"title":"Is Phaeohyphomycosis an Emerging Fungal Infection in Iran? A Short Communication","authors":"H. Zarrinfar, Chhavi Bathla","doi":"10.22038/PSJ.2020.46271.1262","DOIUrl":"https://doi.org/10.22038/PSJ.2020.46271.1262","url":null,"abstract":"Introduction: Phaeohyphomycosis is a rare opportunistic fungal infection that can be caused by dematiaceous fungi. The clinical manifestations of this disease are highly diverse and include cutaneous, subcutaneous, and systemic forms. However, the mortality rate of this infection depends on the immune status of patients. Although infections caused by black fungi have been on an increasing trend during the past decade, infections with dematiaceous fungi have rarely been reported in the Middle East. However, some fungal species are associated with a disseminated disease without the known clinical and pathologic risk factors. The analysis of DNA sequence is a highly effective method for differentiating various species among some genera, due to the variable cultural and morphological characteristics of DNA. Despite the presence of therapeutic methods, there are numerous reports regarding the high mortality rate of this infection. Published studies indicate no specific risk factors for phaeohyphomycosis and report the incidence of this disease in immunocompetent individuals. Moreover, selective treatment for these rare infections has not even been defined in clinical studies. However, the clinical syndromes associated with dematiaceous fungi should be considered in the Middle East, Iran.","PeriodicalId":16681,"journal":{"name":"Journal of patient safety and quality improvement","volume":"232 1","pages":"123-126"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87042934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modified Workload Indicators of Staffing Need to Estimate Human Resources at a Health Facility 估算卫生机构人力资源的人员配置需求的修正工作量指标

Journal of patient safety and quality improvement Pub Date : 2020-04-01 DOI: 10.22038/PSJ.2020.43932.1247

S. Tabatabaee

{"title":"Modified Workload Indicators of Staffing Need to Estimate Human Resources at a Health Facility","authors":"S. Tabatabaee","doi":"10.22038/PSJ.2020.43932.1247","DOIUrl":"https://doi.org/10.22038/PSJ.2020.43932.1247","url":null,"abstract":"Introduction: Human resources planning is known as the most essential limitation in achieving health care quality in the world. The main component of health human resource planning is to determine the required staff. There are several methods for determining required staff in a health facility. In this regard, one of the most widely used methods is the workload indicator of staffing need (WISN) method. In 1998, the World Health Organization announced the WISN as a human resource planning tool for the rational distribution of staff at health centers at all levels. It has been used in some countries since then. There is a recommendation on the division of the workload components. According to the modified workload indicator of staffing need (MWISN), there are four kinds of workload component. The first one is common main activity accomplished by all employees of the job category and for which periodic statistics are regularly collected. Uncommon main activity is the second one performed by a limited number of employees of the job category and for which periodic statistics are regularly collected. Moreover, support activities performed by all employees of the job category but for which periodic statistics are not regularly collected. The last one is additional activities performed only by some employees of the job category and for which periodic statistics are not regularly collected. Following the new division of the workload components, the final formula for the estimation of required workforce requirements is modified. Therefore, the MWISN can increase the accuracy and precision of the measurement of the workload and determine the number of workforces required.","PeriodicalId":16681,"journal":{"name":"Journal of patient safety and quality improvement","volume":"4 1","pages":"117-121"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84115560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Prescription Audit towards Quality Indicators at a Tertiary Care Teaching Hospital in South India 南印度一家三级护理教学医院的处方质量指标审计

Journal of patient safety and quality improvement Pub Date : 2020-04-01 DOI: 10.22038/PSJ.2020.45796.1260

