Journal of neurological surgery. Part A, Central European neurosurgery最新文献

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Local Prophylactic Teicoplanin Effect on Spinal Fusion Surgery: A Comparative Retrospective Study. 局部预防性替考拉宁对脊柱融合手术的影响:回顾性对比研究
IF 0.9 4区 医学
Journal of neurological surgery. Part A, Central European neurosurgery Pub Date : 2024-11-01 Epub Date: 2023-05-31 DOI: 10.1055/a-2103-7519
Nuh Mehmet Elmadağ, Deniz Kara, Anil Pulatkan, Vahdet Uçan, Dilek Hacer Cesme, Orkhan Aliyev, Hüseyin Doğu, Nail Demirel, Anas Abdallah
{"title":"Local Prophylactic Teicoplanin Effect on Spinal Fusion Surgery: A Comparative Retrospective Study.","authors":"Nuh Mehmet Elmadağ, Deniz Kara, Anil Pulatkan, Vahdet Uçan, Dilek Hacer Cesme, Orkhan Aliyev, Hüseyin Doğu, Nail Demirel, Anas Abdallah","doi":"10.1055/a-2103-7519","DOIUrl":"10.1055/a-2103-7519","url":null,"abstract":"<p><strong>Background: </strong> Surgical site infection (SSI) is one of the most severe complications of spinal fusion surgery that lead to increased morbidity and mortality rates. Prophylactic antibiotic usage is one of the methods that reduce the possibility of SSI in this procedure. The aim of this study was to determine the effect of local subfascial teicoplanin usage on radiologic and functional outcomes and compare it to the effect of vancomycin on surgical outcomes in patients who underwent decompression with posterior instrumentation (DPI) for lumbar spinal stenosis (LSS).</p><p><strong>Methods: </strong> Medical charts of patients with LSS who received DPI and met the study criteria were divided into three groups: the teicoplanin group included patients who underwent DPI with local teicoplanin before closure, the vancomycin group included patients who underwent DPI with local vancomycin, and the control group included patients who underwent DPI without any local prophylactic antibiotics.</p><p><strong>Results: </strong> A total of 101 patients were included in the study. No significant differences were found among groups regarding demographics, follow-up, and clinical and functional outcomes. No significant differences were observed among groups regarding postoperative improvements in SF-36-MCS, SF-36-PCS, Oswestry Disability Index, and Visual Analog Scale (VAS; <i>p</i> > 0.05). In the teicoplanin and vancomycin groups, the SSI rate was lower than that in the control group (2/35, 1/34, and 5/32, respectively, <i>p</i> = 0.136) without statistical significance; however, the postoperative fusion volume was significantly higher in the teicoplanin group when compared to the other groups (3.35 ± 1.08, 2.68 ± 1.17, and 2.65 ± 1.28 cm<sup>3</sup>, respectively, <i>p</i> = 0.007).</p><p><strong>Conclusions: </strong> Although its cost is relatively higher, teicoplanin was a good alternative to vancomycin in preventing SSIs with a higher fusion rate, but no superiority was observed regarding other outcomes.</p>","PeriodicalId":16544,"journal":{"name":"Journal of neurological surgery. Part A, Central European neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9616051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CD68 in Cerebral Aneurysms of Smokers and Nonsmokers: An Immunohistochemical Analysis. 吸烟者和不吸烟者脑动脉瘤中的 CD68:免疫组化分析
IF 0.9 4区 医学
Journal of neurological surgery. Part A, Central European neurosurgery Pub Date : 2024-11-01 Epub Date: 2023-08-16 DOI: 10.1055/a-2155-2166
Cassiano Ughini Crusius, Eduardo Cambruzzi, Marcelo Ughini Crusius, Paulo Henrique Pires de Aguiar, Alexandre Pereira Tognon, Paulo Sérgio Crusius, Marco Antônio Stefani
{"title":"CD68 in Cerebral Aneurysms of Smokers and Nonsmokers: An Immunohistochemical Analysis.","authors":"Cassiano Ughini Crusius, Eduardo Cambruzzi, Marcelo Ughini Crusius, Paulo Henrique Pires de Aguiar, Alexandre Pereira Tognon, Paulo Sérgio Crusius, Marco Antônio Stefani","doi":"10.1055/a-2155-2166","DOIUrl":"10.1055/a-2155-2166","url":null,"abstract":"<p><strong>Background: </strong> There is some evidence indicating that inflammation of the aneurysmal wall is related to aneurysmal growth and rupture. The presence of CD68 may indicate greater inflammatory activity. The objective of this study is to evaluate CD68 immunoexpression in surgically resected brain aneurysms and its association with smoking.