Journal of Medicinal Plants最新文献

{"title":"Cytotoxic activity of Centaurea albonitens Turrill aerial parts in colon and breast cancer cell lines","authors":"S. Esmaeili, M. Asadi, M. Mosaddegh, Saeed Mohammadi Motamed, M. Hamzeloo-Moghadam","doi":"10.52547/jmp.20.78.59","DOIUrl":"https://doi.org/10.52547/jmp.20.78.59","url":null,"abstract":"MTT, 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; MCF-7, Breast cancer cell line; HT-29, Human colorectal adenocarcinoma cell line Background: Cancer is the second cause of death in developed countries. Colon and breast cancers are among the most prevalent ones. Research focusing on finding new natural products with fewer side effects to fight cancer is increasing. Objectives: The present study aimed to evaluate the cytotoxicity of Centaurea albonitens Turrill methanol extract and its fractions against colon and breast cancer cell lines and a normal cell line of bovine kidney cells. Methods: The methanol extract and petroleum ether, chloroform and aqueous fractions were provided from the aerial parts of C. albonitens by maceration method in three days. Each day the solvent was refreshed. Colon (HT-29) and breast (MCF-7) cell lines were treated with the extract/fractions for 48 h for evaluating the cytotoxic activity by MTT assay. The apoptotic induction potential was also evaluated with the Hoechst 33258 staining method. Results: The most considerable effect was reported from the chloroform fraction with IC 50 values of 25.6 and 25.1 μg/mL in MCF-7 and HT-29 cells, respectively. In Hoechst staining, condensed chromatin of the apoptotic cells was observed in both cell lines. Conclusion: Centaurea albonites can be suggested for further cancer research studies.","PeriodicalId":16582,"journal":{"name":"Journal of Medicinal Plants","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70689193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatty acids composition of seed oils obtained from eight Iranian pomegranate cultivars","authors":"N. Momeni, H. A. Asadi-Gharneh","doi":"10.29252/JMP.20.77.26","DOIUrl":"https://doi.org/10.29252/JMP.20.77.26","url":null,"abstract":"Background: The pomegranate ( Punica granatum L.) is one of the oldest edible fruits that belongs to the Punicaceae family and different parts of it have been used as medicinal plant. The pomegranate seeds are the sources of lipid, sugars, protein and essential minerals. Objective: This study was planned to investigate the composition of fatty acids in seed oil of eight Iranian pomegranate cultivars. Methods: Mature ripe fruits of eight pomegranate cultivars were harvested from a commercial pomegranate orchard. Arils were dried via an air oven and oil extraction process was performed using Soxhlet apparatus with petroleum ether as solvent. Finally, identification of fatty acids in pomegranate seed oil was done by gas chromatography (GC). Results: A considerable variation was observed in the composition of fatty acids and oil content of pomegranate cultivars. The total oil content of the Iranian pomegranate cultivars was ranged from 10.81 g/100 g DW to 15.03 g/100 g DW palmitic acid (C16:0), stearic acid (C18:0), oleic acid (C18:1), linoleic acid (C18:2) and linolenic acid (C18:3) were major fatty acids in the Iranian pomegranate cultivars. Linolenic acid being considered and identified as the main fatty acid, ranged from 71.35 % for Poost-Ghermez to 74.58 % for Gar cultivars (P < 0.05). In saturated fatty acids, palmitic acid (C16:0) with a mean of 0.414 (g/100 g DW) and in unsaturated fatty acids, linolenic acid (C18:3) with a mean of 7.3 (g/100 g DW) were the dominant fatty acids found in studied pomegranates. Also, our results showed that Sorahi cultivar had the highest oil content (15.03 %), C18:1 (8.92 %) and C20:1 (1.12 %) among selected pomegranate cultivars. In pomegranate seed oil, 7.84 % of the fatty acid was saturated and 91.08 % was unsaturated. In addition, the ratio of polyunsaturated fatty acids to saturated ones were found 9.83 to 11.54. Conclusion: Eight cultivars of the Iranian pomegranate seed oils in this study contained very high levels of unsaturated fatty acids especially in linolenic acid. The quality obtained due to fatty acid composition can in turn enhance the general condition of the heath.","PeriodicalId":16582,"journal":{"name":"Journal of Medicinal Plants","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48100386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of