A. Chakraborty, Mohammad Riyash, K. Srinivasan, V. Lakshmi

{"title":"Prescription Audit towards Quality Indicators at a Tertiary Care Teaching Hospital in South India","authors":"A. Chakraborty, Mohammad Riyash, K. Srinivasan, V. Lakshmi","doi":"10.22038/PSJ.2020.45796.1260","DOIUrl":"https://doi.org/10.22038/PSJ.2020.45796.1260","url":null,"abstract":"Introduction: The World Health Organization has laid down guidelines for rational prescriptions. Adherence to those guidelines is an important aspect of medication safety. In India, such adherence is mandatory towards National Accreditation Board for Hospitals and Health-care Providers (NABH) accreditation of health-care facilities. The audition of the prescriptions is therefore a quality improvement process that indirectly benefits the health-care stakeholders. Such an audit is part of the NABH Management of Medication and is monitored by the Pharmacy and Therapeutics (PT moreover, 97% (n=4656) and 47% (n=2256) of the prescriptions were legible and were written in generics, respectively. Furthermore, 97% (n=4656) of the orders had a physician’s signature, and 70% (3360) of them had a clinical review. It should be noted that only 1% (n=48) of the orders had drug-drug and drug-food documented interactions. Conclusion: According to the results of this study, physicians did not document suggestions regarding drug-drug and drug-food interactions. Moreover, there were fewer numbers of prescriptions written in generics. In addition, the majority of the medication orders were legible and adhered to standards in the 12th month. This may be due to sharing the monthly audit reports with various departments and the continuous feedback process involving the P&T committee.","PeriodicalId":16681,"journal":{"name":"Journal of patient safety and quality improvement","volume":"10 1","pages":"99-105"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81912769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of Nurse’s Characteristics on Their Willingness to Involve Patients in the Care Process in Hospitals in Tehran, Iran 伊朗德黑兰医院护士特质对患者参与护理意愿的影响

Journal of patient safety and quality improvement Pub Date : 2020-04-01 DOI: 10.22038/PSJ.2020.42788.1242

M. Amini, M. Mahmoudi, M. Jafari, M. Amini

{"title":"Effect of Nurse’s Characteristics on Their Willingness to Involve Patients in the Care Process in Hospitals in Tehran, Iran","authors":"M. Amini, M. Mahmoudi, M. Jafari, M. Amini","doi":"10.22038/PSJ.2020.42788.1242","DOIUrl":"https://doi.org/10.22038/PSJ.2020.42788.1242","url":null,"abstract":"Introduction: Patient involvement in the care process is a widespread concept, which is considered an important issue to improve the quality of healthcare. This study aimed at assessing the effect of nurses’ characteristics on their willingness to involve patients in the care process in hospitals in Tehran, Iran. Materials and Methods: This study utilized the patient participation culture tool for healthcare workers to measure patient participation behavior. The cross-sectional data were collected from randomly selected nurses who were working in 11 hospitals affiliated to Tehran University of Medical Sciences, Tehran, Iran. Furthermore, the data were analyzed using a linear mixed model to analyze the differences among the nurses’ characteristics. Moreover, the data were adjusted by the random effects of differences between hospitals and wards. A P-value less than 0.05 was considered statistically significant. Results: In total, 220 nurses from 18 wards participated in this study. The results showed that male nurses had a higher tendency to answer challenging questions (β=1.4; P=0.04), and younger nurses had significantly lower perceptions on coping with notifying questions asked by the patients (β=-1.7; P=0.02). In addition, nurses with Bachelor's degrees felt more support (β=2.8; P=0.02) and were more engaged in information sharing and dialogue (β=5.0; P=0.03). Furthermore, the full-time employed nurses perceived a lower lack of time (β=-1.2; P=0.002), compared to part-time peers. Conclusion: The findings indicate that the features and characteristics of the nurses might have an essential influence on patient involvement. Therefore, attention must be paid to these factors to overcome problems and obstacles that are encountered on the way of achieving effective patient involvement.","PeriodicalId":16681,"journal":{"name":"Journal of patient safety and quality improvement","volume":"24 1","pages":"107-115"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85967103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the Chest Radiograph Findings in Children with Pneumonia Hospitalized in a Children's Hospital, Tabriz, Iran 伊朗大不里士一家儿童医院肺炎患儿胸片表现的调查

Journal of patient safety and quality improvement Pub Date : 2020-04-01 DOI: 10.22038/PSJ.2020.46794.1263

Amirreza Jahanshahi, M. R. Farshi, Rojhin Saed Moocheshi, Zakieh Ebadi, B. Abdinia