</p><p><strong>Methods: </strong> The resected brain aneurysmal walls after microsurgical clipping were envoyed to immunohistochemistry investigation. The objective was to evaluate the expression of CD68 and CD34 antibodies. The associations between inflammatory markers, smoking, and rupture were tested using Fischer's exact test.</p><p><strong>Results: </strong> CD68 immunoexpression in the tunica media was associated with larger aneurysms: 7.0 mm (7.0-9.0 mm) versus 5.0 mm (3.5-5 mm; <i>p</i> = 0.011). There was no statistically significant association between smoking and CD68 expression in the tunica media (<i>p</i> = 0.234) or in either the tunica media or the tunica intima (<i>p</i> = 0.628). There was also no statistically significant association between hemorrhagic presentation of the aneurysm and CD68 expression in the tunica media (<i>p</i> = 0.689) or in either the tunica media or the tunica intima (<i>p</i> = 0.348). Therefore, the presence of CD68-positive cells in the aneurysmal walls indicates an association with size, especially if the tunica media is exclusively compromised (<i>p</i> = 0.011).</p><p><strong>Conclusion: </strong> Immunohistochemistry investigation for CD68 antibodies was used to determine histiocytic infiltration. Adequately powered studies are necessary to further investigate the association between CD68-positive cells and both smoking history and hemorrhagic presentation of aneurysms.</p>","PeriodicalId":16544,"journal":{"name":"Journal of neurological surgery. Part A, Central European neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10004972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Application of Ultrasound-guided Electrode Placement and Detection of Nerve Action Potential. 超声引导电极置入及神经动作电位检测的临床应用。
IF 0.9 4区 医学
Journal of neurological surgery. Part A, Central European neurosurgery Pub Date : 2024-11-01 Epub Date: 2022-05-03 DOI: 10.1055/a-1842-4343
Dong Han, Le Xu, Jianguang Xu
{"title":"Clinical Application of Ultrasound-guided Electrode Placement and Detection of Nerve Action Potential.","authors":"Dong Han, Le Xu, Jianguang Xu","doi":"10.1055/a-1842-4343","DOIUrl":"10.1055/a-1842-4343","url":null,"abstract":"<p><strong>Background: </strong> We explore a minimally invasive method (combined ultrasound detection, electrode placement and electrophysiologic nerve examination) to evaluate the early-stage quality of a nerve suture site.</p><p><strong>Methods: </strong> Ten patients with median and/or ulnar nerve injuries who had undergone nerve suture were recruited. Postoperative ultrasound examination found that the nerve injury was sutured. Then, a stimulating electrode and recording electrode were located beside the nerve proximal and distal to the suture site guided by ultrasound. Measurement of nerve action potentials (NAP) were performed with these electrodes, followed by surgical exploration. The pre- and intraoperative electrophysiologic findings were compared, together with amplitude, latency, and wave shape of NAP.</p><p><strong>Results: </strong> Of the 10 patients, 3 patients were diagnosed with median nerve injury, 2 with ulnar nerve injury, and 5 with the median nerve and ulnar nerve injury. NAP could not be detected pre- and intraoperatively in three median nerves from three patients and in two ulnar nerves from two patients. NAP was detected in 10 nerves from the remaining 5 patients. The pre- and intraoperative NAP results showed consistent results concerning the status of the nerve suture. Wilcoxon's signed-rank test indicated no significant difference in the amplitude and latency detected via sonographically placed electrodes and during surgical exploration. The number of negative-phase waves were equally distributed.</p><p><strong>Conclusion: </strong> Ultrasound-guided electrode placement and NAP detection can substitute surgery and serve as a minimally invasive approach to evaluate the regeneration of a sutured nerve.</p>","PeriodicalId":16544,"journal":{"name":"Journal of neurological surgery. Part A, Central European neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41236132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous Extradural Hematoma in a Sickle Cell Anemia Patient with Hyperinflammation and Thrombotic Microangiopathy Successfully Treated with Eculizumab: A Case Report and Review of the Literature. 镰状细胞贫血患者自发性硬膜外血肿,伴有过度炎症和血栓性微血管病,使用 Eculizumab 治疗成功:病例报告和文献综述。
IF 0.9 4区 医学