cleaning and analytical method for determination of arbutin, hydroquinone and kojic acid in cosmetic products","authors":"Nilofar Eradati, F. Tajabadi, Hr Ahmadi-Ashtiani, Shamsali Rezazadeh, Mahdi Taherian, H. Rastegar","doi":"10.29252/JMP.20.77.50","DOIUrl":"https://doi.org/10.29252/JMP.20.77.50","url":null,"abstract":"Background: Hydroquinone, arbutin and kojic acid are herbal-based skin whitening compounds that are used in many cosmetics. Today, the lack of side effects of arbutin and kojic acid has made them a valuable alternative to hydroquinone. Due to the toxic effects of whitening compounds, it is necessary to control the amount of use of these in the whitening products","PeriodicalId":16582,"journal":{"name":"Journal of Medicinal Plants","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45938271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of wound healing and anti-inflammatory activities of a herbal ointment consisting of Althaea officinalis, Lavandula angustifolia, and Rosa x damascena in animal excision wound model","authors":"S. Momtaz, A. Abdolghaffari, E. Jasemi, Bahman Yaghoobvand, Saeed Esmaeilzadeh, A. Abdollahi, M. Abdollahi","doi":"10.29252/JMP.20.77.37","DOIUrl":"https://doi.org/10.29252/JMP.20.77.37","url":null,"abstract":"Background: Althaea officinalis L., Lavandula angustifolia Mill. and Rosa x damascena Herrm. are used to treat excision or burn lesions in traditional medicine. Objective: To evaluate the healing effect of a polyherbal ointment containing L. angustifolia, R. x damascena, and A. officinalis combination on wounds caused by third grade skin cut. Methods: To evaluate the wound healing effect of this polyherbal formulation, an ointment containing the extract of A. officinalis, the essential oil of R. x damascena (2 % essence) and the essential oil of L. officinalis (2 % essence) in an eucerin base (20:20:10:50) was prepared. The formulation was examined using excision wound test for 14 days and the percentage of healing effect in each group was calculated. Formalin induced rat hind paw edema method was used for determination of anti-inflammatory activities of the same formulation. Results: The percentage of recovery in the polyherbal formulation group was significantly higher than the other groups. Histological studies also confirmed these results. Herbal formulation treated group showed significant improvement in terms of re-epithelialization, angiogenesis, collagen deposition, and reducing inflammation. The percentage of wound healing was 99.07 ± 0.34, 99.22 ± 0.35, 98.45 ± 0.733, 98.75 ± 0.88 and 63.72 ± 5.64, for the polyherbal formulation, L. angustifolia, R. damascena, A. officinalis extracts, and the placebo group, respectively. Conclusion: This polyherbal formulation could act as a wound healing agent, possibly due to the suppression of inflammatory mediators. The presence of phenolic compounds might be a reason behind the therapeutic effect of these plants.","PeriodicalId":16582,"journal":{"name":"Journal of Medicinal Plants","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43673153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening of Apiaceae fruits discovered natural resources with considerable biological potential","authors":"Z. Tofighi, Mostafa Pirali Hamedani, S. Tavakoli, M. J. Tabatabaei, M. Rabei, S. Mohtadi, Farnoosh Mirghaffari, M. afshani, F. Kahrizi, B. Khodabandeloo, S. Jafari-Nodooshan, Mahdieh Shirzad, E. Motevaseli, S. Goodarzi","doi":"10.29252/jmp.19.76.46","DOIUrl":"https://doi.org/10.29252/jmp.19.76.46","url":null,"abstract":"Abbreviations: TE, Total methanol Extracts; PE, Petroleum Ether fraction; CL, Chloroform fraction; EA, Ethyl Acetate fraction; ME, Methanol residue fraction; BST, Brine Shrimp Test; FRAP, Ferric Reducing Antioxidant Power * Corresponding authors: goodarzi_s@sina.tums.ac.ir doi: 10.29252/jmp.19.76.46 Received 17 September 2019; Received in revised form 22 August 2020; Accepted 25 August 2020 © 2020. Open access. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/) Research Article","PeriodicalId":16582,"journal":{"name":"Journal of Medicinal Plants","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42300372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical and morpho-physiological variations in sea buckthorn (Hippophae rhamnoides L.) populations of Taleghan region in Iran","authors":"A. Kuhkheil, H. Naghdi Badi, A. Mehrafarin, V. Abdossi","doi":"10.29252/jmp.19.76.21","DOIUrl":"https://doi.org/10.29252/jmp.19.76.21","url":null,"abstract":"Phytochemical and morpho-physiological variations in sea buckthorn (Hippophae rhamnoides L.) populations of Taleghan region in Iran Ali Kuhkheil, Hassanali Naghdi Badi, Ali Mehrafarin*, Vahid Abdossi Department of Horticultural Science and Agronomy, Science and Research Branch, Islamic Azad University, Tehran, Iran Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran","PeriodicalId":16582,"journal":{"name":"Journal of Medicinal Plants","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45832467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancement of Taxol production by applying amino acid complex along with chitosan in suspension culture of Taxus baccata L.","authors":"Bahar Amirkavei Najafabadi, N. Qavami, M. Ebrahimi, P. Ebrahimi, N. Zarinpanjeh","doi":"10.29252/jmp.19.76.99","DOIUrl":"https://doi.org/10.29252/jmp.19.76.99","url":null,"abstract":"Enhancement of Taxol production by applying amino acid complex along with chitosan in suspension culture of Taxus baccata L. Bahar Amirkavei Najafabadi, Nassrin Qavami, Mohammad Ali Ebrahimi, Peyman Ebrahimi, Nasim Zarinpanjeh* 1 Department of Agricultural Biotechnology, Payam Noor University, Tehran, Iran 2 Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran 3 Agricultural Sciences and Food Industries Faculty, Science and Research Branch, Islamic Azad University, Tehran, Iran","PeriodicalId":16582,"journal":{"name":"Journal of Medicinal Plants","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48074635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in secondary metabolite contents of Arnica chamissonis Less. in response to different harvest time, flower developmental stages and drying methods","authors":"M. Asadi, S. Nejad Ebrahimi, M. Hatami, J. Hadian","doi":"10.29252/jmp.19.76.69","DOIUrl":"https://doi.org/10.29252/jmp.19.76.69","url":null,"abstract":"Changes in secondary metabolite contents of Arnica chamissonis Less. in response to different harvest time, flower developmental stages and drying methods Mojdeh Asadi, Samad Nejad Ebrahimi, Mehrnaz Hatami*, Javad Hadian 1 Department of Agriculture, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G.C., Tehran, Iran 2 Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G.C., Tehran, Iran 3 Department of Medicinal Plants, Faculty of Agriculture and Natural Resources, Arak University, Arak, Iran","PeriodicalId":16582,"journal":{"name":"Journal of Medicinal Plants","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46012531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of cytotoxic and antioxidant activities and phenol content of four Salvia L. species from Iran","authors":"M. Iravani, R. Mahinpour, Z. Zahraei, Zeinab Toluei, Fatemeh Asgari, N. Haghighipour","doi":"10.29252/jmp.19.76.59","DOIUrl":"https://doi.org/10.29252/jmp.19.76.59","url":null,"abstract":"","PeriodicalId":16582,"journal":{"name":"Journal of Medicinal Plants","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45613708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of lecithin on topical anti-inflammatory activity of turmeric (Curcuma longa L.) ointment","authors":"S. Esmaeili, Saleh Omid-Malayeri, H. Hajimehdipoor, H. Rasekh, H. Moghimi, Soheil Omid-Malayeri, R. Yaraee, M. Jalali Nadoushan","doi":"10.29252/jmp.19.76.89","DOIUrl":"https://doi.org/10.29252/jmp.19.76.89","url":null,"abstract":"The role of lecithin on topical anti-inflammatory activity of turmeric (Curcuma longa L.) ointment Somayeh Esmaeili, Saleh Omid-Malayeri, Homa Hajimehdipoor*, Hamid Reza Rasekh, Hamid Reza Moghimi, Soheil Omid-Malayeri, Roya Yaraee, Mohammad Reza Jalali Nadoushan Traditional Medicine and Materia Medica Research Center and Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran Department of Pharmacoeconomy & Administrative Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran Department of Pharmaceutics, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran Student Research Committee, School of Medicine, Shahed University, Tehran, Iran Department of Immunology, School of Medicine, Shahed University, Tehran, Iran Department of Pathology and Anatomy, School of Medicine, Shahed University, Tehran, Iran","PeriodicalId":16582,"journal":{"name":"Journal of Medicinal Plants","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49116431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}