Journal of Otolaryngology - Head & Neck Surgery最新文献

筛选
英文 中文
Alternative Sources of Cautery in Thyroid Surgery and the Risk of Recurrent Laryngeal Nerve Injury: A Retrospective, Risk-Adjusted Analysis From the National Surgical Quality Improvement Program. 甲状腺手术中灼烧剂的替代来源与喉神经复发性损伤的风险:国家外科手术质量改进计划的回顾性风险调整分析》。
IF 2.6 3区 医学
Journal of Otolaryngology - Head & Neck Surgery Pub Date : 2024-01-01 DOI: 10.1177/19160216241265687
Corliss A E Best, Jumana Hussain, Stephanie Johnson-Obaseki
{"title":"Alternative Sources of Cautery in Thyroid Surgery and the Risk of Recurrent Laryngeal Nerve Injury: A Retrospective, Risk-Adjusted Analysis From the National Surgical Quality Improvement Program.","authors":"Corliss A E Best, Jumana Hussain, Stephanie Johnson-Obaseki","doi":"10.1177/19160216241265687","DOIUrl":"10.1177/19160216241265687","url":null,"abstract":"<p><strong>Objectives: </strong>A risk-adjusted analysis was completed using data from the National Surgical Quality Improvement Program (NSQIP) to compare the rates of recurrent laryngeal nerve injury in thyroid surgery using traditional versus alternative sources of cautery (defined as Harmonic Scalpel<sup>©</sup> and LigaSure<sup>©</sup>).</p><p><strong>Methods: </strong>A retrospective cohort study was completed using the NSQIP database on adult patients who underwent total thyroidectomy, subtotal thyroidectomy, or completion thyroidectomy between 2016 and 2018. The primary outcome measure was recurrent laryngeal nerve injury. The exposure variable was use of conventional or alternative sources of cautery. Multivariable linear and logistic regression analyses were performed to control for potentially confounding variables.</p><p><strong>Results: </strong>A total of 13,961 cases were analyzed; 9450 used alternative sources of cautery compared to 4511 where traditional cautery was used. There was no significant difference in rates of postoperative recurrent laryngeal nerve injury between the 2 sources of cautery compared.</p><p><strong>Conclusions: </strong>Risk of recurrent laryngeal nerve injury should not be a factor when choosing method of cautery for thyroid surgery. Therefore, other factors like cost-effectiveness can be considered.</p>","PeriodicalId":16615,"journal":{"name":"Journal of Otolaryngology - Head & Neck Surgery","volume":"53 ","pages":"19160216241265687"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11284774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141788372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Necessary Factors for Efficient Frontal Sinus Irrigation After Endoscopic Sinus Surgery: A Systematic Review. 内窥镜鼻窦手术后有效冲洗额窦的必要因素:系统回顾
IF 2.6 3区 医学
Journal of Otolaryngology - Head & Neck Surgery Pub Date : 2024-01-01 DOI: 10.1177/19160216241269375
Yingting Qi, Junsheng Hong, Dawei Wu
{"title":"Necessary Factors for Efficient Frontal Sinus Irrigation After Endoscopic Sinus Surgery: A Systematic Review.","authors":"Yingting Qi, Junsheng Hong, Dawei Wu","doi":"10.1177/19160216241269375","DOIUrl":"10.1177/19160216241269375","url":null,"abstract":"<p><strong>Objective: </strong>The frontal sinus remains a challenging site for irrigation due to its position relative to the nostril and ethmoid sinus. This study aims to summarize the necessary factors for efficient irrigation of the frontal sinus after endoscopic sinus surgery (ESS) among patients with chronic rhinosinusitis (CRS).</p><p><strong>Methods: </strong>Using Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, a systematic literature review was conducted on PubMed, Scopus, and Cochrane databases to identify studies assessing the effect of frontal sinus irrigation in patients with CRS, cadaver models, or 3D-printed models of the sinonasal cavity after ESS.