Journal of Orthopaedic Surgery最新文献

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Efficacy of adding infiltration between the popliteal artery and the capsule of the posterior knee (IPACK) to adductor canal block and local infiltration analgesia in total knee arthroplasty: A retrospective cohort study. 在全膝关节置换术中,在内收肌管阻滞和局部浸润镇痛的基础上增加腘动脉与膝关节后囊之间的浸润(IPACK)的疗效:一项回顾性队列研究。
IF 1.6 4区 医学
Journal of Orthopaedic Surgery Pub Date : 2024-05-01 DOI: 10.1177/10225536241265445
Dongmei Zhao, Pengcheng Li
{"title":"Efficacy of adding infiltration between the popliteal artery and the capsule of the posterior knee (IPACK) to adductor canal block and local infiltration analgesia in total knee arthroplasty: A retrospective cohort study.","authors":"Dongmei Zhao, Pengcheng Li","doi":"10.1177/10225536241265445","DOIUrl":"10.1177/10225536241265445","url":null,"abstract":"<p><strong>Objective: </strong>Local infiltration analgesia (LIA), adductor canal block (ACB), and infiltration between the popliteal artery and the capsule of the posterior knee (IPACK) are popular multimodal analgesia techniques used during total knee arthroplasty (TKA). This study aimed to explore the efficacy of adding the IPACK technique to ACB and LIA in patients undergoing TKA.</p><p><strong>Methods: </strong>In this retrospective cohort study, patients who underwent primary unilateral TKA were divided into two groups based on their date of admission. Sixty-three patients underwent IPACK, ACB and LIA (IPACK group) during surgery, while 60 patients underwent ACB and LIA (control group). The primary outcome was the postoperative administration of morphine hydrochloride as a rescue analgesic. Secondary outcomes included time to first rescue analgesia, postoperative pain assessed using the visual analog scale (VAS), functional recovery assessed by knee range of motion and ambulation distance, time until hospital discharge, and complication rates.</p><p><strong>Results: </strong>The two groups were similar in average postoperative 0-to-24-h morphine consumption (11.8 mg for the control group vs 12.7 mg for the IPACK group, <i>p</i> = .428) and average total morphine consumption (18.2 mg vs 18.0 mg, <i>p</i> = .983) during hospitalization. There were also no significant differences in the secondary outcomes.</p><p><strong>Conclusions: </strong>The addition of IPACK to ACB and LIA did not provide any clinical analgesic benefits. Orthopedic surgeons and anesthesiologists are justified in using ACB and LIA without IPACK for TKA.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"32 2","pages":"10225536241265445"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141427020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomechanical study of 3D-printed titanium alloy pad for repairing glenoid bone defect. 用于修复盂骨缺损的 3D 打印钛合金垫的生物力学研究。
IF 1.6 4区 医学
Journal of Orthopaedic Surgery Pub Date : 2024-05-01 DOI: 10.1177/10225536241257169
Danlei Huang, Jun Wang, Zhiyang Ye, Feixiong Chen, Haoyuan Liu, Jianming Huang
{"title":"Biomechanical study of 3D-printed titanium alloy pad for repairing glenoid bone defect.","authors":"Danlei Huang, Jun Wang, Zhiyang Ye, Feixiong Chen, Haoyuan Liu, Jianming Huang","doi":"10.1177/10225536241257169","DOIUrl":"10.1177/10225536241257169","url":null,"abstract":"<p><p><b>Background:</b> The purpose of this study was to investigate the effect of 3D-printed technology to repair glenoid bone defect on shoulder joint stability. <b>Methods:</b> The shoulder joints of 25 male cadavers were tested. The 3D-printed glenoid pad was designed and fabricated. The specimens were divided into 5 groups. Group A: no bone defect and the structure of the glenoid labrum and joint capsule was intact; Group B: Anterior inferior bone defect of the shoulder glenoid; Group C: a pad with a width of 2 mm was installed; Group D: a pad with a width of 4 mm was installed; Group E: a pad with a width of 6 mm was installed. This study measured the distance the humeral head moved forward at the time of glenohumeral dislocation and the maximum load required to dislocate the shoulder. <b>Results:</b> The shoulder joint stability and humerus displacement was significantly lower in groups B and C compared with group A (<i>p</i> < .05). Compared with group A, the stability of the shoulder joint of group D was significantly improved (<i>p</i> < .05). However, there was no significant difference in humerus displacement between groups D and A (<i>p</i> > .05). In addition, compared with group A, shoulder joint stability was significantly increased and humerus displacement was significantly decreased in group E (<i>p</i> < .05). <b>Conclusion:</b> The 3D-printed technology can be used to make the shoulder glenoid pad to perfectly restore the geometric shape of the shoulder glenoid articular surface. Moreover, the 3D-printed pad is 2 mm larger than the normal glenoid width to restore the initial stability of the shoulder joint.