Oncology, Gastroenterology and Hepatology Reports最新文献

{"title":"To Assess the Efficacy and Safety of Various Anti-heliminthics against Ascariasis Lumbricoides among a Study Population in North India","authors":"Zaffar A. Kawoosa, G. Javid, G. Yattoo, G. M. Gulzar, J. Sodhi, Altaf Shah, M. Khan, S. Hamid","doi":"10.5530/OGH.2018.7.1.5","DOIUrl":"https://doi.org/10.5530/OGH.2018.7.1.5","url":null,"abstract":"Copyright © 2018 Phcog.Net. This is an openaccess article distributed under the terms of the Creative Commons Attribution 4.0 International license. Cite this article: Kawoosa Z, Javid G, Yattoo GN, Gulzar GM, Sodhi JS, Shah AH, Khan M, Hamid S. To Assess the Efficacy and Safety of Various Anti-heliminthics against Ascariasis Lumbricoides among a Study Population in North India. OGH Reports. 2018;7(1):25-34. ABSTRACT Introduction: More than 24% of the world’s population, are infected with soil-transmitted helminth infection. Aim: To assess the helminthic load & efficacy and safety of various antiheliminthics. Methods: A total of 400 patients who met the inclusion criteria were recruited after proper consent. Subjects were divided into Four groups (100 each) randomly & receive different antihelminthic drugs. Cure rate and egg reduction rate was used as a primary outcome measure. Three weeks later two more stool samples were analyzed by two methods 1) Direct Smear method & 2) Concentration method. On follow-up, each group were randomly assigned a single dose of albendazole (single 400 mg dose), mebendazole (100 mg, BD×3 days), pyrantel pamoate (11 mg/kg orally once) and ivermectin (0.2 mg/kg orally once) using a randomization procedure.The data was statistically analysed. Observations: Among 400 patients, 63% were 5-19 years of age, 68% were male, 73.5% were from rural areas, 71% were literate, 62% were in the low income group, 58% reported closed sanitation, 6.75% were having low BMI, 26.25% were having High Absolute Eosinophilic Count before treatment, 77.5% were non-anaemic. 92.5% did not have icterus. In the present study it was seen that the difference among the four drugs was statistically significant as per demographic variables. Significant decrease of worm load after treatment were comparable with each other. However, Presence of Worm across papillae seen after upper GI endoscopy and persistent biliary ascariasis was comparable in all the four drug groups. Overall, the efficacy of anthelmintic drugs was excellent and statistically significant (p<0.001). Conclusion: Albendazole and mebendazole having cure rates of 90% and also reducing the mean egg count by 90%. Also treatment of school children every 4 monthly may be necessary in high endemic areas, like ours. All these drugs which we used in our study are safe and no significant side effects were observed.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124972924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two and Half Years Later: Cytomegalovirus and Ebstein Barr Virus Infection Leading to Sinusoidal Obstruction Syndrome in Liver Transplant Recipient","authors":"C. Philips, P. Augustine, P. Mahadevan","doi":"10.5530/ogh.2018.7.1.6","DOIUrl":"https://doi.org/10.5530/ogh.2018.7.1.6","url":null,"abstract":"","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"94 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125982468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avascular Osteonecrosis of the Knee in a Post Liver Transplant Patient with Recurrent Cholangitis and Early Chronic Rejection","authors":"M. Premkumar, A. Choudhury, Senthil Kumar, V. Pamecha","doi":"10.5530/ogh.2018.7.1.15","DOIUrl":"https://doi.org/10.5530/ogh.2018.7.1.15","url":null,"abstract":"","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121705816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Scientometric Assessment of Obesity Research Publications from India during 2007-16","authors":"B. Gupta, K. Ahmed, Ritu Gupta","doi":"10.5530/OGH.2018.7.1.4","DOIUrl":"https://doi.org/10.5530/OGH.2018.7.1.4","url":null,"abstract":"","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129486996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FNAC of the Thyroid Following Carbimazole Therapy in Hyperthyroidism: A Diagnostic Dilemma","authors":"T. Santosh, Hemlata Panwar, B. Kumari, Vandita Singh, R. Arora, Nighat Hussain","doi":"10.5530/ogh.2018.7.1.7","DOIUrl":"https://doi.org/10.5530/ogh.2018.7.1.7","url":null,"abstract":"Copyright © 2018 Phcog.Net. This is an openaccess article distributed under the terms of the Creative Commons Attribution 4.0 International license. Cite this article: Santosh T, Panwar H, Kumari B, Singh VY, Arora RD, Hussain N. FNAC of the Thyroid Following Carbimazole Therapy in Hyperthyroidism: A Diagnostic Dilemma. OGH Reports. 2018;7(1):38-40. ABSTRACT Antithyroid drug therapy is routinely used for treatment of hyperthyroid patients. Therapy induced changes in hyperthyroidism can cause serious diagnostic dilemma on FNAC and have been rarely documented. We present a case of 45-year-old female patient who clinically presented with diffuse thyroid swelling and features of hyperthyroidism. FNAC from thyroid swelling showed features of Hashimoto’s thyroiditis / Grave’s disease / Colloid goiter with follicular hyperplasia and at places raising the suspicion of malignant transformation. Further clinical evaluation of patient, it was found that she had carbimazole therapy. Correlating the clinical and cytomorphologic features, a diagnosis of “therapy induced (carbimazole) changes in hyperthyroidism was given.