Encyclopedia of Bioinformatics and Computational Biology最新文献

Evolutionary Models 进化模型

Encyclopedia of Bioinformatics and Computational Biology Pub Date : 2020-09-01 DOI: 10.1201/b11422-23

D. Liberles, B. Holland

引用次数: 7

Intelligent Agents and Environment 智能代理与环境

Encyclopedia of Bioinformatics and Computational Biology Pub Date : 2018-10-04 DOI: 10.1016/B978-0-12-809633-8.20327-0

A. Garro, M. Mühlhäuser, A. Tundis, S. Mariani, Andrea Omicini, Giuseppe Vizzari

引用次数: 4

Intelligent Agents: Multi-Agent Systems 智能代理:多代理系统

Encyclopedia of Bioinformatics and Computational Biology Pub Date : 2018-10-04 DOI: 10.1016/B978-0-12-809633-8.20328-2

A. Garro, M. Mühlhäuser, A. Tundis, M. Baldoni, C. Baroglio, F. Bergenti, Paolo Torroni

引用次数: 15

Engineering of Supramolecular RNA Structures 超分子RNA结构工程

Encyclopedia of Bioinformatics and Computational Biology Pub Date : 2018-09-06 DOI: 10.1016/b978-0-12-809633-8.20442-1

E. Ramlan, M. F. Raih

引用次数: 0

Measurements of Accuracy in Biostatistics 生物统计学准确度的测量

Encyclopedia of Bioinformatics and Computational Biology Pub Date : 2018-09-06 DOI: 10.1016/b978-0-12-809633-8.20355-5

Haiying Wang, Jyotsna Talreja Wassan, Huiru Zheng

引用次数: 1

Vaccine Target Discovery 发现疫苗靶点

Encyclopedia of Bioinformatics and Computational Biology Pub Date : 2018-09-06 DOI: 10.1016/B978-0-12-809633-8.20100-3

L. Chong, Asif M. Khan

引用次数: 16

Protein Structure Classification 蛋白质结构分类

Encyclopedia of Bioinformatics and Computational Biology Pub Date : 2015-10-15 DOI: 10.1002/9780470015902.A0003033.PUB3

N. Dawson, Sayoni Das, J. Lees, C. Orengo

{"title":"Protein Structure Classification","authors":"N. Dawson, Sayoni Das, J. Lees, C. Orengo","doi":"10.1002/9780470015902.A0003033.PUB3","DOIUrl":"https://doi.org/10.1002/9780470015902.A0003033.PUB3","url":null,"abstract":"To understand and map the universe of protein structures, it is necessary to collate, annotate and classify these structures in a rational scheme. While the individual protein structures reveal much about the specific molecular mechanisms that underlie a particular biological function, taken together this body of data also allows biologists to explore the evolution of structure and function. As structure is much better conserved than sequence, these data also facilitate the recognition of evolutionary relationships that are hidden at the sequence level. The different approaches that have been taken to tackle this problem include the identification of protein domains, phylogenetic and phenetic classification and hierarchical and nearest-neighbour clustering. Powerful sequence searching methods then enable structural assignments to be allocated to genomic data. \u0000 \u0000 \u0000 \u0000Key Concepts \u0000 \u0000Proteins comprise recognisable smaller sequence domains. \u0000Domains usually consist of secondary and supersecondary structures and have an average size of 150 ± 50 residues. \u0000These domains may be thought of as units of evolution, which recur in many proteins in various combinations. \u0000Structural classifications have been developed that group domains into fold and sequence families. \u0000The phenetic approach groups the proteins according to their structural characteristics. \u0000The phylogenetic approach groups proteins into families according to their evolutionary history. \u0000 \u0000 \u0000 \u0000 \u0000Keywords: \u0000 \u0000protein structure classification; \u0000common folds; \u0000protein architecture; \u0000structural comparison; \u0000genomes","PeriodicalId":165920,"journal":{"name":"Encyclopedia of Bioinformatics and Computational Biology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125642893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Protein Three-Dimensional Structure Prediction 蛋白质三维结构预测

Encyclopedia of Bioinformatics and Computational Biology Pub Date : 1900-01-01 DOI: 10.1016/b978-0-12-809633-8.20505-0

Sanne Abeln, K. Feenstra, J. Heringa

引用次数: 5

Statistical Inference Techniques 统计推断技术

Encyclopedia of Bioinformatics and Computational Biology Pub Date : 1900-01-01 DOI: 10.1016/B978-0-12-809633-8.20357-9

D. Canditiis

引用次数: 3

Infrastructures for High-Performance Computing: Cloud Computing Development Environments 高性能计算的基础设施:云计算开发环境

Encyclopedia of Bioinformatics and Computational Biology Pub Date : 1900-01-01 DOI: 10.1016/B978-0-12-809633-8.20375-0

F. Marozzo, Paolo Trunfio

引用次数: 0