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"32 2","pages":"10225536241257169"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141070856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discrepancies in plantar pressure distribution between affected and unaffected sides in patients with plantar fasciitis. 足底筋膜炎患者患侧与非患侧足底压力分布的差异。
IF 1.6 4区 医学
Journal of Orthopaedic Surgery Pub Date : 2024-05-01 DOI: 10.1177/10225536241258331
Min Gyu Kyung, Dong-Oh Lee, Kihyun Moon, Young Sik Yoon, Dong Yeon Lee
{"title":"Discrepancies in plantar pressure distribution between affected and unaffected sides in patients with plantar fasciitis.","authors":"Min Gyu Kyung, Dong-Oh Lee, Kihyun Moon, Young Sik Yoon, Dong Yeon Lee","doi":"10.1177/10225536241258331","DOIUrl":"10.1177/10225536241258331","url":null,"abstract":"<p><strong>Purpose: </strong>A fundamental understanding of plantar pressure distribution is important for prescribing an appropriate orthosis and applying nonoperative methods, such as stretching exercises, for the treatment of plantar fasciitis. Despite existing research on plantar pressure distribution, discrepancies between affected and unaffected sides in unilateral plantar fasciitis patients warrant further investigation. This study aimed to evaluate the plantar pressure distribution in patients with unilateral plantar fasciitis by comparing it with that on the contralateral unaffected side.</p><p><strong>Methods: </strong>We retrospectively reviewed records from 20 consecutive patients diagnosed with unilateral plantar fasciitis, using the unaffected side as the control. The emed<sup>®</sup> pedobarographic system was used to measure the plantar pressure distribution during gait. The analysis was performed using a 4-mask configuration (toes, forefoot, midfoot, and hindfoot).</p><p><strong>Results: </strong>Both sides showed no significant differences in radiographic parameters. The affected side showed a significantly higher contact area, maximum force, and force-time integrals in the midfoot. However, the unaffected side demonstrated significantly higher maximum force and force-time integrals in the hindfoot. There was no difference in the distribution of the peak pressure and pressure-time integrals between the two sides in all mask regions. The increased contact area and maximum force in the midfoot on the side with plantar fasciitis may result from heel pain-induced weight transfer from the hindfoot.</p><p><strong>Conclusion: </strong>The findings of this study provide a basic understanding of plantar pressure distribution in the treatment of plantar fasciitis and highlight the importance of considering inter-side differences when designing treatment interventions or orthotic devices.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"32 2","pages":"10225536241258331"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141175736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of risk factors and clinical outcomes for symmetric peripheral gangrene: A new scoring system using a common data model database. 识别对称性外周坏疽的风险因素和临床结果:使用通用数据模型数据库的新评分系统。
IF 1.6 4区 医学
Journal of Orthopaedic Surgery Pub Date : 2024-05-01 DOI: 10.1177/10225536241276892
Maria Florencia Deslivia, Do-Hoon Kim, Suk-Joong Lee, Hee-June Kim, Erica Kholinne, Hyun-Joo Lee