Journal of neurological surgery. Part A, Central European neurosurgery Pub Date : 2024-11-01 Epub Date: 2024-02-20 DOI: 10.1055/a-2271-8772
Michael Itak Ita, Pia Olesen, Maria Rosing, Morten Mørk, Halldór Bjarki Einarsson, Jens Jakob Riis
{"title":"Spontaneous Extradural Hematoma in a Sickle Cell Anemia Patient with Hyperinflammation and Thrombotic Microangiopathy Successfully Treated with Eculizumab: A Case Report and Review of the Literature.","authors":"Michael Itak Ita, Pia Olesen, Maria Rosing, Morten Mørk, Halldór Bjarki Einarsson, Jens Jakob Riis","doi":"10.1055/a-2271-8772","DOIUrl":"10.1055/a-2271-8772","url":null,"abstract":"<p><strong>Background: </strong> The event of extradural hematoma in the absence of head trauma is a rare central nervous system complication of sickle cell disease. We report here a case of spontaneous extradural hematoma in a patient being treated for sickle cell vasoocclusive crisis complicated by hyperinflammation and thrombotic microangiopathy. The significance of inflammation as an integral component of the pathomechanism of vasoocclusive crisis in patients with sickle cell disease and the role of heme in activating the complement system's alternative pathway are highlighted in this case report.</p><p><strong>Case presentation: </strong> A teenage patient with sickle cell disease developed a spontaneous right parietal extradural hematoma while receiving treatment for sickle cell vasoocclusive crisis. The concurrent events of hyperinflammation, disseminated intravascular coagulation, hyperhemolysis syndrome, thrombotic microangiopathy, and refractory postoperative bleeding complicated this patient's clinical course after surgical evacuation of extradural hematoma. This patient was subsequently treated with eculizumab and improved in the days following.</p><p><strong>Conclusion: </strong> Treatment with the anti-C5 monoclonal antibody eculizumab, which targets and inhibits terminal complement system activation, reversed the deleterious cascade of events in this patient with sickle cell disease.</p>","PeriodicalId":16544,"journal":{"name":"Journal of neurological surgery. Part A, Central European neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139912852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inside Out Cranioplasty: A Novel Technique for One-Stage Reconstruction of Persistent Scalp Necrosis. 颅内外成形术:持续性头皮坏死一期重建的新技术。
IF 0.9 4区 医学
Journal of neurological surgery. Part A, Central European neurosurgery Pub Date : 2024-11-01 Epub Date: 2023-03-14 DOI: 10.1055/a-2053-8491
Shigeomi Yokoya, Hideki Oka, Akihiko Hino
{"title":"Inside Out Cranioplasty: A Novel Technique for One-Stage Reconstruction of Persistent Scalp Necrosis.","authors":"Shigeomi Yokoya, Hideki Oka, Akihiko Hino","doi":"10.1055/a-2053-8491","DOIUrl":"10.1055/a-2053-8491","url":null,"abstract":"<p><strong>Background: </strong> Cranioplasty can be a challenging procedure in certain patients, such as those with scalp necrosis, or when performed after multiple surgical procedures. Herein, we present a patient in whom a part of the skull was placed inside out in a setting where the scalp wound could not be simply sutured because of multiple previous operations.</p><p><strong>Methods: </strong> A 66-year-old patient with a history of multiple craniotomies to resect an intracranial tumor suffered significant skin flap necrosis after harvesting the superficial temporal artery for a bypass intending to ligate the internal carotid artery. He subsequently underwent a one-stage reconstruction surgery, in which the central part of the bone was excised, turned over, and fixed at the inner plate of the bone flap on the outside, and the outer plate on the inside.</p><p><strong>Results: </strong> This technique reduced the skin tension and reduced the epidural dead space, allowing skin flap healing with acceptable cosmetic results.</p><p><strong>Conclusion: </strong> \"Inside out cranioplasty\" is a valid option for one-stage reconstruction in the cases with scalp necrosis.</p>","PeriodicalId":16544,"journal":{"name":"Journal of neurological surgery. Part A, Central European neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9984069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interleukin-6 in Spinal Cord Injury: Could Immunomodulation Replace Immunosuppression in the Management of Acute Traumatic Spinal Cord Injuries? 脊髓损伤中的白细胞介素-6:免疫调节能否取代免疫抑制治疗急性创伤性脊髓损伤?
