Journal of Microbiology and Infectious Diseases最新文献

{"title":"Miliary Tuberculosis Mimicking Multiple Myeloma: A Rare Case","authors":"J. Kaur, T. Raju, Y. Cheema, Jasmin Singh","doi":"10.5799/jmid.1130152","DOIUrl":"https://doi.org/10.5799/jmid.1130152","url":null,"abstract":"Miliary tuberculosis or disseminated tuberculosis is one of India's most typical forms of tuberculosis. It can have varied presentations, from classical pulmonary disease to affection of extra-pulmonary sites, the most common being the vertebral column. With a wide array of clinical manifestations, differentiating disseminated tuberculosis from common malignancies is no less than a herculean task for a clinician. Keeping a high index of clinical suspicion and detailed work up in the right direction can save the clinician and the patient from an exhaustive ordeal of futile investigations. Here, we present a rare case of miliary tuberculosis masquerading as a common malignancy of the elderly, re-emphasizing the need for a systematic approach to such confusing presentations.","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76993589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Floral Differences of Conjunctiva in Patients with Renal Diseases","authors":"L. Aslan, S. Kocturk, M. Gül, M. Aslankurt, O. Altunoren","doi":"10.5799/jmid.1130130","DOIUrl":"https://doi.org/10.5799/jmid.1130130","url":null,"abstract":"Objectives: This study aimed to evaluate whether conjunctival flora is different in patients with chronic renal disease (CR) among its subgroups and healthy subjects. \u0000Methods: A total of 105 adult CR patients; 35 hemodialysis (HD), 35 diabetic hemodialysis (DHD), 35 renal transplantation (RT), and 40 healthy subjects were enrolled. After ophthalmologic examination, a swab was taken from the lower fornix of the right eye using a cotton-tipped applicator and directly sub-cultured on 5% sheep’s blood agar, chocolate agar, and eosin methylene blue agar. Differences in both bacterial growth and flora diversity of the groups were compared. \u0000Results: The order of bacterial growth rates in the groups are RT 65%), DHD (57%), HD (56%), and control (48%). The RT group had a statistically significant difference from the control group (p","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73014538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic Susceptibility and Plasmid Profile of Multidrug resistant Uropathogenic Serratia marcescens","authors":"B. U. Nmesirionye, Chukwudi T. Ugwu, K. Nworie","doi":"10.5799/jmid.1085914","DOIUrl":"https://doi.org/10.5799/jmid.1085914","url":null,"abstract":"","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84308811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MecA and ermA Gene Discrepancy from Their Phenotypic Profile in Staphylococcus aureus Isolates","authors":"Shreya Mahesh, Rajkumar Kalyan, P. Gupta, Sheetal Veram, V. Venkatesh, P. Tripathi","doi":"10.5799/jmid.1085907","DOIUrl":"https://doi.org/10.5799/jmid.1085907","url":null,"abstract":"","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"1221 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77679679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular Detection of Leptospira in Pediatric Aseptic Meningitis","authors":"A. Mohamed, Sami E. A Algam, K. Enan, A. R. E. El Hussein, I. Elkhidir","doi":"10.5799/jmid.1086212","DOIUrl":"https://doi.org/10.5799/jmid.1086212","url":null,"abstract":"","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81827414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malaria and COVID-19 in an Indigenous Patient, Overlapping of Two Febrile Illnesses","authors":"I. Suarez, R. Giner, Diana De Oliveira, Marcel Yibirin","doi":"10.5799/jmid.1086183","DOIUrl":"https://doi.org/10.5799/jmid.1086183","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is an illness caused by a novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Malaria is a parasitic infection caused by the parasite genus Plasmodium. We present the case of a 69-year-old male indigenous patient from Amazonas, Venezuela, who complained of fever, cough, loss of taste and smel l, and diarrhea. A SARS-CoV-2 PCR test was positive, and treatment was started. However, over the next few days, his condition worsened. In addition to his previous symptoms, the patient reported profuse sweating accompanied by fever and myalgia. Therefore, a blood smear and ELISA were performed, which were positive for Plasmodium falciparum, for which treatment with antimalarial agents was also started. [ FROM AUTHOR] Copyright of Journal of Microbiology & Infectious Diseases is the property of Journal of Microbiology & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81245016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arthritogenic Arbovirus in Madagascar: State and Epidemic Risk","authors":"Rakotomalala Ni̇ari̇antsoa, Rakotomalala Hoby Nomena, Rakotoson Juli̇en, R. Antsa, Ranaivoarison Veroni̇que, Ralandison