{"title":"Identification of risk factors and clinical outcomes for symmetric peripheral gangrene: A new scoring system using a common data model database.","authors":"Maria Florencia Deslivia, Do-Hoon Kim, Suk-Joong Lee, Hee-June Kim, Erica Kholinne, Hyun-Joo Lee","doi":"10.1177/10225536241276892","DOIUrl":"10.1177/10225536241276892","url":null,"abstract":"<p><p><b>Background:</b> Symmetrical peripheral gangrene (SPG) is a destructive clinical condition where amputation is often the final treatment option. We aimed to identify the predictors of SPG using the common data model (CDM) and propose a new scoring system for predicting hospitalized patients at risk of developing SPG. <b>Methods:</b> A cohort of patients treated with intravenous noradrenaline, epinephrine, and vasopressin between 2011 and 2020 was retrospectively analyzed using the CDM database. The main outcome was amputation performed as a resuscitation measure. We investigated risk factors including demographic characteristics, comorbidities, and preoperative laboratory values. Based on demographic variables such as age and sex, a 1:10 propensity score matching (PSM) was performed. The odds ratio (OR) was calculated using logistic regression analysis. <b>Results:</b> Amputation was performed in 308 (0.4%) patients out of a cohort of 73,902 patients. Age, sex, hypertension, diabetes mellitus (DM), renal disease (RD), heart failure, anemia, hypercholesterolemia, peripheral vascular disease (PVD), and laboratory markers such as albumin, eosinophils, hematocrit, lymphocytes, monocytes, neutrophils, ESR, aPTT, creatinine, and BUN were statistically significant. Logistic regression analysis revealed statistically significant differences in DM (OR 5.51), RD (OR 2.90), PVD (OR 9.67), and cerebrovascular disease (CVD) (OR 0.49). Compared to the group without amputation, logistic regression analysis after matching the age and sex group with 1:10 PSM showed statistically significant results in DM (OR 3.59), RD (OR 2.59), PVD (OR 7.76), and CVD (OR 0.40). <b>Conclusion:</b> Early recognition of high-risk patients may help medical providers prevent severe outcomes, including amputation surgery.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"32 2","pages":"10225536241276892"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Finite element analysis of the effect of tibial osteotomy on the stress of polyethylene liner in total knee arthroplasty. 全膝关节置换术中胫骨截骨对聚乙烯衬垫应力影响的有限元分析。
IF 1.6 4区 医学
Journal of Orthopaedic Surgery Pub Date : 2024-05-01 DOI: 10.1177/10225536241251926
Lihui Sun, Yu Han, Zheng Jing, Dongbo Li, Jianguo Liu, Dongsong Li
{"title":"Finite element analysis of the effect of tibial osteotomy on the stress of polyethylene liner in total knee arthroplasty.","authors":"Lihui Sun, Yu Han, Zheng Jing, Dongbo Li, Jianguo Liu, Dongsong Li","doi":"10.1177/10225536241251926","DOIUrl":"10.1177/10225536241251926","url":null,"abstract":"<p><strong>Aim: </strong>To explore the effects of tibial osteotomy varus angle combined with posterior tibial slope (PTS) on the stress of polyethylene liner in total knee arthroplasty (TKA) by building finite element model (FEM).</p><p><strong>Methods: </strong>Established the FEM of standard TKA with tibial osteotomy varus angle 0° to 9° were established and divided into 10 groups. Next, each group was created 10 FEMs with 0° to 9° PTS separately. Calculated the stress on polyethylene liner in each group in Abaqus. Finally, the relevancy between tibial osteotomy angle and polyethylene liner stress was statistically analyzed using multiple regression analysis.</p><p><strong>Results: </strong>As the varus angle increased, the area of maximum stress gradually shifted medially on the polyethylene liner. As the PTS increases, the percentage of surface contact forces on the medial and lateral compartmental of the polyethylene liner gradually converge to the same. When the varus angle is between 0° and 3°, the maximum stress of the medial compartmental surfaces of polyethylene liner rises smoothly with the increase of the PTS. When the varus angle is between 4° and 9°, as the increase of the PTS, the maximum stress of polyethylene liner rises first and then falls, forming a trough at PTS 5° and then rises again. Compared to the PTS, the varus angle has a large effect on the maximum stress of the polyethylene liner (<i>p</i> < .001).</p><p><strong>Conclusion: </strong>When the varus angle is 0° to 3°, PTS 0° is recommended, which will result in a more equalized stress distribution of the polyethylene liner in TKA.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"32 2","pages":"10225536241251926"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140908998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A modified "outside-in" Broström-Gould procedure yielding favorable outcomes for the management of chronic lateral ankle instability-a retrospective study with mid-term follow-up. 改良 "外入式 "布罗斯特伦-古尔德手术治疗慢性外侧踝关节不稳取得良好疗效--一项中期随访的回顾性研究。