</p><p><strong>Results: </strong>Of the initial 206 abstracts reviewed, 18 full-text articles were included. The degree of the frontal sinus ostium opening after ESS was found to be associated with the efficacy of frontal sinus irrigation. More extensive frontal sinus surgeries tended to increase frontal sinus penetration. A Draf IIA procedure was identified as the minimum standard to achieve sufficient irrigation in the frontal sinus. Due to decreased backpressure in the nasal passage, increasing septectomy in Draf III did not significantly improve irrigation delivery. Squeeze bottles achieved significantly higher irrigation flow in the frontal sinus than syringes and pulsating devices. Large-volume irrigation devices provided better irrigation for the frontal sinus by entering or flushing the entire frontal sinus. The head position influenced the frontal sinus irrigation by altering the ostia position relative to fluid flow and vertical height of the frontal sinus during irrigation. While the vertex down head position was likely to enhance frontal sinus irrigation, the comfort of the head position and patient compliance should be considered.</p><p><strong>Conclusion: </strong>Elements for optimization of frontal sinus irrigation are a minimum of a Draf IlA procedure for frontal sinus dissection, use of large-volume irrigation, and vertex down head positioning. Developing comfortable head positions with high frontal sinus irrigation efficiency would increase patient compliance and improve outcomes.</p><p><strong>Level of evidence: </strong>NA.</p>","PeriodicalId":16615,"journal":{"name":"Journal of Otolaryngology - Head & Neck Surgery","volume":"53 ","pages":"19160216241269375"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11304481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brazilian Version of the Vestibular Activities and Participation Measure: Cross-Cultural Adaptation, Validity, and Reliability. 巴西版前庭活动和参与度测量:跨文化适应性、有效性和可靠性。
IF 2.6 3区 医学
Journal of Otolaryngology - Head & Neck Surgery Pub Date : 2024-01-01 DOI: 10.1177/19160216241250353
Maria das Graças de Araújo Lira, Susan L Whitney, Thais Cristina Chaves, Karyna Myrelly Oliveira Bezerra de Figueiredo-Ribeiro
{"title":"Brazilian Version of the Vestibular Activities and Participation Measure: Cross-Cultural Adaptation, Validity, and Reliability.","authors":"Maria das Graças de Araújo Lira, Susan L Whitney, Thais Cristina Chaves, Karyna Myrelly Oliveira Bezerra de Figueiredo-Ribeiro","doi":"10.1177/19160216241250353","DOIUrl":"10.1177/19160216241250353","url":null,"abstract":"<p><strong>Background: </strong>Vestibular Activities and Participation Measure (VAP) subscales assess the effect of vestibular disorders on activity and participation. This study aimed to perform the cross-cultural adaptation and assess the validity, internal consistency, reliability, and measurement error of the Brazilian version of VAP subscales.</p><p><strong>Methods: </strong>The cross-cultural adaptation followed the translation, synthesis, back-translation, review by a committee of experts, and pretesting phases. Structural validity was assessed using exploratory factor analysis (EFA) and confirmatory factor analysis (CFA), while Spearman's correlation between VAP subscales and the Dizziness Handicap Inventory (DHI) was used to assess construct validity. Cronbach's alpha measured internal consistency. Intraclass correlation coefficient (ICC) assessed intra- and inter-rater reliability, and measurement error was calculated by using the standard error of measurement (SEM) and minimal detectable change (MDC).</p><p><strong>Results: </strong>Additional information was included in the Brazilian version of the Vestibular Activities and Participation measure (VAP-BR) after approval by one of the developers of the instrument to improve the understanding among individuals. One factor was found in the EFA for each subscale with 50% explained variance. Regarding CFA, the subscales 1 (S1) and 2 (S2) presented, respectively, adequate model fit indices (ie, comparative fit index of 0.99 and 0.97, and standardized root mean square residual of 0.04 for both subscales), but a very low factor load in item 6 of S1 (0.08). Chronbach's alpha was 0.80 (S1) and 0.82 (S2). For intra-rater assessment, the S1 and S2 presented an ICC of 0.87 and 0.90, SEM of 0.01 and 1.16, and MDC of 0.39 and 0.46, respectively. When assessed by 2 different raters, SEM values were 1.03 and 1.53, and MDC values were 2.85 and 4.23 for S1 and S2, respectively; both subscales showed an ICC of 0.92. Correlations between DHI and VAP subscales presented coefficients above 0.57.</p><p><strong>Conclusion: </strong>The Brazilian version of VAP subscales presents good measurement properties and may assist health professionals in identifying activity limitations and participation restrictions in individuals with vestibular disorders.</p>","PeriodicalId":16615,"journal":{"name":"Journal of Otolaryngology - Head & Neck Surgery","volume":"53 ","pages":"19160216241250353"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11307343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Canadian Real-World Study Long-Term Clinical Results Using Dupilumab for Chronic Rhinosinusitis With Polyps. 加拿大真实世界研究使用杜比鲁单抗治疗慢性鼻窦炎伴息肉的长期临床结果。
