Journal of orthopaedics最新文献

{"title":"Exploration of research hotspots and evolutionary trends in osteosarcoma pulmonary metastasis: A comprehensive bibliometric analysis spanning five decades","authors":"Chaojie Yu ,&nbsp;Xiaohua Jiang ,&nbsp;Shutian Wei ,&nbsp;Chengxing Zhou ,&nbsp;Chengyu Zhou ,&nbsp;Yanshan Wei ,&nbsp;Zhiping Su","doi":"10.1016/j.jor.2025.03.053","DOIUrl":"10.1016/j.jor.2025.03.053","url":null,"abstract":"<div><h3>Objective</h3><div>Pulmonary metastasis frequently complicates osteosarcoma, making the investigation of its mechanisms and therapeutic strategies a focal point in both clinical medicine and biosciences. The explosive growth of the relevant literature has still not been systematically sorted out and summarized.</div></div><div><h3>Methods</h3><div>Bibliometric methods were used in this study, Literature was retrieved from the Web of Science Core Collection, SCOPUS, and PubMed up until July 1, 2024. Bibliometric indicators were analyzed and research trends and hotspots in the field visualized using the Bibliometrix package, VOSviewer 1.6.19 and Citespace 6.3.R1 software.</div></div><div><h3>Results</h3><div>A total of 1148 publications were reviewed, revealing that over the past five decades, the cumulative number of publications on pulmonary metastasis of osteosarcoma has gradually increased. China leads in the number of published papers, while the United States exhibits the most collaborative relationships with other countries. Italy is noted for the highest quality of research. Sun Yat-sen University is the most prolific institution, and the most productive author is Eugenie S. Kleinerman from the University of Texas MD Anderson Cancer Center. “Cancer” is the journal with the most publications, and Zhou Yan's 2020 paper received the highest local citations. Keywords such as “angiogenesis,” “tumor microenvironment,” and “surgery” appeared frequently, suggesting these topics are current research hotspots.</div></div><div><h3>Conclusion</h3><div>“Immunotherapy”, “survival”, “chemotherapy”, “prognosis”, “biomarkers”, “metastasectomy”, “microRNA”, “angiogenesis”, “tumor microenvironment”, and “surgery” define key research areas. Current hot topics include tumor-associated macrophages and the tumor microenvironment, which may hold the key to future therapeutic breakthroughs.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"63 ","pages":"Pages 181-195"},"PeriodicalIF":1.5,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of various physical modalities on pain in patients with knee osteoarthritis: A network meta-analysis","authors":"Xin Zhou ,&nbsp;Yating Yu ,&nbsp;Jinwei Guo ,&nbsp;Liezhen Cao ,&nbsp;Xiaohua Zhang ,&nbsp;Zhongliang Deng","doi":"10.1016/j.jor.2025.03.045","DOIUrl":"10.1016/j.jor.2025.03.045","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to evaluate the effectiveness of various physical therapy methods in reducing pain for patients with knee osteoarthritis (KOA) through a network meta-analysis.</div></div><div><h3>Methods</h3><div>We conducted a comprehensive search across multiple databases, including PubMed, Embase, Cochrane Library, VIP, WanFang Data, and CNKI, to identify randomized controlled trials (RCTs) on physical therapies for KOA. The search spanned from the inception of each database to October 2024. The methodological quality of the studies was assessed using the Cochrane Handbook. Pain was measured using tools such as the visual analog scale, numeric pain rating scale, and the Western Ontario and McMaster University Osteoarthritis Index. All pain scores were standardized to a 10-point scale. Data collection and analysis were performed independently by two researchers using Stata 15.0 software.</div></div><div><h3>Results</h3><div>The analysis included 64 studies with 3855 patients and 12 physical therapy modalities. Based on the surface under the cumulative ranking curve (SUCRA), the most effective treatments were HILT, ESWT, Hydrotherapy, Land-EX, LLLT, Braces, tDCS, US, IFCs, SWD, Insoles, and TENS.</div></div><div><h3>Conclusion</h3><div>HILT appears to be the most effective treatment for pain relief in KOA patients. Further large-scale RCTs are needed to confirm these findings.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"63 ","pages":"Pages 171-180"},"PeriodicalIF":1.5,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143800584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of soft tissue balancing and component alignment in computer-navigated TKA for valgus knee","authors":"Takuya Naraoka ,&nbsp;Hikaru Soneda ,&nbsp;Runa Hori ,&nbsp;So Morioka ,&nbsp;Yukihiro Matsuyama","doi":"10.1016/j.jor.2025.03.054","DOIUrl":"10.1016/j.jor.2025.03.054","url":null,"abstract":"<div><h3>Purpose</h3><div>Computer-navigated total knee arthroplasty (CN-TKA) is useful for improving the accuracy of osseous cuts, soft tissue balance, and component placement. However, the usefulness of CN-TKA for valgus deformity remains unclear. This study aimed to assess the availability of CN-TKA for valgus deformities and compare it with CN-TKA for varus knees.