IF 1.6 4区 医学
Journal of Orthopaedic Surgery Pub Date : 2024-05-01 DOI: 10.1177/10225536241257760
Guolei Zhang, Wenqing Li, Haibo Yao, Rongzhi Tan, Chuyan Li
{"title":"A modified \"outside-in\" Broström-Gould procedure yielding favorable outcomes for the management of chronic lateral ankle instability-a retrospective study with mid-term follow-up.","authors":"Guolei Zhang, Wenqing Li, Haibo Yao, Rongzhi Tan, Chuyan Li","doi":"10.1177/10225536241257760","DOIUrl":"10.1177/10225536241257760","url":null,"abstract":"<p><p><b>Purpose:</b> There are various surgical interventions available for the management of Chronic lateral ankle instability (CLAI). The Broström-Gould procedure has gained widespread recognition among foot and ankle specialists for its favorable surgical outcomes. However, with advancements in anatomical understanding and medical technology, further enhancements to the effectiveness of the Gould procedure are warranted. This study introduces a all-inside modified \"outside-in\" Broström -Gould procedure as an alternative approach for addressing lateral ankle instability. <b>Methods:</b> From August 2020 to October 2022, 40 patients with lateral ankle instability who underwent arthroscopic repair of the modified \"outside-in\" Broström-Gould procedure were retrospectively analyzed. All patients received standard non-surgical treatment before surgery for more than 6 months without symptom relief. Visual Analogue Scale (VAS) and American Orthopaedic Foot and Ankle Society (AOFAS) and Karlsson-Peterson score were used to evaluate the postoperative effect. <b>Results:</b> All patients were followed up for (14.62 ± 2.04) months. One year after operation, all patients could walk normally, ankle instability sensation disappeared, varus stress test and anterior drawer test were negative. The VAS , AOFAS and Karlsson-Peterson scores of all patients were significantly better compared with those before operation, and the difference between before and after operation was statistically significant. <b>Conclusions:</b> The modified \"outside-in\" Broström-Gould procedure can effectively treat CLAI, which can obtain satisfactory results. The procedure is straightforward, the impact is minimal, and the aesthetics are pleasing.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"32 2","pages":"10225536241257760"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Daprodustat reduces skeletal muscle ischemia-reperfusion injury in mice. 达泊司他:减轻小鼠骨骼肌缺血再灌注损伤
IF 1.6 4区 医学
Journal of Orthopaedic Surgery Pub Date : 2024-05-01 DOI: 10.1177/10225536241267725
Weiqiang Wu, Yongfa Zhang, Ying Zhang, Jiuyun Zhang, Renbin Li, Tie Ke
{"title":"Daprodustat reduces skeletal muscle ischemia-reperfusion injury in mice.","authors":"Weiqiang Wu, Yongfa Zhang, Ying Zhang, Jiuyun Zhang, Renbin Li, Tie Ke","doi":"10.1177/10225536241267725","DOIUrl":"10.1177/10225536241267725","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the present work was to assess the specific effects and underlying mechanisms of Daprodustat (GSK1278863) on skeletal muscle injury induced by ischemia reperfusion (I/R).</p><p><strong>Methods: </strong>C57BL/6 mice were randomized into the skeletal muscle I/R injury (I/R), Daprodustat (GSK1278863) pretreatment and I/R (I/R + GSK) and sham operation (Sham) groups. The skeletal muscle I/R injury model was established by placing an orthodontic rubber band at the left hip joint for 3 h and releasing it for 3 h. H&E staining, wet weight/dry weight ratio assessment, TUNEL assay, ELISA, qRT-PCR and immunoblot were utilized to assess the effects of Daprodustat.</p><p><strong>Results: </strong>Daprodustat pretreatment significantly ameliorated apoptosis in skeletal muscle cells, reduced oxidative damage and suppressed inflammatory cytokines. Mechanistically, Daprodustat positively affected NF-κB signaling activation.</p><p><strong>Conclusion: </strong>These data demonstrated that Daprodustat may provide a potential clinical approach for preventing or treating skeletal muscle injury induced by I/R.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"32 2","pages":"10225536241267725"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141766374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomechanical and histological evaluation of aspirin in rotator cuff tear rat model. 阿司匹林对肩袖撕裂大鼠模型的生物力学和组织学评估