IF 0.9 4区 医学
Journal of neurological surgery. Part A, Central European neurosurgery Pub Date : 2024-11-01 Epub Date: 2023-06-16 DOI: 10.1055/a-2111-5698
Hank Shipman, Molly Monsour, Madeline M Foley, Serge Marbacher, Davide M Croci, Erica F Bisson
{"title":"Interleukin-6 in Spinal Cord Injury: Could Immunomodulation Replace Immunosuppression in the Management of Acute Traumatic Spinal Cord Injuries?","authors":"Hank Shipman, Molly Monsour, Madeline M Foley, Serge Marbacher, Davide M Croci, Erica F Bisson","doi":"10.1055/a-2111-5698","DOIUrl":"10.1055/a-2111-5698","url":null,"abstract":"<p><p>Traumatic spinal cord injuries (SCI) result in devastating impairment to an individual's functional ability. The pathophysiology of SCI is related to primary injury but further propagated by secondary reactions to injury, such as inflammation and oxidation. The inflammatory and oxidative cascades ultimately cause demyelination and Wallerian degeneration. Currently, no treatments are available to treat primary or secondary injury in SCI, but some studies have shown promising results by lessening secondary mechanisms of injury. Interleukins (ILs) have been described as key players in the inflammation cascade after neuronal injury; however, their role and possible inhibition in the context of acute traumatic SCIs have not been widely studied. Here, we review the relationship between SCI and IL-6 concentrations in the CSF and serum of individuals after traumatic SCIs. Furthermore, we explore the dual IL-6 signaling pathways and their relevance for future IL-6 targeted therapies in SCI.</p>","PeriodicalId":16544,"journal":{"name":"Journal of neurological surgery. Part A, Central European neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9647223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transforaminal Endoscopic Lumbar Diskectomy versus Open Microdiskectomy for Symptomatic Lumbar Disk Herniation: A Comparative Cohort Study on Costs and Long-Term Outcomes. 经椎间孔内镜下腰椎间盘切除术与开放式椎间盘切除术治疗症状性腰椎间盘突出症:成本和长期结果的比较队列研究。
IF 0.9 4区 医学
Journal of neurological surgery. Part A, Central European neurosurgery Pub Date : 2024-11-01 Epub Date: 2023-10-25 DOI: 10.1055/s-0043-1775760
Sajjad Saghebdoust, Farshid Khadivar, Mehran Ekrami, Mohammad Ali Abouei Mehrizi, Amir Valinezhad Lajimi, Mohammad Reza Rouhbakhsh Zahmatkesh, Neda Pak, Morteza Faghih Jouibari, Seyed Shahab Ghazi Mirsaeed, Mohammad Reza Boustani
{"title":"Transforaminal Endoscopic Lumbar Diskectomy versus Open Microdiskectomy for Symptomatic Lumbar Disk Herniation: A Comparative Cohort Study on Costs and Long-Term Outcomes.","authors":"Sajjad Saghebdoust, Farshid Khadivar, Mehran Ekrami, Mohammad Ali Abouei Mehrizi, Amir Valinezhad Lajimi, Mohammad Reza Rouhbakhsh Zahmatkesh, Neda Pak, Morteza Faghih Jouibari, Seyed Shahab Ghazi Mirsaeed, Mohammad Reza Boustani","doi":"10.1055/s-0043-1775760","DOIUrl":"10.1055/s-0043-1775760","url":null,"abstract":"<p><strong>Background: </strong> Transforaminal endoscopic lumbar diskectomy (TELD) is considered an effective treatment for lumbar disk herniation (LDH). There is a paucity of studies comparing in detail the costs and long-term clinical outcomes of TELD and open microdiskectomy (MD), especially in developing countries. Thus, we sought to provide a multidimensional insight into this matter by comparing the direct costs and long-term outcomes of TELD with those of MD.</p><p><strong>Methods: </strong> The electronic health records of 434 patients with LDH who underwent either TELD or MD were collected from February 2011 to October 2014. Within a 7-year follow-up period, 412 patients, comprising 203 patients treated with TELD and 209 patients treated with MD, were fully evaluated. Patient characteristics, operative time, intraoperative blood loss (IBL), postoperative hospital stay, time to return to work (RTW), perioperative complications, and direct costs were collected. Clinical outcomes were assessed using the Visual Analog Scale (VAS), Oswestry Disability Index (ODI), and modified MacNab criteria.