IF 2.6 3区 医学
Journal of Otolaryngology - Head & Neck Surgery Pub Date : 2024-01-01 DOI: 10.1177/19160216241278659
Shaun J Kilty, Andrea Lasso
{"title":"Canadian Real-World Study Long-Term Clinical Results Using Dupilumab for Chronic Rhinosinusitis With Polyps.","authors":"Shaun J Kilty, Andrea Lasso","doi":"10.1177/19160216241278659","DOIUrl":"10.1177/19160216241278659","url":null,"abstract":"<p><strong>Background: </strong>Dupilumab, an anti-IL4 receptor-α monoclonal antibody, was the first biologic to be approved in Canada for the treatment of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). In phase III clinical trials, it has demonstrated to be effective in reducing nasal polyp size and the severity of symptoms, improve disease-specific quality of life, and to have an acceptable safety profile. This study aims to present long-term follow-up data on disease-specific sinonasal outcomes of patients with CRSwNP who have been treated with dupilumab for up to 3 years in a real-world setting.</p><p><strong>Methods: </strong>Retrospective review of electronic medical records of a single Canadian rhinology center evaluating disease-specific sinonasal outcomes that are routinely collected for clinical care. This study included all patients who received dupilumab for the treatment of CRSwNP and who had completed at least one follow-up visit. The Sino-Nasal Outcome Test (SNOT)-22 was used to evaluate treatment symptom improvement.</p><p><strong>Results: </strong>Ninety-nine patients started dupilumab therapy during the study period. The mean SNOT-22 at the start of therapy was 61.1 (±22.91) At the time of the review, 65 patients had completed 1 year of therapy, 40 had completed 2 years of therapy, and 18 had completed 3 years of therapy. The mean SNOT-22 score at these timepoints was 16.75 (±13.86), 15.02 (±14.40), and 10.22 (±11.56), respectively.</p><p><strong>Conclusion: </strong>This real-world study shows that in patients with CRSwNP treated with dupilumab, improvement in disease-specific quality of life seen after 1 year continues and can be maintained at 3 years of treatment.</p>","PeriodicalId":16615,"journal":{"name":"Journal of Otolaryngology - Head & Neck Surgery","volume":"53 ","pages":"19160216241278659"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142348613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proposed Quality Indicators for Aspects of Pediatric Acute Otitis Media Management. 小儿急性中耳炎管理质量指标建议。
IF 3.4 3区 医学
Journal of Otolaryngology - Head & Neck Surgery Pub Date : 2024-01-01 DOI: 10.1177/19160216241248538
Justin Cottrell, Amirpouyan Namavarian, Jonathan Yip, Paolo Campisi, Neil K Chadha, Ali Damji, Paul Hong, Sophie Lachance, Darren Leitao, Lily H P Nguyen, Natasha Saunders, Julie Strychowsky, Warren Yunker, Jean-Philippe Vaccani, Yvonne Chan, John R de Almeida, Antoine Eskander, Ian J Witterick, Eric Monteiro
{"title":"Proposed Quality Indicators for Aspects of Pediatric Acute Otitis Media Management.","authors":"Justin Cottrell, Amirpouyan Namavarian, Jonathan Yip, Paolo Campisi, Neil K Chadha, Ali Damji, Paul Hong, Sophie Lachance, Darren Leitao, Lily H P Nguyen, Natasha Saunders, Julie Strychowsky, Warren Yunker, Jean-Philippe Vaccani, Yvonne Chan, John R de Almeida, Antoine Eskander, Ian J Witterick, Eric Monteiro","doi":"10.1177/19160216241248538","DOIUrl":"10.1177/19160216241248538","url":null,"abstract":"<p><strong>Background: </strong>The high incidence of pediatric acute otitis media (AOM) makes the implications of overdiagnosis and overtreatment far-reaching. Quality indicators (QIs) for AOM are limited, drawing from generalized upper respiratory infection QIs, or locally developed benchmarks. Recognizing this, we sought to develop pediatric AOM QIs to build a foundation for future quality improvement efforts.