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131725599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polycystic Ovary Syndrome Research: A Scientometric Assessment of Global Publications Output During 2007-16","authors":"Ritu Gupta, B. Gupta, K. Ahmed","doi":"10.5530/OGH.2018.7.1.3","DOIUrl":"https://doi.org/10.5530/OGH.2018.7.1.3","url":null,"abstract":"","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132199582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Levofloxacin Associated Fatal Oro-Facio-Brachial Dystonia in Cirrhosis","authors":"C. Philips, P. Augustine","doi":"10.5530/OGH.2018.7.1.8","DOIUrl":"https://doi.org/10.5530/OGH.2018.7.1.8","url":null,"abstract":"Copyright © 2018 Phcog.Net. This is an openaccess article distributed under the terms of the Creative Commons Attribution 4.0 International license. Cite this article: Philips CA, Augustine P. Levofloxacin associated fatal oro-facio-brachial dystonia in cirrhosis. OGH Reports. 2018;7(1):41-2. ABSTRACT Fluroquinolones are rarely associated with severe dystonic syndromes. We present the case of a middle aged cirrhotic who presented with severe fatal oro-facio-brachial dystonia secondary to intravenous levofloxacin use. Levofloxacin has been very rarely shown to be associated with such severe involuntary movement disorders. A commonly used antibiotic as part of anti-tubercular regimen, caution must be maintained for prevention of severe adverse reactions while using levofloxacin.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133245356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent Intussusception Secondary to Multiple Peutz-jegher polyps: An Unusual Case with Review of Literature","authors":"Chisel Bhatia, S. Dalal, Mahavir Singh, Jitendra Singh Malwal","doi":"10.5530/OGH.2018.7.1.9","DOIUrl":"https://doi.org/10.5530/OGH.2018.7.1.9","url":null,"abstract":"Copyright © 2018 Phcog.Net. This is an openaccess article distributed under the terms of the Creative Commons Attribution 4.0 International license. Cite this article: Bhatia C, Dalal S, Singh M, Malwal JS. Recurrent Intussusception Secondary to Multiple Peutz-jegher polyps: An Unusual Case with Review of Literature. OGH Reports. 2018;7(1):43-5. ABSTRACT Peutz-Jegher polyps are hamartomas of the small bowel which occur as part of the PeutzJegher syndrome, a rare autosomal dominant condition characterized by gastrointestinal polyps and mucocutaneous melanotic pigmentation. Here we report the case of a young male suffering from this syndrome who presented with acute intestinal obstruction due to intussception. Exploratory laparotomy was done which revealed jejuno-jejunal and jejunoileal intussusceptions for which resection and anastomosis was done. There were multiple intraluminal polyps in the jejunum which on histopathological examination, showed features of Peutz-Jegher Polyp. Patient behaved well in the post-operative period and is still on follow up with us.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123293808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Incidental Occurrence of Mantle Cell Lymphoma with Alcoholic Liver Disease and Pancreatitis","authors":"R. Sareen, Menka Kapil, G. Gupta, D. Agrawal","doi":"10.5530/ogh.2018.7.1.11","DOIUrl":"https://doi.org/10.5530/ogh.2018.7.1.11","url":null,"abstract":"Copyright © 2018 Phcog.Net. This is an openaccess article distributed under the terms of the Creative Commons Attribution 4.0 International license. Cite this article: Sareen R, Kapil M, Gupta GN, Agrawal D. Rare Incidental Occurrence of Mantle Cell Lymphoma with Alcoholic Liver Disease and Pancreatitis. OGH Reports. 2018;7(1):49-52. ABSTRACT We present an extremely rare case of Mantle cell Lymphoma with concomitant alcoholic liver disease and pancreatitis in a 48 year old male patient. There was absence of abdominal lymphadenopathy. The complete blood count showed absolute lymphocytosis which on subsequent peripheral blood examination showed small to medium sized atypical cells raising suspicion of prolymphocytic leukemia. The flow cytometry and Immunohistochemistry examination confirmed Mantle cell lymphoma. The morphology of cells in mantle cell lymphoma are known to mimic prolymphocytes on peripheral blood. However, the rare concomitant occurrence of both diseases makes the case an interesting one for readers and emphasizes on the usefulness of peripheral blood examination although not completely diagnostic but raising an alarm for the diagnosis of this rare lymphoma.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128998417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First Case Report of F-18 FDG PET/CT in a Rare Case of Bilateral Adrenal and Lung Metastasis from Primary Hepatic Angiosarcoma","authors":"K. Kamaleshwaran, E. K. Radhakrishnan, R. Jose, A. Shinto","doi":"10.5530/ogh.2018.7.1.16","DOIUrl":"https://doi.org/10.5530/ogh.2018.7.1.16","url":null,"abstract":"Copyright © 2018 Phcog.Net. This is an openaccess article distributed under the terms of the Creative Commons Attribution 4.0 International license. Cite this article: Kamaleshwaran KK, Radhakrishnan EK, Jose RP, Shinto AS. First case report of F-18 FDG PET/CT in a Rare case of Bilateral adrenal and lung metastasis from primary hepatic angiosarcoma. OGH Reports. 2018;7(1):75-6. ABSTRACT Hepatic angiosarcoma is a very rare disease, accounting for only 2% of primary liver malignancy. They are rare tumours with poor prognosis, with patients usually dying within 6 months. Metastases mainly occur in lymph nodes, spleen, lungs, bones and adrenals. There are some studies that reported the use of Fluroine -18 Fluorodeoxyglucose (FDG)-positron emission tomography (PET)/ computer tomography (CT)(F 18 FDG PET/CT) in angiosarcomas (hepatic, cardiac, venous and cutaneous angiosarcomas) in the literature. Bilateral adrenal metastasis from angiosarcoma of liver is a rare phenomenon. We report the first case of 36 year old patient, angiosarcoma of liver, post right lobe hepatectomy status, presented with bilateral adrenal and lung metastases imaged using F18 FDG PET/CT.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129331887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}