</div></div><div><h3>Methods</h3><div>A total of 74 cruciate-retaining CN-TKAs (20 valgus, 54 varus) were included in this study. After implantation, the intraoperative hip-knee-ankle (HKA) angle was recorded during full extension and at 30° and 90° of flexion under three conditions (no stress, valgus stress, and varus stress), and the medial and lateral laxities were calculated. The femorotibial angle (FTA), HKA angle, patellar tilt, mechanical lateral distal femoral angle (mLDFA), and mechanical medial proximal tibial angle (mMPTA) were measured on postoperative radiographs. The Knee Injury and Osteoarthritis Outcome Score (KOOS) and Lysholm score were determined at 1 year postoperatively.</div></div><div><h3>Results</h3><div>The lateral laxity of varus knee in full extension was significantly larger than that of valgus knee (valgus: 0.5 ± 0.7°, varus: 1.2 ± 1.0°, <em>p</em> = 0.011). The medial laxity of valgus knee at 90° of flexion was significantly larger than that of varus knee (valgus: 0.4 ± 0.6°, varus: 0.1 ± 0.3°, <em>p</em> = 0.004). There were no significant differences in the FTA, HKA angle, patellar tilt, mLDFA, mMPTA, KOOS scores, or Lysholme score between the two groups postoperatively.</div></div><div><h3>Conclusion</h3><div>CN-TKA for valgus knee demonstrated acceptable soft tissue balancing and component alignment and good early clinical results comparable to those of CN-TKA for varus knees.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"62 ","pages":"Pages 160-164"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal and regional trends of fractures in the United States: A review of the global burden of disease database","authors":"Nithin Gupta ,&nbsp;Hursch Patel ,&nbsp;Maxwell Kasmenn ,&nbsp;Rileigh T. Ricken ,&nbsp;Michael Anderson ,&nbsp;Morgan Turnow ,&nbsp;Taylor Manes ,&nbsp;Elizaveta Reznichenko ,&nbsp;Tyler K. Williamson ,&nbsp;Ravi Karia","doi":"10.1016/j.jor.2025.03.031","DOIUrl":"10.1016/j.jor.2025.03.031","url":null,"abstract":"<div><h3>Background</h3><div>Musculoskeletal diseases, including bone fractures, are a significant contributor to global disability. Understanding temporal and regional trends in bone fractures is crucial for effective healthcare planning and resource allocation. We sought to analyze recent epidemiological trends of different types of fractures in the United States and determine correlations and associations between fracture trends and potential influencing demographic factors (i.e. age, sex, regional-specific).</div></div><div><h3>Methods</h3><div>Data from the Global Burden of Disease Database were analyzed to examine fracture incidence, prevalence, and years lived with disability (YLDs). Statistical analyses were conducted to determine temporal trends and sex-based differences.</div></div><div><h3>Results</h3><div>The analysis revealed significant increases in hip fractures and decreases in pelvic fractures over time. Fractures of the patella, tibia, fibula, and ankle remain prevalent across all regions and sexes, with notable variations.</div></div><div><h3>Conclusions</h3><div>These findings underscore the importance of targeted interventions and resource allocation to address the burden of fractures on public health. Despite limitations, this study provides critical insights into fracture epidemiology, guiding future prevention and management strategies.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"62 ","pages":"Pages 207-215"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total hip arthroplasty with subtrochanteric osteotomy for severe developmental dysplasia of the hip: A systematic review and meta-analysis","authors":"Tomonori Shigemura,&nbsp;Yohei Yamamoto,&nbsp;Yasuaki Murata","doi":"10.1016/j.jor.2025.03.027","DOIUrl":"10.1016/j.jor.2025.03.027","url":null,"abstract":"<div><h3>Background</h3><div>Total hip arthroplasty (THA) for severe developmental dysplasia of the hip (DDH) is technically difficult because of the anatomical features of dysplasia, such as a hypoplastic and shallow acetabulum, narrow femoral canal, and soft tissue contractures. Subtrochanteric osteotomy (STO) is effective technique to reduce the risk of sciatic nerve palsy while placing the acetabular cup in an anatomical position during THA for severe DDH. Few studies have compared THA performed without STO to THA performed with STO. We performed a systematic literature review and single-arm meta-analysis to integrate the results of studies regarding THA with STO for severe DDH.