Stéphane","doi":"10.5799/jmid.1085937","DOIUrl":"https://doi.org/10.5799/jmid.1085937","url":null,"abstract":"","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83401971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of B.1.617.2 (Delta) Variant of SARS-CoV-2","authors":"Mohd Fardeen Husain Shahanshah, Saloni Jain, Bhawna Sharma, Ananya Grewall, S. Swami","doi":"10.5799/jmid.1086226","DOIUrl":"https://doi.org/10.5799/jmid.1086226","url":null,"abstract":"The emergence of numerous variants of SARS-CoV-2 has caused massive setbacks and prolonged the COVID-19 pandemic. Some of the variants are still under investigation, while some have become a reason of grave concern. One such variant is B.1.617.2, known as the Delta variant, which was first detected in India. A comprehensive analysis and comparison of this particular variant have been done to the original Wuhan strain, and the possible reasons behind rapid mutation have also been discussed. A comprehensive literature search was done to summarize the information on the variants of SARS-CoV-2 and the reasons behind their mutation, with a significant focus on the B.1.617.2 variant. Data were collected from various online sources such as PubMed, Google Scholar, MEDLINE, Worldometer, WHO, CDC, and GISAID. In addition, 3D structures of spike proteins were obtained from Protein Data Bank (PDB). The data shows that the spike protein of the B.1.617.2 strain is highly mutated and has accumulated eight amino acid changes. Besides spike protein, changes in non-structural proteins (nsP2, nsP3, nsP4, nsP12, and nsP15), other structural proteins (nucleocapsid and membrane protein), and accessory proteins (ns3, ns7a) have been observed as well. Furthermore, in almost all the variants of SARS-CoV-2, D614G mutation occurs, suggesting its role in increased infectivity and transmission. New variants are continuously emerging on which we have no control. Spike mutations are more favored and essential in the evolution of new variants because it increases the transmissibility and infectivity of the virus. Therefore, to maximally protect public health, knowledge of different variants is essential. [ FROM AUTHOR] Copyright of Journal of Microbiology & Infectious Diseases is the property of Journal of Microbiology & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82762327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vertical Virus Transmission from SARS-CoV-2-positive Mothers to Neonates: A Tertiary Care Hospital Experience","authors":"N. Singh, Nikita Sherwani, Jyoti Jaiswal, Tripti Nagaria, A. Neral, O. Khandwal","doi":"10.5799/jmid.1085903","DOIUrl":"https://doi.org/10.5799/jmid.1085903","url":null,"abstract":"Objectives: The coronavirus disease 2019 (COVID-19) outbreak is evolving rapidly worldwide. However, little is known about the association between pregnant women with COVID-19 and its transmission to neonates. This investigation aimed to see if COVID-19 infection could be transmitted vertically into the uterus. Methods: We conducted a prospective observational study. 48 COVID-19 infected mothers were enrolled during their third trimester. A qRT-PCR assay of the nasal and oropharyngeal swab samples was performed to confirm positive for COVID-19 infection as per WHO protocol. In addition, characteristics of pregnant women with confirmed SARS -CoV-2 infection and newborns were documented. Results: Forty-eight expectant mothers, 10 (20.8%) were found symptomatic, and 38 (79.2%) were asymptomatic, with COVID-19 infection were delivered (33 cesarean section & 15 vaginal deliveries). One female child (4.1%) out of 48 newborns was initially diagnosed with COVID-19 infection based on a nucleic acid qRT-PCR. The female child showed no or negligible signs and recovered completely, whereas 47 neonates (95.9%) confirmed negative. None of the mothers or neonates died from COVID-19 related pulmonary problems. Conclusion: There is insufficient evidence on vertical virologic transmission of COVID-19 infection during the third trimester of pregnancy. Additionally, research and surveillance involving adequate testing of samples of placental tissue, breast milk, vaginal swab, amniotic fluid, and cord blood will be needed to establish the possibility of vertical transmission of infection. [ FROM AUTHOR] Copyright of Journal of Microbiology & Infectious Diseases is the property of Journal of Microbiology & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83868006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostics and Clinical Care of Nocardia Keratitis","authors":"Muna Malik, F. K. Akhtar, K. Bhinder, Z. Sarfraz, A. Ameena, Ali Hashim Zubai̇r, A. Sarfraz, Zubair Saleem","doi":"10.5799/jmid.1086199","DOIUrl":"https://doi.org/10.5799/jmid.1086199","url":null,"abstract":"","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"111 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83454559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}