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Nano Science in Pulmonary Drug Delivery 纳米科学在肺部给药
Journal of Nanosciences Research & Reports Pub Date : 2021-09-30 DOI: 10.47363/jnsrr/2021(3)122
B. Prajapati, Umang Varia
{"title":"Nano Science in Pulmonary Drug Delivery","authors":"B. Prajapati, Umang Varia","doi":"10.47363/jnsrr/2021(3)122","DOIUrl":"https://doi.org/10.47363/jnsrr/2021(3)122","url":null,"abstract":"Respiratory diseases are a common disease with high incidence all over the world, pose a serious threat to human health and are considered to be an economic and social burden. The application of nanotechnology in drug delivery systems has created new treatments for respiratory diseases. In this regard, this review has systematically introduced the physicochemical properties of nanoparticles (NP). We have reviewed the current state of research on various Nano carriers in the treatment of respiratory diseases, including liposomes, solid lipid Nano carriers, and polymer Nano carriers. The application of nanotechnology overcomes some of the deficiencies inherent in drugs and offers endless possibilities for the development of drugs for the treatment of respiratory diseases. However, most of the relevant research is in the preclinical stage and the assessment of safety remains a difficult task. Future research is needed to focus on changes in the performance, molecular mechanisms, and potential toxicity of therapeutic Nano medicines.","PeriodicalId":16545,"journal":{"name":"Journal of Nanosciences Research & Reports","volume":"184 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80480980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organic Inorganic Materials Open New Path for Synthesis and Application 有机无机材料为合成和应用开辟了新途径
Journal of Nanosciences Research & Reports Pub Date : 2021-06-30 DOI: 10.47363/jnsrr/2021(3)120
N. Omer
{"title":"Organic Inorganic Materials Open New Path for Synthesis and Application","authors":"N. Omer","doi":"10.47363/jnsrr/2021(3)120","DOIUrl":"https://doi.org/10.47363/jnsrr/2021(3)120","url":null,"abstract":"Hybrid smart materials, frame both inorganic and organic components, and their contribution in the designing of specific modern technologies are receiving more attention and interest due to their better improved solution process, controllable synthesis, and tunable chemical roperties. However, the focus problem of compatibility, solubility and aggregation is to be solved urgently, which inevitably limits them widely application. To this end, an inorganic–organic hybrid material with wide-band absorption is designed and prepared, that incorporates octavinyl-polyhedral oligomeric silsesquioxane (OV-POSS)with aminecontaining and cyan uric chloride (CC) to get our novel system OV-POSS-Amine-CC our structure, composition, and properties were characterized and evaluated, the system was prepared as anew path to synthesis novel enhanced hybrid to applied in many application.","PeriodicalId":16545,"journal":{"name":"Journal of Nanosciences Research & Reports","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73545532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obtaining Thin Films of Silicon-Carbon Method of Reactive Magnetron Sputtering are used as Solar Cells 用反应磁控溅射法制备硅碳薄膜制备太阳能电池
Journal of Nanosciences Research & Reports Pub Date : 2021-06-30 DOI: 10.47363/jnsrr/2021(3)121
B. Najafov, FP Abasov, RS Ibragimov, Baku c Azadlig Ave. Russia Industry
{"title":"Obtaining Thin Films of Silicon-Carbon Method of Reactive Magnetron Sputtering are used as Solar Cells","authors":"B. Najafov, FP Abasov, RS Ibragimov, Baku c Azadlig Ave. Russia Industry","doi":"10.47363/jnsrr/2021(3)121","DOIUrl":"https://doi.org/10.47363/jnsrr/2021(3)121","url":null,"abstract":"In the work of the various parameters studied film amorphous and nano-crystalline alloy silicon-carbon (а-nc-Si1-xCx :H (x=0÷1)) doped with phosphorus (PH3 ) and boron (B2 H6 ). Studied the properties of these films on different substrates derived from quartz, glass and Silicon-coated Fe, Al, Pd, Ni, Ti, Ag. Using transmission electron microscopy (TEM) studied the morphology obtained nano tubes. Also examine the structural properties of films by using infrared spectroscopy and x-ray diffraction of x-rays. Created by cascade solar cells area S = 1.2 cm2 and have a coefficient of 11.2%.","PeriodicalId":16545,"journal":{"name":"Journal of Nanosciences Research & Reports","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80856302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanotechnology and Nanoparticles in Contemporary Sciences 当代科学中的纳米技术和纳米颗粒