</p><p><strong>Results: </strong> The postoperative ODI and VAS scores improved significantly in both groups (<i>p</i> < 0.001). In accordance with the modified MacNab criteria, the rate of excellent and good outcomes was 88.67 and 88.03% in the TELD and MD groups, respectively. There were no significant differences between the groups in the clinical outcomes and perioperative complications. However, IBL, hospital stay, and RTW were significantly reduced in the TELD group (<i>p</i> < 0.05). Twenty-one cases in the TELD group and nine in the MD group underwent reoperation due to recurrence (<i>p</i> < 0.05). Total inpatient cost per patient was $1,596 in the TELD group and $1,990 in the MD group (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong> TELD for the treatment of symptomatic LDH could be an affordable strategy, providing certain advantages of minimally invasive procedures such as shorter hospital stay and earlier recovery along with comparable clinical outcomes to the conventional surgical method.</p>","PeriodicalId":16544,"journal":{"name":"Journal of neurological surgery. Part A, Central European neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50161894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Course after End-of-Life Decisions on a Neurosurgical Ward: Much to Learn and Improve. 神经外科病房生命终结决定后的临床过程:需要学习和改进的地方还有很多。
IF 0.9 4区 医学
Journal of neurological surgery. Part A, Central European neurosurgery Pub Date : 2024-11-01 Epub Date: 2024-07-03 DOI: 10.1055/s-0043-1771278
Xenia Hautmann, Veit Rohde, Christian von der Brelie
{"title":"Clinical Course after End-of-Life Decisions on a Neurosurgical Ward: Much to Learn and Improve.","authors":"Xenia Hautmann, Veit Rohde, Christian von der Brelie","doi":"10.1055/s-0043-1771278","DOIUrl":"10.1055/s-0043-1771278","url":null,"abstract":"<p><strong>Background: </strong> End-of-life (EoL) decisions are routine in neurosurgical care due to frequent devastating and life-threatening diagnoses. Advance directives, discussions with patients' relatives, and evaluation of the alleged will of the patient play an increasing important role in clinical decision-making. Institutional standards, ethical values, different ethnical backgrounds, and individual physician's experiences influence clinical judgments and decisions. We hypothesize that the implementation of palliative care in neurosurgical wards needs optimization. The aim of this study is to identify possible sources of error and to share our experiences.</p><p><strong>Methods: </strong> This is a retrospective observational analysis. One hundred and sixty-eight patients who died on a regular neurosurgical ward between 2014 and 2019 were included. Medical reports were analyzed in detail. A differentiation between consistent and nonconsistent palliation was made, with consistent palliative care consisting of discontinuation of medication that was no longer indicated, administration of medication for symptom control, and consequent discontinuation of nutrition and fluid substitution that went beyond satisfying hunger or thirst.</p><p><strong>Results: </strong> EoL decisions were made in 127 (84.1%) of all 168 cases; 100 patients were included in our analysis. Of these patients, only 24 had an advance directive, and the relatives were included in the communication about the therapy goals in 71 cases. Discontinuation of medication that is not for symptom control was performed in 63 patients, food withdrawal in 66 patients, and fluid substitution that went beyond the quenching of thirst was withdrawn in 27 patients. Thus, consistent palliative care was realized in 25% of all patients. The mean duration from the EoL decision until death was 2.1 days (range: 0-20 days). If a consistent palliative care was carried out, patients survived significantly shorter (nonconsistent palliative care: 2.4 days; range: 0-10 days vs. consistent palliative care: 1.2 days; range: 0-4 days; <i>p</i> = 0.008).</p><p><strong>Conclusions: </strong> The therapy goal should be thoroughly considered and determined at an early stage. If an EoL decision is reached, consistent palliative care should be carried out in order to limit suffering of moribund patients.</p>","PeriodicalId":16544,"journal":{"name":"Journal of neurological surgery. Part A, Central European neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traumatic Spinal Cord Injury in Children: Clinical Profile and Management Outcome in a Developing Country's Rural Neurosurgery Practice. 儿童创伤性脊髓损伤:发展中国家农村神经外科的临床概况和管理结果。
IF 0.9 4区 医学
Journal of neurological surgery. Part A, Central European neurosurgery Pub Date : 2024-11-01 Epub Date: 2023-01-14 DOI: 10.1055/a-2013-3278
Toyin Ayofe Oyemolade, Amos Olufemi Adeleye, Inwonoabasi Nicholas Ekanem, Adeyemi Damilola Ogunoye