{"title":"Investigation of the Chest Radiograph Findings in Children with Pneumonia Hospitalized in a Children's Hospital, Tabriz, Iran","authors":"Amirreza Jahanshahi, M. R. Farshi, Rojhin Saed Moocheshi, Zakieh Ebadi, B. Abdinia","doi":"10.22038/PSJ.2020.46794.1263","DOIUrl":"https://doi.org/10.22038/PSJ.2020.46794.1263","url":null,"abstract":"Introduction: Pneumonia has been regarded as the leading cause of death among the elderly, very young children, and those who suffer from chronic diseases. Among the underlying causes, viral infections have been addressed as the most frequent cause of pneumonia in children. Materials and Methods: This study investigated a total of 300 subjects with pneumonia hospitalized in Tabriz Children's Hospital, Tabriz, Iran. Moreover, a comparison was made between the type of pneumonia and associated radiologic features. Age, gender, performed laboratory tests, symptoms, and final interpretations of the chest x-ray (CXR) images were included in the checklist. Results: The mean age of the patients was 6.09 2.45 years. Moreover, the mean erythrocyte sedimentation rate was estimated at 27.86±22.73 mm/h. In this study, 174 (58%), 57 (19%), 50 (16.7%), and 19 (6.3%) patients were C-reactive protein (CRP) negative, CRP (+), CRP (++), and CRP (+++), respectively. Furthermore, in 238 (79.3%) patients, white blood cell (WBC) count in serum was within the normal range, whereas high WBC count was reported in 62 individuals (20.7%). In addition, four positive blood cultures as well as 27 (9%) cases with pleural effusion were identified in this study. Reticulonodular involvement was recognized in up to 246 (82%) subjects. It should be noted that 63 (21%) and 237 (79%) patients showed unilateral and bilateral involvement in chest radiography, respectively. Regarding the frequency of radiographic evidence, the most common patterns of involvement in descending frequencies were reticulonodular and lobar alveolar. Conclusion: The most common pattern of involvement in children's CXRs with pneumonia is a reticulonodular pattern associated with bilateral peribronchial cuffing.","PeriodicalId":16681,"journal":{"name":"Journal of patient safety and quality improvement","volume":"329 1","pages":"93-98"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76547564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Anesthesia Checklist: A Survey of Compliance and Attitudes 麻醉检查表:依从性和态度调查

Journal of patient safety and quality improvement Pub Date : 2020-04-01 DOI: 10.22038/PSJ.2020.48968.1275

Andrew O’Donoghue, S. Mannion

{"title":"An Anesthesia Checklist: A Survey of Compliance and Attitudes","authors":"Andrew O’Donoghue, S. Mannion","doi":"10.22038/PSJ.2020.48968.1275","DOIUrl":"https://doi.org/10.22038/PSJ.2020.48968.1275","url":null,"abstract":"Introduction: While anesthesia is regarded as one of the safest clinical specialties, continuing to ensure patient safety requires vigilance. The growing complexity of modern medicine makes it extremely dangerous to rely on the absence of human error. There is evidence to suggest that anesthesiologists are less inclined to use checklists than surgeons and nurses. Seniority has also been shown to dictate the acceptance of checklists. Materials and Methods: We assessed compliance with, and attitudes to an anesthesia checklist, comparing by seniority. 1. Analysed a representative sample (n=247, 95% CI, 5% ME) of general anesthesia cases performed in one year (n=747), calculating percentage compliance in each case. We compared groups by seniority with Mann-Whitney U testing using SPSS. 2. We assessed attitudes using a 20-item questionnaire, consisting of five themed sub-scales. Descriptive statistics were generated. Results: Mean total compliance with the checklist was 91.6% (95% CI: 90.6-92.6%). Non-Consultant compliance was estimated at 94.4% (95% CI: 93.0-95.8%), compared to 91.6% (95% CI: 89.5-93.7%) in the Consultant group. Higher Non-Consultant compliance was significant, compared to the Consultant group (P=0.045). Conclusion: The Non-Consultant group demonstrated greater compliance. Attitudes to the checklist were similar amongst the two groups with lack of time and lack of training cited as two major barriers to use. Both senior and junior anesthesiologists felt it had a positive impact on patient safety.","PeriodicalId":16681,"journal":{"name":"Journal of patient safety and quality improvement","volume":"35 1","pages":"69-76"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89707875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemoptysis and Upper Gastrointestinal Bleeding In Two Patients Presenting With Aluminum Phosphate Intoxication (Oral and Inhaled): A Case Study 两例磷酸铝中毒(口服和吸入)患者的咯血和上消化道出血:一个病例研究

Journal of patient safety and quality improvement Pub Date : 2020-01-01 DOI: 10.22038/PSJ.2020.46055.1261