</div></div><div><h3>Patients and methods</h3><div>A systematic literature review was conducted using relevant original studies from various databases. Pooling of data was performed using RevMan software. A <em>p</em>-value of &lt;0.05 was considered significant. The results are expressed as incidences with 95 % confidence intervals (CIs) for dichotomous data and means with 95 % CI for continuous data. Statistical heterogeneity was assessed based on <em>I</em>² using the standard χ² test. When <em>I</em>² &gt; 50 %, significant heterogeneity was assumed, and a random-effects model was applied for the meta-analysis. A fixed-effects model was applied in the absence of significant heterogeneity.</div></div><div><h3>Results</h3><div>Twelve studies were included in this meta-analysis. The pooled incidence of sciatic nerve palsy, delayed union or nonunion, dislocation, intraoperative femoral fracture, and infection were 2.44 % (95 % CI: 0.86–4.01), 2.74 % (95 % CI: 1.11–4.37), 2.92 % (95 % CI: 1.63–4.20), 2.19 % (95 % CI: 0.95–3.42), and 3.11 % (95 % CI: 0.10–6.12), respectively. Pooling of the data also showed a mean Harris Hip Score (HHS) of 88.33 (95 % CI: 84.95–91.70).</div></div><div><h3>Discussion</h3><div>Although THA with STO for severe DDH is a challenging surgical procedure, this meta-analysis showed that the results of THA with STO for severe DDH are favourable.</div><div><strong><em>Level of evidence:</em></strong> Ⅳ (systematic review and meta-analysis).</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"62 ","pages":"Pages 197-206"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Return to recreational activity after hip abductor repair: A systematic review","authors":"Aadi Sharma ,&nbsp;Suhas R. Velichala ,&nbsp;Phillip B. Wyatt ,&nbsp;Andrew S. Cuthbert ,&nbsp;Omar A. Protzuk ,&nbsp;John W. Cyrus ,&nbsp;Jonathan B. Goodloe","doi":"10.1016/j.jor.2025.03.058","DOIUrl":"10.1016/j.jor.2025.03.058","url":null,"abstract":"<div><h3>Background</h3><div>Hip abductor tears are a relatively common pathology that can impede activity and quality of life. Surgical repair may confer a greater ability to return to recreational activities; however, to our knowledge no systematic reviews have been conducted exploring this. The purpose of this study is to describe the ability to return to recreation following hip abductor repair, and identify any patient factors affecting post-surgical prognosis.</div></div><div><h3>Methods</h3><div>A systematic search of peer-reviewed studies published on and prior to February 15th, 2024 was conducted using Medline (Ovid), Embase, Cochrane, and CINAHL (EBSCO) in adherence with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards. The search included a combination of keywords and controlled vocabulary for the following concepts: <em>return to recreation</em> and <em>hip abductor repair</em>. Outcomes of interest included return to recreation beyond patient reported outcome measures, imaging, surgical indications, surgical methods/techniques, concomitant procedures, complications, reoperations, postoperative management, and sports related outcome scores if applicable.</div></div><div><h3>Results</h3><div>Across 5 studies, a total of 474 patients (41 males, 433 females) with a history of recreational activity and mean age of 69.92 years underwent repair. Two studies reported the number of patients returning to recreation, yielding a return rate of 76 %, with walking having the highest return (N = 26), and skiing, soccer, and horse-riding seeing no return. There was no difference in return based on procedural technique or concomitant procedures (<em>P</em> &gt; 0.05). The most common postsurgical complication was re-tear (N = 25) for which 20 patients underwent secondary repair. Across 4 studies, there was a weighted satisfaction rate of 91.47 % with return to recreation. The fifth study reported a satisfaction score of 8 out of 10.</div></div><div><h3>Conclusion</h3><div>With an aging population and a growing desire to maintain elevated levels of physical activity, the importance of assessing return to recreation following hip abductor repair is increasingly crucial. This study demonstrates a relatively high satisfaction rate while also underscoring a greater need to report specific activities when discussing postsurgical return to recreation.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"62 ","pages":"Pages 216-223"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143783086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of standing hyperextension lateral radiograph and full-length spine computed tomography scout view in the prone position in spinal flexibility assessment for patients with symptomatic old osteoporotic thoracolumbar fracture with kyphotic deformity: A comparative analysis","authors":"Xiubo Ge ,&nbsp;Yifei Li ,&nbsp;Wei Zhang ,&nbsp;Kangkang Wang ,&nbsp;Xilong Cui ,&nbsp;Haitao Lu ,&nbsp;Haiyang Yu","doi":"10.1016/j.jor.2025.03.043","DOIUrl":"10.1016/j.jor.2025.03.043","url":null,"abstract":"<div><h3>Background</h3><div>Accurate assessment of thoracolumbar kyphosis (TLK) flexibility is paramount in preoperative planning for patients with symptomatic old osteoporotic thoracolumbar fractures (so-OTLF) exhibiting kyphotic deformity. While conventional standing hyperextension lateral radiographs (SHLR) are utilized, comparative analyses with prone computed tomography (CT) scout views in the sagittal plane remain limited. This study aims to evaluate and compare the efficacy of SHLR and full-length spine CT (FLS-CT) scout views in the prone position for assessing TLK flexibility in so-OTLF patients.