Journal of Neurology and Neurophysiology最新文献

{"title":"An electrophysiological diagram: Components in diabetic cardiomyopathy Its Care","authors":"K. Reddy","doi":"10.35248/2155-9562.21.12.512","DOIUrl":"https://doi.org/10.35248/2155-9562.21.12.512","url":null,"abstract":"There's a developing body of prove that Diabetes Mellitus leads to a particular cardiomyopathy separated from vascular malady and bring almost tall dreariness and mortality all through the world. Later clinical and exploratory thinks about have broadly illustrated that this cardiomyopathy causes disabled cardiac execution showed by early diastolic and late systolic brokenness. This impeded cardiac execution most likely have risen upon the expression and movement of administrative proteins such as Na+/Ca2+ exchanger, sarcoplasmic reticulum Ca2+-ATPase, ryanodine receptor and phospholamban. Inorganic components have been recommended to have anti-diabetic impacts due to their recommended capacity to control glucose homeostasis, decrease oxidative stretch or smother phosphatases.","PeriodicalId":16455,"journal":{"name":"Journal of Neurology and Neurophysiology","volume":"27 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74799128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Axons & There Function","authors":"Xing Gros","doi":"10.35248/2155-9562.21.12.536","DOIUrl":"https://doi.org/10.35248/2155-9562.21.12.536","url":null,"abstract":"","PeriodicalId":16455,"journal":{"name":"Journal of Neurology and Neurophysiology","volume":"32 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79399106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex contrasts in neuro(auto)immunity and inveterate sciatic nerve torment","authors":"K. Shivani","doi":"10.35248/2155-9562.21.12.519","DOIUrl":"https://doi.org/10.35248/2155-9562.21.12.519","url":null,"abstract":"Incessant torment happens with more noteworthy recurrence in ladies, with a parallel sexually dimorphic slant detailed in sufferers of numerous immune system infections. There's a ought to proceed looking at neuro-immuneendocrine crosstalk within the setting of sexual dimorphisms in persistent torment. A few wonders in specific ought to be advance investigated. In patients, autoantibodies to neural antigens have been related with tangible pathway hyper-excitability, and the part of self-antigens discharged by harmed nerves remains to be characterized. In expansion, particular safe cells discharge pro-nociceptive cytokines that specifically impact neural terminating, whereas T lymphocytes actuated by particular antigens discharge variables that either back nerve repair or compound the harm. Tweaking particular safe cell populaces might hence be a implies to advance nerve recuperation, with sex-specific results. Understanding natural sex contrasts that keep up, or come up short to preserve, neuroimmune homeostasis may educate the determination of sex-specific treatment regimens, progressing inveterate torment administration by rebalancing neuroimmune input. To move forward the quality of life for numerous patients who adapt day by day with torment, fitting disease-modifying methodologies that look at organic hazard components, such as age, hereditary qualities, and sex, got to be all around executed. Usually particularly relevant, given that the physiological frameworks that are annoyed in a state of determined torment include complex systems, counting the anxious and safe frameworks, endocrine input, and the vasculature. In arrange to altogether move forward wellbeing results, not as it were for torment but too for a extend of conditions, a developing agreement is that organic sex contrasts must be tended to, over logical disciplines. A all encompassing see will give an made strides understanding of how torment creates and gets to be constant, and how men and ladies react in an unexpected way to nociceptive signaling as well as to medications pointed at controling signals that ended up distorted.","PeriodicalId":16455,"journal":{"name":"Journal of Neurology and Neurophysiology","volume":"56 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85513085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of Diabetic Neuritis","authors":"Cennet Alper","doi":"10.35248/2155-9562.21.12.544","DOIUrl":"https://doi.org/10.35248/2155-9562.21.12.544","url":null,"abstract":"Diabetic polyneuropathy is the most common neuropathy in developed countries. Prevalence is a function of disease duration, and a reasonable figure, based upon several large studies, is that approximately 50 percent of patients with diabetes will eventually develop neuropathy[1]. Epidemiologic studies of diabetic neuropathy have provided heterogeneous results, owing to different patient populations, definitions of neuropathy used, and methods of assessments. Prediabetes is also associated with neuropathy.11 In the San Luis Valley cohort,12 the prevalence of peripheral neuropathy in patients with diabetes was 25.8%, as compared to 11.2% in subjects with impaired glucose tolerance (IGT) and 3.9% in control subjects. The Monitoring trends and determinants in CArdiovascular/Cooperative Research in the Region of Augsburg (MONICA/KORA)13 investigators found the prevalence of neuropathic pain to be 13.3% in patients with diabetes versus 8.7%, 4.2%, and 1.2% in subjects with IGT, impaired fasting glucose, and controls, respectively.","PeriodicalId":16455,"journal":{"name":"Journal of Neurology and Neurophysiology","volume":"69 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84267986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 63 Year Old Male with Atypical Presentation of Viral Meningitis","authors":"Allen M. Quirit","doi":"10.35248/2155-9562.21.12.546","DOIUrl":"https://doi.org/10.35248/2155-9562.21.12.546","url":null,"abstract":"Viral meningitis usually present with headache, fever and signs of meningeal irritation in immunocompetent adult. Nuchal rigidity and profound alteration of consciousness usually present. Viral meningitis may remain a diagnostic enigma without molecular techniques. Rapid molecular assays are the great advancement for the diagnosis of difficult to grow pathogens such as viruses and thus can become a big tool in antimicrobial stewardship. We presented a case of B.E a 63 years old male, worked as engineer came in with chief complaint of fever, intermittent for four days. No other associated symptoms noted such as headache, blurring and body weakness. After 3 days of hospitalization, still with intermittent fever without any associated complaints. On succeeding days of