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Journal of Neuropathology & Experimental Neurology最新文献

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Stirling Carpenter, MD February 27, 1929–February 19, 2021 斯特林·卡朋特博士1929年2月27日- 2021年2月19日
Journal of Neuropathology & Experimental Neurology Pub Date : 2022-02-22 DOI: 10.1093/jnen/nlac005
R. Auer
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引用次数: 0
William G. Ellis, MD June 12, 1932–January 16, 2021 威廉·g·埃利斯，医学博士1932年6月12日至2021年1月16日
Journal of Neuropathology & Experimental Neurology Pub Date : 2021-07-27 DOI: 10.1093/jnen/nlab063
Heidi Ellis, G. M. Murphy, S. Salamat, R. Sobel
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引用次数: 0
Autobiography Series: A Life of Anecdotes 自传系列:轶事人生
Journal of Neuropathology & Experimental Neurology Pub Date : 2021-06-04 DOI: 10.1093/JNEN/NLAB021
P. Gambetti
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引用次数: 0
Meritorious Contributions to Neuropathology 对神经病理学的杰出贡献
Journal of Neuropathology & Experimental Neurology Pub Date : 2020-08-22 DOI: 10.1093/jnen/nlaa078
{"title":"Meritorious Contributions to Neuropathology","authors":"","doi":"10.1093/jnen/nlaa078","DOIUrl":"https://doi.org/10.1093/jnen/nlaa078","url":null,"abstract":"","PeriodicalId":16434,"journal":{"name":"Journal of Neuropathology & Experimental Neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79933751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Memoriam: Carol Petito, MD 纪念:卡罗尔·佩蒂托，医学博士
Journal of Neuropathology & Experimental Neurology Pub Date : 2019-11-01 DOI: 10.1093/JNEN/NLZ095
M. Hart
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引用次数: 0
2019 Recipients—Eileen H. Bigio, MD and Raymond A. Sobel, MD 2019年收件人:eileen H. Bigio, MD和Raymond A. Sobel, MD
Journal of Neuropathology & Experimental Neurology Pub Date : 2019-08-12 DOI: 10.1093/jnen/nlz065
{"title":"2019 Recipients—Eileen H. Bigio, MD and Raymond A. Sobel, MD","authors":"","doi":"10.1093/jnen/nlz065","DOIUrl":"https://doi.org/10.1093/jnen/nlz065","url":null,"abstract":"","PeriodicalId":16434,"journal":{"name":"Journal of Neuropathology & Experimental Neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80588919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Susan M. Staugaitis, MD, PhD January 19, 1957–August 6, 2018 Susan M. Staugaitis，医学博士，1957年1月19日至2018年8月6日
Journal of Neuropathology & Experimental Neurology Pub Date : 2019-03-25 DOI: 10.1093/jnen/nlz024
{"title":"Susan M. Staugaitis, MD, PhD January 19, 1957–August 6, 2018","authors":"","doi":"10.1093/jnen/nlz024","DOIUrl":"https://doi.org/10.1093/jnen/nlz024","url":null,"abstract":"","PeriodicalId":16434,"journal":{"name":"Journal of Neuropathology & Experimental Neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77135607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
William Carl Schoene, MD 1937–2017
Journal of Neuropathology & Experimental Neurology Pub Date : 2018-09-27 DOI: 10.1093/jnen/nly084
{"title":"William Carl Schoene, MD 1937–2017","authors":"","doi":"10.1093/jnen/nly084","DOIUrl":"https://doi.org/10.1093/jnen/nly084","url":null,"abstract":"","PeriodicalId":16434,"journal":{"name":"Journal of Neuropathology & Experimental Neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79428725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2018 Recipients—Brian Harding, DPhil, MA, BM, BCh, FRCPath and Hannah C. Kinney, MD 2018年获奖者:brian Harding, phd, MA, BM, BCh, FRCPath和Hannah C. Kinney, MD
Journal of Neuropathology & Experimental Neurology Pub Date : 2018-07-19 DOI: 10.1093/jnen/nly067
{"title":"2018 Recipients—Brian Harding, DPhil, MA, BM, BCh, FRCPath and Hannah C. Kinney, MD","authors":"","doi":"10.1093/jnen/nly067","DOIUrl":"https://doi.org/10.1093/jnen/nly067","url":null,"abstract":"","PeriodicalId":16434,"journal":{"name":"Journal of Neuropathology & Experimental Neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78913187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Quantitative Analysis of Brain Soluble Tau and the Tau Secretion Factor 脑可溶性Tau蛋白及其分泌因子的定量分析
Journal of Neuropathology & Experimental Neurology Pub Date : 2017-01-01 DOI: 10.1093/jnen/nlw105
Pengcheng Han, G. Serrano, T. Beach, R. Caselli, Junxiang Yin, Ningning Zhuang, Jiong Shi
{"title":"A Quantitative Analysis of Brain Soluble Tau and the Tau Secretion Factor","authors":"Pengcheng Han, G. Serrano, T. Beach, R. Caselli, Junxiang Yin, Ningning Zhuang, Jiong Shi","doi":"10.1093/jnen/nlw105","DOIUrl":"https://doi.org/10.1093/jnen/nlw105","url":null,"abstract":"Neurofibrillary tangles (NFTs) represent products of insoluble tau protein in the brains of patients with Alzheimer disease (AD). The cerebrospinal fluid (CSF) tau level is a biomarker in AD diagnosis. The soluble portion of tau protein in brain parenchyma is presumably the source for CSF tau but this has not previously been quantified. We measured CSF tau and soluble brain tau at autopsy in temporal and frontal brain tissue samples from 7 cognitive normal, 12 mild cognitively impaired, and 19 AD subjects. Based on the measured brain soluble tau, we calculated the whole brain tau load and estimated tau secretion factor. Our results suggest that the increase in NFT in AD is likely attributable to post-translational processes; the increase in CSF tau in AD patients is due to an accelerated carrier-based secretion. Moreover, cognitive dysfunction assessed by final Mini-Mental State Examination scores correlated with the secretion factor but not with the soluble tau.","PeriodicalId":16434,"journal":{"name":"Journal of Neuropathology & Experimental Neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80698493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
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