IF 1.6 4区 医学
Journal of Orthopaedic Surgery Pub Date : 2024-05-01 DOI: 10.1177/10225536241265827
Seok Won Chung, Seung Ho Chung, Dong-Hyun Kim, Hyun Joo Lee, Eugene J Park, Bum-Jin Shim, Chul-Hyun Cho, Jong Pil Yoon
{"title":"Biomechanical and histological evaluation of aspirin in rotator cuff tear rat model.","authors":"Seok Won Chung, Seung Ho Chung, Dong-Hyun Kim, Hyun Joo Lee, Eugene J Park, Bum-Jin Shim, Chul-Hyun Cho, Jong Pil Yoon","doi":"10.1177/10225536241265827","DOIUrl":"10.1177/10225536241265827","url":null,"abstract":"<p><p><b>Background:</b> Aspirin is a representative non-steroidal anti-inflammatory drug (NSAIDs) and has been commonly used for the treatment of tendinopathy in clinical practice. In this study, we aimed to evaluate the biomechanical and histological healing effects of aspirin on the healing of the tendon-to-bone interface after rotator cuff tear repair. <b>Methods:</b> A total of 20 male Sprague-Dawley rats were randomly divided into two groups of 10 rats each. Group-C performed repaironly, and group-aspirin treated with aspirin after tendon repair. Group-aspirin rat were intraperitoneally injected with aspirin at 10 mg/kg every 24 h for 7 days. Eight weeks after surgery, the left shoulder of each rat was used for histological analysis and the right shoulder for biomechanical analysis. <b>Results:</b> In the biomechanical analysis, there was no significant difference in load-to-failure (group-C: 0.61 ± 0.32 N, group-aspirin: 0.74 ± 0.91 N; <i>p</i> = .697) and ultimate stress (group-C: 0.05 ± 0.01 MPa, group-aspirin: 0.29 ± 0.43 MPa; <i>p</i> = .095). For the elongation (group-C: 222.62 ± 57.98%, group-aspirin: 194.75 ± 75.16%; <i>p</i> = .028), group-aspirin confirmed a lower elongation level than group-C. In the histological evaluation, the Bonar score confirmed significant differences in collagen fiber density (group-C: 1.60 ± 0.52, group-aspirin: 2.60 ± 0.52, <i>p</i> = .001) and vascularity (group-C: 1.00 ± 0.47, group-aspirin: 2.20 ± 0.63, <i>p</i> = .001) between the groups. <b>Conclusions:</b> Aspirin injection after rotator cuff tear repair may enhance the healing effect during the early remodeling phase of tendon healing.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"32 2","pages":"10225536241265827"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141875122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inadequate anticoagulation and hyperuricemia cause knee pain after platelet-rich plasma injection: A retrospective study. 抗凝不足和高尿酸血症导致血小板丰富血浆注射后膝关节疼痛:一项回顾性研究。
IF 1.6 4区 医学
Journal of Orthopaedic Surgery Pub Date : 2024-05-01 DOI: 10.1177/10225536241277604
Yang Chen, Hongxun Sang, Song Wu, Haobin Zhang, Yi Zhang, Hongxing Li
{"title":"Inadequate anticoagulation and hyperuricemia cause knee pain after platelet-rich plasma injection: A retrospective study.","authors":"Yang Chen, Hongxun Sang, Song Wu, Haobin Zhang, Yi Zhang, Hongxing Li","doi":"10.1177/10225536241277604","DOIUrl":"10.1177/10225536241277604","url":null,"abstract":"<p><strong>Objectives: </strong>Platelet-rich plasma treatment delays the need for total knee replacement in patients with knee osteoarthritis. However, its use and preparation remain controversial. The aim of this study was to investigate the relationship between anticoagulant use in the preparation of platelet-rich plasma and post-treatment pain in patients with knee osteoarthritis. Additionally, we explored the efficacy of platelet-rich plasma over medium- and long-term follow-up periods and identified other factors that may affect treatment outcomes.</p><p><strong>Methods: </strong>In this retrospective study, 225 patients with knee osteoarthritis, who underwent knee platelet-rich plasma treatment from June 2021 to January 2022, were examined at three study centres. Patients were categorised, based on the type and amount of anticoagulant used during platelet-rich plasma preparation, into 4% sodium citrate (SC) 0.6 mL, 4% SC 1 mL, 4% SC 2 mL, heparin 0.1 mL, and heparin 0.2 mL groups. We analysed the patients' basic information, pain after treatment, and inflammatory markers (i.e., interleukin 6, tumour necrosis factor-α, and hypersensitive C-reactive protein) in the joint fluid via enzyme-linked immunosorbent assay and joint fluid crystallisation. Additionally, we assessed the patients' Western Ontario and McMaster University scores and minimal clinically significant differences after treatment.