</p><p><strong>Methods: </strong>Candidate indicators (CIs) were extracted from existing guidelines and position statements. The modified RAND Corporation/University of California, Los Angeles (RAND/UCLA) appropriateness methodology was used to select the final QIs by an 11-member expert panel consisting of otolaryngology-head and neck surgeons, a pediatrician and family physician.</p><p><strong>Results: </strong>Twenty-seven CIs were identified after literature review, with an additional CI developed by the expert panel. After the first round of evaluations, the panel agreed on 4 CIs as appropriate QIs. After an expert panel meeting and subsequent second round of evaluations, the panel agreed on 8 final QIs as appropriate measures of high-quality care. The 8 final QIs focus on topics of antimicrobial management, specialty referral, and tympanostomy tube counseling.</p><p><strong>Conclusions: </strong>Evidence of variable and substandard care persists in the diagnosis and management of pediatric AOM despite the existence of high-quality guidelines. This study proposes 8 QIs which compliment guideline recommendations and are meant to facilitate future quality improvement initiatives that can improve patient outcomes.</p>","PeriodicalId":16615,"journal":{"name":"Journal of Otolaryngology - Head & Neck Surgery","volume":"53 ","pages":"19160216241248538"},"PeriodicalIF":3.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141419598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost-Effectiveness Analysis of Molecular Testing for Indeterminate Thyroid Nodules in Nova Scotia. 新斯科舍省甲状腺结节不确定分子检测的成本效益分析。
IF 2.6 3区 医学
Journal of Otolaryngology - Head & Neck Surgery Pub Date : 2024-01-01 DOI: 10.1177/19160216241291806
Colin MacKay, Brooke Turner, Scott Clarke, Timothy Wallace, Matthew H Rigby
{"title":"Cost-Effectiveness Analysis of Molecular Testing for Indeterminate Thyroid Nodules in Nova Scotia.","authors":"Colin MacKay, Brooke Turner, Scott Clarke, Timothy Wallace, Matthew H Rigby","doi":"10.1177/19160216241291806","DOIUrl":"10.1177/19160216241291806","url":null,"abstract":"<p><strong>Background: </strong>The objective of the following retrospective review was to perform a cost-effectiveness analysis of the use of molecular testing of indeterminate thyroid nodules compared to current management practices in Nova Scotia, Canada.</p><p><strong>Methods: </strong>All cases of cytologically indeterminate thyroid nodules from January 1st, 2014 to December 31st, 2018 were reviewed. All interventions related to an indeterminate thyroid nodule were recorded. Patients were excluded if less than 18 years old if no further information regarding medical management was electronically available beyond the diagnosis of an indeterminate thyroid nodule, history of radiation, or previous thyroid surgery prior to diagnosis of an indeterminate thyroid nodule in the remaining lobe. Microcosting was performed to determine the cost of all relevant interventions including repeat fine needle aspiration biopsy, ultrasound, thyroid surgery(s), and molecular testing. Institution-specific transition state probabilities were calculated and used to build a cost-effectiveness analysis model. Model output was an incremental cost-effectiveness ratio, defined as the ratio of cost difference to effectiveness difference between routine molecular testing and the current management strategy, yielding cost per surgery avoided.</p><p><strong>Results: </strong>The mean effectiveness of the current management of indeterminate thyroid nodules in Nova Scotia based on the American Thyroid Association guidelines is 64% at a mean cost of $6431, while the simulated mean effectiveness of routine molecular testing is 89% at a mean cost of $8414. Differences in management strategies generated an incremental cost-effectiveness ratio of $7876 per surgery avoided.</p><p><strong>Conclusion: </strong>Routine molecular testing is the more effective strategy for the appropriate management of indeterminate thyroid nodules; however, it comes at a higher mean cost compared to the current management strategy. As the cost of molecular testing continues to decrease, and the cost of OR resources continues to rise, molecular testing is likely to become the optimal strategy in Nova Scotia.</p>","PeriodicalId":16615,"journal":{"name":"Journal of Otolaryngology - Head & Neck Surgery","volume":"53 ","pages":"19160216241291806"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11494664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of the "LAser Surgical skills Evaluation for Residents" (LASER) Scale Through a Modified Delphi Method. 通过改良德尔菲法开发 "住院医师手术技能评估"(LASER)量表。