{"title":"Traumatic Spinal Cord Injury in Children: Clinical Profile and Management Outcome in a Developing Country's Rural Neurosurgery Practice.","authors":"Toyin Ayofe Oyemolade, Amos Olufemi Adeleye, Inwonoabasi Nicholas Ekanem, Adeyemi Damilola Ogunoye","doi":"10.1055/a-2013-3278","DOIUrl":"10.1055/a-2013-3278","url":null,"abstract":"<p><strong>Background: </strong> There is paucity of data-driven study on pediatric traumatic spinal cord injury (SCI) in the developing countries. This study aims to define the clinical profile of pediatric traumatic SCI in a rural tertiary hospital in a sub-Saharan African country.</p><p><strong>Methods: </strong> This was a prospective observational study of all children with spinal cord injury managed at our center over a 42-month period.</p><p><strong>Results: </strong> There were 20 patients, comprising 13 males and 7 females with a mean age of 11.5 years. Road traffic crash was the cause in 70% of the cases (motorcycle accident = 45%), and fall from height in 25%. Pedestrians were the victims of the road traffic crash in 42.9% (6/14) of the cases, while 21.4% (3/14) and 28.6% (4/14) were passengers on motorcycles and in motor vehicles, respectively. The cervical spine was the most common location of injury, occurring in 90% of the cases (18/20). Seventy-five percent of the patients (15/20) had transient deficits, but were grossly normal neurologically on examination (American Spinal Cord Injury Association [ASIA] grade E); 2 patients had ASIA D, while 1 patient each had ASIA C, B, and A injuries. All patients were managed nonoperatively. The patients with incomplete deficits improved, while those with complete injury did not make any motor or sensory gain.</p><p><strong>Conclusion: </strong> Road traffic accident, mostly motorcycle crash, was the most common etiology of pediatric SCI in this series, and most of the injuries were located in the cervical spine. Disabling injury constituted a small proportion of pediatric SCI in our practice.</p>","PeriodicalId":16544,"journal":{"name":"Journal of neurological surgery. Part A, Central European neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10286779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed Internal Carotid Artery Dissection Mimicking Cerebral Vasospasms after Subarachnoid Hemorrhage: A Case Report. 蛛网膜下腔出血后模仿脑血管痉挛的延迟性颈内动脉交叉:病例报告。
IF 0.9 4区 医学
Journal of neurological surgery. Part A, Central European neurosurgery Pub Date : 2024-11-01 Epub Date: 2023-08-18 DOI: 10.1055/a-2156-5181
Tim Lampmann, Franziska Dorn, Arndt-Hendrik Schievelkamp, Mohammed Banat, Hartmut Vatter, Motaz Hamed
{"title":"Delayed Internal Carotid Artery Dissection Mimicking Cerebral Vasospasms after Subarachnoid Hemorrhage: A Case Report.","authors":"Tim Lampmann, Franziska Dorn, Arndt-Hendrik Schievelkamp, Mohammed Banat, Hartmut Vatter, Motaz Hamed","doi":"10.1055/a-2156-5181","DOIUrl":"10.1055/a-2156-5181","url":null,"abstract":"<p><strong>Background: </strong> Delayed cerebral ischemia (DCI) is usually caused by cerebral vasospasm (CVS). To detect DCI and CVS, a cranial computed tomography (CT) scan will be performed, but cervical vessels are not necessarily displayed.</p><p><strong>Methods: </strong> A 63-year-old female patient who suffered from aneurysmal subarachnoid hemorrhage (SAH) was treated at the authors' institution. After an initially unremarkable clinical course, she developed aphasia on day 11. CT angiography (CTA) and perfusion imaging revealed significant hypoperfusion of the left hemisphere. In addition, the CTA showed a subtotal stenosis of the internal carotid artery (ICA) at the level of the petrous segment, suspicious for a dissection. This was not detectable angiographically in the final control of the intervention and was also not clinically evident until day 11.</p><p><strong>Results: </strong> Cerebral perfusion as well as the clinical symptoms normalized rapidly after stent reconstruction of the ICA.</p><p><strong>Conclusion: </strong> Even though CVS is the most common cause of hypoperfusion in patients after an SAH, a peri-interventional dissection can also lead to relevant stenosis and thus to a disturbed cerebral perfusion and corresponding neurologic deficits. The time delay between the intervention and the clinical and CTA manifestation in our case is remarkable.</p>","PeriodicalId":16544,"journal":{"name":"Journal of neurological surgery. Part A, Central European neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10082621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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