Journal of Nanosciences Research & Reports Pub Date : 2021-03-31 DOI: 10.47363/jnsrr/2021(3)118
Rc Jagessar
{"title":"Nanotechnology and Nanoparticles in Contemporary Sciences","authors":"Rc Jagessar","doi":"10.47363/jnsrr/2021(3)118","DOIUrl":"https://doi.org/10.47363/jnsrr/2021(3)118","url":null,"abstract":"Nonotechanology has been a rapidly growing field of advanced science at the inception of this century. Many problematic endeavours in sciences have been successfully overcome using nanoparticles. For example, a low risk solution using antibody modified bismuth nanoparticle, in combination with an X-ray dose equivalent to a chest X-ray specifically, has been shown to kill the common bacterium Pseudomonas aeruginosa in a set up designed to resemble a deep wound in human tissue. Nanosized gold particle could catalyse the oxidation of carbon monoxide better than anything previously known. Heparin functionalized nanoparticles have been use for targeted delivery of anti-malarial drugs. Heparin is abundant and cheap compared to treatments that involve antibodies, an important consideration, since malaria is most common in developing countries. A bone repairing nano-particle paste has been developed that promises faster repair of fractures and breakages. DNA containing two growth genes is encapsulated inside synthetic calcium phosphate nanoparticles. In a remarkable demonstration of the extreme limits of nanoscale engineering, researchers have used the tip of a scanning tunnelling microscope to cleave and form selected chemical bonds in a complex molecule. Many medicinal and industrial endeavours have seen the use of Nanotechnology. These and other more recent advances in nanotechnology will be presented at this conference","PeriodicalId":16545,"journal":{"name":"Journal of Nanosciences Research & Reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75562245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Cellulose Nanoparticles Synthesized by Acid Hydrolysis for Safe Applications 酸水解法制备纳米纤维素的安全性评价
Journal of Nanosciences Research & Reports Pub Date : 2020-12-31 DOI: 10.47363/JNSRR/2020(2)114
Prathima Prabhu Tumkur, Nicole Nazario Bayon, N. Gunasekaran, B. Lamani, K. Prabhakaran, Joseph C. Hall, G. Ramesh
{"title":"Evaluation of Cellulose Nanoparticles Synthesized by Acid Hydrolysis for Safe Applications","authors":"Prathima Prabhu Tumkur, Nicole Nazario Bayon, N. Gunasekaran, B. Lamani, K. Prabhakaran, Joseph C. Hall, G. Ramesh","doi":"10.47363/JNSRR/2020(2)114","DOIUrl":"https://doi.org/10.47363/JNSRR/2020(2)114","url":null,"abstract":"In the present study, cellulose nanoparticles were synthesized from waste cotton by acid hydrolysis method. Nanoparticles were obtained by the hydrolysis of pretreated cotton fibers with an acid mixture containing water, hydrochloric acid (HCl) and sulphuric acid (H2SO4). Characterization and biocompatibility studies of obtained cellulose nanoparticles were performed successfully. The morphological studies of cellulose nanoparticles were conducted by Field Emission Scanning Electron Microscopy (FESEM) and Transmission Electron Microscopy (TEM). Both showed that the cellulose nanoparticles synthesized from waste cotton measured approximately 100 - 200nm in diameter. Energy Dispersive X-ray Spectroscopic spectrum showed the elemental composition of the cellulose nanoparticles containing carbon and oxygen. Fourier Transform Infrared (FT-IR) spectroscopy spectrum revealed the presence of several characteristic peaks of cellulose nanoparticles. Human lung epithelial (Beas-2B) cells were used to assess the cytotoxicity and biocompatibility activity of cellulose nanoparticles. Cytotoxicity of cellulose nanoparticles was determined by 3-(4,5- Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) assay. Live/Dead viability assay was carried out to assess the biocompatibility of cellulose nanoparticles. Generation of Reactive Oxygen Species in Beas-2B cells incubated with cellulose nanoparticles was determined by Reactive Oxygen Species (ROS) assay. MTT and Live/Dead assays showed no significant induction of cell death even at higher concentrations (100 μg) upon exposure to Beas- 2B cells. ROS assay revealed that cellulose nanoparticles did not induce any reactive oxygen species that contribute to the oxidative stress and inflammation leading to various disease conditions. The results revealed that the cellulose nanoparticles have a great potential in a variety of commercial applications","PeriodicalId":16545,"journal":{"name":"Journal of Nanosciences Research & Reports","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83477305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Tumeurs Neuroendocrines