IF 2.6 3区 医学
Journal of Otolaryngology - Head & Neck Surgery Pub Date : 2024-01-01 DOI: 10.1177/19160216241278654
E Sédillot-Daniel, A Melkane, C Chiesa, N Fakhry, V N Young, L J Smith, J R Lechien, L Guertin, M J Olivier, A Maniakas, R Jun Lin, E Bissada, A Christopoulos, T Ayad, Andrée-Anne Leclerc
{"title":"Development of the \"LAser Surgical skills Evaluation for Residents\" (LASER) Scale Through a Modified Delphi Method.","authors":"E Sédillot-Daniel, A Melkane, C Chiesa, N Fakhry, V N Young, L J Smith, J R Lechien, L Guertin, M J Olivier, A Maniakas, R Jun Lin, E Bissada, A Christopoulos, T Ayad, Andrée-Anne Leclerc","doi":"10.1177/19160216241278654","DOIUrl":"10.1177/19160216241278654","url":null,"abstract":"<p><strong>Background: </strong>The CO<sub>2</sub> laser is frequently used during microlaryngeal surgery (MLS) for a variety of pathology including laryngeal malignancy and stenosis. Learning how to use the laser safely is part of the curriculum for every otolaryngology resident. However, assessment of laryngoscopy technical skills can be challenging for supervisors, making it difficult to adequately provide feedback to trainees.</p><p><strong>Objectives: </strong>\"LAser Surgical skills Evaluation for Residents\" (LASER) Scale aims to facilitate the evaluation of residents' performance and promote constructive feedback.</p><p><strong>Methods: </strong>The initial evaluation grid was based on a literature review of CO<sub>2</sub> laser laryngoscopy (with an emphasis on indications, technique, safety, and efficacy) using Covidence systematic review software (Veritas Health Innovation). The final version was produced after 4 rounds of Delphi surveys.</p><p><strong>Results: </strong>This study was an international collaboration including 15 otolaryngologists with either laryngology or head and neck surgery subspecialties. Panelists were based in Canada (8), the United States (3), France (1), Spain (1), Belgium (1), and Lebanon (1). The process involved 4 rounds of Delphi surveys. Assessment categories included: anesthesia considerations, pre- and perioperative laser safety measures, and surgical technique. Consensus was reached on final survey completion.</p><p><strong>Conclusions: </strong>Through a modified Delphi method, a novel scale was developed through an international collaborative effort that evaluates resident skillset in CO<sub>2</sub> laser MLS. Future studies are warranted to validate this assessment tool.</p>","PeriodicalId":16615,"journal":{"name":"Journal of Otolaryngology - Head & Neck Surgery","volume":"53 ","pages":"19160216241278654"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Upfront Surgery Versus Upfront Concurrent Chemoradiotherapy as Primary Modality in Hypopharyngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. 下咽鳞状细胞癌前期手术与同期化放疗作为主要治疗方式的比较:系统回顾与 Meta 分析。
IF 2.6 3区 医学
Journal of Otolaryngology - Head & Neck Surgery Pub Date : 2024-01-01 DOI: 10.1177/19160216241293633
Tsung-You Tsai, Wing-Keen Yap, Ting-Hao Wang, Yi-An Lu, Anna See, Yu-Feng Hu, Yenlin Huang, Huang-Kai Kao, Kai-Ping Chang