</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted on patients with so-OTLF and kyphotic deformity who underwent posterior corrective fusion surgery. Sagittal parameters were measured independently by two spine surgeons using standing radiographs, SHLR, and prone FLS-CT scout views. TLK flexibility was quantified as the difference between standing and either SHLR or FLS-CT measurements. Paired t-tests were employed to compare sagittal Cobb angles and TLK flexibility between hyperextension and prone positions. Intra- and interobserver reliability were assessed using the intraclass correlation coefficient (ICC).</div></div><div><h3>Results</h3><div>Thirty-four patients (mean age 66.1 ± 7.2 years, 30 females) were included. The mean TLK on standing radiographs was 50.9° ± 13.8°. SHLR demonstrated a mean TLK reduction of 7.8° (95 % CI: 6.6°–9.1°) to 43.1° ± 12.6° (P &lt; 0.05). FLS-CT revealed a mean TLK of 31.8° ± 12.4°, a reduction of 19.1° (95 % CI: 17.4°–20.9°) compared to standing radiographs (P &lt; 0.05). TLK flexibility in the prone position was significantly higher than in the hyperextension position (mean difference: 11.3°, P &lt; 0.001). Both SHLR and FLS-CT demonstrated high intra- and interobserver reliability (ICC &gt;0.82), with FLS-CT exhibiting superior reliability (intraobserver ICC: 0.97, interobserver ICC: 0.94) compared to SHLR (intraobserver ICC: 0.90, interobserver ICC: 0.82).</div></div><div><h3>Conclusions</h3><div>Prone FLS-CT scout views provide a more accurate assessment of TLK flexibility in patients with so-OTLF and kyphotic deformity compared to conventional SHLR. This enhanced accuracy may facilitate improved preoperative evaluation and surgical planning.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"62 ","pages":"Pages 191-196"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of risk factors for anterior knee pain following unicompartmental knee arthroplasty: A case-control study","authors":"Ziyou Yan ,&nbsp;Meiyi Chen ,&nbsp;Deng Li ,&nbsp;Zhiqing Cai ,&nbsp;Hao Sun ,&nbsp;Shuqiang Ma ,&nbsp;Ruofan Ma ,&nbsp;Jie Xu","doi":"10.1016/j.jor.2025.03.057","DOIUrl":"10.1016/j.jor.2025.03.057","url":null,"abstract":"<div><h3>Objective</h3><div>The objective of this study is to identify and analyze the risk factors associated with anterior knee pain (AKP) following unicompartmental knee arthroplasty (UKA) and to investigate the underlying mechanisms that contribute to this postoperative complication.</div></div><div><h3>Methods</h3><div>This case-control study encompassed 30 knees from 24 patients who underwent medial fixed-platform UKA for knee osteoarthritis between 2018 and 2022. Participants were categorized into two groups based on the presence or absence of postoperative AKP. Clinical and imaging data were collected. Logistic regression analysis was utilized to determine independent risk factors for AKP.</div></div><div><h3>Results</h3><div>Among the 30 knees assessed, 7 (23.3 %) exhibited AKP postoperatively, while 23 (76.7 %) did not report such pain. An analysis of imaging parameters revealed significant differences between the two groups regarding postoperative patellar tilt angle, trochlear groove angle, progression of medial patellofemoral arthritis, and postoperative medial tilt of the patella. Logistic regression analysis identified the progression of medial patellofemoral arthritis as an independent risk factor for the occurrence of AKP. Additionally, an increased patellar tilt angle was identified as a protective factor, whereas postoperative medial tilt of the patella was recognized as a risk factor.</div></div><div><h3>Conclusion</h3><div>The progression of medial patellofemoral arthritis is identified as an independent risk factor for AKP following fixed-platform UKA. The development of this condition may be influenced by postoperative patellar tilt and trochlear groove angle. These findings underscore the necessity for optimal implant positioning and effective soft tissue management during UKA to mitigate postoperative complications.