</p><p><strong>Results: </strong>Patients in the 4% SC 0.6 mL and heparin 0.1 mL groups experienced less pain after platelet-rich plasma treatment than did patients in the high-dose anticoagulant group. The joint fluid of patients with pain in these groups had lower levels of inflammatory markers. Patients treated with SC had slightly better medium- and long-term therapeutic outcomes than did patients treated with heparin. Patients with poorly controlled hyperuricemia also experienced pain after platelet-rich plasma treatment.</p><p><strong>Conclusions: </strong>The results suggest that platelet-rich plasma prepared using high-dose anticoagulants or administered to patients with poorly controlled hyperuricaemia may lead to moderate-to-severe knee pain and joint effusion after joint puncture therapy. Platelet-rich plasma had a therapeutic effect on knee osteoarthritis; however, its efficacy gradually decreased over time. SC anticoagulant is more suitable for platelet-rich plasma preparation than is heparin. Further studies are needed to understand the safety and the various factors influencing platelet-rich plasma therapy.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"32 2","pages":"10225536241277604"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A matching and localization study of iliac bone graft for repair of talar cartilage injury secondary to lateral ankle instability. 髂骨移植修复因外侧踝关节不稳而继发的距骨软骨损伤的匹配和定位研究。
IF 1.6 4区 医学
Journal of Orthopaedic Surgery Pub Date : 2024-05-01 DOI: 10.1177/10225536241273979
Qiang Zhao, Zhouhu Zhang, Xiaohui Gu
{"title":"A matching and localization study of iliac bone graft for repair of talar cartilage injury secondary to lateral ankle instability.","authors":"Qiang Zhao, Zhouhu Zhang, Xiaohui Gu","doi":"10.1177/10225536241273979","DOIUrl":"10.1177/10225536241273979","url":null,"abstract":"<p><p><b>Background:</b> To investigate the search for an Iliac-Talar Grafts on the iliac bone that is morphologically matched to a multiplanar injury lesion of the talus; while utilizing a bone-harvesting guide to ensure precise positioning of the Iliac-Talar Grafts. <b>Methods:</b> A total of twenty-two cases with both talar CT data and iliac CT data were collected from January 2019 to June 2023. One case each of talar deformity injury and bone disease were excluded, resulting in a selection of 20 cases. The medial and lateral target repair areas of the talus were formulated, and virtual surgery was performed by using digital orthopedic technology to locate an iliac-talar restoration on the iliac bone that matched the morphology of the multiplanar injury lesion of the talus. 3D chromatographic deviation analysis was used to assess the accuracy of Iliac-Talar Grafts in terms of morphometric matching and positioning, while personalized iliac bone extraction guides were designed to ensure accurate positioning of the Iliac-Talar Grafts. <b>Results:</b> The best fitting point for repairing the medial talar lesion is determined to be medial to the anterior iliac crest, specifically 2.935 ± 0.365 cm posterior to the anterior superior iliac spine, and 2.550 ± 0.559 cm anterior to the valgus-iliac crest point (VICP). Similarly, for the repair of the lateral talar lesion, the ideal position is found to be lateral to the posterior iliac crest, approximately 2.695 ± 0.640 cm posterior to the valgus-iliac crest point (VICP). Utilizing bone extraction guides enables precise positioning for iliac bone extraction. <b>Conclusion:</b> This study utilizes virtual surgery, 3D chromatographic deviation analysis, and guide plate techniques in digital orthopedics to precisely locate the Iliac-Talar Graft on the iliac bone, matching the morphology of the talar lesion; it provides a new solution for cutting the iliac bone implant that matches the the multifaceted talar lesion to be repaired.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"32 2","pages":"10225536241273979"},"PeriodicalIF":1.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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