{"title":"Upfront Surgery Versus Upfront Concurrent Chemoradiotherapy as Primary Modality in Hypopharyngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.","authors":"Tsung-You Tsai, Wing-Keen Yap, Ting-Hao Wang, Yi-An Lu, Anna See, Yu-Feng Hu, Yenlin Huang, Huang-Kai Kao, Kai-Ping Chang","doi":"10.1177/19160216241293633","DOIUrl":"10.1177/19160216241293633","url":null,"abstract":"<p><strong>Importance: </strong>The management of hypopharyngeal squamous cell carcinoma (HPSCC) continues to be one of the most formidable challenges in the realm of head and neck oncology.</p><p><strong>Objectives: </strong>The aim of this meta-analysis was to evaluate the disparity in survival outcomes between upfront surgery and upfront concurrent chemoradiotherapy as the primary treatment modality in patients with HPSCC.</p><p><strong>Design: </strong>Systemic review with meta-analysis.</p><p><strong>Setting: </strong>The meta-analysis was conducted in strict accordance with the PRISMA guideline. A literature search through PubMed, EMBASE, and the Cochrane Library were conducted until January 2023. The adjusted hazard ratio (aHR) with 95% confidence intervals (CIs) of different survival outcomes were extracted and pooled.</p><p><strong>Participants: </strong>Studies that incorporated HPSCC patients without receiving induction chemotherapy.</p><p><strong>Interventions: </strong>Upfront surgery versus upfront concurrent chemoradiotherapy.</p><p><strong>Main outcome measures: </strong>Overall survival (OS) and disease-free survival (DFS).</p><p><strong>Results: </strong>Eight studies published between 2015 and 2023, with a pooled patient population of 1619, were included in this meta-analysis. The outcomes reveal that upfront surgery was notably linked with improved OS (aHR 0.66, 95% CI 0.57-0.78) and DFS (aHR 0.75, 95% CI 0.63-0.90). Subgroup analyses were conducted to investigate the impact of the overall stage of the tumor and the extent of surgery on OS. In patients with advanced HPSCC (stages III and IV), upfront surgery remained associated with better OS (aHR 0.65, 95% CI 0.56-0.77). Concerning the extent of surgery, both subgroups exhibited a superior OS outcome associated with upfront surgery (exclusive total laryngopharyngectomy group: aHR 0.54, 95% CI 0.39-0.75; total/partial laryngopharyngectomy group: aHR 0.71, 95% CI 0.59-0.84).</p><p><strong>Conclusions and relevance: </strong>The results demonstrated that upfront surgery showed better OS and DFS than concurrent chemoradiation and remind the clinicians of the potential reduction in survival outcomes when choosing concurrent chemoradiotherapy as primary treatment.</p>","PeriodicalId":16615,"journal":{"name":"Journal of Otolaryngology - Head & Neck Surgery","volume":"53 ","pages":"19160216241293633"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142522172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Stapedectomy: A Retrospective Review of Surgical Results Using a Cold Steel Technique and Pre-Operative CT Correlates. 原发性镫骨切除术:使用冷钢技术和术前 CT 相关性对手术结果的回顾性研究。
IF 2.6 3区 医学
Journal of Otolaryngology - Head & Neck Surgery Pub Date : 2024-01-01 DOI: 10.1177/19160216241288813
Thomas J Hudson, Tamara Mijovic, Jamie M Rappaport
{"title":"Primary Stapedectomy: A Retrospective Review of Surgical Results Using a Cold Steel Technique and Pre-Operative CT Correlates.","authors":"Thomas J Hudson, Tamara Mijovic, Jamie M Rappaport","doi":"10.1177/19160216241288813","DOIUrl":"https://doi.org/10.1177/19160216241288813","url":null,"abstract":"<p><strong>Importance: </strong>Stapedectomy is an effective treatment option for patients with symptomatic otosclerosis. A common surgical technique today is laser stapedotomy, although the equipment required adds a significant cost to the procedure and may not be available in certain, particularly remote, centers. This study aimed to evaluate cold steel stapedectomy in a modern otology practice as a cost-effective and versatile alternative.</p><p><strong>Objective: </strong>The primary objective was to evaluate the efficacy and safety of cold steel stapedectomy. The secondary objectives included characterizing the prevalence of relevant computed tomography (CT) findings and evaluating other factors such as piston size.</p><p><strong>Design: </strong>A retrospective case series from April 2006 to November 2021.</p><p><strong>Setting: </strong>A single tertiary care hospital in Montreal, QC, Canada.</p><p><strong>Participants: </strong>Patients with suspected otosclerosis and no prior stapes surgery.</p><p><strong>Intervention: </strong>Cold steel primary stapedectomy.</p><p><strong>Main outcome measures: </strong>In primary analysis, change in pure tone thresholds, pure tone average (PTA), and complication rates were obtained. Secondary analysis measures included rates of relevant CT findings and change in PTA with piston size.