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"62 ","pages":"Pages 175-181"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a personalized parametric finite element model of the knee: Evaluation of geometric variables affecting osteoarthritis progression","authors":"Fatemeh Abdollahpour ,&nbsp;Goldis Darbemamieh ,&nbsp;Mohammad Nikkhoo ,&nbsp;Kamran Hassani ,&nbsp;Sadegh Rahmati","doi":"10.1016/j.jor.2025.03.009","DOIUrl":"10.1016/j.jor.2025.03.009","url":null,"abstract":"<div><h3>Background</h3><div>Osteoarthritis is a degenerative condition that impacts synovial joints, particularly the knee joint. Researchers regard Finite Element Analysis as a promising technique for managing knee osteoarthritis. However, these models often depend on input geometry from one or more individuals, feature complex interfaces, and require a significant amount of time, which makes them unsuitable for clinical use and reduces their reliability.</div></div><div><h3>Purpose</h3><div>This study aims to assess the effectiveness of the personalized parametric model technique in predicting the knee joint's mechanical response, taking into account anatomical variables that influence osteoarthritis.</div></div><div><h3>Methods</h3><div>A 3D model of the knee was created from CT images of a patient with knee osteoarthritis. Lateral, anterior, and posterior knee radiographs were obtained from twenty-six subjects to customize the geometric parameters of the developed parametric model. The knee geometry was parameterized using Ansys software. The models used six parameters to represent the articular surface of the tibial plateau, its slope, and variables attached to the medial and lateral femoral condyles. Parametric FE models were created individually by applying the ground reaction force diagram to each model.</div></div><div><h3>Results</h3><div>Mean maximum von Mises stress was higher in the OA group than in the control group. Simulations of the patients in the OA group indicated that the mean von Mises stress at the articular surfaces diminished with an increase in tibial plateau tilt. Also, individual geometry-specific models exhibited varying responses, thereby confirming the significance of taking personalized geometry into account.</div></div><div><h3>Conclusion</h3><div>Personalized models can be used to simulate mechanical responses and specifically evaluate the effect of the tibial plateau tilt. This work presented an innovative method for creating individualized finite element models of osteoarthritic knees, which can be used as a practical and effective tool in clinical environments.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"62 ","pages":"Pages 165-174"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing and analyzing a Nanocomposites coated material for hammertoe implants","authors":"Gayathri Ramesh ,&nbsp;Vamsi Krishna Dommeti ,&nbsp;Hari Raj Kumar ,&nbsp;Gnanavel Sadasivam","doi":"10.1016/j.jor.2025.01.016","DOIUrl":"10.1016/j.jor.2025.01.016","url":null,"abstract":"<div><div>Hammertoe implants, frequently used for arthroplasty or proximal interphalangeal joint arthrodesis, have serious drawbacks because of bacterial colonization and material corrosion, which can result in infections and other problems. This study creates a new nanocomposite covering to improve the corrosion resistance, antibacterial qualities, and biocompatibility of 316L stainless steel (SS). 316L SS was treated with a nanocomposite made of graphene oxide (GO), zirconia (ZrO₂), and hydroxyapatite (HAp). The coating's structural and functional characteristics were examined using Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX). Standard assays were used to evaluate the coated material's antibacterial activity, and simulated bodily fluid (SBF) was used to assess corrosion resistance in vitro. Biocompatibility was verified using assays for cell survival. Apatite layer formation during SBF immersion indicated increased bioactivity and the results showed that the HAp-ZrO₂-GO nanocomposite coating greatly increased the corrosion resistance of 316L SS. The coating showed anti-inflammatory and potent antibacterial qualities, successfully preventing bacterial colonization. Additionally, cell survival tests verified the coated material's biocompatibility, indicating that it would be safe for use in biomedical applications. This work presents a scalable and reasonably priced process for creating bioactive nanocomposite coatings for medical implants. The HAp-ZrO₂-GO coating addresses important drawbacks of conventional implant materials by improving physico-chemical interactions and providing better performance. With significant ramifications for developing biomedical engineering and enhancing patient outcomes, these results demonstrate the potential of the HAp-ZrO₂-GO nanocomposite as a workable option for long-lasting, antimicrobial, and biocompatible bioimplant coatings.</div></div>","PeriodicalId":16633,"journal":{"name":"Journal of orthopaedics","volume":"62 ","pages":"Pages 182-190"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}