admission, patient developed sudden generalized body weakness and photophobia. All laboratory exam such as CT scan, electrolytes and complete blood count revealed normal. Vital signs and Physical examination were unremarkable. Lumbar puncture was done on 6th hospital day due to classic symptoms of meningitis such as photophobia and headache. The diagnosis was concluded as viral meningitis based on clinical presentation and CSF fluid analysis. Phadebac was requested after CSF analysis and no microorganisms were isolated. Patient was managed accordingly with acyclovir, steroids and mannitol. The neurologist and infectious disease specialist signed out the case as viral meningitis with conclusive laboratory result.","PeriodicalId":16455,"journal":{"name":"Journal of Neurology and Neurophysiology","volume":"26 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82252450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causes and Management of Rett Syndrome","authors":"Karl Hauns","doi":"10.35248/2155-9562.21.12.542","DOIUrl":"https://doi.org/10.35248/2155-9562.21.12.542","url":null,"abstract":"Rett condition (RTT) is a hereditary problem that regularly gets evident following 6–year and a half old enough in females. Manifestations remember disabilities for language and coordination and tedious movements.Those influenced frequently have more slow development, trouble strolling, and a more modest head size. Inconveniences of Rett condition can incorporate seizures, scoliosis, and dozing issues. The seriousness of the condition is variable[1]. Hereditarily, Rett condition (RTT) is brought about by transformations in the quality MECP2 situated on the X chromosome (which is engaged with transcriptional quieting and epigenetic guideline of methylated DNA), and can emerge inconsistently or from germline changes. In under 10% of RTT cases, transformations in the qualities CDKL5 or FOXG1 have additionally been found to take after it.[medical reference needed] Rett disorder is at first analyzed by clinical perception, yet the analysis is authoritative when there is a hereditary imperfection in the MECP2 quality.","PeriodicalId":16455,"journal":{"name":"Journal of Neurology and Neurophysiology","volume":"1 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90788017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Short note on Neonatal Brain Harm","authors":"Hatada Birgit","doi":"10.35248/2155-9562.21.12.531","DOIUrl":"https://doi.org/10.35248/2155-9562.21.12.531","url":null,"abstract":"Fetal/neonatal brain harm is an vital cause of neurological incapacity. Hypoxia-ischemia and excitotoxicity are considered critical insuperable, and, in show disdain toward of their intense nature, brain harm creates over an extended time period amid the essential, auxiliary, and tertiary stages. The concept that most of the damage creates with a delay after the offended makes it conceivable to supply compelling neuroprotective treatment after the offended. Undoubtedly, hypothermia connected inside 6 hours after birth in neonatal encephalopathy decreases neurological incapacity in clinical trials. In arrange to create the following generation of treatment, we ought to know more around the pathophysiological instrument amid the auxiliary and tertiary stages of harm.","PeriodicalId":16455,"journal":{"name":"Journal of Neurology and Neurophysiology","volume":"8 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90970284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expectation as a Compassionate and Business Commitment from Human Cognitive Neuroscience","authors":"Powell Beth","doi":"10.35248/2155-9562.21.12.526","DOIUrl":"https://doi.org/10.35248/2155-9562.21.12.526","url":null,"abstract":"Neuroimaging has incredibly upgraded the cognitive neuroscience understanding of the human brain and its variety over people (neurodiversity) in both wellbeing and infection. Such advance has not however, in any case, impelled changes in instructive or therapeutic hones that make strides people’s lives. We audit neuroimaging discoveries in which introductory brain measures (neuromarkers) are related with or anticipate future (1) instruction, learning, and execution in children and grown-ups; (2) culpability; (3) health-related behaviors; and (4) reactions to pharmacological or behavioral medicines. Neuromarkers regularly give way better expectations (neuroprognosis), alone or in combination with other measures, than conventional behavioral measures.","PeriodicalId":16455,"journal":{"name":"Journal of Neurology and Neurophysiology","volume":"1 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89941356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebrospinal Fluid & Its Structure","authors":"J. Moro","doi":"10.35248/2155-9562.20.12.522","DOIUrl":"https://doi.org/10.35248/2155-9562.20.12.522","url":null,"abstract":"The CSF is created by particular ependymal cells within the choroid plexuses of the ventricles of the brain, and retained within the arachnoid granulations. There's around 125 mL of CSF at any one time, and approximately 500 mL is created each day. CSF acts as a pad or buffer, providing basic mechanical and immunological security to the brain interior the cranium. CSF too serves a imperative work within the cerebral autoregulation of cerebral blood stream.","PeriodicalId":16455,"journal":{"name":"Journal of Neurology and Neurophysiology","volume":"46 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90551456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oligodendrocytes, Composition & Function","authors":"P. Vasudev","doi":"10.35248/2155-9562.20.12.525","DOIUrl":"https://doi.org/10.35248/2155-9562.20.12.525","url":null,"abstract":"Oligodendrocytes (from Greek 'cells with many branches'), or oligodendroglia, are a type of neuroglia whose fundamental capacities are to supply back and cover to axons within the central anxious framework of a few vertebrates, proportionate to the work performed by Schwann cells within the fringe anxious framework. Oligodendrocytes do this by making the myelin sheath. A single oligodendrocyte can amplify its forms to 50 axons, wrapping roughly 1 μm of myelin sheath around each axon; Schwann cells, on the other hand, can wrap around as it were one axon. Each oligodendrocyte shapes one fragment of myelin for a few adjoining axons. Oligodendrocytes were These","PeriodicalId":16455,"journal":{"name":"Journal of Neurology and Neurophysiology","volume":"26 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78238382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}