</p><p><strong>Results: </strong>A total of 302 cases were included in the analysis. The average change in air conduction PTA was a decrease of 27 dB, with 91% (276/302) having over 10 dB of improvement. The air-bone gap was closed to within 10 dB in 82% (248/302) of cases and within 20 dB in 96% (290/302) of cases. Overclosure occurred in 19% of cases, while only 4% resulted in worsened PTA bone conduction thresholds. In secondary analysis, 74% of CT scans demonstrated radiologic otosclerosis. Other findings included suspected superior semicircular canal dehiscence in 1.8%.</p><p><strong>Conclusion: </strong>Cold steel stapedectomy was demonstrated to be a safe and effective technique, with audiometric results comparable to laser and drill studies in recent literature. It should be considered as a cost-effective and global health accessible alternative. Additionally, CT scans can provide valuable information in the pre-operative workup.</p>","PeriodicalId":16615,"journal":{"name":"Journal of Otolaryngology - Head & Neck Surgery","volume":"53 ","pages":"19160216241288813"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic Factors of Hearing Improvement for EES and MES in Attic Cholesteatoma. 房角胆脂瘤患者听力改善的 EES 和 MES 预后因素
IF 2.6 3区 医学
Journal of Otolaryngology - Head & Neck Surgery Pub Date : 2024-01-01 DOI: 10.1177/19160216241286794
Minqian Gao, Nan Zeng, Weibiao Kang, Yong Lin, Peng Li, Yuan Tao, Yongtian Lu, Wei Zhao, Xiangwei Chen, Zebin Jiang, Jinliang Gao, Youjun Yu, Wanshan Liang, Sijia Zhai, Qiong Yang, Haidi Yang
{"title":"Prognostic Factors of Hearing Improvement for EES and MES in Attic Cholesteatoma.","authors":"Minqian Gao, Nan Zeng, Weibiao Kang, Yong Lin, Peng Li, Yuan Tao, Yongtian Lu, Wei Zhao, Xiangwei Chen, Zebin Jiang, Jinliang Gao, Youjun Yu, Wanshan Liang, Sijia Zhai, Qiong Yang, Haidi Yang","doi":"10.1177/19160216241286794","DOIUrl":"10.1177/19160216241286794","url":null,"abstract":"<p><strong>Objective: </strong>The surgical strategy of cholesteatomas is still controversial. This study aimed to compare the hearing improvement and determine the prognostic factors between endoscopic and microscopic ear surgery for attic cholesteatoma via a multicenter retrospective study.</p><p><strong>Methods: </strong>This retrospective study included 169 patients with attic cholesteatoma who received endoscopic ear surgery (EES) or microscopic ear surgery (MES) from 12 otorhinolaryngology centers. Hearing improvement between EES and MES was evaluated, including the postoperative pure tone average (PTA) and air-bone gap (A-B Gap), as well as the hearing threshold across the low-, mid-, and high-frequency. The success rate of grafts was collected. Linear regression was performed to access the prognostic value of preoperative PTA and A-B Gap. Patients were followed up for at least 3 years.</p><p><strong>Results: </strong>The graft success rate of EES was 89.66% (78/87) versus 80.49% (66/82) for MES. The postoperative PTA and A-B Gap demonstrated significant improvement in EES compared to MES (Post-PTA: <i>t</i> = 3.281, <i>P</i> = .001; Post-A-B Gap: <i>t</i> = 2.197, <i>P</i> = .029). In the EES group, there were 59 ears (67.82%) with a postoperative A-B Gap ≤20 dB HL, which revealed a higher rate of successful hearing outcomes in EES as opposed to MES (χ<sup>2</sup> = 9.904, <i>P</i> = .019). There were significantly better hearing improvement, shorter surgical times, and lower hospital stays in EES for epitympanic cholesteatoma without stapes superstructure involvement. The preoperative AC ≤79 dB and/or preoperative A-B Gap ≤52 dB was associated with a better prognosis in EES for epitympanic cholesteatoma with stapes superstructure involvement.</p><p><strong>Conclusions: </strong>EES showed higher graft success rate, better hearing improvement, shorter surgical times and hospital stays for attic cholesteatoma, particularly without stapes superstructure involvement. The range of preoperative PTA and A-B Gap have shown the prognostic value, which maybe a favorable surgical indication for EES or MES.</p>","PeriodicalId":16615,"journal":{"name":"Journal of Otolaryngology - Head & Neck Surgery","volume":"53 ","pages":"19160216241286794"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信