E. Moradi, H. Mokhtari, S. Sadrzadeh, B. Kakhki

{"title":"Hemoptysis and Upper Gastrointestinal Bleeding In Two Patients Presenting With Aluminum Phosphate Intoxication (Oral and Inhaled): A Case Study","authors":"E. Moradi, H. Mokhtari, S. Sadrzadeh, B. Kakhki","doi":"10.22038/PSJ.2020.46055.1261","DOIUrl":"https://doi.org/10.22038/PSJ.2020.46055.1261","url":null,"abstract":"Introduction: The inhalation of aluminum phosphate and ingestion of aluminum phosphate tablets lead to clinical toxicity with different and nonspecific clinical symptoms. Two patients referred to Imam Reza Hospital Poisoning Emergency Center of Mashhad, Iran, one of whom was a 28-year-old male with oral consumption of four aluminum phosphide tablets, and the second case was a 29-year-old woman who was poisoned by inhalation. Both cases had symptoms of pulmonary and upper gastrointestinal bleeding during the brief hospitalization that resulted in their mortalities. Case Report: The first case is a 29-year-old man who consumed four oral tablets about 1.5 h before referral. He was intubated with the evidence of hemoptysis and upper gastrointestinal bleeding after about 4 h. The second patient is a young woman who had abdominal pain, nausea, and vomiting since the day before referral, and she told that she did not have any underlying diseases. During stabilization and patient evaluation, she suddenly became unresponsive with asystole. The CPR started with the evidence of hemorrhage within the intubation tube. Conclusion: There are currently no studies or reports of hemorrhagic complications in patients. In these two cases, there was no evidence of pulmonary hemorrhage and upper gastrointestinal bleeding which warrants further investigation and evaluation considering that these patients were young and with no underlying disease.","PeriodicalId":16681,"journal":{"name":"Journal of patient safety and quality improvement","volume":"1 1","pages":"65-67"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83057517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Tranexamic Acid Effect on Consequences of Upper Gastrointestinal Bleeding in Patients Referring to the Emergency Department; a Randomized Clinical Trial 氨甲环酸对急诊患者上消化道出血后果的影响随机临床试验

Journal of patient safety and quality improvement Pub Date : 2020-01-01 DOI: 10.22038/PSJ.2020.43904.1246

Morteza Talebi Doluee, S. Sadrzadeh, Elnaz Vafadar-Moradi, Hamid Zamani Moghadam, Sanaz Javdani

{"title":"Evaluation of Tranexamic Acid Effect on Consequences of Upper Gastrointestinal Bleeding in Patients Referring to the Emergency Department; a Randomized Clinical Trial","authors":"Morteza Talebi Doluee, S. Sadrzadeh, Elnaz Vafadar-Moradi, Hamid Zamani Moghadam, Sanaz Javdani","doi":"10.22038/PSJ.2020.43904.1246","DOIUrl":"https://doi.org/10.22038/PSJ.2020.43904.1246","url":null,"abstract":"Introduction: Upper gastrointestinal bleeding is one of the major and emergent causes of mortality and morbidity around the world. The tranexamic acid has been raised since years ago as a therapeutic intervention. Therefore, prize of exact and timely treatment of upper gastrointestinal bleeding, the present study aimed to evaluate the effects of systemic tranexamic acid on the possible consequences of upper gastrointestinal bleeding such as need for blood transfusion, admission in intensive care unit (ICU), surgery to control bleeding or eventually short-term mortality. Materials and Methods: This double-blind randomized clinical trial included 88 patients with upper gastrointestinal bleeding in a referral academic gastrointestinal center. Patients with symptoms of upper gastrointestinal bleeding referred to the emergency department were randomly divided into two groups: intervention group (n=45) who treated with tranexamic acid in addition to receive standard therapy for upper gastrointestinal bleeding, and control group (n=43) treated with standard therapy for upper gastrointestinal bleeding and placebo (distilled water). Results: Administration of tranexamic acid along with the standard therapy for upper gastrointestinal bleeding in the intervention group caused reduction in mortality and recurrent bleeding compared to the control group. There is no difference between two groups in need for surgery, hemotransfusion and ICU admission. Conclusion: Due to the beneficial effects of tranexamic acid administration on reducing mortality and bleeding recurrence in patients with upper gastrointestinal bleeding, added this drug to the standard therapy may have a favorable potential for upper gastrointestinal bleeding.","PeriodicalId":16681,"journal":{"name":"Journal of patient safety and quality improvement","volume":"6 1","pages":"31-36"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86922647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0