Medicinal Chemistry of Neglected and Tropical Diseases最新文献

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New Chemical Scaffolds to Selectively Target the Trypanothione Metabolism 选择性靶向锥虫硫酮代谢的新化学支架
Medicinal Chemistry of Neglected and Tropical Diseases Pub Date : 2019-08-15 DOI: 10.1201/9781351011655-11
A. Ilari, G. Colotti
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引用次数: 0
Recent Advances in Repositioning Non-Antibiotics against Tuberculosis and other Neglected Tropical Diseases 结核病和其他被忽视的热带病非抗生素重新定位的最新进展
Medicinal Chemistry of Neglected and Tropical Diseases Pub Date : 2019-08-15 DOI: 10.1201/9781351011655-7
M. Semenya
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引用次数: 0
The Renewal of Interest in Nitroaromatic Drugs 硝基芳香族药物研究的新进展
Medicinal Chemistry of Neglected and Tropical Diseases Pub Date : 2019-08-15 DOI: 10.1201/9781351011655-12
N. Primas, C. Ducros, P. Vanelle, P. Verhaeghe
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引用次数: 2
Curcumin and Neglected Infectious Diseases 姜黄素与被忽视的传染病
Medicinal Chemistry of Neglected and Tropical Diseases Pub Date : 2019-08-15 DOI: 10.1201/9781351011655-14
F. Mazzacuva, A. Cilibrizzi
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引用次数: 1
Hits and Lead Discovery in the Identification of New Drugs against the Trypanosomatidic Infections 抗锥虫病新药的研究进展及新发现
Medicinal Chemistry of Neglected and Tropical Diseases Pub Date : 1900-01-01 DOI: 10.1201/9781351011655-10
T. Calogeropoulou, George E. Magoulas, Ina Pöhner, R. Wade, Joanna Panecka-Hofman, Pasquale, Linciano, S. Ferrari, Maria Paola Costi, N. Santarém, Ma., Dolores M. Jiménez‐Antón, A. I. Olías-Molero, Anabela, C. Silva, J. M. Alunda
{"title":"Hits and Lead Discovery in the Identification of New Drugs against the Trypanosomatidic Infections","authors":"T. Calogeropoulou, George E. Magoulas, Ina Pöhner, R. Wade, Joanna Panecka-Hofman, Pasquale, Linciano, S. Ferrari, Maria Paola Costi, N. Santarém, Ma., Dolores M. Jiménez‐Antón, A. I. Olías-Molero, Anabela, C. Silva, J. M. Alunda","doi":"10.1201/9781351011655-10","DOIUrl":"https://doi.org/10.1201/9781351011655-10","url":null,"abstract":"The Neglected Tropical Diseases (NTDs) are a group of 17 pathologies, recognized by the World Health Organization (WHO), which are endemic in 149 countries of tropical and sub-tropical areas of the globe, and affect more than one billion people overall (Feasey et al. 2010). The pathologies are all caused by microparasites or macroparasites. Among the diseases provoked by microparasites, three are caused by kinetoplastidae, a group of flagellated protozoa transmitted by insect vectors: Chagas disease, Human African Trypanosomiasis and leishmaniasis. The focus of the present chapter is on the identification of new drugs for the treatment of trypanosomatidic infections such as Chagas disease, caused by Trypanosoma cruzi, and Human African Trypanosomiasis, caused by Trypanosoma brucei (Filardy et al. 2018).","PeriodicalId":166352,"journal":{"name":"Medicinal Chemistry of Neglected and Tropical Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128805463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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