Journal of Nanosciences Research & Reports Pub Date : 2020-03-31 DOI: 10.47363/jnsrr/2020(2)103
Faiza Bereksi Reguig
{"title":"Tumeurs Neuroendocrines","authors":"Faiza Bereksi Reguig","doi":"10.47363/jnsrr/2020(2)103","DOIUrl":"https://doi.org/10.47363/jnsrr/2020(2)103","url":null,"abstract":"","PeriodicalId":16545,"journal":{"name":"Journal of Nanosciences Research & Reports","volume":"156 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88923636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Classification of Breast Cancer in the Region of Constantine: An Epidemiological Study 康斯坦丁地区乳腺癌分子分类:一项流行病学研究
Journal of Nanosciences Research & Reports Pub Date : 2020-03-31 DOI: 10.47363/JNSRR/2020(2)104
Sara Khelf, Leila Guedjali, S. Haddad, D. Satta
{"title":"Molecular Classification of Breast Cancer in the Region of Constantine: An Epidemiological Study","authors":"Sara Khelf, Leila Guedjali, S. Haddad, D. Satta","doi":"10.47363/JNSRR/2020(2)104","DOIUrl":"https://doi.org/10.47363/JNSRR/2020(2)104","url":null,"abstract":"Breast cancer (CS) is the most common female cancer worldwide, ranking first in Algeria for its frequency and mortality .Molecular classification has distinguished at least four molecular types: luminal A, luminal B, HER2 and basal-like. Our objective is to study the phenotypic profile of breast cancer in women with cancer as well as the different clinical, immunohistochemical and therapeutic aspects of different molecular groups.We undertook a retrospective study between October 2016 and December 2017. This study involved 121 files. The distribution of the population according to age showed that the most affected age group is [53-63] years old with 35%. Molecular classification results showed that the most common type was luminal A at 37.19%, followed by luminal type B at 27.27%, basal-like at 19.83%, and HER2 at 15.70%. Breast cancer of luminal type, expressing[ ER], accounts for 70 to 80% of all mammary carcinomas and that the luminal group A is the most common with proportions of 58 , 5% and 54.3% respectively while the distinction is observed in the other groups. Molecular classification plays a very important role in the treatment. This result shows that luminal type A is the most common, and that postmenopausal women are most likely to have breast cancer. This classification is very important in the orientation of the treatment. The resulting molecular classification is expected to better classify tumors to a personalized therapy. Breast cancer, molecular classification, immunohistochemistry, hormone receptors, HER2 status","PeriodicalId":16545,"journal":{"name":"Journal of Nanosciences Research & Reports","volume":"122 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74836544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of the Effect of Nanotechnology Drugs (mcs-b) on the Aggregation of Human Blood Platelets 纳米药物(mcs-b)对人血小板聚集作用的研究
Journal of Nanosciences Research & Reports Pub Date : 2019-12-31 DOI: 10.47363/jnsrr/2019(1)102
A. Belousov
{"title":"Study of the Effect of Nanotechnology Drugs (mcs-b) on the Aggregation of Human Blood Platelets","authors":"A. Belousov","doi":"10.47363/jnsrr/2019(1)102","DOIUrl":"https://doi.org/10.47363/jnsrr/2019(1)102","url":null,"abstract":"This scientific article is devoted to the study of the effect of magnetite nanoparticles (MCS-B brand) on the functional platelets activity of human. 0.9% NaCl was used as a control. The results of the study showed that the use of NaCl saline solution shifts the colloidal suspension equilibrium of platelets towards a significant (P<0.001) increase in the rate and index of their aggregation. For the first time, the effect of 0.9% NaCl on function of platelets makes us reconsider the concept of safety of infusion solutions in patients with initial signs of platelet disorders hemostasis. On the contrary, the use of MCS-B nanoparticles significantly revealed (P<0.05) an increase in the stability of colloidal suspension of platelets. This is an important pathogenetic factor which affects the occurrence of correction of hemostasis in conditions of blood clotting disorders","PeriodicalId":16545,"journal":{"name":"Journal of Nanosciences Research & Reports","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80562347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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